CN101342290B - Tong bi liquid and preparation method thereof - Google Patents

Tong bi liquid and preparation method thereof Download PDF

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CN101342290B
CN101342290B CN2008102122525A CN200810212252A CN101342290B CN 101342290 B CN101342290 B CN 101342290B CN 2008102122525 A CN2008102122525 A CN 2008102122525A CN 200810212252 A CN200810212252 A CN 200810212252A CN 101342290 B CN101342290 B CN 101342290B
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CN101342290A (en
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尚守太
尚华
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Shang Shoutai
Wang Jianquan
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Abstract

The present invention relates to paralysis activating solution which is used for treating paralysis. The paralysis activating solution is prepared according to the following weight ratio: 9 to 15 portions of angelica, 8 to 12 portions of safflower, 8 to 12 portions of pawpaw, 8 to 12 portions of cassia twig, 9 to 15 portions of radix cyathulae, 8 to 12 portions of earthworm, 8 to 12 portions of dragon blood, 9 to 15 portions of bark of eucommia, 8 to 12 portions of cynamorlum, 9 to 15 portions of Chinese clematis, 15 to 25 portions of liquorice, 35 to 45 portions of Chinese tamarisk, and 8 to 12 portions of herba lycopodii. The paralysis activating solution is in particular suitable for treating the ankylosing spondylitis, proplapse of lumbar intervertebral disc, gout and other types of paralysis requiring the treatment of the Chinese medicine.

Description

Tong bi liquid and preparation method thereof
Technical field
The present invention relates to a kind of tong bi liquid, promptly a kind of medicine that is used for the treatment of arthromyodynia is particularly useful for treating the said arthromyodynias of the traditional Chinese medical science such as ankylosing spondylitis, prolapse of lumbar intervertebral disc, gout.
Technical background
Arthromyodynia is because exopathogen invasions such as human feeling's wind, cold, wet, heat cause the impatency meridians, and QI and blood can not freely be transported, thus limbs joint pain takes place, that stretch in the joint is unfavorable, influences a kind of clinical manifestation of normal activity.Arthromyodynia is traditional Chinese medical science predicate commonly used, and in conjunction with modern medicine, it can comprise such as rheumatism, rheumatoid arthritis, gout, and peripheral neuritis, sciatica, close and disease such as ankylosing spondylitis in the bone joint.Because human body is being suffered from when stating disease all with similar symptom, so the sickness rate of arthromyodynia can't accurately be added up.
Doctor trained in Western medicine is not understood because of its cause of disease as yet to this type of patient's treatment, treatment does not also have specificity, treatments such as main both at home and abroad at present application corticosteroid hormone and immunosuppressant, but treatment cycle is long, and side effect is big and uncertain therapeutic efficacy is cut, and particularly takes medicine for a long time, the intestines and stomach is had than strong stimulation, cause side effect such as sclerotin vegetables pine, femur head necrosis, after the medical treatment failure, operation is as last a kind of method that solves disease.Under severe malnutrition and weak situation, surgical effect is also undesirable in the patient many places, and the expense height, painful big narrow application range, and postoperative may be left over sequela.
Aspect the traditional Chinese medical science, mainly be to utilize acupuncture, massage and bony spur tablet for oral administration, XIAOHUOLUO WAN, loins-strengthening and kidney-invigorating bolus, Chinese herbs decoction etc., make by 27 kinds of medical materials such as Radix Angelicae Sinensis, the Radixs Astragali as disclosing a kind of Chinese patent medicine " arthromyodynia is peaceful " for the treatment of arthromyodynia among the CN1054773C, but existing Chinese medicine preparation treatment time is long, can not thoroughly effect a radical cure, or drug side effect is big, pharmaceutical formulation is excessive, take for patient for a long time and bring difficulty, and effective percentage and cure rate are lower.
Summary of the invention
The Chinese patent medicine of the treatment arthromyodynia that purpose of the present invention aims to provide a kind of good effect, have no side effect.
Technical scheme of the present invention is with reference to accounting for modern TCM Document and numerous doctor family to the achievement in research of arthromyodynia, forming through inventor's clinical research for many years again.
