CN101377456B - Magnetic conversion separating apparatus - Google Patents
Magnetic conversion separating apparatus Download PDFInfo
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- CN101377456B CN101377456B CN2007101479475A CN200710147947A CN101377456B CN 101377456 B CN101377456 B CN 101377456B CN 2007101479475 A CN2007101479475 A CN 2007101479475A CN 200710147947 A CN200710147947 A CN 200710147947A CN 101377456 B CN101377456 B CN 101377456B
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Abstract
A magnetic converting and separating device comprises a main body, at least a groove set, at least a magnetic component and at least a test tube slot. The main body comprises an upper base body and a lower base body; the upper base body and the lower base body are connected in penetration way roughly at the central parts via an articulating shaft so that the upper base body and the lower base body can rotate relative to each other taking the articulating shaft as the centre; the at least one groove set is composed of two cambered grooves with opposite curvature; the two cambered grooves are respectively arranged at the opposite faces of the upper base body and the lower base body; the magnetic component is embedded in the two cambered grooves of the groove set; the test tube slot is arranged at the outer periphery of at least one of the two base bodies of the main body; therefore, when the upper base body and the lower base body rotate relative to each other, the two base bodies can drive the magnetic component to move in the groove set so as to make the magnetic component approach or depart from the test tube slot.
Description
Technical field
The invention relates to a kind of magnetic conversion separating apparatus, refer in particular to a kind of by mechanism's rotation change magnet and sample cell relative position, micro-target substance can be separated from the potpourri of complexity with this, obtain high purity substance, the magnetic particle tripping device that carries out in order to the purifying aftertreatment.
Background technology
Magnetic separator is the separation and purification that is applied to magnetic particle, can efficient micro-target substance be separated from the potpourri of complexity, obtains the high material of purity.But in general magnetic resolution program, when isolating magnetic particle and removing the solution that remains not, must clean, dash the step of putting forward repeatedly, and this repeatedly step often need test tube taken out from separation vessel and carry out, this measure not only increases the chance that reaction solution overflows and looses and pollute mutually, often increases time consumption and inconvenience when the pipe number is many.
Present known magnetic separator structure mainly is divided into two classes, wherein a class is with bar-shaped (rod), pen type or in conjunction with the form of micro-pipette (pipette), for example U.S.'s patent of invention US6468810 " Magnetic particle transfer device and method ", US5647994 " Method andapparatus for separating magnetic particles from a solution " and US6455325 known patents such as " Liquid processing method making use of pipette device and apparatus forsame " all belongs to this class formation; It mainly is that the probe position with magnetic is invaded in the test solution of desire separation, directly draws the magnetic medium of having recognized the target biomolecule in solution; Only the shortcoming of this mode is, must put droppable protective sleeve at the magnetic position and prevent pollution between solution, and is cumbersome in the use.In addition, owing to need direct contact separation test solution, therefore there is non-narrow spectrum impurity to attach easily and influences the efficient of purifying, also destroy the target biomolecule that to collect easily.
Secondly, another kind of is to carry out purification procedures in the mode that magnetic force adds, and its advantage is to reduce the pollution problem that direct contact separation test solution is caused; U.S.'s patent of invention US5571481 " Magnetic capture rack with slidable magnetic member " for example, this case discloses a kind of magnetic devices, it is the tool that has a plural straight line array sample cell by, and one slidably reach the magnet assemblies that detaches and constitute, slide by the parallel array direction that should the plural number sample cell of this magnet assemblies of reciprocal driving, can produce or remove this magnet assemblies to being arranged at the magnetic of the test tube in this sample cell, in order to micro-target substance by separating in the invisible spectro potpourri; In view of the above as can be known, this magnetic devices must possess enough spaces that is provided with, and can hold this sample cell tool, and the magnet assemblies that should back and forth drive.
