CN101390569A - Use of nano zinc oxide in baby pig feedstuff - Google Patents
Use of nano zinc oxide in baby pig feedstuff Download PDFInfo
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- CN101390569A CN101390569A CNA2007100551748A CN200710055174A CN101390569A CN 101390569 A CN101390569 A CN 101390569A CN A2007100551748 A CNA2007100551748 A CN A2007100551748A CN 200710055174 A CN200710055174 A CN 200710055174A CN 101390569 A CN101390569 A CN 101390569A
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Abstract
The invention relates to the application of nano-zinc oxide in piglet feed, wherein, the particle size of the nano-zinc oxide is less than 50nm. In the invention, the nano-zinc oxide has antibacterial and growth-promoting effects; in the feed for early weaned piglets, the nano-zinc oxide with less than 50nm of physical size has significant positive effect of nutritional physiology. 50 - 100ppm of low-dose added nano-zinc oxide can obviously improve the piglet production performance and save the zinc source in the post-test and the entire test period. The invention uses the nano-zinc oxide with the particle size less than 50nm to replace the ordinary zinc oxide in the piglet feed, wherein, 100-300 grams/ton of the nano-zinc oxide with the particle size less than 50nm can replace 3000 grams/ton of ordinary zinc oxide and can achieve the same effect, so as to reduce the adding amount of ordinary zinc oxide and greatly decrease the production cost; therefore, the nano-zinc oxide has very good social value and economic value and is easy to promote.
Description
Technical field
The present invention relates to the application of a kind of nano zine oxide in baby pig feedstuff.
Background technology
Since Todd in 1934 studies have shown that for the first time zinc is essential trace element (Todd1934) in the rat growth, a large amount of scientific researches showed that zinc is animal survival, growth and the essential trace element of producing animal product, has important nutrition physiology effect.The beginning of the eighties, and zinc finger protein (zinc fingerproteins, discovery ZFPs) and studies show that subsequently: zinc also has crucial effect (Chothia, 1992 to inhereditary material; Shi, 1995; Berg, 1996), zinc content is key factor (Lepage, 1999 that influence gene expression; Kindermann 2004).(2000-3000mg/kg) studies show that can reduce the grice diarrhoea rate to high dose zinc oxide, improves the production achievement, but also brought problems such as the waste in non-renewable zinc source and environmental pollution.Therefore the Studies on Nutritional and Physiological Effects of zinc is the hot subject of Animal nutrition and forage science research always.
Though the somatotrophic mechanism of high dose zinc oxide is also unclear at present, but the existing high dose zinc oxide that studies show that has the growth effect of special promotion animal and reduces the effect of suffering from diarrhoea for early-weaned piglets, and organic zinc and zinc sulfate can not play the growth promotion effect of high dose zinc oxide, therefore seek zinc source efficiently, make its maintenance have the reduction diarrhea rate and the growth enhancing effect of zinc oxide, can save non-renewable zinc source again and reduce environmental pollution, this is the hot subject of Animal nutrition research and feed industry, Chemical Manufacture research always.Can replace present conventional zinc source of using by new results, the new product of nanosecond science and technology in breeding production, this be new opportunities and challenges, also is new approaches.
Nano zine oxide is a kind of novel zinc source, commercially produce at present, the market share of nano-metal-oxide such as nano zine oxide and nano metal has reached annual 7.5 hundred million Euros (BCC 2004), be mainly used in high added value industries such as cosmetics, rubber, clothes, food fresh keeping, the application result that does not have safety evaluation from cosmetics shows: nano zine oxide is safe (SCCNFP 2003, and FDA 1999).The absorption of zinc and utilization depend primarily on zinc source form (Lowe 1996, Fairweather-Tait1993, square Lip river cloud 2001), and the particle size of nutriment is to influence the key that it absorbs.
Summary of the invention
The object of the present invention is to provide the application of a kind of nano zine oxide in baby pig feedstuff, to reduce cost.
To achieve these goals, technical program of the present invention lies in adopting the application of a kind of nano zine oxide in baby pig feedstuff.
The particle diameter of described nano zine oxide is less than 50nm.
The particle diameter of described nano zine oxide is 30-50nm.
In later stage and full phase feeding piglet, the addition of nano zine oxide is 50-100ppm.
Nano zine oxide has antibiotic somatotrophic effect in the present invention, and in the early-weaned piglets material, physical size has obvious nutrient physiology positive-effect less than the nano zine oxide of 50nm.The nano zine oxide that 50-100ppm low dosage adds has the tangible effect that improves piglet production achievement and save the zinc source in test later stage and full phase of test.The present invention adopts particle diameter less than the common zinc oxide in the alternative baby pig feedstuff of the nano zine oxide of 50nm, 100-300 gram/tons substitute the common zinc oxide of 3000 gram/tons less than the nano zine oxide of 50nm, not only reach same effect, reduced the addition of common zinc oxide simultaneously, greatly reduce production cost, have favorable social and economic worth, be easy to apply.
