CN101352258A - Ligusticum sinense extract liquid and use thereof in tobacco - Google Patents
Ligusticum sinense extract liquid and use thereof in tobacco Download PDFInfo
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- CN101352258A CN101352258A CNA2008101412817A CN200810141281A CN101352258A CN 101352258 A CN101352258 A CN 101352258A CN A2008101412817 A CNA2008101412817 A CN A2008101412817A CN 200810141281 A CN200810141281 A CN 200810141281A CN 101352258 A CN101352258 A CN 101352258A
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- ligusticum
- extract liquid
- ligusticum sinense
- extract
- tobacco
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Abstract
The invention belongs to the field of natural plant extracts and application thereof, which particularly relates to ligusticum extracting solution and the application to cigarettes. The extracting solution is obtained by the following steps: ligusticum without impurities is dried, crushed, and then is extracted by water or ethanol or a mixture of the water and the ethanol for 5min-10h, and then is purified to obtain the ligusticum extracting solution. In the ligusticum extracting solution of the invention, the components of the ligusticum with drug effects are fully kept and extracted. The method is simple and targeted; by adding the ligusticum extracting solution to the cigarettes, the harmful ingredients in cigarette smoke are reduced without changing the existing processing technology and function of the cigarettes, the smoking safety and comfort are improved, the functional ingredients beneficial to human body are increased, a Chinese cigarette with a certain characteristics is formed, which is significant to form the core technology of Chinese cigarette technologies, and causes the cigarettes to be readily accepted by consumers, therefore, the ligusticum extracting solution has relatively great market potential.
Description
(1) technical field
The invention belongs to extracted form natural plant and application, particularly ligusticum sinense extract liquid and the application in tobacco thereof.
(2) background technology
China is the plant resources more rich country that compares in the world, floristics is above 30,000 kinds, quantity accounts for the third place in the world, wherein about 10,000 kinds can be used for medicine, and Chinese traditional traditional Chinese medicine is the quintessence of Chinese culture of China, has the long history in thousands of years, the cultural connotation inside information is deep, wherein some plant has concurrently medicinal and edible function, is used widely in different field for a long time, and has affluent resources.
Jehol Ligusticum Rhizome is a samphire, is Chinese herbal medicine commonly used.Medicinal Jehol Ligusticum Rhizome mainly contains Umbelliferae Ligusticum plant Jehol Ligusticum Rhizome (Ligusticum sinense Oliv.), 3 kinds of Ligusticum jeholense (Ligusticum jeholense NakaietKitag) and rhizome of chuanxiong platymiscium Xinjiang, Umbelliferae mountain Jehol Ligusticum Rhizomes (Coniselium vaginatum Thell).The Chinese medicine Jehol Ligusticum Rhizome has the effect of cold, the dehumidifying of dispeling the wind, loose, pain relieving, cures mainly anemofrigid cold, top of the head pain, rheumatism podomere numbness pain etc.Pharmacological research show Jehol Ligusticum Rhizome have anti-inflammatory, desinsection, antibacterial, suppress functions such as smooth muscle effect, hemangiectasis, hypotensive, transaminase lowering activity.Domestic relevant research mainly is at aspects such as chemical composition separation, structure evaluation, pharmacological effects.
Smoking is one of common problem of very paying close attention in world today's scope with health.How endanger and ensure and promote publilc health to become noticeable important topic by reducing tobacco.The characteristic of outstanding Chinese style cigarette reduces the harmful components in the cigarette smoke, improves smoking property of cigarette process safe and comfortableness, increases the functional components to the human body beneficial, is the inexorable trend of present tobacco industry development.
(3) summary of the invention
The object of the present invention is to provide a kind of ligusticum sinense extract liquid and be applied to the tobacco field,, improve smoking property of cigarette process safe and comfortableness, increase functional components the human body beneficial to reduce the harmful components in the cigarette smoke; Give prominence to the fragrance characteristic of Chinese style cigarette simultaneously.
The technical solution used in the present invention is as follows:
A kind of ligusticum sinense extract liquid, described extract makes by laxative remedy: will carry out drying, pulverizing through the Jehol Ligusticum Rhizome of removal of impurities, water or ethanol or both mixtures extract then, extract 5min-10h, promptly get described ligusticum sinense extract liquid after the purification.