The present invention seeks to be achieved through the following technical solutions:
Tong bi liquid of the present invention is made by the Chinese crude drug of following weight proportion: Radix Angelicae Sinensis 9-15 part, Flos Carthami 8-12 part, Fructus Chaenomelis 8-12 part, Ramulus Cinnamomi 8-12 part, Radix Cyathulae 9-15 part, Pheretima 8-12 part, Sanguis Draxonis 8-12 part, Cortex Eucommiae 9-15 part, Herba Cistanches 8-12 part, Radix Clematidis 9-1 part, Radix Glycyrrhizae 15-25 part, Cacumen Tamaricis 35-45 part, Herba Lycopodii 8-12 part;
Tong bi liquid of the present invention is made by the Chinese crude drug of following preferable weight proportion: Radix Angelicae Sinensis 10-12 part, Flos Carthami 9-10 part, Fructus Chaenomelis 9-10 part, Ramulus Cinnamomi 9-10 part, Radix Cyathulae 10-12 part, Pheretima 9-10, Sanguis Draxonis 9-10 part, Cortex Eucommiae 10-12 part, Herba Cistanches 9-10 part, Radix Clematidis 10-12 part, Radix Glycyrrhizae 18-20 part, Cacumen Tamaricis 38-42 part, Herba Lycopodii 9-10 part;
Tong bi liquid of the present invention is made by the Chinese crude drug of following optimum weight proportioning: 10 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami; 10 parts of Fructus Chaenomeliss, 10 parts of Ramulus Cinnamomi, 15 parts of Radix Cyathulaes, 10 parts of Pheretimas, 10 parts of Sanguis Draxonis, 15 parts of the Cortexs Eucommiae, 10 parts of Herba Cistanches, 15 parts of Radix Clematidis, 20 parts in Radix Glycyrrhizae, 40 parts of Cacumen Tamariciss, 10 parts of Herba Lycopodiis;
According to the method for pharmaceutics,
Figure G2008102122525D0002101611QIETU
With with the above-mentioned raw materials medical material and other is at medicine
Figure G2008102122525D0002101555QIETU
The adjuvant of accepting is mixed and made into medicament
Figure G2008102122525D0002101538QIETU
Said any dosage form.
The preparation method of tong bi liquid.It is characterized in that this method comprises the steps:
1. with Radix Angelicae Sinensis, Fructus Chaenomelis, Ramulus Cinnamomi, Radix Cyathulae, Pheretima, Sanguis Draxonis, the Cortex Eucommiae, Herba Cistanches, Radix Clematidis, Radix Glycyrrhizae, Cacumen Tamaricis by above-mentioned weight proportion, adds water 2000-5000 weight portion and soaked 5-8 hour;
2. medical material after will soaking and water are put into boiling machine and are decocted;
3. above-mentioned medical material decocted after 1 hour, and Flos Carthami, Herba Lycopodii two flavor medical materials are put into boiling machine and decocted about 30 minutes again;
4. the rice wine of 200-300 weight portion or yellow wine or millet wine are added in the boiling machine with after medical material after the above-mentioned decoction mixes, reheat to 120 ℃, decoction is to the medicinal liquid that obtains the 1800-2000 weight portion.
Water in the preparation method of tong bi liquid in 1. is preferably 3000 weight portions, and the medicinal liquid that decocts gained in 4. is preferably 1800 weight portions.
The present invention also provides a kind of Chinese medicine composition medicine box, tong bi liquid of the present invention and a kind of capsule are wherein arranged, this capsule is to be made by the Moschus of the Semen Strychni of 0.5-2.5 weight portion and 0.5-2.5 weight portion, Semen Strychni is fried with Oleum Sesami, the peeling depilation is pulverized, the Moschus superfine grinding, and Semen Strychni, Moschus incapsulated;
In the Chinese medicine composition medicine box of treatment arthromyodynia of the present invention, the weight ratio for preparing capsular Semen Strychni and Moschus is 1.5:0.5.
The purposes of pharmaceutical composition of the present invention on the medicine of preparation treatment arthromyodynia.
The purposes of pharmaceutical composition of the present invention on the medicine of preparation treatment ankylosing spondylitis, prolapse of lumbar intervertebral disc, gout.
Usage and dosage: three months course of treatment, 1-2 each 250 milliliters of medicinal liquids of per day for adults.Children's's 2 each 125 milliliters of medicinal liquids every day that all reduce by half; Capsule 0.5 gram that oral Semen Strychni and Moschus are made when taking tong bi liquid at every turn.Morning and evening every day each 1 time after meal.
Forbidding: wine, Fructus Cucurbitae moschatae, Fructus Capsici.
Illustrate:
Cacumen Tamaricis in the medicine of the present invention is: the delicate branch and leaf of suspend plant Ramulus et Folium Tamaricis Tamarix chinensis lour..Have diffusing wind, detoxifcation, the effect of rash is used for measles without adequate eruption, rheumatic arthralgia.
The specific embodiment
Introduce the present invention below in conjunction with embodiment.