The specific embodiment
The particle diameter of the nano zine oxide of present embodiment is less than 50nm.
The different-grain diameter nano zine oxide is to the influence of breeding performonce fo animals
1. average 100nm zinc oxide under normal zink rod spare to the influence of piglet production performance
1.1 materials and methods
1.1.1 material and design
Mixed oxidization zinc: average 100nm, wherein Zn content is 77.32%.
Feed grade zinc oxide and zinc sulfate.
Adopt single factor experiment design (as table 1).Select blood relationship, age in days, 18 head lengths that body weight is close white * too weanling pig is assigned randomly to 3 processing, each handles 3 repetitions, each repeats 2 pigs.3 weeks of experimental period.
Table 1
Annotate: the addition of Different Zinc Source was the zinc content after amounting to during each was handled, below each epiphase with.
1.1.2 diet preparation
Trophic level is with reference to NRC (1998) swine rearing standard recommendation parameter, consider the piglet digestive physiology, with corn, dregs of beans, expanded soybean, whole milk powder and fish meal etc. are formed basic diet, add the zinc salt in various dose and source by experimental design in basic diet then, and the physical aspect of diet is a powder.
Table 2 Screening Experiment of Diet and trophic level
Table2. Ingredients?and?Nutrient?level?of?basal?diet
Annotate: the used multidimensional of (1) test daily ration is produced by feed corporation,Ltd of Sichuan poultry section, and every kg contains VitA54, and 000,000IU, VitD
3108,000,000IU, VitE 18,000IU, Vitk
35g, VitB
12g, VitB
215g, VitB
66g, VitB
1230mg, nicotinic acid 35g, calcium pantothenate 25g, folic acid 500mg; (2) the basic diet of every kg contains Fe 100mg, and Cu 6mg, Mn 4mg, Se0.3mg, I 0.14mg., (3) DM are that 87.6% (4) every kg basis diet contains Zn 19.04mg
1.1.3 feeding and management
Test is carried out at commercial city group test site.Rinse the pig cage well with clear water before the test, with buck (2% NaOH) and hundred poisonings pig cage and colony house are sterilized, last airtight door and window is to colony house fumigation (every cubic metre restrains potassium permanganate with 25ml formaldehyde and 25 and adds water 12.5ml, stifling 24 hours).
Piglet 25-28 ages in days adopt sow to be with young basestocks to lure and raise; Piglet changes in the test pig house in 28 ages in days, and 2 piglets of each pig cage freely drink water and free choice feeding, is degree to show a small surplus after having enough at every turn.Adopt the infrared lamp insulation in the house, make room temperature remain on 26-28 ℃, and keep sanitation and hygiene and circulation of air in the pig house, regularly sterilization.Duration of test examines the situation of searching for food and the mental status of piglet every day, and record feed intake and clout are heavy.
1.1.4 testing index
1.1.4.1 production performance index
1. average daily gain (ADG): piglet is calculated daily gain in testing weekly single the weighing of 8:00 empty stomach in morning last day;
2. average daily ingestion amount (ADFI): for unit settles accounts feed intake every day, calculate each stage A DFI with the circle;
3. feedstuff-meat ratio (F/G): calculate F/G according to daily gain and daily ingestion amount.
1.2 result of the test
Average 100nm mixed oxidization zinc, zinc sulfate and feed grade zinc oxide the results are shown in following table to the influence of piglet production performance:
The average 100nm zinc oxide of table 3. is to the influence of the full phase production performance of piglet
The average 100nm zinc of Table3.Effects of oxide on performance of piglets in whole period
Annotate: allly indicate the identical lowercase or the expression difference not significantly (p〉0.05) of mark letter shoulder number, lowercase shoulder different table differential different remarkable (p＜0.05) with the line data upper right corner; If institute's target capitalization is all different with lowercase, then represent difference extremely significantly (p＜0.01); Below each table remove have special dated, the significance test result represents that note is identical therewith.
Result of the test shows: test between each processed group piglet production performance difference not significantly (P〉0.05), zinc sulfate group end weight, average daily gain, feed intake and feedstuff-meat ratio all are higher than average 100nm nano zine oxide and feed grade zinc oxide group (P〉0.05), but average 100nm nano zine oxide is compared the average daily gain of piglet and is improved 1.2% with feed grade zinc oxide, feed intake improves 8.2%.Show the production performance effect of being significantly improved of reducing of zinc oxide particle diameter to piglet.
