CN101331949A - Sports nutrient replenisher for promoting muscle synthesize - Google Patents
Sports nutrient replenisher for promoting muscle synthesize Download PDFInfo
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- CN101331949A CN101331949A CNA2008101167567A CN200810116756A CN101331949A CN 101331949 A CN101331949 A CN 101331949A CN A2008101167567 A CNA2008101167567 A CN A2008101167567A CN 200810116756 A CN200810116756 A CN 200810116756A CN 101331949 A CN101331949 A CN 101331949A
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Abstract
The invention relates to a sports nutritional supplement which promotes the muscle synthesis and comprises the main components of the compound of zinc and magnesium and creatine compound. The sports nutritional supplement which promotes the muscle synthesis can effectively promote the secretion of a plurality of synthetic hormones of human body, has marked effect of muscle increase combining with certain exercise stimulation and can meet the requirements of people doing exercises and fitness and body building.
Description
Technical field
The present invention relates to a kind of replenishers, particularly relate to the synthetic sports nutrient replenisher of a kind of short muscle.
Background technology
Almost the sportsman of any one sports events needs strength building, and muscle is the organ that produces strength, want to reach the effect of strength building, at first need to increase the degree of enclosing of muscle, the same expectation of vigorous and graceful player has flourishing muscle volume and muscle lines clearly.Want to make muscle to obtain increasing, diligent and the training of science is essential, simultaneously, eat some safe and effective nutritious supplementary pharmaceuticals in right amount, can help to train to reach the effect of getting twice the result with half the effort.
It is existing that to increase the flesh product mainly be pure creatine powder and protein powder, wherein creatine mainly is to create conditions for the synthetic of myocyte, protein is then as the synthesis material of myogen, the two all belongs to external cause for the synthetic process of muscle, though have certain effect, can enter plateau after additional a period of time, effect is no longer obvious, this is that the internal cause here refers to the synthetic hormone of human body self because be subjected to the restriction of internal cause.
Summary of the invention
The object of the invention provides the synthetic sports nutrient replenisher of a kind of short muscle, is intended at the prior art deficiency, for the sportsman and the fitness and body-building crowd of professional domain increases muscle, solves the problem of strength deficiency.
The sports nutrient replenisher that short muscle provided by the invention is synthetic, its main component and by weight proportioning be:
20～400 parts on zinc (by zinc ion weight)
40～1000 parts in magnesium (by magnesium ion weight)
2000～10000 parts of creatine compounds (by creatine weight).
Preferably, its main component and by weight proportioning be:
40～300 parts of the compounds of zinc (by zinc ion weight)
80～600 parts of the compounds of magnesium (by magnesium ion weight)
4000～8000 parts of creatine compounds (by creatine weight).
More preferably, its main component and by weight proportioning be:
50 parts of the compounds of zinc (by zinc ion weight)
100 parts of the compounds of magnesium (by magnesium ion weight)
6000 parts of creatine compounds (by creatine weight).
The compound of zinc is selected from one or more in zinc acetate, zinc carbonate, zinc chloride, zinc citrate, zinc gluconate, zinc lactate, zinc sulfate, the zinc oxide.
The compound of magnesium is selected from one or more in magnesium carbonate, magnesium chloride, magnesium citrate, magnesium gluconate, magnesium glycerophosphate, magnesium lactate, magnesia, phosphoric acid magnesium salts, magnesium sulfate, the Magnesium Asparticum.
Creatine compound is selected from one or more in a hydration creatine and creatine hydrochloride, creatine malate, creatine citrate, the creatine ethyl ester, the raw material of wherein employed creatine and/or its compound can be the quick-releasing type product, also can be the spacetabs type product.
Creatine is a kind of natural amino acid in the human body, and body weight is in the human body of 70kg, creatine (comprising free creatine and phosphocreatine) the about 120g of storage capacity.The mankind mainly obtain required creatine by meals, the poultry meat and the flesh of fish are the good sources of creatine, as containing the 1g creatine of having an appointment in the 250g red meat, the people can take in the about 1g of amount of creatine every day by meals, in addition, liver, kidney, pancreas can utilize glycine, arginine and methionine to synthesize a small amount of creatine.