The preparation method step of medicine is as follows:
1. with Radix Angelicae Sinensis, Fructus Chaenomelis, Ramulus Cinnamomi, Radix Cyathulae, Pheretima, Sanguis Draxonis, the Cortex Eucommiae, Herba Cistanches, Radix Clematidis, Radix Glycyrrhizae, Cacumen Tamaricis by above-mentioned weight proportion, adds 20 kg water and soaked 5-8 hour;
2. medical material after will soaking and water are put into boiling machine and are decocted;
3. above-mentioned medical material decocted after 1 hour, and Flos Carthami, Herba Lycopodii two flavor medical materials are put into boiling machine and decocted about 30 minutes again;
4. 3 kilograms of millet wines add in the boiling machine with after medical materials after the above-mentioned decoction mix, reheat to 120 ℃, and decoction is to the medicinal liquid that obtains 20 kilograms, and enfeoffment becomes the aseptic packaging of one bag of 250ml;
Embodiment 2
The Chinese crude drug of following weight proportion is prepared from:
Radix Angelicae Sinensis 90 grams, Fructus Chaenomelis 80 grams, Ramulus Cinnamomi 100 grams, Radix Cyathulae 120 grams,
Pheretima 100 grams, Sanguis Draxonis 100 grams, the Cortex Eucommiae 120 grams, Herba Cistanches 100 grams,
Radix Clematidis 120 grams, Radix Glycyrrhizae 200 grams, Cacumen Tamaricis 450 grams, Flos Carthami 80 grams,
Herba Lycopodii 80 grams;
The preparation method step of medicine is poly-as follows:
1. with Radix Angelicae Sinensis, Fructus Chaenomelis, Ramulus Cinnamomi, Radix Cyathulae, Pheretima, Sanguis Draxonis, the Cortex Eucommiae, the meat desert holds, Radix Clematidis, Radix Glycyrrhizae, Cacumen Tamaricis by above-mentioned weight proportion, adds 25 kg water and soaked 6 hours:
2. medical material after will soaking and water are put into boiling machine and are decocted;
3. above-mentioned medical material decocted after 1 hour, and Flos Carthami, Herba Lycopodii two flavor medical materials are put into boiling machine and decocted about 30 minutes again;
4. 2.5 kilograms of yellow wine add in the boiling machine with after medical materials after the above-mentioned decoction mix, reheat to 120 ℃, and decoction is to the medicinal liquid that obtains 18 kilograms, and enfeoffment becomes the aseptic packaging of one bag of 250ml.
Embodiment 3
The Chinese crude drug of following weight proportion is prepared from:
Radix Angelicae Sinensis 120 grams, Fructus Chaenomelis 120 grams, Ramulus Cinnamomi 80 grams, Radix Cyathulae 90 grams,
Pheretima 90 grams, Sanguis Draxonis 80 grams, the Cortex Eucommiae 90 grams, Herba Cistanches 80 grams,
Radix Clematidis 90 grams, Radix Glycyrrhizae 250 grams, Cacumen Tamaricis 350 grams, Flos Carthami 120 grams,
Herba Lycopodii 120 grams,
The preparation method step of medicine is as follows:
1. with Radix Angelicae Sinensis, Fructus Chaenomelis, Ramulus Cinnamomi, Radix Cyathulae, Pheretima, Sanguis Draxonis, the Cortex Eucommiae, Herba Cistanches, Radix Clematidis, Radix Glycyrrhizae, Cacumen Tamaricis by above-mentioned weight proportion, adds 30 kg water and soaked 7 hours;
2. medical material after will soaking and water are put into boiling machine and are decocted;
3. above-mentioned medical material decocted after 1 hour, and with Flos Carthami, Herba Lycopodii two flavor medical materials are put into boiling machine and decocted about 30 minutes again;
4. 2 kilograms of rice wine adds in the boiling machine with after medical materials after the above-mentioned decoction mix, reheat to 120 ℃, and decoction is to the medicinal liquid that obtains 19 kilograms, and enfeoffment becomes the aseptic packaging of one bag of 250ml.
Drug therapy clinical case of the present invention
The inventor is engaged in ankylosing spondylitis research smelting treatment work 18 years, is to show medicament of the present invention to sick effects for the treatment of such as ankylosing spondylitises,
Figure G2008102122525D0005101904QIETU
Imitate careful clinical statistics, statistics shows that in 100 routine patients with ankylosing spondylitis of inventor's treatment, 85 examples are cured, 20 routine produce effects, and 5 examples are invalid, and cure rate can reach 85%.And the male is more than the women among the above-mentioned patient, minimum 18 years old of patient, and maximum more than 40 year old, the mean age about 30: in 10 routine prolapse of lumbar intervertebral disc patients of inventor's treatment, 88 examples were cured, 10 routine produce effects, 2 examples are invalid, and cure rate reaches 88%.50 examples in inventor's treatment
Figure G2008102122525D0005102008QIETU
,
Figure G2008102122525D0005102020QIETU
,
Figure G2008102122525D0005102044QIETU
, cure rate reaches 80%.
