CN101411645A - The uniform radio-frequency ablation electrode of surface temperature - Google Patents

The uniform radio-frequency ablation electrode of surface temperature Download PDF

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Publication number
CN101411645A
CN101411645A CNA2007100472638A CN200710047263A CN101411645A CN 101411645 A CN101411645 A CN 101411645A CN A2007100472638 A CNA2007100472638 A CN A2007100472638A CN 200710047263 A CN200710047263 A CN 200710047263A CN 101411645 A CN101411645 A CN 101411645A
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China
Prior art keywords
radio
radio frequency
ablation electrode
frequency
gas
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CNA2007100472638A
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Chinese (zh)
Inventor
杨鹏飞
常兆华
柴东
梅勤智
盛亮亮
戴海雄
苏颖颖
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SHANGHAI DAOXIANG MEDICAL SYSTEM CO Ltd
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SHANGHAI DAOXIANG MEDICAL SYSTEM CO Ltd
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Priority to CNA2007100472638A priority Critical patent/CN101411645A/en
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Abstract

The invention provides the uniform radio-frequency ablation electrode of a kind of surface temperature, comprise radio frequency pin, control harvester, gas container, discharge chamber and gas receiving vessel, described radio frequency wire surface scribbles insulating barrier and needle point is exposed, described radio frequency pin is a hollow, include air shooter, temperature sensor and radio frequency lead, the two ends of described temperature sensor and radio frequency lead link to each other with described control harvester with the tip of described radio frequency pin respectively, described air shooter links to each other with described gas container, in the described gas container gas is arranged, and have certain initial pressure.Adopt above-mentioned setting, can utilize gas and needle point to carry out heat exchange, make the needle surface temperature evenly preventing the generation of carbonization, thereby can be widely used in pathological tissues.

