CN101278834A - Electro cardiscope wireless remote monitoring system based on GPRS - Google Patents

Abstract

The invention provides a cardiac electric wireless remote monitoring system based on GPRS, pertaining to the field of human body physical parameters detection and electronic medical instruments. The invention comprises a cardiac electric electrode, a cardiac electric amplifier, a core processor and a serial port which is connected with the core processor, a liquid crystal display circuit, a GPRS module and so on. The detection end of the cardiac electric electrode is connected with the human body, the output end of the cardiac electric electrode is connected with the core processor by the cardiac electric amplifier and the cardiac electric electrode transmits the collected cardiac electric signal to the core processor. If the cardiac electric signal is abnormal, the core processor sends warning information by the GPRS module and transmits the cardiac electric signal to a receiving terminal of the doctor by the GPRS module. If the cardiac electric signal is abnormal, the invention can automatically transmit warning information by the GPRS module, thus reducing the danger of the patient. At the same time, the system can transmit the electrocardiogram of the disease to the receiving terminal of the doctor by the GPRS for diagnosis and analysis.

Description

Electro cardiscope wireless remote monitoring system based on GPRS

Technical field

The present invention is a kind of electro cardiscope wireless remote monitoring system based on GPRS, belongs to human body physiological parameter and detects and electronic medical instrument field.

Background technology

Along with the development of sensor technology, wireless communication technology and information technology, tele-medicine and home health care have obtained more wide development space.In the home health care the most normal use be cardiac monitoring.Old people's healthy problem has caused society's concern more and more widely at present.Simultaneously there is nearly 60% heart class disease death to occur in family and the community's scope according to Chinese medicine association statistics.If therefore can find anomalous ecg in early days and in time notify family members, just can improve its chances of survival for the patient strives for valuable therapeutic time.Medical practice shows that if can in time find and do appropriate processing for heart class disease, the patient then has 70%～80% survival rate.The portable design of electrocardiogram monitor has become the inexorable trend that the modern medicine instrument develops thus.Present most of electrocardiogram monitor costs are higher, and complicated operation, and adopt wired communication modes has limited patient's the scope of application, do not reach dynamic guard purpose.

Summary of the invention

The object of the present invention is to provide a kind of electro cardiscope wireless remote monitoring system based on GPRS.Native system can reach the patient is carried out real-time cardiac bioelectricity monitoring, can carry out automatic analyzing and diagnosing to patient's electrocardio simultaneously, and can show the triple channel ecg wave form in real time on liquid crystal display screen.If the generation anomalous ecg, system also can send warning message by GPRS automatically.

To achieve these goals, the present invention has taked following technical scheme.Native system includes electrocardioelectrode, ecg amplifier, core processor, serial ports, USB mouth, JTAG mouth, network interface, memory module, liquid crystal display circuit, touch screen circuitry and electric power management circuit; The end of probe of electrocardioelectrode links to each other with human body, and the outfan of electrocardioelectrode links to each other with core processor by ecg amplifier, and electrocardioelectrode is gathered electrocardiosignal from human body, and the signal that collects is amplified, sends among the S3C2410A after the filtering and handle.Native system also includes the GPRS module that links to each other with core processor, if electrocardiosignal is unusual, core processor sends warning message by the GPRS module, also electrocardiosignal is transferred to the receiving terminal at doctor place simultaneously by the GPRS module.

Native system also includes the warning circuit that comes off that leads, and the described warning circuit that comes off of leading can be reported to the police by bright lamp when electrocardioelectrode and human body break away from, and prompting comes off.

That described core processor is selected for use is 32 bit processor S3C2410A.

This instrument adopts 32 single-chip microcomputers of low-power consumption as core processor, and select for use Linux as operating system, can reach the patient is carried out real-time cardiac bioelectricity monitoring, can carry out automatic analyzing and diagnosing to patient's electrocardio simultaneously, and can on liquid crystal display screen, show the triple channel ecg wave form in real time.If the generation anomalous ecg, system also can be automatically sends warning message by GPRS, reduces the sick danger of sending out of patient, and the electrocardiogram in the time of simultaneously can be with morbidity is transferred to the receiving terminal at doctor place by GPRS, for the diagnosis analysis.