As far back as eighties of last century seventies, creatine just is used to treat diseases such as muscular atrophy, eighties of last century beginning of the nineties, begin as sports nutrient replenisher, and its consumption figure increases rapidly.Additional creatine not only can increase phosphocreatine concentration in the muscle, also can promote the synthetic of ATP simultaneously, thereby improves the quick contractility of muscle, raising speed, endurance and explosive force.And, taking creatine and have and significantly increase the flesh effect, the myocyte is when absorbing creatine, because the increase of cellular hydration state makes cell-volume enlarge, increases the aggregate velocity of myogen, has promoted the growth of new flesh.Edible creatine can't cause the problem of the excitant positive.
As everyone knows, animal and human's class lacks zinc and causes growth retardation, and zinc supplementation can reverse.In fact, for sport people, zinc also is a kind of very welcome replenishers, and this is because zinc supplementation can promote the growth of muscle, improves the quality of muscle.Discover that zinc supplementation can promote the secretion of testosterone hormone in the body, testosterone is very important a kind of short synthetic hormone in the human body, is that muscle growth is requisite.In addition, zinc supplementation can also increase hemoglobin and erythrocytic quantity in the body, and zinc also helps to remove the free radical in the body, and these 2 also is very important for sport people.
Magnesium is a large amount of a kind of mineral matter elements that exist in the human body, is the activator of plurality of enzymes in the body, to the excitement levels of keeping muscle, preventing to knot plays a very important role.Similar with zinc, magnesium can promote the secretion of multiple synthetic hormone in the body equally, therefore helps muscle growth.Magnesium also helps absorption, the utilization of creatine, and this is that magnesium plays crucial effects in this process because creatine will pass through the effect of a series of biological respinse competence exertion after entering human body.
The sports nutrient replenisher that short muscle of the present invention is synthetic mainly contains zinc, magnesium and creatine.Creatine, zinc, magnesium, be the synthetic nutriments of three kinds of important promotion muscle, its principle is different, and zinc, magnesium mainly are to promote the synthetic of muscle by the secretion that stimulates synthetic hormone, creatine is by impelling the myocyte to keep hydration status, and is that the synthetic of muscle creates conditions.The three has certain synergy.Therefore, this patent can also contain other micro-nutrients with the three by the rational proportion collocation together.
The synthetic sports nutrient replenisher of short muscle of the present invention can add micronutrient, such as mineral matter, vitamin or amino acid.In general, each consumption is: 400～6000 parts in potassium, 400～6000 parts in sodium, 100～1500 parts of calcium, VB14～60 part, 3～50 parts of vitamin B2s, 3～50 parts of vitamin B6s, 20～300 parts in nicotinic acid, 2000～20000 parts of leucines, 1000～10000 parts of isoleucines, 1500～15000 parts of valines.
The short muscle of the present invention synthetic the preparation method of sports nutrient replenisher, be to adopt each composition to mix by proportioning, according to pharmacy conventional formulation method, can be prepared into various pharmaceutically acceptable formulations such as pulvis, capsule, granule, tablet.
Used auxiliary material is a conventional auxiliary material pharmaceutically in the wherein said formulation, as select for use starch, dolomol, cellulose, silica, talcum powder, lactose, dextrin etc. as filler, glidant or binder, its preparation method is the conventional method on the galenic pharmacy.
The use of arranging in pairs or groups of the synthetic sports nutrient replenisher of the short muscle of the present invention, composition by these two kinds on zinc, magnesium being helped lend some impetus to the synthetic hormone secretion and creatine has remedied and increases the flesh product in the past and only emphasize external cause, and ignores the shortcoming of internal cause.Can promote the secretion of the multiple synthetic hormone of human body effectively, cooperate certain exercise to stimulate, have and significantly increase the flesh effect, can satisfy sport people and fitness and body-building crowd's needs.
The specific embodiment
Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.
Embodiment 1
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc citrate 67 grams (zinc ion 20g), magnesium chloride 160 grams (magnesium ion 40g), spacetabs type one hydration creatine 9.1kg (creatine 8kg), sodium chloride 1025g (sodium ion 400g), potassium chloride 770g (potassium ion 400g), granulated sugar powder 14kg, citric acid 250g.
Its preparation process is as follows: take by weighing each component by above-mentioned weight, pulverize the back and cross 80 mesh sieves, mix, divide the bottle of packing into, get pulvis.