Description

The uniform radio-frequency ablation electrode of surface temperature
Technical field
The present invention relates to a kind of radio-frequency ablation electrode, relate in particular to a kind of radio-frequency ablation electrode that is used for oncotherapy.Utilize gas and needle point to carry out heat exchange, make the needle surface temperature even, prevent the radio-frequency ablation electrode of carbonization.
Background technology
Radio-frequency (RF) ablation has been widely used in treatment and has comprised multiple diseases such as liver's tumor, mastadenoma, prostate tumor and brain tumor.It is that the radio frequency pin is inserted pathological tissues that tumor is carried out radio-frequency (RF) ablation, negative plate or another electrode contact human body, the frequency electromagnetic waves of using the alternation that produces between the two makes the ion motion direction alternate in the tumor tissues, ion kinetic energy is converted to heat energy and causes the pathological tissues temperature to raise, thereby reaches therapeutic purposes.Direct heat melts effect and organizes the temperature correlation that is reached, and temperature is to be determined by the speed of the energy that applies, heating and the heat sensitivity of tissue.General heating-up temperature is 43 ℃-45 ℃, just can cause irreversible cell injury.Inactivation at this temperature range endoenzyme is the main factor that causes tissue injury.When tissue temperature was elevated to 60 ℃, the time that makes cell produce irreversible damage shortened greatly.After temperature raise and surpasses 60 ℃, protein denaturation in this temperature range, had and condenses between the necrotic area.When temperature continues to be elevated to 100 ℃ of left and right sides, moisture ebullition, gasification in the tissue.If temperature continues to raise, organize the phenomenon that carbonization then can take place and produce cigarette.In case carbonization produces, temperature can raise rapidly.Simultaneously, hinder the degree that tissue damaged hinders, and carbonization increased interstice's pressure, may cause cancerous cell diffusion and deeply tissue and blood vessel owing to thermal resistance restriction phenomenon having occurred.
In the middle of the operation of reality, owing to the relative position of radio frequency pin and negative plate can change along with the variation of the factors such as process of the different and operation technique of pathological tissues, this just makes the local radio frequency wire surface temperature height that electric current density is big, and the temperature height is easy to make the tissue that contacts with the radio frequency pin to form carbonization, cause radiofrequency ablation procedures not exclusively, even symptom such as massive hemorrhage can appear when electrode takes out.
Chinese invention patent is announced CN1263431C a kind of single needle water-cooled radio frequency ablating electrode is provided, supporting frame tight fit in the handle is inserted the water storage frame, intermediary cavity forms the cooling water backflow pool, radio-frequency (RF) ablation radio frequency pin leading portion scribbles insulation coating and is carved with yardstick, most advanced and sophisticated exposed, back segment inserts handle to be fixed on the water storage frame and to connect radio frequency leads, and built-in diversion steel pipe and inner temperature thermocouple thereof are inserted in the radio-frequency ablation electrode pin and keep coaxial position.Water supply hose is communicated with built-in diversion steel pipe, and delivery hose is communicated with the cooling water backflow pool, and radio frequency leads and thermocouple lead are formed special-purpose connection cord jointly, are connected with the main frame of radiofrequency ablation therapy system, finishes the signal transmission.Cooling water flows into by built-in diversion steel pipe from water supply hose and melts in the radio frequency pin, gets back to the cooling water backflow pool after heat exchange, flows back into recirculated cooling water device by delivery hose again.
Foregoing invention adopts solution (as water or saline) to carry out heat exchange at needle point, but because water inlet, the outlet conduit size is limited, cause solution flow rate slower, flow is little, when the electrode needle temperature is higher, flow resistance is bigger, causes heat exchange efficiency not high, thereby can not make radio frequency pin temperature evenly effectively prevent carbonization.
Summary of the invention
The purpose of this invention is to provide a kind of gas and needle point of utilizing and carry out heat exchange, make the needle surface temperature even, thereby can prevent the radio-frequency ablation electrode of carbonization.
For achieving the above object, the invention provides a kind of radio-frequency ablation electrode, it comprises radio frequency pin, control harvester, gas container, discharge chamber and gas receiving vessel, described radio frequency wire surface scribbles insulating barrier and needle point is exposed, described radio frequency pin is a hollow, include air shooter, temperature sensor and radio frequency lead, the two ends of described temperature sensor and radio frequency lead link to each other with described control harvester with the tip of described radio frequency pin respectively, described air shooter links to each other with described gas container, in the described gas container gas is arranged, and have certain initial pressure.
The further characteristics of radio-frequency ablation electrode of the present invention are: described needle point comprises needle point top and needle point bottom, also can contain two or more temperature sensors in the described radio frequency pin, one end of described two or more temperature sensors links to each other with described needle point bottom, and the other end links to each other with described control harvester.
The further characteristics of radio-frequency ablation electrode of the present invention are: described radio frequency lead and described most advanced and sophisticated welding.
The further characteristics of radio-frequency ablation electrode of the present invention are: described two or more temperature sensors are thermocouple sensor or thermal resistance sensor.
The further characteristics of radio-frequency ablation electrode of the present invention are: described two or more temperature sensors and described most advanced and sophisticated welding or thermo-contact.
The further characteristics of radio-frequency ablation electrode of the present invention are: described gas is air or nitrogen.
The further characteristics of radio-frequency ablation electrode of the present invention are: described needle point is made by rustless steel, Nitinol or titanium.