Description of drawings

Fig. 1: system construction drawing

Fig. 2: the software flow pattern of system's transmitting terminal

Fig. 3: the software flow pattern of system receiving terminal

Fig. 4: electrocardiosignal amplification filtering circuit diagram 1

Fig. 5: electrocardiosignal amplification filtering circuit diagram 2

Fig. 6: system power supply part schematic diagram

Fig. 7: system LCD part schematic diagram

Fig. 8: other interface principle figure of system

Fig. 9: overall system connection layout

The specific embodiment

The present invention is based on the electrocardio wireless remote monitoring of GPRS, and system block diagram as shown in Figure 1.System includes electrocardioelectrode, ecg amplifier, core processor, serial ports, USB mouth, JTAG mouth, network interface, liquid crystal display circuit, touch screen circuitry, GPRS module and electric power management circuit.Electrocardioelectrode links to each other with ecg amplifier with human body respectively, and electrocardioelectrode is used for gathering analogue signal, and sends the signal that collects to ecg amplifier, and ecg amplifier amplifies, sends in the core processor after the filtering and handle this signal.System can carry out transfer of data by USB mouth, serial ports, also can pass through JTAG mouth programming start-up code, and simultaneity factor can link to each other with Internet by network interface.Electrocardioelectrode can directly be gathered three-channel electrocardiosignal from body surface, and can be to the electrocardioelectrode detection of leading, and comes off if detect the loosening lamp that then can light different colours corresponding leading of reporting to the police.System adopts 32 single-chip microcomputers as core controller, signal can be presented on the liquid crystal display screen, and liquid crystal display screen has touch screen functionality, and system also can send to receiving terminal with electrocardiosignal by the GPRS module.System uses battery powered, by power conversion chip input voltage is converted to the needed running voltage of system.

Present embodiment adopts S3C2410A as core processor, and S3C2410A has adopted the ARM920T kernel, the CMOS standard macroelement and the memory cell of 0.18um technology, and its speed of service reaches as high as 266MHz.S3C2410A has 8 path 10 position ADC and touch screen interfaces, therefore do not need to add the ADC chip, also have 3 passage UART simultaneously, 2 passage USB master controllers/1 passage USB device controller and 117 general purpose I/O, make Design of Interface Circuit simpler, integrated level is higher, and the volume of instrument significantly reduces, and has strengthened the portability of monitor.