Can adopt following manner during extraction:
Adopt the heating reflux type to carry out, heating-up temperature is 50-105 ℃, and extraction time is 0.5-10 hour, and this method recovery rate is 6-10%.。
The employing ultrasonic wave extracts, and ultrasonic frequency is 28-100KHz, and the time is 10min-6h.Adopt ultrasonic extracting mode, be to utilize cavitation effect of ultrasonic waves, quicken the effective ingredients in plant stripping, in addition the ultrasonic wave second order effect, as: mechanical shock emulsification, spread, smash, chemical effect etc., also can quicken to extract the diffusion, release of composition and fully mix with solvent and be beneficial to extraction.Hyperacoustic fuel factor, mechanism, cavitation effect is to be mutually related, and can give prominence to wherein a certain effect by control frequency of ultrasonic and intensity in above-mentioned scope, reduces or avoids another effect, to reach the purpose of raising effective component extraction rate.Utilize ultrasonic wave to extract, can reduce extraction time, heating-up temperature is lower simultaneously, can not destroy the effective chemical analysis in the Jehol Ligusticum Rhizome plant, raises the efficiency.
Adopt Microwave Extraction, microwave power is 50-2000w, and the time is 10min-4h.At Jehol Ligusticum Rhizome material self character, in preferred power bracket with microwave action in plant cell wall breaking, because the strong fuel factor of microwave, produce power behind the intracellular water isopolarity material absorption microwave energy, the interior temperature of born of the same parents is risen rapidly, and aqueous vapor generation pressure breaks cell membrane (wall), produces micropore or crackle, thereby make the easier stripping of intracellular matter, improved yield effectively.The Microwave Extraction time is short, and solvent load is few, the recovery rate height, and the solvent recovering rate height, the products obtained therefrom quality better, cost is low, small investment.
Adopt CO during extraction
2The supercritical extract mode is extracted, and used entrainer is an ethanol, and temperature is 25-55 ℃, and pressure is 20-40MPa.
Described drying is dried under room temperature and is got final product, and pulverizes can cross the 20-100 mesh sieve and is advisable.
The present invention also is applied to the tobacco field with described ligusticum sinense extract liquid.Concrete, ligusticum sinense extract liquid is joined in the cigarette shreds with feed liquid as cigarette, consumption is the 0.01-2% of pipe tobacco weight.
Concrete, ligusticum sinense extract liquid adds in the pipe tobacco by spray pattern.
When extracting ligusticum sinense extract liquid, can preferably ligusticum sinense extract liquid be made the medicinal extract form, in the time of in adding pipe tobacco, add pipe tobacco with table perfume (or spice) again after the dilution.
Main chemical in the ligusticum sinense extract liquid is: terpenes (comprising citrene, laurene etc.), allyl benzene derivative (comprising elemicin, myristicin etc.), phthalide analog compound (comprising cnidiumlactone, Ligustilide etc.), coumarin kind compound (comprising bergapten, scopola Roripa etc.) and other type (for example Jehol Ligusticum Rhizome ketone, Jehol Ligusticum Rhizome phenol etc.), wherein part-structure has the pharmacological effect effect, is the active ingredient of biologically active in the ligusticum sinense extract liquid.Described ligusticum sinense extract liquid is added in the cigarette shreds, in the process of burning and sucking, can obviously improve or improve the quality quality of cigarette by the peculiar chemical composition that produces, have significantly and promote the production of body fluid, cough-relieving, reduce phlegm, subtract the thorn effect, also have special delicate fragrance simultaneously, belong to the characteristic of Chinese style cigarette.
After adding ligusticum sinense extract liquid in addition, the content of harmful components in the main flume such as nicotine, tar, carbon monoxide etc. can reduce 4.5%-10%, sees table 1 for details.
| Numbering | Cigarette props up specification (mm+mm) * mm | Puff number | TPM (mg/ props up) | Actual measurement moisture content (mg/ props up) | Actual measurement nicotine amount (mg/ props up) | Actual measurement tar content (mg/ props up) | Actual measurement carbon monoxide (mg/ props up) |
| Laboratory sample | (25+59)*24.3 | 8.7 | 19.6 | 3.1 | 1.3 | 15.2 | 16.7 |
| Reference substance (normally) | (25+59)*24.3 | 8.5 | 20.5 | 3.2 | 1.4 | 15.9 | 17.9 |
| Reduction | 0.1 | 0.7 | 1.2 | ||||
| The minimizing ratio | 7.1％ | 4.5％ | 6.7％ |
The present invention has following advantage with respect to prior art:
There is the composition reservation complete extraction of pharmacodynamic feature complete in the ligusticum sinense extract liquid that the present invention extracts, method is simply with strong points, when adding in the tobacco under the prerequisite of the existing processing technology that does not change cigarette and original performance, the harmful components in the cigarette smoke have been reduced, improve smoking property of cigarette process safe and comfortableness, increase functional components the human body beneficial; Formed Chinese style cigarette simultaneously, had great importance, be easy to again be accepted, had bigger market potential by the consumer for the core technology that forms the Chinese cigarette technology with certain characteristic.