Embodiment 2
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc lactate 182g (zinc 40g), magnesium gluconate 566g (magnesium 30g), magnesium sulfate 250g (magnesium 50g), creatine hydrochloride 2556g (creatine 2000g), VB14 g, vitamin B2 3g, vitamin B6 3g, talcum powder 25g.
Its preparation process is as follows: take by weighing each component by above-mentioned weight, pulverize, mixing is poured capsule into and is filled in the mould, and the powder of the capsule surface of scraping gets capsule.
Embodiment 3
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc gluconate 2.34kg (zinc 300g), Magnesium Asparticum 5.45kg (magnesium 600g), dicreatine malic acid salt 5.71kg (creatine 4000g), sodium chloride 15.3kg (sodium 6000g), potassium chloride 11.5kg (potassium 6000g), calcium chloride 4.16kg (calcium 1500g), vitamin B6 50g, nicotinic acid 300g, starch 6kg, silica 60g.
Its preparation process is as follows: take by weighing each component (except the silica) by above-mentioned weight, pulverize, mixing is made adhesive with 80% ethanolic solution, makes softwood, the wet grain of the 20 mesh sieve systems of crossing.The grain that will wet placed 50～60 ℃ of oven dryings 3～4 hours, crossed the whole grain of 18 mesh sieves, must do particle, and add silica and make lubricant, mixing, compressing tablet in tablet press machine gets tablet.
Embodiment 4
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc acetate 4.27kg (zinc 400g), magnesium lactate 18.9kg (magnesium 1000g), dicreatine malic acid salt 14.3kg (creatine 10000g), leucine 6k, isoleucine 3kg, valine 4.5kg, dextrin 45kg.
Its preparation process is as follows: take by weighing each component by above-mentioned weight, pulverize, mixing is made adhesive with 80% ethanolic solution, makes softwood, and softwood is waved the granulator granulation through the YK-160 type of 12 mesh sieve eyes, gets wet granular.After treating alcohol volatilization fully, material is placed the multi-functional granulator of DPL-30 type,, finished product moisture is controlled in 5% about one hour of 50 ℃ of fluidized dryings.Sieve, whole grain gets granule.
Embodiment 5
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc gluconate 390g (zinc 50g), magnesium carbonate 350g (magnesium 100g), a hydration creatine 6.82kg (creatine 6000g), dextrin 7kg, white sand Icing Sugar 5kg, acesulfame potassium 20g.
Its preparation process is as follows: take by weighing each component by above-mentioned weight, pulverize, mixing is made adhesive with 80% ethanolic solution, makes softwood, and softwood is waved the granulator granulation through the YK-160 type of 12 mesh sieve eyes, gets wet granular.After treating alcohol volatilization fully, material is placed the multi-functional granulator of DPL-30 type,, finished product moisture is controlled in 5% about one hour of 50 ℃ of fluidized dryings.Sieve, whole grain gets granule.
Embodiment 6
The synthetic sports nutrient replenisher of short muscle of the present invention comprises following component: zinc sulfate 442g (zinc 100g), magnesia 833g (magnesium 500g), creatine ethyl ester 8.48kg (creatine 7000g), vitamin B1 20g, vitamin B2 15g, nicotinic acid 20g, leucine 2k, isoleucine 1kg, valine 1.5kg, white granulated sugar 10kg, citric acid 160g.
Its preparation process is with embodiment 1.
Embodiment 7
Basic preparation process is with embodiment 1, and different is that the key component of sports nutrient replenisher is:
Zinc gluconate 547g (zinc 70g), zinc chloride 354g (zinc 80g), magnesia 500g (magnesium 300g), one hydration creatine 3.85kg (creatine 3000g), two creatine citrate 4.7kg (creatine 4000g), leucine 1kg, isoleucine 0.5kg, valine 0.75kg, white granulated sugar 15kg, citric acid 200g.
The experiment of experimental example 1 product stability
According to " health food evaluation technical regulation ", the synthetic replenishers of the short muscle of embodiment 1～7 gained are placed 37～40 ℃, humidity is under 75% the condition, indexs such as the total plate count of selection energy representative products inherent quality, yeast, mould, every month sampling determination once, continuous three months, it was stable to record index, is equivalent to store 2 years.