Secondly, as U.S. patent of invention US5705062 " Analytical device for separatingmagnetic microparticles from suspensions ", disclosed magnetic trace tripping device, its be with opposite polarity group of magnets ring-type array on a cup dolly, this base is provided with a circular passage, this passage is by between this opposite polarity magnet tissue, moreover, be provided with a rotating disk in this cup dolly top, the position of corresponding this group of magnets of this rotating disk is respectively equipped with the plural sample cell that can plug test tube, when driving this rotating disk rotation, can drive the test tube that is inserted in sample cell moves in this passage, and repeatedly by this opposite polarity group of magnets, with this with micro-target substance by separating in the invisible spectro potpourri; Only, this magnetic trace tripping device must drive rotating disk by the drive unit that adds, can make test tube accurately be positioned in the group of magnets, and its group of magnets has certain angle that is provided with, moreover, its base must possess enough spaces that is provided with, and can hold the passage that this group of magnets and setting allow that the test tube of rotating disk passes through.
Summary of the invention
Because the defective of known technology, the object of the present invention is to provide a kind of magnetic conversion separating apparatus, according to the demand in the magnetic separation step process, can change the intensity of magnetic at any time, do not need to take out repeatedly test tube, not only can significantly reduce expending of processing time, more can lower the chance of overflowing and loosing and polluting mutually.
For achieving the above object, magnetic conversion separating apparatus provided by the invention, it comprises:
One body, it comprises a upper pedestal and a lower base, and about center of this upper pedestal and this lower base wears with a drive-connecting shaft, and making this upper pedestal and this lower base can drive-connecting shaft be that the center rotates relatively;
At least one groups of slots, it is made of two opposite arcuate furrows of curvature, this two arcuate furrow be arranged at respectively this upper pedestal and this lower base towards face on;
At least one magnet assembly, it is embedded in two arcuate furrows of this groups of slots;
At least one test tube slot, in order to test tube to be set, this test tube slot is arranged at the outer peripheral edges of this upper pedestal or this lower base;
With this, when this upper pedestal and this lower base rotate relatively, can drive this magnet assembly and in this groups of slots, move, make this magnet assembly can near or away from this test tube slot.
Described magnetic conversion separating apparatus, wherein, two arcuate furrows of this groups of slots comprise:
Arcuate furrow on one, it is arranged at the bottom surface of this upper pedestal, and extends towards this upper pedestal outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
Arcuate furrow once, it is arranged at the end face of this lower base, and extends towards this lower base outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
When this upper pedestal and this lower base rotated relatively, it was interlaced to drive on this arcuate furrow and this arc lower groove.
Described magnetic conversion separating apparatus, wherein, arcuate furrow and this arc lower groove are to be parallel to the X-Y two dimensional surface to extend on this; Make magnet assembly have X-Y two dimension one-movement-freedom-degree.
Described magnetic conversion separating apparatus, wherein, this X-Y plane is meant surface level.
Described magnetic conversion separating apparatus, wherein, arcuate furrow and this arc lower groove are made the X-Y-Z three-dimensional extension on this; Make magnet assembly have the three-dimensional one-movement-freedom-degree of X-Y-Z.
Described magnetic conversion separating apparatus, wherein, arcuate furrow and this arc lower groove have one and present the curved surface of downtrending towards the body outer rim by drive-connecting shaft on this.
Described magnetic conversion separating apparatus, wherein, arcuate furrow and this arc lower groove have one and present the curved surface of ascendant trend towards the body outer rim by drive-connecting shaft on this.
Described magnetic conversion separating apparatus, wherein, this upper pedestal and this lower base are all in the form of annular discs, and this drive-connecting shaft is arranged in the center of this upper pedestal and this lower base.
Described magnetic conversion separating apparatus, wherein:
The center of this upper pedestal is provided with a circular hole that axially connects;
This drive-connecting shaft is arranged at this lower base center and extends axially certain-length, and this drive-connecting shaft is arranged in the circular hole at this upper pedestal center, makes this lower base and this upper pedestal constitute the relation of pivot joint.
Described magnetic conversion separating apparatus, wherein, the circular hole top at this upper pedestal center is provided with a bearing, and this bearing hinge joint is in this drive-connecting shaft top.
Described magnetic conversion separating apparatus, wherein, this test tube slot is one to run through set this pedestal top and the manhole of bottom, this manhole axially and the axially parallel of this drive-connecting shaft.
Described magnetic conversion separating apparatus, wherein, this manhole radially connects the outer peripheral edges of this set pedestal, make these pedestal outer peripheral edges constitute a saturating dead slot, between these saturating dead slot both sides and this pedestal, respectively be provided with at least one intermediate plate, in order to providing this saturating dead slot to have elasticity folding ability, but and this test tube of clamping.