(4) specific embodiment:
Below with specific embodiment technical scheme of the present invention is described, but protection scope of the present invention is not limited thereto:
Embodiment 1
Get an amount of Jehol Ligusticum Rhizome, removal of impurities, washing, dry, take by weighing an amount of Jehol Ligusticum Rhizome, pulverize the back and cross 20 mesh sieves, in the standard of packing into the ground round-bottomed flask, add the distilled water of 5 times of weight, refluxing extraction 2 times, each 2-4h, inclining extract, washes the dregs of a decoction with water, cleaning solution and extract merge, and filter, and filtrate is reclaimed solvent in the water-bath vacuum rotary steam, obtain ligusticum sinense extract liquid medicinal extract, place in the brown bottle stored refrigerated.
With above-mentioned ligusticum sinense extract liquid medicinal extract ethanol dissolved dilution, according to the ratio of 1170g pipe tobacco adding 50.88g dilution (wherein medicinal extract is 11.7g), the dilution back evenly adds in the pipe tobacco with table perfume (or spice), places the 2h absorption under the room temperature, according to the common process cigarette.
Through smokeing panel test, the cigarette free from extraneous odour has the effect that increases fragrance matter, reduces assorted gas and excitant, promotes the production of body fluid, improves comfort level.
Embodiment 2
Get an amount of Xinjiang Jehol Ligusticum Rhizome, pulverize the back and cross 60 mesh sieves, in the port grinding bottle of packing into, add 70% ethanol of 10 times of weight, sealing was soaked 15 days, inclining soak, washs the dregs of a decoction with a small amount of solvent, and cleaning solution and soak merge, filter, filtrate is heated vacuum rotary steam and is reclaimed solvent in water-bath, concentrate and obtain ligusticum sinense extract liquid, places in the brown bottle stored refrigerated.
With above-mentioned Jehol Ligusticum Rhizome concentrate, according to the ratio of 1170g pipe tobacco adding 60.27g (concentrate is 23.4g), the dilution back evenly adds in the pipe tobacco with table perfume (or spice), places the 2h absorption under the room temperature, according to the common process cigarette.
Through smokeing panel test, the cigarette free from extraneous odour has the effect that increases fragrance matter, reduces assorted gas and excitant, promotes the production of body fluid, improves comfort level.
Embodiment 3
Get an amount of Jehol Ligusticum Rhizome, removal of impurities, washing is dried, and takes by weighing a certain amount of Jehol Ligusticum Rhizome, pulverizes the back and crosses 100 mesh sieves, in the standard of packing into the ground round-bottomed flask, adds 95% ethanol, and ultrasonic refluxing extraction 2 times, supersonic frequency are 40kHz, 50 ℃ of heating, extraction time 30min.Inclining extract, washs the dregs of a decoction with a small amount of solvent, and cleaning solution and extract merge, and filters, and filtrate decompression is revolved to steam and reclaimed solvent, obtains Jehol Ligusticum Rhizome medicinal extract, places in the brown bottle stored refrigerated.
With above-mentioned Jehol Ligusticum Rhizome medicinal extract, add the ethanol dilution of 5 times of weight, according to the ratio of 1000g pipe tobacco adding 1.0g medicinal extract, dilution evenly adds in the pipe tobacco with table perfume (or spice), places 2h under the room temperature and absorbs, according to the common process cigarette.
Through smokeing panel test, the cigarette free from extraneous odour has the effect that increases fragrance matter, reduces assorted gas and excitant, promotes the production of body fluid, improves comfort level.
Embodiment 4
Take by weighing the Jehol Ligusticum Rhizome raw material of 100g, pulverized 40 mesh sieves, the barrel of packing into is put the supercritical fluid extraction still into and is made Rhizoma Ligustici extract.Condition is as follows: extracting pressure 20Mpa, extract 50 ℃ of temperature, extraction time 2h, CO
2Flow is 28L/h, and entrainer is absolute ethyl alcohol (150mL).
When sneaking into extract in the pipe tobacco, the ratio of extract and pipe tobacco is 0.01%.