The sports nutrient replenisher that the short muscle of experimental example 2 the present invention synthesizes is to the effect of movement human
1 experimental subjects and method
1.1 experimental subjects
20 (19.6 ± 2.3 years old ages of basketball sportsman; Height 194.1 ± 6.2cm; Body weight 86.5 ± 6.3Kg; The training time limit 3.2 ± 1.1 years).
1.2 experimental technique
Grouping: 20 sportsmen are divided into two groups at random, control group (N=10) and experimental group (N=10).Control group is taken placebo, the granule of selecting for use dextrin and white granulated sugar to make; Experimental group is taken the granule that the embodiment of the invention 5 obtains.The experimental session 10g that takes medicine for each person every day, take half an hour before the training, took for 4 weeks continuously.
Test: take medicine preceding, respectively once test after taking medicine, get ulnar vein blood early morning on an empty stomach, carry out serum testosterone and detect; Muscle percentage and muscle mass detect.
Training is arranged: whole experimental session, the sportsman carries out exacting practice by coach's plan.All sportsmen of experimental session do not take other any nutriment.
1.3 key instrument and reagent
Serum testosterone detects and adopts radioimmunology, DFM-96 type-counter; Reagent: Tianjin nine ancient cooking vessel reagent companies; The body composition detection adopts DX200 super strong type body composition test instrument.
1.4 data statistics
The gained data are handled with Excel, adopt double-blind study and t check that test data is carried out statistical analysis, represent with mean ± SD.
2 experimental results and analysis
2.1 testosterone testing result before and after the experiment
Table 1 athletes'serum testosterone test result (T, ng/dl)
A represents to take on the same group the back and takes preceding comparison, and * represents experimental group and control group relatively.
As can be seen from the above table, the athletic serum testosterone of control group descends between hard training phase to some extent, and has utmost point significant difference, and experimental group level of serum testosterone and the preceding no significant difference of experiment.After the check experiment, there are the difference of utmost point conspicuousness in test group and control group testosterone levels.
2.2 muscle percentage testing result before and after the experiment
Table 2 sportsman muscle percentage testing result (%)
A represents to take on the same group the back and takes preceding comparison, and * represents experimental group and control group relatively.
As can be seen from the above table, the athletic muscle percentage of control group rises between hard training phase to some extent, but there was no significant difference.And experimental group muscle percentage obviously increases, through check with take before reach control group and compare the rising that conspicuousness is all arranged.
2.3 muscle weight testing result before and after the experiment
Table 3 sportsman muscle weight testing result (kg)
A represents to take on the same group the back and takes preceding comparison, and * represents experimental group and control group relatively.
As can be seen from the above table, the athletic muscle weight of control group rises between hard training phase to some extent, but there was no significant difference.The experimental group muscle weight raises and has significant difference.
3 conclusions
The sports nutrient replenisher that the short muscle that the present invention obtains is synthetic help keeping level of serum testosterone during the large amount of exercise, and it is synthetic to help short muscle.
Claims (10)
1, the synthetic sports nutrient replenisher of a kind of short muscle is characterized in that, its main component and by weight proportioning be:
20～400 parts of the compounds of zinc (by zinc ion weight)
40～1000 parts of the compounds of magnesium (by magnesium ion weight)
2000～10000 parts of creatine compounds (by creatine weight).
2, the synthetic sports nutrient replenisher of short muscle according to claim 1 is characterized in that, its main component and by weight proportioning be:
40～300 parts of the compounds of zinc (by zinc ion weight)
80～600 parts of the compounds of magnesium (by magnesium ion weight)
4000～8000 parts of creatine compounds (by creatine weight).
3, the synthetic sports nutrient replenisher of short muscle according to claim 1 and 2 is characterized in that, its main component and by weight proportioning be:
50 parts of the compounds of zinc (by zinc ion weight)
100 parts of the compounds of magnesium (by magnesium ion weight)
6000 parts of creatine compounds (by creatine weight).
4, according to each described sports nutrient replenisher of claim 1～3, it is characterized in that the compound of described zinc is selected from one or more in zinc acetate, zinc carbonate, zinc chloride, zinc citrate, zinc gluconate, zinc lactate, zinc sulfate, the zinc oxide.
5, according to each described sports nutrient replenisher of claim 1～4, it is characterized in that the compound of described magnesium is selected from one or more in magnesium carbonate, magnesium chloride, magnesium citrate, magnesium gluconate, magnesium glycerophosphate, magnesium lactate, magnesia, phosphoric acid magnesium salts, magnesium sulfate, the Magnesium Asparticum.
