CN101259252A - Chinese medicinal composition for treating ovarian cyst and preparation thereof - Google Patents

Abstract

The present invention relates to a traditional Chinese medicine combination for remedying the ovarian cyst. The traditional Chinese medicine combination is made from milkvetch root, salvia, angelica, Szechwan lovage rhizome, coix seed, laminaria japonica, seaweed, achyranthes root, common yam rhizome, pseudo ginseng root, red peony root, nutgrass galingale rhizome, curcuma longa, tangerine seed and/or a pharmic acceptable carrier. The present invention also relates to a preparation method of the traditional Chinese medicine combination. The traditional Chinese medicine combination of the present invention has the effects of warming spleen and stomach for dispelling cold, strengthening the spleen for removing damp, removing toxic substances for dispersing stagnation, nourishing liver and kidney, etc. and is used for the such symptoms as underbelly or iliac fossa turgor, tenesmus, bellyache, paramenia caused by the ovarian cyst.

Description

A kind of Chinese medicine composition for the treatment of ovarian cyst and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, specifically, relate to a kind of Chinese medicine composition for the treatment of ovarian cyst and preparation method thereof.

Background technology

Ovarian cyst is meant has the swollen thing of capsule to form in the ovary, can be divided into tumprigenicity and non-tumprigenicity two classes.The ovarian cyst that common people say is meant nontumorous that class.

Tumprigenicity ovarian cyst: say that exactly it belongs to ovarian tumor, since it is optimum and pernicious to be that tumor just has, the branch of capsule, reality, the case fatality rate of malignant tumor of ovary is higher, occupies the first place of gynecological tumor, therefore in case determine it is ovarian tumor, even the cystic tumor of ovary is as serous cystadenoma, mucinous cystadenoma, benign cystic teratoma etc., though mostly be optimum greatly, but be converted into virulent possibility, therefore all need the early operation excision.

Non-tumprigenicity ovarian cyst: claim non-superfluous natural disposition ovarian cyst again, be the functional cyst of ovary mostly, comprise follicular cyst, corpus lutein cyst, leuteivic cyst, struvite ovarian cyst, polycystic ovary and endometrial implantatior cyst (being chocolate cyst of ovary).Ovarian cyst belongs to non-tumprigenicity cyst mostly, and diameter also seldom surpasses 5 centimetres, and these cysts are not tumor, and major part is benign, can disappear voluntarily, need not operation.

Ovarian tumor is one of common gynecological disease, ranks first in the tumor of each organ of whole body more than its kind, and its prevalence in gynaecopathia is 13-23.9%, and wherein malignant tumor accounts for 10%.Ovarian tumor can occur in any age, occurs in the childbearing age at majority, and benign ovarian tumor occurs in 20-44 year mostly, malignant ovarian tumor occurs in 40-50 year, adolescence or youngest daughter also can suffer from ovarian tumor, often are pernicious, and postmenopause trouble tumor also mostly is pernicious.Because the ovum tumor is positioned at pelvic cavity, asymptomatic in early days, and the malignant tumor diffusion is fast, has been late period when the patient seeks medical advice more than 70%, only about 30%, its mortality rate occupies position first of the gynecologic malignant tumor according to report ovarian cancer five-year survival rate both at home and abroad.

The cardinal symptom of ovarian cyst has:

1, lower abdomen sense of discomfort: for the patient does not touch down initial symptom before the abdominal lump.Because the weight of tumor itself and be subjected to enterokinesia and the influence of position change, make that tumor is mobile in pelvic cavity to involve its base of a fruit and infundibulopelvic ligament, so that the patient there are lower abdomen or the inflation of bone nest portion, bearing down.

2, abdominal circumference increase slightly, swollen thing in the abdomen: be the most normal phenomenon that has.Clothes or belt that the patient perceives oneself seem tightly little, notice that just now abdominal part increases, or in the accidental sensation of daystart, thereby oneself find to have in the abdomen swollen thing, abdominal distention discomfort in addition by abdominal part.

