CN101380337B

CN101380337B - Low temperature dynamic extraction method of plant effective ingredient

Info

Publication number: CN101380337B
Application number: CN2008100882853A
Authority: CN
Inventors: 张国荣
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-04-30
Filing date: 2008-04-30
Publication date: 2012-05-23
Anticipated expiration: 2028-04-30
Also published as: CN101380337A

Abstract

A low-temperature dynamic extraction method of plant active ingredients is completed by selecting materials, cleaning, drying, smashing, infiltrating, dynamic extracting, separating and concentrating. The method is characterized in that: a plant is smashed into powder and sent to an extraction tank for separating after the infiltration, solid-liquid mixture after the separation is re-sent to the extraction tank for extracting for a second time after the microwave radiation. The extraction of the plant active ingredients of the method is more thorough and has high efficiency and significant effect.

Description

A kind of low temperature is made the method for extracting effective ingredients in plant

Technical field

The method, the especially low temperature that the present invention relates to the plant material composition extraction of a kind of Chinese patent medicine, health product, food etc. are made the method for extracting active ingredients of plants.

Background technology

The method that with water is the total active ingredient of solvent extraction plant at present is a decocting method, and extraction must be boiled and carried out, and the time is longer, most Chinese patent medicine quality standard regulations " decocting boiled 3 hours for the first time, and 2 hours for the second time, 1 hour for the third time ".Also have and have only precedingly twice, this method energy resource consumption is big, and production efficiency is low, and particularly high temperature for a long time makes the total active ingredient loss of plant more, and the target product quality descends.The technology of now can efficient cryogenic extracting active ingredients of plants is CO ₂The supercritical extraction method, it belongs to high pressure technique (usually more than 7090kpa), and the technical process specification requirement is high, the equipment investment expense is bigger, is difficult to popularize.In the said extracted method, be graininess when plant feeds intake, adopt Powdered extraction method also not appear in the newspapers.

Summary of the invention

The purpose of this invention is to provide a kind of be solvent low temperature with water, extract the method for active ingredients of plants efficiently.

Technical scheme of the present invention is: to raw material select materials, that mechanical activation comminution is carried out in cleaning, exsiccant common process after accomplishing is powdered, particle size range 20～80 orders, the back water that breaks that plant cell wall is acquired a certain degree soaks into and makes the further swelling breaking cellular wall of material; Let the easy stripping of active ingredient in the plant, make extraction then, send in the extraction pot; Under state after compressed air promotion or the mechanical agitation; Active ingredient is got in the solvent, liquid is separated out and concentrate through separator, it is more than 50% that the solid-liquid mixture of residual powder shape is also answered moisture; The material of the solid-liquid mixture in the entering microwave box is thick to be 2.5 centimetres; Microwave adopts 2450MHz, and radiated time is 2-9 minute, sends back to once more after the radiation and carries out second time extraction, separation, concentration process in the extraction pot.Through radiation effects, make the further breaking cellular wall of material, active ingredient gets in the solvent more easily, and radiation has great role to improving extraction active ingredient ratio.This method also is applicable to organic solvent extraction commonly used.

The invention has the beneficial effects as follows: to the active ingredient of plant extract more thorough; With water for solvent economy is easy to get, safe and reliable, non-pollution discharge, be easy to promote; Extract and carry out to make thermo-labile in the plant, volatile active ingredient to obtain maximum reservation at low temperatures, improved the quality of extracting product, shortened extraction time; Improved efficient, remarkable in economical benefits.

The specific embodiment

Instance 1: get 40 order red ginseng powders, 200 grams, content of ginsenoside is 6.58%, ginseng, water ratio 1: 3; Soak into and send into extraction pot after 3 hours, make 60 ℃ of first time and extracted 40 minutes, separation of material moisture 50～60% gets into microwave radiation; Microwave 2450MHz expects thick 2.5 centimetres, and extraction pot is sent in radiation once more after 3 minutes; Make extraction 30 minutes 60 ℃ of second time; 70 grams that after separating back merging filtrate concentrate drying, get dry extract, recording the total soap content of Radix Ginseng is 16.54%, the extraction ratio of calculating active ingredient is 87.99%.

Instance 2: get Folium Caryophylli material (20 order) 200 gram, record content protocatechuic acid 1.8%, sent into 60 ℃ of extraction pot in 2 hours with 20 times of water infiltrations and make extraction filtration after 20 minutes, again through microwave radiation 3 minutes; Expect thick 2.5 centimetres, microwave 2450MHz sends into extraction pot once more, 60 ℃; 15 times of water are made filtration in 20 minutes, 70 grams that get dry extract after the merging filtration drying, residue 125 grams; Through detecting, dried cream protocatechuic acid content is 4.61%, and the former a few boheic acid content of residue are 0.18%; Active ingredient extraction ratio 89.64% is compared with traditional extraction method and (is got Folium Caryophylli leaf 200 grams, extract 74 grams that get dry extract with the traditional decoction method; Contain protocatechuic acid 3.06%, residue contains protocatechuic acid 0.58%, and extraction ratio is 67.70%) active ingredient significantly improves.

Claims

1. a low temperature is made the method for extracting effective ingredients in plant, it is characterized in that: get 40 order red ginseng powders, 200 grams, content of ginsenoside is 6.58%; Ginseng, water ratio 1: 3 are soaked into and are sent into extraction pot after 3 hours, make 60 ℃ of first time and extract 40 minutes; Separation of material moisture 50～60% gets into microwave radiation, and microwave 2450MHz expects thick 2.5 centimetres; Extraction pot is sent in radiation once more after 3 minutes, make 60 ℃ of second time and extracted 30 minutes, and 70 grams get dry extract behind the merging filtrate concentrate drying after separating; Record Radix Ginseng total saponins content 16.54%, calculating extraction ratio of effective constituents is 87.99%.

2. a low temperature is made the method for extracting effective ingredients in plant, it is characterized in that: get 20 order Folium Caryophylli material, 200 grams, record content protocatechuic acid 1.8%; Send into 60 ℃ of extraction pot in 2 hours with 20 times of water infiltrations and make and extract 20 minutes after-filtration, through microwave radiation 3 minutes, expect thick 2.5 centimetres again; Microwave 2450MHz sends into extraction pot once more, 60 ℃; 15 times of water are made and are extracted 20 minutes after-filtration, 70 grams that get dry extract behind the merging filtrate concentrate drying, residue 125 grams; The survey protocatechuic acid 4.61% that gets dry extract, residue protocatechuic acid content is 0.18%, extraction ratio of effective constituents is 89.64%.