The electrocardio amplification filtering circuit of system such as Fig. 4, shown in Figure 5, it by pre-amplification circuit, main amplifying circuit, low pass filter, level lifting circuit and the warning circuit that comes off of leading form.38 foot IC chip AD620 have been used in the circuit altogether, 7 14 foot IC chip LM342 and 2 14 foot IC chip 74LS08 have that high-gain, high input impedance, high cmrr, low noise, low drift, dynamic range are big, a stable performance, characteristics such as safe in utilization.From the electrocardiosignal of body surface collection is very faint, and the peak value of general electrocardiosignal is approximately 1mV, and the frequency of body surface ecg mainly concentrates on 0.05-100Hz, and mid frequency is 17Hz, is a kind of low-frequency faint bipolar signal.It is submerged in the many stronger interference and noise, mainly is from the interferential influence of 50Hz power frequency.Therefore, accurately measure, must design the amplification filtering circuit of function admirable, and amplification is at least 1000 times electrocardiosignal.In actual applications, the gain of one-level amplifying circuit does not surpass 100 times usually, and high again amplification will cause the vibration of circuit, amplifies so we are divided into two-stage with amplifying circuit.We adopt AD620 to amplify as the first order.AD620 is a kind of low-power consumption, high-precision meter amplifier, its available non-essential resistance is regulated 1-1000 amplification doubly, although AD620 is formed by three traditional amplifier amplifier law of development, some main performances are better than the instrument amplifier that is made of three amplifiers.Amplification computing formula according to AD620 ${\mathrm{<figure-callout\; id="1"\; label="A"\; filenames="A20081011312900151.png,A20081011312900171.png"\; state="\{\{state\}\}">A</figure-callout>}}_1=\frac{49.4\mathrm{K\&Omega;}}{R}+1$ Can calculate the amplification of the first order.Wherein R is the resistance between AD620 pin 1 and 8, here is the resistance sum of R103 and R104, and we select R103=750 Ω for use here, R104=750 Ω.Calculate according to formula, first order amplification is about 34 times.At first order input input 20Hz, peak-to-peak value is the sinusoidal signal of 20mV, can detect 20Hz at first order outfan with signal generator for we, and peak-to-peak value is the sinusoidal signal of 0.72V, has amplified 35.5 times approximately, meets substantially and estimates amplification.Second level amplifying circuit adopts LM324 to realize.We are at the input input 20Hz of second level amplifying circuit, and peak-to-peak value is the sinusoidal signal of 20mV, and outfan records 20Hz in the second level, and peak-to-peak value is the sinusoidal signal of 892mV, has amplified 45 times approximately.So far, whole amplifying circuit amplifies about 1530 times altogether.Because the mid frequency of electrocardiosignal is 17Hz, so we only need collection 40Hz just can describe the feature of electrocardiosignal and judge its abnormal conditions with interior signal.And the low-pass filtering by 40Hz, can filter out also that the 50Hz power frequency is disturbed and the influence of high-frequency signal.Because the inside A/D module of S3C2410A single-chip microcomputer can only be changed the signal of 0-3.3V, so need carry out level conversion to electrocardiosignal, makes its waveform be in positive interval, therefore, need the design level lifting circuit to improve the voltage of electrocardiosignal.Portable ecg monitor is the instrument that the patient carries, and the line that leads is easy to come off, and this will introduce very big interference, cause the ecg wave form distortion, make electrocardiogram monitor be difficult to export actual waveform, thereby cause false judgment, influence diagnostic result electrocardiosignal.Therefore we have designed the circuit that comes off that leads, and use 1 14 foot IC chip 74LS08 and 3 14 foot IC chip LM324 in the circuit, to reach the alarm effect of leading when coming off.The electrocardiosignal of amplifying by ecg amplifier is admitted to the circuit that comes off of leading simultaneously and detects, and judges voltage whether within the scope of coming off of leading, and comes off if exceed normal range and then report to the police to lead.We select tri-colour LED (red, yellow, green) prompting to lead to come off, and each leads all has the display lamp of a color coupled, and when this leads when coming off, then corresponding display lamp can light prompting and come off.

The communication mode of present embodiment adopts the GPRS wireless module, and therefore the GPRS network broad covered area has greatly enlarged the range of activity of user, makes its quality of life be improved.That the GPRS module of system adopts is the GSM/GPRS double frequency module SIM100-E that SIMCOM company produces.SIM100-E is mainly voice transfer, short message and data service wave point is provided.SIM100-E is integrated complete radio circuit and the baseband processor of GSM are suitable for developing the wireless application product of some GSM/GPRS, and as mobile phone, handheld device, wireless POS machine and wireless data transmission business, range of application is very extensive.The SIM100-E module provides the system interface of complete function for the user.The 60Pin system connector is the connecting interface of SIM100-E module and application system, and external power source, RS-232 serial ports, SIM interface and audio interface mainly are provided.The built-in AT command set of SIM100-E, ICP/IP protocol.Under the control of single-chip microcomputer, utilize existing GPRS network to carry out Signal Processing and transmission, thereby realize the purpose of long distance wireless monitoring.The SIM100-E module can realize data and wireless communication functions such as voice transfer, short message and fax services in fast and reliable ground.System can carry out the data transmission of electrocardiosignal by GPRS, and the software flow of system's transmitting terminal as shown in Figure 2.After bringing into operation, system carries out collection, the demonstration of electrocardiogram (ECG) data, and the electrocardiosignal that collects handled, judge whether it is unusual, once find to have abnormal electrocardiogram, then touch the GPRS module and send warning message to fixing mobile phone, and abnormal electrocardiographic pattern is sent to receiving terminal.The software flow of system receiving terminal as shown in Figure 3.System receiving terminal is a PC with public network IP that is connected to Internet.This PC operation receiving terminal software is constantly monitored the connection request from designated port then, receives into as data and then deposits relief area in, and the byte array is changed into the int data, separates out the triple channel data and demonstrate ecg wave form on screen.