Be 12 model cases in the clinical practice of the present invention below:
1, Chu Chenchen, man, 13 years old, the hair village, Taikang County, Henan Province village people.Everyday come my to go to a doctor by the rheumatism training April 8 calendar year 2001, infant can not be walked when coming, the knee joint red and swollen heat pain, and spirit is poor, inappetence, pale complexion is accompanied hyperpyrexia (T:38.5 ℃)
The main suit: waist hip, hardness and pain 1 year are surplus, to the Zhengzhou City, Zhoukou City's various big hospital fails to respond to any medical treatment rapid pulse; Tongue fur: Huang, have a medical check-up: lift the extruding of lower limb test (+) " 4 " test pelvis, separation test (+) difficulty of bending over, squat down.
The laboratory: routine blood test, hematochrome (IIb) 8g, erythrocyte is normal, lymphocyte (0) 7.5, rheumatism (ASO) rheumatoid factor (RF) () feminine gender, HRA (+) positive, erythrocyte sedimentation rate (ESR): 90mm/h.
The X line is looked into: lumbar vertebra physiological bending, curved straight, two sacroiliac joint edge blurrys, slightly sclerosis and small erosion pathological changes.
Diagnosis: Western medicine diagnose is: the ankylosing spondylitis II phase, tcm diagnosis is: rheumatism involving the bone
Through taking medicine tong bi liquid after January, pain relief.After March, body is looked into, and both legs praise 60, and the facility of squatting down can be left the bed and be walked, erythrocyte sedimentation rate: 40mm/h, and hematochrome is normal, and T:37.5 ℃, after the half a year of taking medicine, symptom all disappears, and follows up a case by regular visits to not recurrence in 7 years.
2, Pan Changhai, the man, 34 years old, Taikang County, Henan Province king collected the village people.In in October, 2000 my rheumatism training go to a doctor, patient's neck is stiff tetanic, bow-backed.The main suit: neck, waist, hip, two knee joint pain, show effect repeatedly 10 years surplus, to hospitalize in many ways, eat folk prescription and drink medicated wine, commentariess on classics of not getting better, the time weight when light.
Have a medical check-up: both legs are praised difficulty, and the positive pelvis extruding of " 4 " test separates positive
Reach the standard grade: intervertebral disc space generation calcification, syndesmophyte form and make the adjacent vertebral bodies Colaesce form bone bridge between vertebral body, are the most characteristic bamboo spine, and the sacrum ilium merges fully
The laboratory: routine blood test is normal, and the mixed factor of rheumatism class wind is normal.
Diagnosis: ankylosing spondylitis (later stage)
Through obeying: tong bi liquid, pain takes a turn for the better after 1 year, takes care of oneself, and the state of an illness did not recur after stable disease was taken medicine 2 years, followed up a case by regular visits to over 8 years the light work ability of taking care of oneself.
3, mass troops the soldier, the woman, the student, 15 years old, the Taikang County, Henan Province accorded with careless people from building.On February 4th, 2003, by the agency of one comes me section to go to a doctor, and spirit was poor when patient came, inappetence, pale complexion, companion's low grade fever (T:37.5 ℃)
Figure G2008102122525D0006075941QIETU
Number
Figure G2008102122525D0006102233QIETU
, yellow greasy
Main suit: do not have inducement before 3 years.Suddenly two knee joint swelling pains, local pyrexia, each big joint of waist hip gradually, hardness and pain increases the weight of, and is heavy when light during to local hospitalize, and the back is to the Zhengzhou City, Beijing's various big hospital, the commentaries on classics of not getting better after treatment.
Have a medical check-up: both legs are praised examination
Figure G2008102122525D0006080019QIETU
(positive) "
Figure G2008102122525D0006080034QIETU
" test pelvic compression and separation test (positive),
The X line, the lumbar vertebra physiological bending disappears, and two sacroiliac joint edge blurrys are slightly hardened and small erosion pathological changes, and articular cavity narrows down, the swelling of knee joint inflammatory, intracavity has hydrops.
The laboratory: numeration of leukocyte raises, and lymphocyte increases, slight basin blood, erythrocyte sedimentation rate 85mm/h, rheumatism rheumatoid factor negative, the HRA-B27 positive.
Western medicine diagnose is: ankylosing spondylitis tcm diagnosis: rheumatism involving the bone
Through taking: tong bi liquid is after January, and double knee joint swelling disappears, and ache all over the body alleviates, the bimester after, patient tells: the swelling of stiffness of the waist pain alleviates, during chemical examination erythrocyte sedimentation rate 50mm/h, and T:36.8 ℃, after March, patient's waist is stiff, the ache all over the body complete obiteration, and T:36 ℃, during erythrocyte sedimentation rate 10mm/h, stable disease.Follow up a case by regular visits to not recurrence in 5 years.
4, Zhu Liang: man, 17 years old, student, people from Zhecheng County, Henan Province.