The further characteristics of radio-frequency ablation electrode of the present invention are: described radio-frequency ablation electrode also has handle, and itself and described radio frequency pin end fix.
The further characteristics of radio-frequency ablation electrode of the present invention are: described radio frequency pin cooperates fixing with described handle by fixture.
The further characteristics of radio-frequency ablation electrode of the present invention are: described handle is made by politef.
Utilize radio-frequency ablation electrode provided by the invention, gas flows out from gas container under the control of control harvester, arrive needle point by air shooter, when the needle region temperature too high, or needle point top and bottom temp be when inhomogeneous, gas can play strengthen heat exchange, make needle tip temperature at evenly, prevent that the high place of needle tip temperature at from the effect of carbonization taking place.Gas after the heat exchange flows out in the radio frequency pin, is discharged in the gas receiving vessel through discharge chamber.The temperature sensor that is installed in radio frequency pin needle point can be measured the temperature of radio frequency pin apex zone in real time, temperature signal can be in time by the collection of control harvester, simultaneously, the control harvester can be controlled in the generation of radiofrequency signal and the gas container gas purging and stop.
The present invention can make the needle surface temperature even owing to adopt technique scheme, preventing carbonization, thereby can be widely used in pathological tissues, and radio-frequency ablation electrode novel structure provided by the invention and compactness is safe in utilization.
Description of drawings
For clearlyer understanding the purpose of this utility model, characteristics and advantage, below with reference to accompanying drawing preferred embodiment of the present invention is described in detail, wherein:
Fig. 1 is the cutaway view of radio-frequency ablation electrode one preferred embodiment of the present invention.
The specific embodiment
As shown in Figure 1, the radio-frequency ablation electrode of a preferred embodiment of the present invention comprises radio frequency pin 1, handle 8, discharge chamber 10, gas receiving vessel 11, control harvester 12, gas container 13, radio frequency pin 1 is a hollow, the surface scribbles insulating barrier 2 and needle point 3 is exposed, needle point 3 comprises needle point top 14 and needle point bottom 15, comprises air shooter 4, temperature sensor 5 and 6, radio frequency lead 7 in the radio frequency pin 1.Handle 8 closely links to each other with radio frequency pin 1 by fixture 9.Air shooter 4 in the radio frequency pin 1 links to each other with gas container 13 through handle 8; Temperature sensor 5 in the radio frequency pin 1 and 6 and radio frequency lead 7 join with control harvester 12.
By shown in Figure 1, control harvester 12 is by the generation of radio frequency lead 7 control radiofrequency signals, corresponding tissue is melted, and the temperature sensor 6 at the temperature sensor 5 at 14 places, needle point top and 15 places, needle point bottom can be fed back the situation that melts to tissue, when both temperature difference are big, for example the temperature at temperature sensor 5 places raises when very fast, be easy to cause the carbonization of organizing that contacts with needle point top 14, generation for fear of this situation, gas can in needle point 3 places and wall generation heat exchange, reduce the needle point head temperature through air shooter 4 under the control of control harvester 12, make that needle point 3 surface temperatures are even, avoid the generation of carbonization phenomenon.
Wherein, needle point 3 is designed to pointed sealing, is convenient to insert pathological tissues.The back is a hollow circular cylinder, and its length and diameter adopt the mode of operation to decide by the size of wanting ablation tissue, the degree of depth that will insert tissue and doctor.Manufacture material and can use rustless steel, Nitinol or titanium etc.
In radio frequency pin 1 inside, radio frequency lead 7 joins with the tip, and method of attachment has a lot, waits other connected modes as welding.After control harvester 12 starts radiofrequency signal, produce the frequency electromagnetic waves of alternation between tip and the negative pole, this electromagnetic wave applies feasible organizationally tissue heating, and control harvester 12 control radio frequency generation power just can be controlled the heating state of tissue.
Radio frequency pin 1 most of zone except the tip all has insulating coating 2 to cover, and stops electric current to flow to surrounding tissue from the pin rear portion, therefore except the pin front end, does not heat with the contacted surrounding tissue in pin rear portion.Insulating barrier can change length, thereby variable ablation range is provided.
Used gas can be all gases in this invention, as air, nitrogen or other gas.These gas storage are in gas container 13, and gas container has certain initial pressure.
In needle point 3 inside, temperature sensor 5,6 can be joined by welding or other thermo-contact modes and tip.It can be thermocouple, thermal resistance or other forms of pick off.The temperature signal of the pin wall that is collected by it can reflect temperature of tissue surrounding, the degree that melts indirectly.
It should be noted that another preferred embodiment of the present invention also can only comprise in temperature sensor 5 or 6, feed back to control harvester 12, control gas purgings and stop by control harvester 12 again by its temperature signal that collects.In a preferred embodiment more of the present invention, also can comprise a plurality of temperature sensors, its function mode is identical with the temperature sensor 5 and 6 of present embodiment, does not repeat them here.
Handle 8 mainly plays connection and fixed effect.It is shaped as the cavity of a hollow, and radio frequency pin 1 terminal handle one end that inserts is tightly fixed under the effect of fixture 9.In addition, handle can be hand-held for the doctor, convenient operation.It can use materials such as politef.
It should be noted that another preferred embodiment of the present invention also can not comprise handle 8, and do not influence general idea of the present invention and spirit, have same technique effect.
Below preferred embodiment of the present invention is specified, but the present invention is not limited to described embodiment, those of ordinary skill in the art also can make all modification that is equal to or replacement under the prerequisite of spirit of the present invention, modification that these are equal to or replacement all are included in the application's claim institute restricted portion.

