CN101392075B - Formula for synthesizing rubber injection member for disposable infusion device and method for producing the same - Google Patents
Formula for synthesizing rubber injection member for disposable infusion device and method for producing the same Download PDFInfo
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- CN101392075B CN101392075B CN2007101320825A CN200710132082A CN101392075B CN 101392075 B CN101392075 B CN 101392075B CN 2007101320825 A CN2007101320825 A CN 2007101320825A CN 200710132082 A CN200710132082 A CN 200710132082A CN 101392075 B CN101392075 B CN 101392075B
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Abstract
The invention discloses a formula of a synthetic rubber injection element used by a disposable infusion set. Main elements thereof comprise the following components (expressed by wt. percent): 48 percent to 58 percent of isoprene synthetic rubber, 1 percent to 2.5 percent of titanium pigment, 4.5 percent to 5.5 percent of zinc carbonate, 13 percent to 20 percent of stearic acid, 13 percent to 20 percent of 4-thio-bis(1, 5-pentylidene) thiuram, 3 percent to 5 percent of N-cyclohexyl-2-benzothiazole sulfonamide and 3 percent to 5 percent of glycerin. A production method thereof comprises the following working procedures sequentially: preparation of raw materials, drying, plastication and mixing, inspection and placement, refinement and tablet production, vulcanization for shaping, inspection, blanking, washing and drying and packaging for storage. By adopting the formula, sulfur is not used as a vulcanizing agent, thereby greatly reducing the pollution to the environment. Compared with dry rubber products of nature rubber, the subsequent working procedures are greatly simplified and a cooking procedure lasting for a plurality of hours is saved, thus substantially reducing resource consumption.
Description
Technical field
The present invention relates to a kind of medicine equipment.Specifically, be about prescription and the production method thereof of a kind of disposable transfusion (blood) device with synthesizing rubber injection member.
Background technology
Along with the medical apparatus industry development, the invention of disposable medical appliance is maked rapid progress.As disposable transfusion (blood) device synthesizing rubber injection member, initial external this product of producing is to use latex mostly, but latex product is easily aging, and the life-span is short.And after aging, can cause small number of patients generation heat source response; The production of this product both at home and abroad now replaces latex with the dried glue of natural rubber, and the product of this material has puncture property, good airproof performance, and ageing-resistant performance, physical and mechanical properties, chemical property, biological assessment etc. all are significantly improved.But U.S. medical circle Ceng You expert proposes: have several ten thousand approximately/ the patient, to the protease-producing anaphylaxis that contains in disposable infusion (blood) the device synthesizing rubber injection member.Thus, the organic protein that contains in this product is defined as objectionable impurities.Therefore to remove the organic protein that contains in this product, must carry out special process to the dried glue of natural rubber and handle, this product be carried out surface modification carry out harmless treatment.Produce too high technology cost thus and make enterprise be difficult to bear, be difficult to drop into commercial scale production and use.
This has proposed a new problem that how to solve harmful organic problem in this product to the enterprise that China produces this product.
Summary of the invention
At above deficiency, the object of the present invention is to provide a kind of with dried glue making disposable transfusion device injection member of isoprene synthetic rubber replacement natural rubber and production method thereof.Make the existing good puncture of disposable transfusion device, stopping property, good aging properties, physical and mechanical properties and chemical property do not contain organic protein again, and have superior Biosafety performance, also have good economic.
Technical scheme of the present invention realizes in the following manner:
The prescription of synthesizing rubber injection member for disposable infusion device, its major ingredient comprises following component (representing with wt.%): isoprene synthetic rubber 48-58%, titanium dioxide 1-2.5%, zinc carbonate 4.5-5.5%, hard fatty acids 13-20%, two (pentamethylene) thiuram 13-20% of tetrathio, N cyclohexyl 2 benzothiazole sulfenamide 3-5%, glycerine 3-5%.
The production method of synthesizing rubber injection member for disposable infusion device comprises following operation successively: starting material prepare, dry, plasticate mixing, check is parked, refining slice, vulcanization forming, check, stamping-out, washing drying, packing warehouse-in; It is characterized in that:
1) in the described vulcanization forming operation, be vulcanizing agent, promotor, with two (pentamethylene) thiurams of tetrathio.
In the above-mentioned vulcanization forming operation, pressure: 20Mpa, temperature: 160 ℃～165 ℃, time: 240s～250s.
2), in the described washing drying process, washing is carried out in 100,000 grades of dust proof workshops.
Above-mentioned washings configuration proportion is: 1000 parts of waters for injection, normal temperature; 1 part of NaOH.
Above-mentioned washing drying is in scavenging solution after the rinsing three times, dewatered drying.
The present invention does not contain organic albumen through the biological property analysis discovery isoprene synthetic rubber to multiple synthetical glue, and different oxide content is lower.Compare with other synthetic rubber (as silicon rubber, viton) etc., the isoprene processing performance is good, and the present invention is vulcanizing agent, promotor with DPTT (two (pentamethylene) thiurams of tetrathio), do not use sulphur to make vulcanizing agent, to the yet greatly reduction of pollution of environment.This product is compared with the dried glue product of natural rubber, and later process simplifies greatly, has exempted the boiling that reaches a few hours, and resource consumption reduces significantly.
Embodiment
Embodiment 1: the prescription of synthesizing rubber injection member for disposable infusion device, its major ingredient comprises following component (representing with wt.%): isoprene synthetic rubber 48%, titanium dioxide 2%, zinc carbonate 5.5%, hard fatty acids 18%, two (pentamethylene) thiurams 18% of tetrathio, N cyclohexyl 2 benzothiazole sulfenamide 3.5%, glycerine 5%.