Embodiment 5
Take by weighing the Jehol Ligusticum Rhizome raw material of 100g, pulverized 40 mesh sieves, after distilled water immersion spends the night, elimination water, the flask of packing into adds 500ml ethanol as extracting solvent, puts into the Microwave Extraction device, extraction conditions is: power 500W, rated voltage 220V/50HZ, rated current 8.5A; Condensate return, middling speed stirs, and extracting temperature is 50 ℃, extraction time 30min, suction filtration, vacuum concentrated filtrate revolves to steam and reclaims solvent, obtains Rhizoma Ligustici extract medicinal extract.
When sneaking into extract in the pipe tobacco, the ratio of extract and pipe tobacco is 0.05%.
Claims (9)
1. ligusticum sinense extract liquid, it is characterized in that described extract makes by laxative remedy: will carry out drying, pulverizing through the Jehol Ligusticum Rhizome of removal of impurities, water or ethanol or both mixtures extract then, extract 5min-10h, promptly get described ligusticum sinense extract liquid after the purification.
2. ligusticum sinense extract liquid as claimed in claim 1 adopts the heating reflux type to carry out when it is characterized in that extracting, heating-up temperature is 50-105 ℃, and extraction time is 0.5-10 hour.
3. ligusticum sinense extract liquid as claimed in claim 1 is characterized in that adopting ultrasonic wave to extract, and ultrasonic frequency is 28-100KHz, and the time is 10min-6h.
4. ligusticum sinense extract liquid as claimed in claim 1 is characterized in that adopting Microwave Extraction, and microwave power is 50-2000w, and the time is 10min-4h.
5. ligusticum sinense extract liquid as claimed in claim 1 adopts CO when it is characterized in that extracting
2The supercritical extract mode is extracted, and used entrainer is an ethanol, and temperature is 25-55 ℃, and pressure is 20-40MPa.
6. ligusticum sinense extract liquid as claimed in claim 1 is characterized in that pulverizing the back Jehol Ligusticum Rhizome and can cross the 20-100 mesh sieve.
7. as the application of the described ligusticum sinense extract liquid of one of claim 1-6 in tobacco.
8. as the application of ligusticum sinense extract liquid in tobacco as described in the claim 7, it is characterized in that ligusticum sinense extract liquid is joined in the cigarette shreds with feed liquid as cigarette, consumption is the 0.01-2% of pipe tobacco weight.
9. as the application of ligusticum sinense extract liquid in tobacco as described in the claim 8, it is characterized in that ligusticum sinense extract liquid adds in the pipe tobacco by spray pattern.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101412817A CN101352258A (en) | 2008-09-04 | 2008-09-04 | Ligusticum sinense extract liquid and use thereof in tobacco |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101412817A CN101352258A (en) | 2008-09-04 | 2008-09-04 | Ligusticum sinense extract liquid and use thereof in tobacco |
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| CN101352258A true CN101352258A (en) | 2009-01-28 |
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| CNA2008101412817A Pending CN101352258A (en) | 2008-09-04 | 2008-09-04 | Ligusticum sinense extract liquid and use thereof in tobacco |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178346A (en) * | 2011-05-30 | 2011-09-14 | 昌宁德康生物科技有限公司深圳分公司 | Production method for extracting absolute oil of tobacco leaves |
| CN106349028A (en) * | 2016-08-03 | 2017-01-25 | 深圳市先康达生物科技有限公司 | Method of extracting elemicin from pepper |
| WO2018023502A1 (en) * | 2016-08-03 | 2018-02-08 | 深圳市先康达生物科技有限公司 | Method for extracting elemicin from pepper |
-
2008
- 2008-09-04 CN CNA2008101412817A patent/CN101352258A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102178346A (en) * | 2011-05-30 | 2011-09-14 | 昌宁德康生物科技有限公司深圳分公司 | Production method for extracting absolute oil of tobacco leaves |
| CN102178346B (en) * | 2011-05-30 | 2013-03-13 | 昌宁德康生物科技有限公司深圳分公司 | Production method for extracting absolute oil of tobacco leaves |
| CN106349028A (en) * | 2016-08-03 | 2017-01-25 | 深圳市先康达生物科技有限公司 | Method of extracting elemicin from pepper |
| WO2018023502A1 (en) * | 2016-08-03 | 2018-02-08 | 深圳市先康达生物科技有限公司 | Method for extracting elemicin from pepper |
| CN106349028B (en) * | 2016-08-03 | 2019-01-08 | 深圳市先康达生物科技有限公司 | A method of extracting elemicin from pepper |
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Application publication date: 20090128 |