CN101366726A - Medicament composition for treating skin diseases - Google Patents
Medicament composition for treating skin diseases Download PDFInfo
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- CN101366726A CN101366726A CNA2008101393892A CN200810139389A CN101366726A CN 101366726 A CN101366726 A CN 101366726A CN A2008101393892 A CNA2008101393892 A CN A2008101393892A CN 200810139389 A CN200810139389 A CN 200810139389A CN 101366726 A CN101366726 A CN 101366726A
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Abstract
The invention relates to a medical composition for treating skin diseases, which belongs to the pharmacy technical field. The medical composition for treating the skin disease is made of the following raw materials: 10 to 35 grams of benzoic acid, 20 to 30 grams of salicylic acid, 20 to 30 grams of camphor, 30 milliliters of glycerol, 1.5 grams of iodine plates and 10 grams of borneol. The medical composition is used for treating the skin diseases such as beriberi and so on, has the advantages of quickness in relieving itching, obvious effect, good treatment effect, high cure rate and difficulty in recrudescence, is one of the ideal externally applied agents at present, and has wide practicality.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of pharmaceutical composition that is used for the treatment of dermatosis.Pharmaceutical composition indication of the present invention is: dermatosis such as vitamin B1 deficiency, tinea unguium, tinea cruris, tinea capitis.
Background technology
Vitamin B1 deficiency is fragrant lane foot, tinea pedis etc. again.It is a kind of common clinical, is again frequently-occurring disease, also is the repeated relapsing dermatosis.Good sending out between the toe bifurcation.Symptom is local pruritus, the vesicle of having peeled, and scratches the back and festers evening, and severe patient easily causes infection, locally occurs redly, swollen, hot, bitterly, and whole body generates heat, dysfunction, shape sound people's working healthily and life.Once ill outbreak repeatedly is difficult throughout the year.
The beriberic medicament categories of treatment is a lot of at present, and unguentum, water preparation and Chinese medicine bubble method are arranged, and just all can not reach ideal healing purpose.Alleviate or the effect of respite symptom though can only play, also be difficult to reach the purpose of healing with the medicine-feeding clinical application for many years.
Notification number is that the Chinese patent of CN100356910C discloses a kind of pharmaceutical composition for the treatment of beriberi.Mainly solved the problem that existing beriberi can not be effected a radical cure, be shown effect repeatedly.It is characterized in that: make by weight: 2～10 parts of Camphoras, 10～30 parts in sulfur, 1～10 part of Calomelas, 0.1～0.2 part of meticorten sheet, 1～5 part of salicylic acid, 1～10 part of Borneolum Syntheticum, 50～100 parts in vaseline by following raw materials according.This pharmaceutical composition has short treating period, instant effect, characteristics that cure rate is high to vitamin B1 deficiency.Its weak point is careful this composition of using of vitamin B1 deficiency that has meticorten, Mycophyta to cause in the compositions.
Summary of the invention
The invention provides a kind of pharmaceutical composition for the treatment of dermatosis, be used for dermatosis such as vitamin B1 deficiency, have antipruritic soon, effect is obvious, good effect, and the cure rate height is difficult for advantages such as recurrence.Be one of comparatively ideal external used medicine at present, have practicality widely.
The following technical scheme of the concrete employing of the present invention:
The beriberic pharmaceutical composition of a kind of treatment is characterized in that, is made by following raw material: benzoic acid 10-35 gram, salicylic acid 20-30 gram, Camphora 20-30 gram, 30 milliliters of glycerol, iodine tablet 1.5 grams, Borneolum Syntheticum 10 grams.
Adopt preparation of pharmaceutical compositions solution of the present invention, comprise the steps: just benzoic acid 10-35 gram, salicylic acid 20-30 gram, Camphora 20-30 gram, 30 milliliters of glycerol, iodine tablet 1.5 grams, be dissolved in 500～1000 milliliter of 75 degree ethanol after Borneolum Syntheticum 10 grams mix, make described solution.
The indication of pharmaceutical composition of the present invention is: dermatosis such as vitamin B1 deficiency, tinea unguium, tinea cruris, tinea capitis.
Using method: external preparation for skin is coated with or is sprayed on the affected part, 1-2 time on the one.When being used for head, should adopt the ethanol dissolved dilution of upper limit amount.