Embodiment 2: the prescription of synthesizing rubber injection member for disposable infusion device, its major ingredient comprises following component (representing with wt.%): isoprene synthetic rubber 56%, titanium dioxide 1.5%, zinc carbonate 4.5%, hard fatty acids 15%, two (pentamethylene) thiurams 15% of tetrathio, N cyclohexyl 2 benzothiazole sulfenamide 4%, glycerine 4%.
The production method of the foregoing description is followed successively by: starting material prepare, dry, plasticate mixing, check is parked, refining slice, vulcanization forming, check, stamping-out, washing drying, packing warehouse-in.Wherein: in the described vulcanization forming operation, be vulcanizing agent, promotor with two (pentamethylene) thiurams of tetrathio.The present invention vulcanizes three elements:
Pressure: 20Mpa
Temperature: 160 ℃～165 ℃
Time: 240s～250s
In the described washing drying process, washing is carried out in 100,000 grades of dust proof workshops, and the product washing is carried out in 100,000 grades of dust proof workshops, and the washings configuration proportion is:
1000 parts of waters for injection, normal temperature.
1 part of NaOH.
In scavenging solution after the rinsing three times, dewatered drying.
This product is compared with the dried glue product of natural rubber, and later process simplifies greatly, has exempted the boiling that reaches a few hours, and resource consumption reduces significantly.This product substitutes sulphur as vulcanizing agent and promotor with DPTT, to the also greatly reduction of pollution of environment.The present invention meets fully that country is energy-saving and cost-reducing, the requirement of environmental protection strategic objective.
Product of the present invention, its the key technical indexes reaches GB 8368-1998, GB 8369-1998 and ISO 8536-4:1998, ISO 1135-4:1998 standard-required, the no collodion silk in surface, buffings, impurity and bloom, no steam bubble, starved, slight crack, cut damage, off-centre, color and luster is even, selfsealings: the spillage of water is no more than one.
Claims (5)
1. the composition that is used for synthesizing rubber injection member for disposable infusion device, its major ingredient comprises following component, represents with wt%: isoprene synthetic rubber 48-58%, titanium dioxide 1-2.5%, zinc carbonate 4.5-5.5%, hard fatty acids 13-20%, two (pentamethylene) thiuram 13-20% of tetrathio, N cyclohexyl 2 benzothiazole sulfenamide 3-5%, glycerine 3-5%.
2. the production method of preparation of compositions synthesizing rubber injection member for disposable infusion device according to claim 1 comprises following operation successively: starting material prepare, dry, plasticate mixing, check is parked, refining slice, vulcanization forming, check, stamping-out, washing drying, packing warehouse-in; It is characterized in that:
1) in the described vulcanization forming operation, be vulcanizing agent, promotor, with two (pentamethylene) thiurams of tetrathio;
2), in the described washing drying process, washing is carried out in 100,000 grades of dust proof workshops, in the above-mentioned vulcanization forming operation, pressure: 20Mpa, temperature: 160 ℃～165 ℃, time: 240s～250s.
3. the production method of preparation synthesizing rubber injection member for disposable infusion device according to claim 2 is characterized in that: in the described vulcanization forming operation, and pressure: 20Mpa, temperature: 160 ℃～165 ℃, time: 240s～250s.
4. the production method of preparation synthesizing rubber injection member for disposable infusion device according to claim 2 is characterized in that: described washings configuration proportion is: 1000 parts of waters for injection, normal temperature; 1 part of NaOH.
5. the production method of preparation synthesizing rubber injection member for disposable infusion device according to claim 2 is characterized in that: described washing drying process is in scavenging solution after the rinsing three times, dewatered drying.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101320825A CN101392075B (en) | 2007-09-21 | 2007-09-21 | Formula for synthesizing rubber injection member for disposable infusion device and method for producing the same |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101320825A CN101392075B (en) | 2007-09-21 | 2007-09-21 | Formula for synthesizing rubber injection member for disposable infusion device and method for producing the same |
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| Publication Number | Publication Date |
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| CN101392075A CN101392075A (en) | 2009-03-25 |
| CN101392075B true CN101392075B (en) | 2010-08-25 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102585310B (en) * | 2011-12-27 | 2014-04-30 | 崇州君健塑胶有限公司 | Medical sealing gasket and preparation method thereof |
| CN104140570B (en) * | 2014-07-14 | 2016-08-17 | 丹阳市金晟医用橡塑制品有限公司 | A kind of disposable blood sampling needle tip shield and manufacture method thereof |
| CN107349486A (en) * | 2017-06-28 | 2017-11-17 | 安徽光大医疗科技股份有限公司 | A kind of biliquid is the same as defeated type disposable transfusion device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001094461A1 (en) * | 2000-06-08 | 2001-12-13 | Uniroyal Chemical Company, Inc. | Rubber compositions and method for increasing the mooney scorch value |
| CN1699456A (en) * | 2004-05-20 | 2005-11-23 | HenkelHongseong株式会社 | Foaming sheet composition for reducing vehicle noise and method for making same |
| CN1730525A (en) * | 2005-08-16 | 2006-02-08 | 上海工程技术大学 | Microcapsulized expansion type flame-proof rubber and its preparation method |
-
2007
- 2007-09-21 CN CN2007101320825A patent/CN101392075B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001094461A1 (en) * | 2000-06-08 | 2001-12-13 | Uniroyal Chemical Company, Inc. | Rubber compositions and method for increasing the mooney scorch value |
| CN1699456A (en) * | 2004-05-20 | 2005-11-23 | HenkelHongseong株式会社 | Foaming sheet composition for reducing vehicle noise and method for making same |
| CN1730525A (en) * | 2005-08-16 | 2006-02-08 | 上海工程技术大学 | Microcapsulized expansion type flame-proof rubber and its preparation method |
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| CN101392075A (en) | 2009-03-25 |
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