Electrocardiogram (ECG) data is gathered from body surface by system, amplify, send into S3C2410A after the Filtering Processing and handle via analog amplify circuit, AD module by single-chip microcomputer inside is carried out the A/D conversion to analogue signal, and the ecg wave form that collects reached on the LCD shows.System also can pass through serial ports, the USB mouth links to each other with PC, also can link to each other with the Internet network by network interface.Because system is the portable cardiac monitoring, therefore need to use battery powered, system to adopt 3 joint dry cell power supplies, be about 4.5V.The core operational voltage of S3C2410A is 1.8V, and the running voltage of memorizer and exterior I/O is 3.3V, liquid crystal display screen needs+5V ,+15V ,-10V to be providing the bias voltage of normal demonstration, and drive LED backlight+back facet current about 25V voltage backlight and 15mA.Single power supply conversion is difficult to reach these requirements, therefore needs a plurality of chips to realize these voltage.Power circuit as shown in Figure 6.System mainly adopts three kinds of power supply chip LTC3441, LTC1911-1.8 and MAX1578ETG.LTC3441 is a conversion efficiency up to 95%, the buck-boost type DC/DC transducer of fixed frequency, and it can be higher than, be less than or equal under the condition of output voltage at input voltage carries out efficient operation.The design topology that this chip adopted can provide a conversion continuously by all operations pattern, under the burst mode operation state, quiescent current only is 25 μ A, meet the low power dissipation design of native system, thereby make it become the ideal selection that output voltage is in interior single-unit lithium ion battery applications of battery voltage range or multiple batteries application.Burst mode operation is controlled by the user, and can enable by driving MODE/SYNC pin to high level.If the MODE/SYNC pin is driven to low level or has a clock, then the fixed frequency switching manipulation is enabled.LTC1911-1.8 be input voltage from 2.7V to 5.5V, output voltage is 1.8V, output current can reach buck charge pump DC/DC changer of 250mA.Its main feature is the conversion efficiency height, than general linear voltage regulator efficient high by 25% (representative value); Fixedly the 1.5MHz oscillator frequency not only provides low noise voltage stabilizing output, and its input noise is also low than the charge pump that general voltage stabilizing is exported, and has reduced the capacity of output filter capacitor; Power consumption is little, quiescent current 180 μ A, 10 μ A during closed condition; Soft start function is arranged; Short circuit and overtemperature protection are arranged; Only need external 4 electric capacity (2 1 μ F electric capacity and 2 10 μ F electric capacity) can constitute operating circuit.PWREN on the CPU is an enable signal, and in the time of the Power off of system, PWREN can become low level, and then VDD1.8 stops power supply, but does not influence VDD1.8alive, VDD1.8alive normal power supply.VDD1.8alive is that institute helps waking up once more of system so that one directly maintains electricity condition for the RTC of CPU and RESET power supply.MAX1578ETG provides 4 the tunnel to regulate output, can satisfy all voltage requirements of the small-sized active matric TFT-LCD display that handheld device uses, and try one's best in these equipment few outer member and high efficiency are necessary.Each device all comprises three advanced charge pump and boost converters of being used for the LCD bias supply, and this transducer can drive nearly 8 and be used for series connection White LED backlight, and input voltage range is 2.7V to 5.5V.Charge pump for the LCD biasing circuit provide fixed+5V ,+15V and-10V voltage, need not external diode.After efficient, fractional-type (1.5 times/2 times) charge pump followed by a low pressure difference linear voltage regulator, for Source drive provides+5V voltage.Automatic mode switches has realized the highest conversion efficiency.Two multistage, high voltage charge pump generation+15V and-10V voltage, be used to provide V _ONAnd V _OFFUtilize clock scheme and inner drive, these charge pumps have been eliminated parasitic charging current impulse disturbances and have been reduced maximum input current, thereby have guaranteed very low electromagnetic radiation.Realization is exported in proper order when startup and shutoff.High efficiency inductance type boost converter reaches 8 with constant current driven and is used for series connection White LED backlight.Thereby placed in-line connected mode makes the identical brightness of illumination of having unified of each LED electric current, also makes the line of LED minimum.MAX1578ETG regulates constant LED electric current in whole temperature range.MAX1578ETG adopts and saves the slim QFN encapsulation of spatial 24 pin 4mmx4mm.Its efficient is also comparatively desirable, and charge pump is 83%, and boost converter is 84%.Therefore, MAX1578ETG is fit to be applied in the native system very much.