Untoward reaction:, have of short duration after the medication or one cross the property burn feeling to the skin of scratching.
Taboo: 1: this drug allergy person is forbidden.
2: forbid oral.
3: child and infant forbidding.
Points for attention: 1, this product can not be used for eye, mouthful delicate position.
2. ulcer, the infected's skin should temporarily be stopped using.
The pharmacological action of medicine of the present invention: benzoic acid, salicylic acid, Camphora; stronger fungicidal action is arranged; iodine tablet, Borneolum Syntheticum, 75 degree ethanol play sterilization, sterilization, antipruritic to skin; mix to use and can effectively kill fungus, dissolving cutin, antipruritic rapidly, glycerol plays lubricated skin, prevents to chap, protect skin, alleviates the stimulation of medicine to epidermis.
Anemia of pregnant woman and women breast-feeding their children Ying Shenyong.
Effect duration: 3 years.
Compare with the prior art other drug, the solution clinical practice that the present invention makes is not only antipruritic fast, and effect is obvious, good effect, and the cure rate height, difficult recurrence is one of comparatively ideal external used medicine at present, has practicality widely.
Below further set forth beneficial effect of the present invention by clinical observation on the therapeutic effect, concrete case.The commodity of the present invention when clinical trial are called " the bifurcation bifurcation is clean ".
One, clinical observation on the therapeutic effect test (is example to be used for the treatment of vitamin B1 deficiency)
1. clinical data
Year accept 682 routine patients altogether for medical treatment from nineteen ninety-2008.Once repeatedly adopting Drug therapys such as unguentum, bubble lotion, tinea liquid not heal repeatedly, adopted the solution of pharmaceutical composition of the present invention voluntarily---the bifurcation bifurcation is treated only.Cure 452 routine male patients, 230 routine women patients, 16-78 years old ages, 38 years old mean age.Biped toe 380 examples wherein, monopodia toe 302 examples, medical history is the longest 25 years, and is the shortest 2 months.
2. treat and method
It is clean with the eliminating cold for resuscitation washing to suffer from foot earlier, is stained with the clean liquid medicine of bifurcation bifurcation with cotton rod after drying and evenly embrocates the affected part airing.One day 1-2 times, 7 days is a course of treatment, and general continuous use can be healed 1-2 courses of treatment.
3. judgement standard
Position skin plays red blood blister between foot limit, toes, toe, pruritus, blister, festers, flow and glue water, desquamation, chap.The microscopy fungus is all positive, is diagnosed as vitamin B1 deficiency.
4. criterion of therapeutical effect
Cure: symptom and sign disappear, microscopy fungus feminine gender.
Take a turn for the better: symptom and sign are clearly better, and the microscopy fungus is positive.
Invalid: the symptom and sign no change.
5. therapeutic outcome:
682 routine patients cure 670 examples, account for 98%.Dodge the microscopy fungus on every Mondays, continuous 2 weeks are negative.9 examples that take a turn for the better account for 1.3%, continuous 2 microscopy positives.Invalid 2 examples account for 0.4%, the microscopy positive.2 examples are because of 5 days stopped treatments of medication again.
Illustrate: use reliable, the difficult recurrence of the clean beriberi medicine liquid treatment of self-control bifurcation bifurcation vitamin B1 deficiency curative effect.Can be used as the effective ways of treatment vitamin B1 deficiency, tinea pedis, be worthy of popularization.
Two, medical record for example
Case 1
King XX, the man, 45 years old this year, the millworker, self-induction bilateral foot bifurcation is itched before 10 years, and is rubescent, played several small red dots, scratches the sticking water of the rotten to the corn stream in back, and several years fails to cure repeatedly.The beriberi recurrence is itched unbearably during first visit, and all day, hands was not from foot.Flea grabs unfortunate infection, and local rubescent, foot begins swelling, and it is many that the whole body hyperpyrexia reaches 39 degree, can not go to work in more than 10 day with descending.Adopt the solution of pharmaceutical composition of the present invention to smear, every day 1-2 times, fully recover after using two weeks continuously.Observe and do not have recurrence in 3 years.