3, stomachache: do not have complication as tumor, few pain.Therefore, oophoroma patient feel stomachache, send out the survivor especially suddenly, the polyphyly tumor pedicle twists, occasionally for tumor break, hemorrhage or the infection due to.In addition, pernicious cyst causes stomachache, skelalgia more, and pain often makes the patient go to a doctor with emergency case.

4, menoxenia: general ovary, even bilateral ovaries cyst, owing to do not destroy all normal ovarian tissues, so do not cause menoxenia mostly.The metrorrhagia that has does not belong to incretion, or changes because of oophoroma makes the vascularity of pelvic cavity, causes that endometrium is congested and rises; Or owing to malignant tumor of ovary directly is transferred to due to the endometrium.The menoxenia that is taken place because of the incretion tumor often merges other secretion influences.

5, pressure symptom: huge ovarian tumor can cause dyspnea and cardiopalmus because of the compressing diaphragm, and ovarian tumor merges a large amount of ascites persons also can cause this kind symptom; But the dyspnea of the patients with ovarian tumor that has system is by due to a side or the bilateral pleural effusion; And often merge ascites, form so-called M eigs syndrome.

Ovarian cyst can be prevented, regularly do gynecologial examination, menstrual phase and postpartum women should be specifically noted that and conserve one's health, forbid sexual life, keep the cleaning of pudendum and vagina, and mood is freely stable, alleviate the various competitive pressure in the life as far as possible, must guard against and be worried tired angryly, association's self regulation, noting warmingly, avoiding catching cold, paddle in spite of the rain, or cold water drip washing, swimming etc., appropriate level of work and rest, diet is nutritious, suitable light, easy digestion, the irritable food of avoiding eating anything raw or cold keeps body healthy energy abundance, QI and blood is unobstructed, physical and mental health.The traditional Chinese medical science thinks that ovarian cyst belongs to categories such as " addiction abdominal mass ", " stony mass of uterus ", " mass in the abdomen ".According to women's physiology and pathological characters, the formation of ovarian cyst many because of menstrual period, puerperal six climate exopathogens (wind, cold, summer-heat, wet, dry, fire) heresy invasion, seven emotions (are liked, anger, melancholy is thought compassion, probably, frightened) damage, sexual life reaches improper diet and overtiredness accidentally, so that deficiency of vital QI, disorder of QI and blood, then internal organs are become estranged for a long time, and QI and blood is well-behaved to be disobeyed, the mechanism of qi retardance, blood stasis is detained, the turbid cohesion of expectorant, long-pending for a long time forming.

The traditional Chinese medical science is divided into three types with this disease:

(1) qi stagnation and blood stasis type: showing as few abdomen one side or bilateral has lump, the many non-evident symptons of the little person of lump, and big person's cardiopalmus asthma, the soreness of waist, under the lower abdomen, it is not smooth to defecate, urine urgency-frequency, tongue has petechia.

(2) cold-damp stasis type: abdominal part has lump.Edema of lower limbs, the abdomen hydrothorax, lack of appetiteization stagnates.

(3) gas stasis of blood heat-transformation type: scurry pain in the abdomen acutely, the abdominal distention nausea, fever with chills, spirit is gloomy, unable asthenia, leukorrhagia increases, and the thick raw meat of matter is dirty.Various to have common characteristic to be that ovarian cyst is mainly in one-sided, and peplos is complete, activity, smooth surface, no ascites is capsule, cyst wall is smooth, form one to, make slow progress, the course of disease is more.

The traditional Chinese medical science adopts that warming spleen and stomach for dispelling cold, spleen invigorating are dried, this disease of decoction for the treatment of detoxicating and resolving stagnation of pathogens, nourishing the liver and kidney.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of ovarian cyst.

The present invention also aims to provide a kind of preparation method of this Chinese medicine composition.