The digital circuit of system is partly integrated LCD display module, serial communication modular, USB module, JTAG module, memory module and network interface card module can be finished functions such as ecg signal acquiring, demonstration, analysis, warning.

LCD display is a most important outut device in the system.Lcd controller among the S3C2410A can be supported STN and two kinds of LCD of TFT.That system adopts is 3.5 inches transflective TFT-LCD:LQ035Q7DH02 of Sharp company, and the LCD circuit as shown in Figure 7.Because LQ035Q7DH02 does not comprise controller, need to cooperate control circuit to use.The function of the lcd controller in the S3C2410A chip is that the display buffer of LCD view data from system hosts moved in the external LCD drive device, it can be supported up to 4K color STN display and 256K color TFT display, support the various liquid crystal display screens under the highest 1024 * 768 resolution, have the DMA of LCD special use.The lcd controller of S3C2410A chip internal is used for controlling image data transmission, and its interface signal mainly contains 24 data lines and 9 control signal wires.Because lcd controller and the display LQ35Q7DH02 of S3C2410A can't mate on data format and display timing generator, so need select for use a kind of sequencing contro IC to come different data and sequential are shone upon.The sequencing contro IC of system selects the LZ9FC22 of Sharp company for use.The LCD that this chip is exclusively used in TFT type QVGA screen (screen resolution is 320 * 240) carries out sequencing contro.This is the controller of a 18bit (R6G6B6), is RGB565 16bit mode of operation because system adopts, so in fact these two pins of R0 and B0 do not import useful signal.In order to give full play to the data-handling capacity of S3C2410A, system adopts the SDRAM parallel connection of two 16 bit data width to be built into the SDRAM accumulator system of 32 bit data width, has improved the communication efficiency of itself and CPU.

System has realized the serial communication with PC by the RS-232 serial ports.Because the defined high-low level signal of standard of RS-232 is different fully with the defined high-low level signal of the LVTTL circuit of S3C2410A, thus the two communicate must be by the conversion of signal level, adopt MAX3232 to realize here.USB is a kind of emerging computer external serial communication interface standard, it overcomes the defective of serial/parallel mouthful of traditional computer, has hot plug, plug and play, transfer of data is reliable, and expansion is convenient, advantages such as low cost, become one of interface of current computer indispensability, also be widely used in the design of embedded system simultaneously.USB adopts four cables, and wherein two is the serial-port that is used for transmitting data, and in addition two provide power supply for upstream device.It supports two kinds of data transmission rates, and at a high speed and need the peripheral hardware of high bandwidth, USB is 12Mbps transmission data at full speed; Then transmit for the low speed peripheral hardware with the transfer rate of 1.5Mbps.Usb bus can automatically switch between two kinds of patterns according to the peripheral hardware situation.