Case 2
Lee XX, in 59 years old this year, the cadre suffers from vitamin B1 deficiency accidentally when joining the army in army, and in several years whens treatment, heavily never healed when light entirely.Afterwards toenail also slowly distortion thicken, Army Hospital checks that be diagnosed as vitamin B1 deficiency companion tinea unguium is fungal infection, in the past few years also adopts multiple Drug therapy can not heal entirely all the time in the place.Adopt the solution of pharmaceutical composition of the present invention to smear, every day 1-2 times, use recovery from illness after month continuously.Observe and do not have recurrence in 2 years.
Case 3
Liu XX, the man, 68 years old now, move back the body worker, suffered from vitamin B1 deficiency more than 20 year.20 ground uprooting weed down several years ago, the foot bifurcation has begun little red pimple, very itches, and once takes a turn for the better with other multiple Drug therapys, and annual certain sky begins recurrence, increases the weight of year by year.Begin to have only that the foot bifurcation is itched, got blister, rotten to the corn, the sticking water of stream, afterwards around the foot limit also desquamation chap.Whenever being on tenterhooks of itching in evening, influence work and life, treatment was not all the year round healed entirely, the time weight when light.Adopt the solution of pharmaceutical composition of the present invention to smear, use recovery from illness after 10 days continuously every day 1-2 times, observe and do not have recurrence in 3 years.
The specific embodiment
Embodiment 1-3: composition of raw materials
| Benzoic acid | Salicylic acid | Camphora | Glycerol | Iodine tablet | Borneolum Syntheticum | |
| Embodiment 1 | 25 | 25 | 20 | 30ml | 1.5g | 10g |
| Embodiment 2 | 10 | 20 | 25 | 30ml | 1.5g | 10g |
| Embodiment 3 | 35 | 30 | 30 | 30ml | 1.5g | 10g |
Embodiment 4: make spray
The raw material of any prescription among the embodiment 1-3 is dissolved in the 1000ml75 degree ethanol, and dissolving makes spray.
Embodiment 5: liniment
The raw material of any prescription among the embodiment 1-3 is dissolved in the 500ml75 degree ethanol, and dissolving makes liniment.
Claims (2)
1. a pharmaceutical composition for the treatment of dermatosis is characterized in that, is made by following raw material: benzoic acid 10-35 gram, salicylic acid 20-30 gram, Camphora 20-30 gram, 30 milliliters of glycerol, iodine tablet 1.5 grams, Borneolum Syntheticum 10 grams.
2. the pharmaceutical composition of treatment dermatosis according to claim 1, it is characterized in that, adopt the preparation of pharmaceutical compositions solution of claim 1, comprise the steps: gram, salicylic acid 20-30 gram, Camphora 20-30 gram with benzoic acid 10-35,30 milliliters of glycerol, iodine tablet 1.5 grams are dissolved in 500～1000 milliliter of 75 degree ethanol after Borneolum Syntheticum 10 grams mix, and make described solution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101393892A CN101366726A (en) | 2008-09-05 | 2008-09-05 | Medicament composition for treating skin diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101393892A CN101366726A (en) | 2008-09-05 | 2008-09-05 | Medicament composition for treating skin diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101366726A true CN101366726A (en) | 2009-02-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101393892A Pending CN101366726A (en) | 2008-09-05 | 2008-09-05 | Medicament composition for treating skin diseases |
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| CN (1) | CN101366726A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320519A (en) * | 2017-08-29 | 2017-11-07 | 王红芝 | One kind treats dermopathic ointment |
| CN109224033A (en) * | 2018-10-23 | 2019-01-18 | 陈晋广 | It is a kind of to treat dermopathic ointment and preparation method thereof |
| CN113797223A (en) * | 2020-06-17 | 2021-12-17 | 徐旺 | Ointment for treating beriberi |
| CN113876802A (en) * | 2020-07-02 | 2022-01-04 | 宋芳芳 | Beriberi antibacterial liquid |
-
2008
- 2008-09-05 CN CNA2008101393892A patent/CN101366726A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320519A (en) * | 2017-08-29 | 2017-11-07 | 王红芝 | One kind treats dermopathic ointment |
| CN109224033A (en) * | 2018-10-23 | 2019-01-18 | 陈晋广 | It is a kind of to treat dermopathic ointment and preparation method thereof |
| CN113797223A (en) * | 2020-06-17 | 2021-12-17 | 徐旺 | Ointment for treating beriberi |
| CN113876802A (en) * | 2020-07-02 | 2022-01-04 | 宋芳芳 | Beriberi antibacterial liquid |
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Open date: 20090218 |