Described magnetic conversion separating apparatus, wherein, the lateral wall of this body is provided with the protruding list structure of plural number, in order to provide the user to grasp or to have certain friction force when rotating this body.
Described magnetic conversion separating apparatus, wherein, the bottom of this body is provided with slipmat, has certain friction force in order to the interplanar that this body and its setting are provided.
Described magnetic conversion separating apparatus, wherein, this magnet assembly can be magnet, electromagnet one of them or its combination.
In sum, magnetic conversion separating apparatus provided by the present invention, by relatively turnable two pedestals, and the groups of slots that two opposite arcuate furrows of curvature constitute designs, not only can so that test tube away from the magneticaction scope of magnet, reach easy magnetic shield effect, more help the microminiaturization of single unit system; The present invention is according to the demand in the magnetic separation step process, can change the intensity of magnetic at any time, do not need to take out repeatedly test tube and can carry out the step of cleaning in the magnetic resolution program, not only can significantly reduce expending of processing time, more can lower the chance of overflowing and loosing and polluting mutually; Simultaneously, its rotating process is reversible, can give magneticaction again with demand, carries out the removal that object dashes the back magnetic particle of carrying (elute).
Description of drawings
Fig. 1 is the decomposition texture stereographic map of the embodiment of the invention.
Fig. 2 is the unitized construction stereographic map of the embodiment of the invention.
Fig. 3 is the vertical view of the unitized construction of the embodiment of the invention.
Fig. 4 to Fig. 6 is a start process synoptic diagram of the present invention.
Fig. 7 is the axial section structural representation of another embodiment of the present invention.
Main mark explanation in the accompanying drawing:
10,100-body
11,110-upper pedestal
The 111-circular hole
The 112-bearing
The 113-rivet
114-projection list structure
12,120-lower base
121,1210-drive-connecting shaft
The 122-slipmat
The 20-groups of slots
21, the last arcuate furrow of 210-
22,220-arc lower groove
30,300-magnet assembly
The 40-test tube slot
The saturating dead slot of 41-
The 42-intermediate plate
The 50-test tube
The 51-magnetic particle
52-solution
Embodiment
Magnetic conversion separating apparatus provided by the invention, it comprises:
One body, it comprises a upper pedestal and a lower base, and about center of this upper pedestal and this lower base is to wear with a drive-connecting shaft, and making this upper pedestal and this lower base can drive-connecting shaft be that the center rotates relatively;
At least one groups of slots, it is made of two opposite arcuate furrows of curvature, this two arcuate furrow be arranged at respectively this upper pedestal and lower base towards face on;
At least one magnet assembly, it is embedded in two arcuate furrows of this groups of slots;
At least one test tube slot, in order to test tube to be set, this test tube slot is arranged at the outer peripheral edges of a pedestal wherein;
With this, when this upper pedestal and this lower base rotate relatively, can drive this magnet assembly and in this groups of slots, move, make this magnet assembly can near or away from this test tube slot.
Wherein two arcuate furrows of this groups of slots comprise:
Arcuate furrow on one, it is arranged at the bottom surface of this upper pedestal, and extends towards this upper pedestal outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
Arcuate furrow once, it is arranged at the end face of this lower base, and extends towards this lower base outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
When this upper pedestal and lower base rotated relatively, it was interlaced to drive on this arcuate furrow and this arc lower groove.
Wherein should go up arcuate furrow and this arc lower groove is to be parallel to the X-Y two dimensional surface to extend; Make magnet assembly have X-Y two dimension one-movement-freedom-degree.
Wherein this X-Y plane is meant surface level.
Wherein should go up arcuate furrow and this arc lower groove is to make the X-Y-Z three-dimensional extension; Make magnet assembly have the three-dimensional one-movement-freedom-degree of X-Y-Z.
Wherein should go up arcuate furrow and this arc lower groove has one and presents the curved surface of downtrending towards the body outer rim by drive-connecting shaft.
Wherein should go up arcuate furrow and this arc lower groove has one and presents the curved surface of ascendant trend towards the body outer rim by drive-connecting shaft.