Claims (10)

1. radio-frequency ablation electrode comprises: the radio frequency pin, its be hollow and needle point exposed; It is characterized in that, also comprise control harvester, gas container, discharge chamber and gas receiving vessel; Described radio frequency wire surface scribbles insulating barrier, the hollow space of described radio frequency pin includes air shooter, temperature sensor and radio frequency lead, the two ends of described temperature sensor and radio frequency lead link to each other with described control harvester with the tip of described radio frequency pin respectively, described air shooter links to each other with described gas container, in the described gas container gas is arranged, and have certain initial pressure.
2. radio-frequency ablation electrode as claimed in claim 1 is characterized in that: described radio frequency pin contains two or more temperature sensors.
3. radio-frequency ablation electrode as claimed in claim 1 is characterized in that: described radio frequency lead and described most advanced and sophisticated welding.
4. radio-frequency ablation electrode as claimed in claim 1 or 2 is characterized in that: described temperature sensor is thermocouple sensor or thermal resistance sensor.
5. radio-frequency ablation electrode as claimed in claim 1 or 2 is characterized in that: described temperature sensor and described most advanced and sophisticated welding or thermo-contact.
6. radio-frequency ablation electrode as claimed in claim 1 is characterized in that: described gas is air or nitrogen.
7. radio-frequency ablation electrode as claimed in claim 1 is characterized in that: described needle point is most advanced and sophisticated to be sealed, and is made by rustless steel, Nitinol or titanium.
8. radio-frequency ablation electrode as claimed in claim 1 is characterized in that: described radio-frequency ablation electrode also has handle, and itself and described radio frequency pin end fix.
9. radio-frequency ablation electrode as claimed in claim 8 is characterized in that: described radio frequency pin cooperates fixing with described handle by fixture.
10. radio-frequency ablation electrode as claimed in claim 8 is characterized in that: described handle is made by politef.
CNA2007100472638A 2007-10-19 2007-10-19 The uniform radio-frequency ablation electrode of surface temperature Pending CN101411645A (en)

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102028538A (en) * 2011-01-24 2011-04-27 苗毅 Multifunctional cold circulation concentrated beam radiofrequency treatment probe
CN101919730B (en) * 2009-06-12 2012-01-25 王兴林 Ablating electrode
CN102579130A (en) * 2012-03-12 2012-07-18 北京恒福思特科技发展有限责任公司 Thermosetting needle
CN102824214A (en) * 2012-09-11 2012-12-19 邹英华 Radio frequency conduit capable of fully closing blood vessel and radio frequency instrument thereof
CN103565512A (en) * 2012-07-26 2014-02-12 乐普(北京)医疗器械股份有限公司 Radiofrequency ablation catheter for renal arteries
WO2014026470A1 (en) * 2012-08-16 2014-02-20 珠海市司迈科技有限公司 Bipolar electrode for resectoscope
CN103784193A (en) * 2014-03-05 2014-05-14 上海导向医疗系统有限公司 Cold knife used for tumour cryoablation
CN105266895A (en) * 2015-09-07 2016-01-27 倪家骧 Plasma radio frequency ablation puncture trocar composite set composite set
CN106618731A (en) * 2009-11-11 2017-05-10 赫莱拉公司 Systems, apparatuses, and methods for treating tissue and controlling stenosis
CN107753098A (en) * 2011-04-12 2018-03-06 热医学公司 Method and apparatus for controlling ablation
CN107981928A (en) * 2017-12-06 2018-05-04 北京博海康源医疗器械有限公司 A kind of ablating electrode temperature control equipment and its ablating electrode temprature control method
CN108066003A (en) * 2017-12-29 2018-05-25 浙江归创医疗器械有限公司 Ablation catheter
CN114259294A (en) * 2018-09-14 2022-04-01 杭州堃博生物科技有限公司 Radiofrequency ablation catheter, pulmonary radiofrequency ablation system and corresponding control method
US11918277B2 (en) 2018-07-16 2024-03-05 Thermedical, Inc. Inferred maximum temperature monitoring for irrigated ablation therapy
US11937868B2 (en) 2008-05-09 2024-03-26 Nuvaira, Inc. Systems, assemblies, and methods for treating a bronchial tree