Ethernet interface is to be used for the interface that links to each other with Internet, and our electrocardiogram monitor system need be realized the function of embedded web server, makes the outside and to check ecg wave form by Internet access means terminal.Here we adopt AX88796 to realize its function as network interface card, and the standard of employing RJ45 interface is connected with network.Ax88796 is the compatible fast Ethernet controller of NE2000 that Taiwan Asix company releases.The SRAM that its internal integration has the adaptive physical layer transceiver of 10/100Mb/s and 8K * 16 supports multiple cpu bus patterns such as MCS-51 series, 80186 series and MC68K series.Ax88796 carries out the 10Mb/s and the 100Mb/s Ethernet control function of basic what IEEE802.3/IEEE802.3u local-area network standard, and IEEE802.3u is provided compatible media independent interface MII (Media IndependentInterface), in order to support the application on other medium.In addition, Ax88796 also provides available standard print interface, can be used for connecting PRN device or be used as general I/O connecting.The circuit of each interface section of system as shown in Figure 8.Final system need get up each module combinations, and as much as possible little dimensionally.Because S3C2410A is encapsulated as the BGA272 spherical package, many signals are difficult to therefrom draw, and consider simultaneously to have many high speed signals in the circuit board, crosstalk between the signal and electromagnetic interference in order to get rid of, and make system works stable, and we adopt the design of six laminates.The whole connection layout of system as shown in Figure 9.

Utilize this monitor system, we carry out the following steps test.At first open hyper terminal, will show CMD after system powers on and occur on hyper terminal, then system has begun to start.When seeing in the LCDs upper left corner when having the penguin icon to occur, then illustrative system starts and finishes.If at hyper terminal operation ./button, system then begins to carry out electrocardio and detects, system will carry out the electrocardio detection, analyze afterwards, and what show on the screen is that detected I leads, II leads, III leads three-channel electrocardiosignal and heart rate.When system has detected abnormal electrocardiogram, then touch the GPRS module and send warning message to mobile phone, and the abnormal electrocardiogram data are sent to receiving terminal.System can detect multiple abnormal electrocardiogram signal (tachycardia, bradycardia, arrhythmia, stop fighting, leak and fight).

For the further effectiveness and the accuracy of verification system, we compare the actual parameter of the ecg wave form that testing result and electrocardiosignal generator are produced, and its result is as shown in table 1.Visible detection result's hrv parameter is consistent with the electrocardiosignal parameter that reality produces basically, and this has reflected the accuracy of system.Accuracy simultaneously in order to verify that GPRS receiving terminal data receive, we do with relatively the electrocardiosignal of transmitting terminal and receiving terminal, and the heart rate of transmitting terminal transmission is the electrocardiogram (ECG) data of average 140 times/minute three passages, and the time is 5s, is about 10 cardiac electrical cycle.Receiving terminal can correctly receive, and can do to analyze electrocardiosignal, receiving terminal is shown as and receives 10 cardiac electrical cycle, and we select one of them passage to carry out the analysis of electrocardiogram (ECG) data, what select here is the electrocardiosignal of the 3rd passage, and analyzing and drawing its average heart rate is 139 times/minute.

Test result shows: this electrocardio monitor is simple to operate, and working stability can and carry out real-time monitoring and warning to electrocardiosignal.

Table 1 testing result relatively

Sequence number	1	2	3	4	5	6	7	8	9	10
											Actual heart rate (inferior/minute)	30	40	45	60	80	90	100	110	120	140
The measurement heart rate (inferior/minute)	30	42	47	60	80	90	101	110	121	141

Claims (3)

1,, includes electrocardioelectrode, ecg amplifier, core processor, serial ports, USB mouth, JTAG mouth, network interface, memory module, liquid crystal display circuit, touch screen circuitry and electric power management circuit based on the electro cardiscope wireless remote monitoring system of GPRS; The end of probe of electrocardioelectrode links to each other with human body, and the outfan of electrocardioelectrode links to each other with core processor by ecg amplifier, and electrocardioelectrode sends the electrocardiosignal that collects to core processor; It is characterized in that: also include the GPRS module that links to each other with core processor, if electrocardiosignal is unusual, core processor sends warning message by the GPRS module, also electrocardiosignal is transferred to the receiving terminal at doctor place simultaneously by the GPRS module.

2, the electro cardiscope wireless remote monitoring system based on GPRS according to claim 1 is characterized in that: also include the warning circuit that comes off that leads.

3, according to claim 1 or the described electro cardiscope wireless remote monitoring system based on GPRS of claim 2, it is characterized in that: that described core processor is selected for use is 32 bit processor S3C2410A.

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