Wherein this upper pedestal and this lower base are all in the form of annular discs, and this drive-connecting shaft is arranged in the center of this upper pedestal and lower base.
Wherein:
The center of this upper pedestal is provided with a circular hole that axially connects;
This drive-connecting shaft is arranged at this lower base center and extends axially certain-length, and this drive-connecting shaft is arranged in the circular hole at this upper pedestal center, makes this lower base and this upper pedestal constitute the relation of pivot joint.
Wherein the circular hole top at this upper pedestal center is provided with a bearing, and this bearing hinge joint is in this drive-connecting shaft top.
Wherein this test tube slot is one to run through the top of set pedestal and the manhole of bottom, this manhole axially and the axially parallel of this drive-connecting shaft.
Wherein this manhole is the outer peripheral edges that radially connect set pedestal, make these pedestal outer peripheral edges constitute a saturating dead slot, between these saturating dead slot both sides and this pedestal, respectively be provided with at least one intermediate plate, have elasticity folding ability in order to this saturating dead slot to be provided, but and holding test tubes.
Wherein the lateral wall of this body is provided with the protruding list structure of plural number, in order to provide the user to grasp or to have certain friction force when rotating this body.
Wherein the bottom of this body is provided with slipmat, has certain friction force in order to the interplanar that this body and its setting are provided.
Wherein this magnet assembly can be magnet, electromagnet one of them or its combination.
Further understand and approval for having structure purpose of the present invention and effect, conjunction with figs. describe in detail as after.
Describe the present invention for reaching employed technological means of purpose and effect hereinafter with reference to accompanying drawing, and the cited embodiment of the following drawings only is an aid illustration, but technological means of the present invention is not limited to cited accompanying drawing.
See also Fig. 1 to shown in Figure 3, magnetic conversion separating apparatus provided by the invention, it comprises the groups of slots 20 of a body 10, plural number, the magnet assembly 30 (magnet assembly only is shown among the figure) of plural number and the test tube slot 40 of plural number.
This body 10 comprises a upper pedestal 11 and a lower base 12, this upper pedestal 11 is all in the form of annular discs with this lower base 12, be provided with a circular hole 111 that axially connects in the center of this upper pedestal 11, extend axially certain-length in these lower base 12 centers and be provided with a drive-connecting shaft 121, this drive-connecting shaft 121 is arranged in the circular hole 111 at these upper pedestal 11 centers, circular hole 111 tops in these upper pedestal 11 centers are provided with a bearing 112, be connected in this drive-connecting shaft 121 tops after being arranged in this bearing 112 by a rivet 113, so, can make this upper pedestal 11 and this lower base 12 constitute the relation of pivot joint, this upper pedestal 11 and this lower base 12 can this drive-connecting shaft 121 be rotated for the center relatively.
This groups of slots 20 be by arcuate furrow 21 on, once arcuate furrow 22 is constituted, and is provided with six groups of groups of slots 20 in present embodiment; Should go up arcuate furrow 21 and arc lower groove 22 be arranged at this upper pedestal 11 and lower base 12 towards face on, as shown in Figure 1, should go up the bottom surface that arcuate furrow 21 is arranged at this upper pedestal 11, and extend towards these upper pedestal 11 outer peripheral edges arcs by this drive-connecting shaft 121 is radially centrifugal; This arc lower groove 22 is arranged at the end face of this lower base 12, and extends towards these lower base 12 outer peripheral edges arcs by this drive-connecting shaft 121 is radially centrifugal; It must be emphasized that curvature of arcuate furrow 21 and arc lower groove 22 is opposite on this.
Be provided with magnet assembly 30 between this upper pedestal 11 and this lower base 12, this magnet assembly 30 is one to present columned permanent magnet, and its two ends are arranged in respectively in the corresponding up and down last arcuate furrow 21 and arc lower groove 22; Mandatory declaration be, the quantity of this magnet assembly 30 shows six groups of groups of slots 20 corresponding to the quantity that is provided with of this groups of slots 20 with accompanying drawing, six magnet assemblies 30 of should arranging in pairs or groups, among the figure only representativeness illustrate one; In addition, this magnet assembly 30 also can adopt electromagnet etc. other has the assembly of magnetic.