The Nikkei people introduced me section to go to a doctor Mays 19 in 2003, and spirit is poor when coming, inappetence, pale complexion, companion's low grade fever (T:38 ℃) arteries and veins: loud number, tongue fur: white greasy.
Main suit: after the flu, find myasthenia of limbs, cold perspiration the year before. the bimester after two knee joints, the swollen ankles burning pain, waist is stiff, in local hospital, quiet, penicillin+hormone, continuously quiet 15 days, take a turn for the better, recurrence once more after the drug withdrawal, the back is to Zhengzhou large hospital hospitalization, and is heavy when light during the state of an illness.
Have a medical check-up: it is positive that both legs are raised test, the pelvic compression and separation test positive " 4 ", and test is positive.
The X line: the lumbar vertebra physiological bending becomes straight, and two hip ilium edge blurrys are unclear, and articular cavity narrows down.
The laboratory: numeration of leukocyte is normal, and percentage of lymphocyte has increase slightly, hematochrome 8g, and erythrocyte sedimentation rate 100mm/h, the serum creatine phosphokinase raises, the serum rheumatoid factor (SRF) feminine gender
Diagnosis: ankylosing spondylitis (renal deficiency type)
Through the clothes tong bi liquid, sb.'s illness took a favorable turn after January, the bimester after two knee joint ankle swelling disappear, waist is stiff to be had slightly and alleviates, after April, light from head to foot.The complete obiteration of expanding of painful carbuncle, T:36 ℃, hematochrome 10g, take continuously tong bi liquid after two courses of treatment the state of an illness recover fully normally, follow up a case by regular visits to and recur for the year ends 5.
5, Zhang Defu, man, 12 years old, Ma Chang township, Taikang County, Henan Province big Zhang village people from village.
Come me section to go to a doctor June 24 nineteen ninety, have infant in arms when coming and enter house, spirit is poor, and mind is clear, appetite
Figure G2008102122525D0007080104QIETU
Shake, pale complexion,
Figure G2008102122525D0007080113QIETU
Have thermotropism (T:38.5 ℃) generation to tell: before 2 years, play the unexpected left side pain that has a pain in the leg morning behind the rain, can not
Figure G2008102122525D0007080123QIETU
To local clinic
Figure G2008102122525D0007080130QIETU
Calcium deficiency is failed to respond to any medical treatment, and along with the right side has a pain in the leg pain unbearably, father and mother are being with the county town hospital admission, quiet of hospitalization
Figure G2008102122525D0007102339QIETU
Hormone 10 days is surplus, disease relapse after the drug withdrawal, and I go to a doctor at section afterwards
Have a medical check-up: both legs are raised the positive, and knee joint is stretched the extruding of inconvenience " 4 " test pelvis, the separation test positive.
The X line: the lumbar vertebra physiological bending disappears, hipbone deformity double knee joint gap turn narrow, and the sclerosis of sacroiliac joint both sides, edge blurry is unclear
The laboratory is looked into: routine blood test is normal, erythrocyte sedimentation rate 110mm/h, rheumatism rheumatoid factor negative, the HRA-B27 positive.
Diagnosis: ankylosing spondylitis (II phase)
Through the clothes tong bi liquid, after March, the state of an illness is clearly better, and it is normal that two knee joints are stretched Qu Jiben, is holding up the crutch can be movable. and after half a year, the rumpbone malformation is straight, 60 degree of bending over to squat down, the heavy 25mm/h that has a blood test, T:36.8 ℃, check after three months continue clothes: chemical examination, all are normal for the X line.
Introduce through father patient, granddad patient, uncle have bend over, bow-backed symptom, frequent lumbago and skelalgia, thus assert that the patient has family's medical history, after obey three months tong bi liquids again, follow up a case by regular visits to over 8 years the end and recur, now attend Taikan senior middle school second grade.
6, Li Yongheng, man, 46 years old, area just outside a city gate people from town, Taikang County, Henan Province.In calendar year 2001 December came institute to go to a doctor on the 5th, two people lift to my section's clinic when coming, the right side has a pain in the leg pain unbearably.
The main suit: calendar year 2001 December helped others to lift bed on 2nd, overexert, cause flank pain, right lower extremity pain gradually, can't sleep existing two days two nights, beats pain killer injection in the clinic and do not slow and separate, and listens others to introduce my section to go to a doctor, spirit is poor when coming, general weakness.
Have a medical check-up: right lower limb is praised 30 degree, and pain is stood up difficulty unbearably.
The laboratory: routine blood test is normal, the rheumatism factor negative.
Look into CT scan: L: 3,4,5 intervertebral disc root compressions.
Diagnosis: prolapse of lumbar intervertebral disc.
Through clothes tong bi liquid after January, clinical symptom disappearance, the time and the lower limb acid precipitation, after ten days, the symptom complete obiteration is followed up a case by regular visits to 7 years without any the lumbago and skelalgia symptom continue the clothes tong bi liquid.