In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of ovarian cyst, be to make by effective ingredient and/or pharmaceutically acceptable carrier, described effective ingredient is made by weight by following raw materials according:

Radix Astragali 10-20 part Radix Salviae Miltiorrhizae 5-10 part Radix Angelicae Sinensis 20-30 part

Rhizoma Chuanxiong 15-20 part Semen Coicis 10-15 part Thallus Laminariae (Thallus Eckloniae) 20-30 part

Sargassum 10-20 part Radix Achyranthis Bidentatae 15-20 part Rhizoma Dioscoreae 5-10 part

Radix Notoginseng 15-25 part Radix Paeoniae Rubra 10-20 part Rhizoma Cyperi 15-20 part

Radix Curcumae 10-20 part Semen Citri Reticulatae 20-25 part

Effective ingredient is preferably made by weight by following raw materials according:

26 parts of 8 parts of Radix Angelicae Sinensis of 16 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali

26 parts of 13 parts of Thallus Laminariae (Thallus Eckloniae)s of 18 parts of Semen Coiciss of Rhizoma Chuanxiong

8 parts of 18 portions of Rhizoma Dioscoreaes of 16 parts of Radix Achyranthis Bidentataes of Sargassum

18 parts of 16 portions of Rhizoma Cyperis of 20 parts of Radix Paeoniae Rubra of Radix Notoginseng

23 parts of 16 parts of Semen Citri Reticulataes of Radix Curcumae

The present invention also provides a kind of preparation method of this Chinese medicine composition, comprises the steps:

(1) to be broken into impalpable powder standby for Radix Angelicae Sinensis powder;

(2) Radix Salviae Miltiorrhizae, Sargassum, Rhizoma Cyperi, the Radix Astragali, Rhizoma Chuanxiong, Semen Coicis, Thallus Laminariae (Thallus Eckloniae), Radix Achyranthis Bidentatae, Rhizoma Dioscoreae, Radix Notoginseng, Radix Paeoniae Rubra, Radix Curcumae, Semen Citri Reticulatae decoct with water secondary, each 3 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder, drying, be ground into fine powder, make granule, capsule and tablet with pharmaceutically acceptable carrier.

Pharmaceutical composition of the present invention can with receivable carrier pharmaceutically, for example: filler such as starch, microcrystalline Cellulose etc.; Binding agent such as vitamin derivative, starch etc.; Mode by granule, capsule, tablet oral administration is used.

Chinese medicine composition of the present invention has effects such as warming spleen and stomach for dispelling cold, spleen invigorating dry, detoxicating and resolving stagnation of pathogens, nourishing the liver and kidney, is used for diseases such as lower abdomen that ovarian cyst causes or the inflation of bone nest portion, tenesmus, stomachache, menoxenia.

The specific embodiment

Following examples are used to illustrate the present invention, but are not used for limiting the scope of the invention.

Embodiment: 1 Chinese medicinal composition granules of the present invention

(1) to be ground into impalpable powder standby for Radix Angelicae Sinensis 260g;

(2) Radix Salviae Miltiorrhizae 80g, Sargassum 160g, Rhizoma Cyperi 180g, Radix Astragali 160g, Rhizoma Chuanxiong 180g, Semen Coicis 130g, Thallus Laminariae (Thallus Eckloniae) 260g, Radix Achyranthis Bidentatae 180g, Rhizoma Dioscoreae 80g, Radix Notoginseng 200g, Radix Paeoniae Rubra 160g, Radix Curcumae 160g, Semen Citri Reticulatae 230g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder, drying is ground into fine powder, add dextrin 800g, lactose 200g, mixing, with 75% ethanol wet granulation, pack promptly.

Embodiment 2: Chinese medicinal composition capsules agent of the present invention

(1) to be ground into impalpable powder standby for Radix Angelicae Sinensis 260g;

(2) Radix Salviae Miltiorrhizae 80g, Sargassum 160g, Rhizoma Cyperi 180g, Radix Astragali 160g, Rhizoma Chuanxiong 180g, Semen Coicis 130g, Thallus Laminariae (Thallus Eckloniae) 260g, Radix Achyranthis Bidentatae 180g, Rhizoma Dioscoreae 80g, Radix Notoginseng 200g, Radix Paeoniae Rubra 160g, Radix Curcumae 160g, Semen Citri Reticulatae 230g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, and got supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, add above-mentioned fine powder, drying is ground into fine powder, adds dextrin 1200g, mixing, in the capsulae vacuus of packing into promptly.