Secondly, this test tube slot 40 is arranged at the outer peripheral edges of this upper pedestal 11, the axially parallel of axial and this drive-connecting shaft 121 of this test tube slot 40; Similarly, the quantity of this test tube slot 40 is corresponding to the quantity that is provided with of this groups of slots 20, to show six groups of groups of slots 20, six test tube slot 40 of should arranging in pairs or groups in scheming; This test tube slot 40 is one to run through the manhole of the top and the bottom of this upper pedestal 11, and this manhole radially connects the outer peripheral edges of this upper pedestal 11, make these upper pedestal 11 outer peripheral edges constitute a saturating dead slot 41, between these saturating dead slot 41 both sides and this upper pedestal 11, respectively be provided with at least one intermediate plate 42, can provide this saturating dead slot 41 to have elasticity folding ability by this intermediate plate 42, but and holding test tubes 50 (being shown in Fig. 2).
Moreover, be provided with the protruding list structure 114 of plural number in the lateral wall of this upper pedestal 11, in order to provide the user to grasp this body 10 or to have certain friction force when rotating this upper pedestal 11; And, be provided with slipmat 122 in the bottom of this lower base 12, in order to being provided, this body 10 and the interplanar of its setting have certain friction force.
Seeing also Fig. 4 to Fig. 6, is example with one group of groups of slots 20, magnet assembly 30 and test tube 50, and start process of the present invention is described; Shown in 4 four, this magnet assembly 30 is positioned at the last arcuate furrow 21 of groups of slots 20, the outboard end of arc lower groove 22, and at this moment, this magnet assembly 30 can produce magnetic force to the potpourri in this test tube 50 near this test tube 50; See also shown in Figure 5, when being rotated counterclockwise this upper pedestal 11 (also can oppositely rotate this lower base 12 simultaneously), in the process that arcuate furrow 21, arc lower groove 22 interlock on this, can drive this magnet assembly 30 is moved by the medial extremity of outboard end arcuate furrow 21, arc lower groove 22 on this of arcuate furrow on this 21, arc lower groove 22, simultaneously, this test tube 50 also rotates synchronously along with the rotation of this upper pedestal 11; See also shown in Figure 6, when continuing to be rotated counterclockwise this upper pedestal 11, make this magnet assembly 30 march to the medial extremity of arcuate furrow 21 on this, arc lower groove 22, at this moment, this magnet assembly 30 is eliminated the magnetic force that potpourri produced in this test tube 50 fully away from this test tube 50; If oppositely be operated to Fig. 4, then can drive this magnet assembly 30 once again near this test tube 50 by Fig. 6.
With regard to the foregoing description, see also Fig. 1 and shown in Figure 3, should go up arcuate furrow 21 is to be parallel to X-Y two dimensional surface (that is surface level) to extend with this arc lower groove 22, and in the extension process, should go up arcuate furrow 21 and all keep certain depth with this arc lower groove 22, make this magnet assembly 30 have X-Y two dimension one-movement-freedom-degree, that is the mobile route of this magnet assembly 30 does not have height change.
Except that the foregoing description, see also another embodiment of the present invention shown in Figure 7, Fig. 7 embodiment shows a body 100, this body 100 comprises a upper pedestal 110 and a lower base 120, this upper pedestal 110 and lower base 120 are articulated mutually by drive-connecting shaft 1210, bearing 112 and rivet 113, and this upper pedestal 110 and this lower base 120 can this drive-connecting shaft 1210 be rotated for the center relatively; Be provided with arcuate furrow 210 in the bottom surface of this upper pedestal 110, end face in this lower base 120 is provided with arc lower groove 220, should go up arcuate furrow 210 and arc lower groove 220 in the extension state of X-Y plane, identical with upward arcuate furrow 21 and arc lower groove 22 embodiment illustrated in fig. 3, do not repeat them here, and the characteristics of Fig. 7 embodiment are, should go up arcuate furrow 210 and arc lower groove 220 has one and presents the curved surface of downtrending towards body 100 outer rims by drive-connecting shaft 1210, that is the degree of depth that should go up arcuate furrow 210 and arc lower groove 220 has Z axle height fall, in other words, arcuate furrow 210 is to make the X-Y-Z three-dimensional extension with this arc lower groove 220 on this.