7, Li Jinglan, woman, 53 years old; Lao Zhong people from town, Taikang County, Henan Province.On March 4th, 2005, come me section to go to a doctor, two people lifted into my section when the patient came.
Main suit: do not have inducement before 5 years, get up morning and find the lower limb skelalgia, look into CT to the People's Hospital, Huaiyang County, Henan Province and find: the L5/S1 intervertebral disc prolapse.In the physical therapy acupuncture of local hospital, massage, the state of an illness is not felt any better, and the back is to the treatment of Zhoukou Prefecture, Henan Province hospital surgical, and sb.'s illness took a favorable turn in the treatment back, and transference cure is said when patient comes, and does not know what inducement, Flank pain and lower limb pain when putting
Have a medical check-up: the straight-leg raising test positive, the patient lies on the back, and the trouble limb stretches upwards praises, and radiating pain occurs.The neck test, lying on the back places rear pillow part with hands, makes head and neck anteflexion, waist or leg pain occur.
MRI looks into: lumbar physiological-curvature exists, and the L5/S1 intervertebral disc is short
Figure G2008102122525D0008080233QIETU
Also exceed the vertebral body trailing edge backward causes corresponding dural sac leading edge pressurized to 2 signals, and abnormal signal is seen at the end in the canalis spinalis
Diagnosis: L5/S1 intervertebral disk hernia
Through obeying tong bi liquid after January, straight lower limb is praised radiating pain and is disappeared, long-time walking, and lower limb have the acid precipitation sense, and continue and obeyed tong bi liquid three months, the complete obiteration of pain acid precipitation, all are normal, follow up a case by regular visits to not recurrence in 3 years.
8, Chen Huiyan, the man, 36 years old, the Taikang County, Henan Province collected the village people clearly, on April 30th, 1997, came me section to go to a doctor, and hunchback when the patient comes becomes waist, turns round difficulty, and cervical region is tetanic.
The main suit: neck, waist, the back of the body, stiff tetanic no mobility 5 years are surplus, and grandfather patient, father are similar symptoms, once arrive Zhengzhou, the diagnosis of Beijing various big hospital, family history sex-controlled inheritance disease, and the expert does not have good therapeutic scheme.
Body is looked into: two lower limbs stretch praises difficulty, the extruding of " 4 " test pelvis, the separation test positive.
The X line: lumbar physiological-curvature becomes straight, is little joint between " change of ring sample " square vertebra, thoracic vertebra and cervical vertebra, intervertebral disc space generation calcification.
The laboratory is looked into: routine blood test is normal, erythrocyte sedimentation rate 25mm/h, rheumatism rheumatoid factor negative, the HRA-B27 positive.
Diagnosis: ankylosing spondylitis
Through obeying tong bi liquid 6 months.The patient tells the stiff improvement of pain relief, obeys the tong bi liquid stiff symptom complete obiteration of pain in 6 months again.Follow up a case by regular visits to not recurrence in 10 years.
9, Chen Jiong, the man, 15 years old, the Taikang County, Henan Province collected the village people clearly.Come my section to seek medical advice on February 20th, 1998, spirit was poor when infant came, and mind is clear, inappetence, face light yellow complexion.
Main suit: do not have inducement the year before, rising morning leaves the bed suddenly feels Carbuncle of heel, pain relief after anesthesia needle is made in local clinic, after January, right knee joint swelling, heating, companion's low grade fever (T:37.5 ℃) is quiet antiinflammatory pin+hormone in local clinic, connect and drip a week, heating take a favorable turn slightly, and drug withdrawal two all state of an illness recur once more, arteries and veins: count tongue fur accurately: white.
Have a medical check-up: both legs are praised difficulty, " 4 " test, pelvis extruding, the separation test positive.
The X line: the lumbar vertebra physiological bending exists, and the sacroiliac joint marginal membrane is stuck with paste, and hydrops is arranged in the knee joint cavity.
The laboratory is looked into: routine blood test is normal, erythrocyte sedimentation rate 60mm/h, rheumatism rheumatoid factor negative, the HRA-B27 positive.
Be diagnosed as: ankylosing spondylitis (in early days)
Through the clothes tong bi liquid, right knee joint swelling disappears after March, erythrocyte sedimentation rate 30mm/h, serve on one month after, not recurrence in 8 years is followed up a case by regular visits in the normal symptom complete obiteration of erythrocyte sedimentation rate, work in Guangzhou now.
10, Han Jun, the woman, 18 years old, Taikang County, Henan Province king collected the village people.The patient comes me section to go to a doctor March 21 calendar year 2001, and spirit is poor when coming, inappetence, and companion's low grade fever (T:37 ℃) pale complexion, arteries and veins: number is loud, tongue fur: yellow greasy.