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11937868B2 (en) 2008-05-09 2024-03-26 Nuvaira, Inc. Systems, assemblies, and methods for treating a bronchial tree
CN101919730B (en) * 2009-06-12 2012-01-25 王兴林 Ablating electrode
US11389233B2 (en) 2009-11-11 2022-07-19 Nuvaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US10363091B2 (en) 2009-11-11 2019-07-30 Nuvaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
CN106618731A (en) * 2009-11-11 2017-05-10 赫莱拉公司 Systems, apparatuses, and methods for treating tissue and controlling stenosis
CN102028538B (en) * 2011-01-24 2012-07-11 苗毅 Multifunctional cold circulation concentrated beam radiofrequency treatment probe
CN102028538A (en) * 2011-01-24 2011-04-27 苗毅 Multifunctional cold circulation concentrated beam radiofrequency treatment probe
CN107753098A (en) * 2011-04-12 2018-03-06 热医学公司 Method and apparatus for controlling ablation
US11950829B2 (en) 2011-04-12 2024-04-09 Thermedical, Inc. Methods and devices for use of degassed fluids with fluid enhanced ablation devices
US11871979B2 (en) 2011-04-12 2024-01-16 Thermedical, Inc. Methods and devices for controlling ablation therapy
CN102579130A (en) * 2012-03-12 2012-07-18 北京恒福思特科技发展有限责任公司 Thermosetting needle
CN103565512A (en) * 2012-07-26 2014-02-12 乐普(北京)医疗器械股份有限公司 Radiofrequency ablation catheter for renal arteries
WO2014026470A1 (en) * 2012-08-16 2014-02-20 珠海市司迈科技有限公司 Bipolar electrode for resectoscope
CN102824214A (en) * 2012-09-11 2012-12-19 邹英华 Radio frequency conduit capable of fully closing blood vessel and radio frequency instrument thereof
CN103784193B (en) * 2014-03-05 2015-12-02 上海导向医疗系统有限公司 Tumor cryoablation cryoprobe
CN103784193A (en) * 2014-03-05 2014-05-14 上海导向医疗系统有限公司 Cold knife used for tumour cryoablation
CN105266895A (en) * 2015-09-07 2016-01-27 倪家骧 Plasma radio frequency ablation puncture trocar composite set composite set
CN107981928A (en) * 2017-12-06 2018-05-04 北京博海康源医疗器械有限公司 A kind of ablating electrode temperature control equipment and its ablating electrode temprature control method
CN108066003A (en) * 2017-12-29 2018-05-25 浙江归创医疗器械有限公司 Ablation catheter
US11918277B2 (en) 2018-07-16 2024-03-05 Thermedical, Inc. Inferred maximum temperature monitoring for irrigated ablation therapy
CN114259294A (en) * 2018-09-14 2022-04-01 杭州堃博生物科技有限公司 Radiofrequency ablation catheter, pulmonary radiofrequency ablation system and corresponding control method

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