When this upper pedestal 110 and the 120 relative rotations of this lower base, can drive magnet assembly 300 and have the three-dimensional one-movement-freedom-degree of X-Y-Z, as shown in Figure 7, when this magnet assembly 300 is driven near test tube 50, magnetic particle 51 in the test tube 50 can be attracted to a side of test tube 50, at this moment, can extract solution 52 in the test tube 50; And when this upper pedestal 110 of reverse drive and the 120 relative rotations of this lower base, rise to arcuate furrow 210 and arc lower groove 220 on this summit and away from this test tube 50, drive this magnet assembly 300 so repeatedly and do that X-Y-Z is three-dimensional to be moved, can make this magnet assembly 300 near or away from this test tube 50, the cleaning step in the repeated rows magnetic resolution program.
Decide on actual state, should go up the curved surface that arcuate furrow 210 and arc lower groove 220 can be set to be presented towards body 100 outer rims by drive-connecting shaft 1210 ascendant trend, that is, this magnet assembly 300 is to be climbed behind the certain altitude near this test tube 50 by this drive-connecting shaft 1210, its start principle does not repeat them here with embodiment illustrated in fig. 7 identical; In addition, the magnetic power of also visual this magnet assembly 300 of the size of this magnet assembly 300, and the physical size of this body 100 and setting, and unrestricted.
What must emphasize in addition is, Fig. 1 or embodiment illustrated in fig. 7 no matter, this presents discoid upper pedestal 11,110 and lower base 12,120, all be as explanation embodiment of the present invention, in addition, such as can be according to drive-connecting shaft any two pedestals of moulding in relative rotation, no matter square, polygon or random geometric modeling, as long as have the arcuate furrow design in its opposite face, can drive magnet assembly and move, so the shape of pedestal do not influence the usefulness that the present invention can reach.
The above only is embodiments of the invention, when can not with the scope implemented of qualification the present invention.Promptly the equalization of doing according to claim of the present invention generally changes and modifies, and all should still belong in the scope that the claim of the present patent application contains.
Claims (15)
1. magnetic conversion separating apparatus, it comprises:
One body, it comprises a upper pedestal and a lower base, and about center of this upper pedestal and this lower base wears with a drive-connecting shaft, and making this upper pedestal and this lower base can drive-connecting shaft be that the center rotates relatively;
At least one groups of slots, it is made of curvature opposite last arcuate furrow and arc lower groove, this two arcuate furrow be arranged at respectively this upper pedestal and this lower base towards face on;
At least one magnet assembly, its two ends are arranged in respectively in the corresponding up and down last arcuate furrow and arc lower groove, and the quantity of this magnet assembly is corresponding and the quantity of this groups of slots;
At least one test tube slot, in order to test tube to be set, this test tube slot is arranged at the outer peripheral edges of this upper pedestal or this lower base;
With this, when this upper pedestal and this lower base rotate relatively, drive this magnet assembly and in this groups of slots, move, make this magnet assembly can near or away from this test tube slot.
2. magnetic conversion separating apparatus as claimed in claim 1, wherein, two arcuate furrows of this groups of slots comprise:
Arcuate furrow on one, it is arranged at the bottom surface of this upper pedestal, and extends towards this upper pedestal outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
Arcuate furrow once, it is arranged at the end face of this lower base, and extends towards this lower base outer peripheral edges arc by this drive-connecting shaft is radially centrifugal;
When this upper pedestal and this lower base rotate relatively, drive should go up arcuate furrow and this arc lower groove interlaced.
3. magnetic conversion separating apparatus as claimed in claim 2, wherein, arcuate furrow and this arc lower groove are to be parallel to the X-Y two dimensional surface to extend on this; Make magnet assembly have X-Y two dimension one-movement-freedom-degree.
4. magnetic conversion separating apparatus as claimed in claim 3, wherein, this X-Y plane is meant surface level.
5. magnetic conversion separating apparatus as claimed in claim 2, wherein, arcuate furrow and this arc lower groove are made the X-Y-Z three-dimensional extension on this; Make magnet assembly have the three-dimensional one-movement-freedom-degree of X-Y-Z.