Embodiment 3: Chinese medicine composition tablet of the present invention

(1) to be ground into impalpable powder standby for Radix Angelicae Sinensis 260g;

(2) Radix Salviae Miltiorrhizae 80g, Sargassum 160g, Rhizoma Cyperi 180g, Radix Astragali 160g, Rhizoma Chuanxiong 180g, Semen Coicis 130g, Thallus Laminariae (Thallus Eckloniae) 260g, Radix Achyranthis Bidentatae 180g, Rhizoma Dioscoreae 80g, Radix Notoginseng 200g, Radix Paeoniae Rubra 160g, Radix Curcumae 160g, Semen Citri Reticulatae 230g decoct with water secondary, each 2 hours, filter, merging filtrate, left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder, dry, be ground into fine powder, add starch 300g, microcrystalline Cellulose 100g and low substituted cellulose 100g, with 70% ethanol wet granulation, drying, tabletting, coating are promptly.

Claims (4)

1, a kind of Chinese medicine composition for the treatment of ovarian cyst is to be made by effective ingredient and/or pharmaceutically acceptable carrier, it is characterized in that described effective ingredient is made by weight by following raw materials according.

Radix Astragali 10-20 part Radix Salviae Miltiorrhizae 5-10 part Radix Angelicae Sinensis 20-30 part

Rhizoma Chuanxiong 15-20 part Semen Coicis 10-15 part Thallus Laminariae (Thallus Eckloniae) 20-30 part

Sargassum 10-20 part Radix Achyranthis Bidentatae 15-20 part Rhizoma Dioscoreae 5-10 part

Radix Notoginseng 15-25 part Radix Paeoniae Rubra 10-20 part Rhizoma Cyperi 15-20 part

Radix Curcumae 10-20 part Semen Citri Reticulatae 20-25 part.

2, Chinese medicine composition as claimed in claim 1 is characterized in that described effective ingredient made by weight by following raw materials according.

26 parts of 8 parts of Radix Angelicae Sinensis of 16 parts of Radix Salviae Miltiorrhizaes of the Radix Astragali

26 parts of 13 parts of Thallus Laminariae (Thallus Eckloniae)s of 18 parts of Semen Coiciss of Rhizoma Chuanxiong

8 parts of 18 portions of Rhizoma Dioscoreaes of 16 parts of Radix Achyranthis Bidentataes of Sargassum

18 parts of 16 portions of Rhizoma Cyperis of 20 parts of Radix Paeoniae Rubra of Radix Notoginseng

23 parts of 16 parts of Semen Citri Reticulataes of Radix Curcumae.

3,, it is characterized in that described Chinese medicine composition can be made into granule, capsule and tablet as the arbitrary described Chinese medicine composition of claim 1-2.

4, a kind of preparation method as the arbitrary described Chinese medicine composition of claim 1-3 comprises the steps:

(1) to be broken into impalpable powder standby for Radix Angelicae Sinensis powder;

(2) Radix Salviae Miltiorrhizae, Sargassum, Rhizoma Cyperi, the Radix Astragali, Rhizoma Chuanxiong, Semen Coicis, Thallus Laminariae (Thallus Eckloniae), Radix Achyranthis Bidentatae, Rhizoma Dioscoreae, Radix Notoginseng, Radix Paeoniae Rubra, Radix Curcumae, Semen Citri Reticulatae decoct with water secondary, each 3 hours, filter, merging filtrate left standstill 48 hours, get supernatant, it is the thick paste of 1.20 (60 ℃) that concentrating under reduced pressure becomes relative density, adds above-mentioned fine powder, drying, be ground into fine powder, make granule, capsule and tablet with pharmaceutically acceptable carrier.