According to each described sports nutrient replenisher of claim 1～5, it is characterized in that 6, described creatine compound is selected from one or more in a hydration creatine and creatine hydrochloride, creatine malate, creatine citrate, the creatine ethyl ester.
According to each described sports nutrient replenisher of claim 1～6, it is characterized in that 7, described creatine compound is quick-releasing type product or spacetabs type product.
8, according to each described sports nutrient replenisher of claim 1～7, it is characterized in that, also comprise mineral matter, vitamin or amino acid.
According to each described sports nutrient replenisher of claim 1～8, it is characterized in that 9, the formulation of described sports nutrient replenisher is pulvis, capsule, granule or tablet.
According to the described sports nutrient replenisher of claim 9, it is characterized in that 10, described sports nutrient replenisher also comprises auxiliary material, it is selected from starch, dolomol, cellulose, silica, talcum powder, lactose, the dextrin one or more.
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| CN2008101167567A CN101331949B (en) | 2008-07-16 | 2008-07-16 | Sports nutrient replenisher for promoting muscle synthesize |
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| CN2008101167567A CN101331949B (en) | 2008-07-16 | 2008-07-16 | Sports nutrient replenisher for promoting muscle synthesize |
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| CN101331949B CN101331949B (en) | 2012-11-21 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101885780A (en) * | 2010-06-21 | 2010-11-17 | 华南理工大学 | Preparation method of starch based zinc-supplementing |
| CN106805227A (en) * | 2016-12-28 | 2017-06-09 | 安徽省虹升生物股份有限公司 | The method of the nutrition fortifier prepared based on creatine monohydrate |
| CN106880054A (en) * | 2017-03-06 | 2017-06-23 | 青岛海大华旗生物科技有限公司 | A kind of health food for preventing and treating muscular dystrophy and preparation method thereof |
| CN109527585A (en) * | 2018-12-26 | 2019-03-29 | 浙江华康药业股份有限公司 | A kind of alimentation composition and preparation method thereof that can prevent gentle expelling pathogenic factors from muscles and skin and lack disease |
| EP3355989A4 (en) * | 2015-10-02 | 2019-06-05 | Balchem Corporation | Composition for improved performance |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006034586A1 (en) * | 2004-09-29 | 2006-04-06 | Aplodan Formulations Ltd. | Nutritional composition for promoting muscle performance and acting as hydrogen (h+) blocker |
| US7645742B2 (en) * | 2005-06-22 | 2010-01-12 | Advocare International, L.P. | Composition for enhancing cellular energy |
| CN100356876C (en) * | 2005-09-30 | 2007-12-26 | 北京康比特威创体育新技术发展有限公司 | Beverage for promoting sportive recovery from fatigue |
| CN101209109B (en) * | 2006-12-31 | 2011-04-27 | 北京康比特体育科技股份有限公司 | Composition with muscle-increasing function and beverage prepared thereby |
-
2008
- 2008-07-16 CN CN2008101167567A patent/CN101331949B/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101885780A (en) * | 2010-06-21 | 2010-11-17 | 华南理工大学 | Preparation method of starch based zinc-supplementing |
| CN101885780B (en) * | 2010-06-21 | 2012-05-09 | 华南理工大学 | Preparation method of starch based zinc-supplementing nutrient reinforcer |
| EP3355989A4 (en) * | 2015-10-02 | 2019-06-05 | Balchem Corporation | Composition for improved performance |
| CN106805227A (en) * | 2016-12-28 | 2017-06-09 | 安徽省虹升生物股份有限公司 | The method of the nutrition fortifier prepared based on creatine monohydrate |
| CN106880054A (en) * | 2017-03-06 | 2017-06-23 | 青岛海大华旗生物科技有限公司 | A kind of health food for preventing and treating muscular dystrophy and preparation method thereof |
| CN109527585A (en) * | 2018-12-26 | 2019-03-29 | 浙江华康药业股份有限公司 | A kind of alimentation composition and preparation method thereof that can prevent gentle expelling pathogenic factors from muscles and skin and lack disease |
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| Publication number | Publication date |
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| CN101331949B (en) | 2012-11-21 |
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