The main suit: the bimester before, at Guangzhou province Dongguan City because of not sleeping the night of working overtime, find right knee joint swelling pain when have a meal the next morning, channel, force on, obey continuously treatment one month of antibiotic, swelling disappears, drug withdrawal after 1 month suddenly double knee joint swell and ache, generate heat, two hip pain, waist is stiff, stands up difficulty, can not walk, to the commentaries on classics of not getting better of the People's Hospital, Taikang County hospitalization two weeks, arrive my upon somebody's introduction and section go to a doctor.
Have a medical check-up: both legs are praised difficulty, and it is unfavorable that the positive two knee joint songs of pelvis extruding separation " 4 " test are stretched.
The X line: the lumbar vertebra physiological bending exists two sacroiliac joint films to stick with paste, and hydrops is arranged in the knee joint cavity.
The laboratory is looked into: routine blood test, leukocyte increases, erythrocyte sedimentation rate 80mm/h, hematochrome 8g, the rheumatism factor rheumatoid factor positive, the HRA-B27 positive.
Diagnosis: ankylosing spondylitis
Through obeying tong bi liquid three months, the stiffness of the waist alleviates, and hydrarthrosis reduces, and body temperature T:36.5 ℃, three months tong bi liquid state of an illness of clothes that continue are recovered normally to follow up a case by regular visits to over 8 years and do not recur fully.
11, Wang Zaisong, the man, 34 years old, poplar mausoleum, Taikang County, Henan Province village people came me section to go to a doctor on April 25th, 1998, and spirit was poor when the patient came, and mind is clear, inappetence, physique is become thin, green around the gills, T:38.5 ℃ of companion's hyperpyrexia, arteries and veins: number is loud; Tongue fur: yellow greasy.
The main suit: there was not inducement before 12 years, unexpected neck, stiffness of the waist pain, two subsides of forcing in local clinic are not felt any better, get to the clinic again indometacin+hormone+antibiotic medicine serve on ten days surplus, pain takes a turn for the better, disease relapse after the drug withdrawal, arrive Zhengzhou again, hospitalization is heavy when light during the state of an illness, recently the flu back state of an illness increases the weight of, the waist hip occurs, the stiff pain of two knee joints increases the weight of, and stands up difficulty, can't take care of oneself, come my section upon somebody's introduction.
Have a medical check-up: both legs are praised difficulty, and " 4 " test is positive, the pelvic compression and separation test positive, Wry Neck, two knee joint swelling.
The X line is looked into: the lumbar vertebra physiological bending disappears, and being " square vertebra " has bone degeneration, two sacroiliac jointes that destruction is in various degree arranged, and edge engrail osteosclerosis is closed the narrow disappearance of internode, and the broadening of knee joint gap has hydrops.
Chemical examination is looked into: routine blood test is normal, erythrocyte sedimentation rate 80mm/h, hematochrome (Fb) 8g rheumatism (ASO) rheumatoid factor (RF) feminine gender, HRA-B27 (positive)
Be diagnosed as: ankylosing spondylitis (II phase)
Through clothes tong bi liquid three months,
Figure G2008102122525D0010102513QIETU
(ESR) 25mm/h, IIb10g, rheumatism (ASO) rheumatoid factor (RF) feminine gender.Arthroedema disappears, and obey tong bi liquid life in three months again and can take care of oneself, the light work ability, the whole body activity is freely.Follow up a case by regular visits to 10 years state of an illness and do not recur, work in Beijing now.
12, the little duty of shutting out, man, 36 years old, Taikang County, the Henan Province cadre of personnel bureau.Came my section to go to a doctor in 1999 No. 12 30 days, when the patient comes spirit can, mind is poor, half low grade fever (T:37 ℃).
The main suit: no inducement plays that unexpected toes swollen joint is painful, local rubescent speed is gone to a doctor to county people's hospital morning before 2 months, is diagnosed as the defeated promoting blood flow and remove blood stasis drug of gout, and sb.'s illness took a favorable turn after ten days to obey colchicine.Heavy when light during the state of an illness after the drug withdrawal.Usual happiness food pluck, acidic beverages came me section to go to a doctor in No. 12 30 days.Patient's obesity also has hypertension, hyperlipidemia.
Body is looked into: right foot first toes redness and swelling of joints heat is painful.
The X line: ossa articularia cortex destruction, epiphysis cortex light transmission are damaged.
Chemical examination is looked into: routine blood test is normal, and rheumatism rheumatoid factor is normal, and blood uric acid is greater than 385.
Diagnosis: gout
Through the clothes tong bi liquid after course of treatment, the red and swollen disappearance.State of an illness recovery from illness after two courses of treatment.Follow up a case by regular visits to not recurrence in 11 years.