6. magnetic conversion separating apparatus as claimed in claim 5, wherein, arcuate furrow and this arc lower groove have one and present the curved surface of downtrending towards the body outer rim by drive-connecting shaft on this.
7. magnetic conversion separating apparatus as claimed in claim 5, wherein, arcuate furrow and this arc lower groove have one and present the curved surface of ascendant trend towards the body outer rim by drive-connecting shaft on this.
8. magnetic conversion separating apparatus as claimed in claim 1, wherein, this upper pedestal and this lower base are all in the form of annular discs, and this drive-connecting shaft is arranged in the center of this upper pedestal and this lower base.
9. magnetic conversion separating apparatus as claimed in claim 8, wherein:
The center of this upper pedestal is provided with a circular hole that axially connects;
This drive-connecting shaft is arranged at this lower base center and extends axially certain-length, and this drive-connecting shaft is arranged in the circular hole at this upper pedestal center, makes this lower base and this upper pedestal constitute the relation of pivot joint.
10. magnetic conversion separating apparatus as claimed in claim 9, wherein, the circular hole top at this upper pedestal center is provided with a bearing, and this bearing hinge joint is in this drive-connecting shaft top.
11. magnetic conversion separating apparatus as claimed in claim 1, wherein, this test tube slot is one to run through set this pedestal top and the manhole of bottom, this manhole axially and the axially parallel of this drive-connecting shaft.
12. magnetic conversion separating apparatus as claimed in claim 11, wherein, this manhole is the outer peripheral edges at this set pedestal of the axial perforation that is parallel to this drive-connecting shaft, make these pedestal outer peripheral edges constitute a saturating dead slot, between these saturating dead slot both sides and this pedestal, respectively be provided with at least one intermediate plate, in order to providing this saturating dead slot to have elasticity folding ability, but and this test tube of clamping.
13. magnetic conversion separating apparatus as claimed in claim 1, wherein, the lateral wall of this body is provided with the protruding list structure of plural number.
14. magnetic conversion separating apparatus as claimed in claim 1, wherein, the bottom of this body is provided with slipmat.
15. magnetic conversion separating apparatus as claimed in claim 1, wherein, this magnet assembly is one of them or its combination of magnet, electromagnet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101479475A CN101377456B (en) | 2007-08-27 | 2007-08-27 | Magnetic conversion separating apparatus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101479475A CN101377456B (en) | 2007-08-27 | 2007-08-27 | Magnetic conversion separating apparatus |
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| CN101377456A CN101377456A (en) | 2009-03-04 |
| CN101377456B true CN101377456B (en) | 2010-12-08 |
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| CN2007101479475A Expired - Fee Related CN101377456B (en) | 2007-08-27 | 2007-08-27 | Magnetic conversion separating apparatus |
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| CN105728189B (en) * | 2016-04-25 | 2018-01-23 | 中国石油化工股份有限公司 | Supervising device with magnetic fixture and using the fixture |
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| US5647994A (en) * | 1993-06-21 | 1997-07-15 | Labsystems Oy | Method and apparatus for separating magnetic particles from a solution |
| US5705062A (en) * | 1993-09-17 | 1998-01-06 | Hoffmann-La Roche Inc. | Analytical device for separating magnetic microparticles from suspensions |
| US5571481A (en) * | 1995-02-17 | 1996-11-05 | Vicam, L.P. | Magnetic capture rack with slidable magnetic member |
| US6455325B1 (en) * | 1995-03-20 | 2002-09-24 | Precision System Science Co., Ltd. | Liquid processing method making use of pipette device and apparatus for same |
| US6468810B1 (en) * | 1998-02-23 | 2002-10-22 | Bio-Nobile Oy | Magnetic particle transfer device and method |
| CN101019026A (en) * | 2004-08-23 | 2007-08-15 | 基斯特-欧洲研究协会 | Microfluid system for the isolation of biological particles using immunomagnectic separation |
| CN1950153A (en) * | 2005-04-28 | 2007-04-18 | 株式会社日立制作所 | Magnetic separation cleaning apparatus and magnetic separation cleaning method |
| CN2925616Y (en) * | 2006-07-20 | 2007-07-25 | 上海奥润微纳新材料科技有限公司 | Universal magnetic separating stand |
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| CN101377456A (en) | 2009-03-04 |
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