Under the high zink rod spare of the zinc oxide of 30-50nm to the influence of piglet production performance
2.1 materials and methods
2.1.1 test material and design
The nano zine oxide of 30-50nm, feed grade zinc oxide.
Experimental design adopts the single factor experiment design, selects blood relationship, age in days, body weight is close, and 18 head lengths * too weanling pig is assigned randomly to 3 processing, and each handles 3 repetitions, and each repeats 2 pigs, 4 weeks of experimental period.
Table 4. experimental design
Table?4.Experiment?design
2.1.2 diet preparation
The test daily ration is formed and trophic level test one together.
2.1.3 feeding and management
Be same as test one.
2.1.4 test index
Test one together finishes back 8:00 in morning next day empty stomach individuality weekly in test and weighs, and the statistics feed consumption rate, calculates average daily gain, feed intake, feedstuff-meat ratio.
2.1.5 data are handled
With test one
2.2 result of the test
The nano zine oxide of 30-50nm is to the influence (seeing Table 5) of the full phase production performance of piglet
Table 5 30-50nm nano zine oxide is to the influence of the full phase production performance of piglet
Table?5.Effects?of?30—50nm?nano-zinc?oxide?on?performance?of?piglets?in whole?period
Annotate: indicate different capitalizations with the data line shoulder and represent difference extremely significantly (P＜0.01), indicate different lowercase alphabet differentials different significantly (P＜0.05); Otherwise, then represent difference not significantly (P〉0.05).
The production achievement of adding 2000mg/kg nano-ZnO group raising piglet is the highest, wherein daily gain is significantly higher than feed grade zinc oxide 3000mg/kg group (p＜0.05), and the nano zine oxide of high dose and feed grade zinc oxide group feed intake all are higher than the nano zine oxide group of 100mg/kg.The daily gain of the nano zine oxide group of 100mg/kg and feed efficiency all are better than the feed grade zinc oxide (p〉0.05) of 3000mg/kg.
Show the nano zine oxide of high dose and the effect that feed grade zinc oxide has obvious raising feed intake, use the nano zine oxide of low additive capacity testing the full phase is better than 3000mg/kg to the growth promotion effect of piglet feed grade zinc oxide.
Experimental result
Experimental result shows: average 100nm nano zine oxide raising piglet production achievement is lower than zinc sulfate but is higher than feed grade zinc oxide, each processed group difference is not remarkable, compare with feed grade zinc oxide, the mixed oxidization zinc of average 100nm is higher than its growth enhancing effect to the improvement of nutrition physiology effect.
The growth enhancing effect of the nano zine oxide of 30-50nm is higher than feed grade zinc oxide, the 2000mg/kg nano zine oxide improves the feed grade zinc oxide (p＜0.05) that daily gain is significantly higher than 3000mg/kg, the feed grade zinc oxide that the nano zine oxide group piglet daily gain of 100mg/kg and feed efficiency are better than 3000mg/kg (p〉0.05).The physical size of zinc oxide varies in size, its growth enhancing effect difference, and physical size is more little, and biologically active is high more, and the growth promotion effect is good more.
It should be noted last that: above embodiment is the unrestricted technical scheme of the present invention in order to explanation only, although the present invention is had been described in detail with reference to the foregoing description, those of ordinary skill in the art is to be understood that: still can make amendment or be equal to replacement the present invention, and not breaking away from any modification or partial replacement of the spirit and scope of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (4)
1, the application of a kind of nano zine oxide in baby pig feedstuff.
2, the application of nano zine oxide according to claim 1 in baby pig feedstuff is characterized in that: the particle diameter of described nano zine oxide is less than 50nm.
3, the application of nano zine oxide according to claim 2 in baby pig feedstuff is characterized in that: the particle diameter of described nano zine oxide is 30-50nm.
4, according to arbitrary the application of described nano zine oxide in baby pig feedstuff in the claim 1-3, it is characterized in that: in later stage and full phase feeding piglet, the addition of nano zine oxide is 50-100ppm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100551748A CN101390569A (en) | 2007-09-17 | 2007-09-17 | Use of nano zinc oxide in baby pig feedstuff |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100551748A CN101390569A (en) | 2007-09-17 | 2007-09-17 | Use of nano zinc oxide in baby pig feedstuff |
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| Publication Number | Publication Date |
|---|---|
| CN101390569A true CN101390569A (en) | 2009-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100551748A Pending CN101390569A (en) | 2007-09-17 | 2007-09-17 | Use of nano zinc oxide in baby pig feedstuff |
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|---|---|
| CN (1) | CN101390569A (en) |
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2007
- 2007-09-17 CN CNA2007100551748A patent/CN101390569A/en active Pending
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