Claims (10)

1. medicine for the treatment of arthromyodynia is characterized in that being being made by the Chinese crude drug of following weight proportion: Radix Angelicae Sinensis 9-15 part, Flos Carthami 8-12 part, Fructus Chaenomelis 8-12 part, Ramulus Cinnamomi 8-12 part, Radix Cyathulae 9-15 part, Pheretima 8-12 part, Sanguis Draxonis 8-12 part, Cortex Eucommiae 9-15 part, Herba Cistanches 8-12 part, Radix Clematidis 9-15 part, Radix Glycyrrhizae 15-25 part, Cacumen Tamaricis 35-45 part, Herba Lycopodii 8-12 part.
2. medicine as claimed in claim 1 is characterized in that being being made by the Chinese crude drug of following weight proportion: Radix Angelicae Sinensis 10-12 part, Flos Carthami 9-10 part, Fructus Chaenomelis 9-10 part, Ramulus Cinnamomi 9-10 part, Radix Cyathulae 10-12 part, Pheretima 9-10 part, Sanguis Draxonis 9-10 part, Cortex Eucommiae 10-12 part, Herba Cistanches 9-10 part, Radix Clematidis 10-12 part, Radix Glycyrrhizae 18-20 part, Cacumen Tamaricis 38-42 part, Herba Lycopodii 9-10 part.
3. medicine as claimed in claim 1 is characterized in that being being made by the Chinese crude drug of following optimum weight proportioning: 10 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 10 parts of Fructus Chaenomeliss, 10 parts of Ramulus Cinnamomi, 15 parts of Radix Cyathulaes, 10 parts of Pheretimas, 10 parts of Sanguis Draxonis, 15 parts of the Cortexs Eucommiae, 10 parts of Herba Cistanches, 15 parts of Radix Clematidis, 20 parts in Radix Glycyrrhizae, 40 parts of Cacumen Tamariciss, 10 parts of Herba Lycopodiis.
4. the preparation method as the medicine of claim 1,2 or 3 described treatment arthromyodynias is characterized in that this method comprises the steps:
1. with Radix Angelicae Sinensis, Fructus Chaenomelis, Ramulus Cinnamomi, Radix Cyathulae, Pheretima, Sanguis Draxonis, the Cortex Eucommiae, Herba Cistanches, Radix Clematidis, Radix Glycyrrhizae, Cacumen Tamaricis by above-mentioned weight proportion, adds the water of 2000-5000 weight portion, soaked 5-8 hour,
2. medical material after will soaking and water are put into boiling machine and are decocted,
3. above-mentioned medical material decocted after 1 hour, and Flos Carthami, Herba Lycopodii two flavor medical materials are put into boiling machine and decocted about 30 minutes again,
4. the rice wine of 200-300 weight portion or yellow wine or millet wine are added in the boiling machine with after medical material after the above-mentioned decoction mixes, reheat to 120 ℃ decocts to the medicinal liquid of 1800-2000 weight portion, promptly.
5. preparation method as claimed in claim 4, the water in it is characterized in that 1. is 3000 weight portions, the medicinal liquid that decocts gained in 4. is 1800 weight portions.
6. drug products as the treatment arthromyodynia of claim 4 or the preparation of 5 described preparation methoies.
7. Chinese medicine composition medicine box for the treatment of arthromyodynia, its drug products and a kind of capsule by the described treatment arthromyodynia of claim 6 is formed, this capsule is to be made by the Moschus of the Semen Strychni of 0.5-2.5 weight portion and 0.5-2.5 weight portion, Semen Strychni is fried with Oleum Sesami, the peeling depilation is pulverized, the Moschus superfine grinding, and Semen Strychni, Moschus incapsulated.
8. the Chinese medicine composition medicine box of a treatment arthromyodynia as claimed in claim 7, the weight ratio that wherein prepares capsular Semen Strychni and Moschus is 1.5: 0.5.
9. the purposes of each described Chinese medicine composition medicine box on the medicine of preparation treatment ankylosing spondylitis, prolapse of lumbar intervertebral disc, gout among the medicine of each described treatment arthromyodynia or the claim 7-8 among the claim 1-3.
10. the purposes of each described Chinese medicine composition medicine box on the medicine of preparation treatment arthromyodynia among the medicine of each described treatment arthromyodynia or the claim 7-8 among the claim 1-3.
CN2008102122525A 2008-09-08 2008-09-08 Tong bi liquid and preparation method thereof Expired - Fee Related CN101342290B (en)

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CN102224973A (en) * 2011-06-17 2011-10-26 童作模 Socks capable of preventing and curing gout by wearing to sleep
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CN108114253A (en) * 2017-12-29 2018-06-05 李汝清 A kind of herbal fumigation agent for treating ankylosing spondylitis and its application method
CN110101822A (en) * 2019-06-14 2019-08-09 李海龙 A kind of traditional Chinese medicine secret recipe for treating Bi condition, heumatism disease

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