Background technology
Comprise 6 stages such as adult, ovum, miracidium, born of the same parents' larva of a tapeworm or the cercaria of a schistosome, cercaria and virgin worm the bilharzial history of life.Infect bilharzial people or other mammal is discharged worm's ovum from ight soil, if fecal pollution water, worm's ovum is brought in the water, hatches miracidium in water.Miracidium can freely move about in water, and initiatively pierces in the oncomelania body in the water, develops into mother sporocyst, carries out vegetative propagation, produces daughter sporocyst.Daughter sporocyst through once breeding, produces a large amount of cercarias again, and cercaria leaves oncomelania and freely moves about in water.In the bilharzial history of life, two hosts are arranged, one is called the definitive host by the people of adult parasitism and other mammal, and many kinds of mammals all can become bilharzial definitive host; Another is the intermediate host by the oncomelania of larva parasitism, and oncomelania is unique intermediate host of Schistosoma japonicum.
At present, killing bilharzial method is to adopt to kill blood fluke intermediate host oncomelania, cuts off bilharzial existence chain.And the chemicals spiral shell that goes out is one of effective measures of control oncomelania.Niclosamidum is the unique chemical snail killing agent of world health organisation recommendations, but the 50% bayluscid wetting powder that generally uses at present, exist poorly soluble, suspensibility is low, very easily stop up defective such as drug-spraying instrument.Simultaneously, with the niclosamidum spiral shell that goes out, oncomelania is usually dried up to swash, and escapes drug effect, and this medicine is to the toxic effect of fish, and costs an arm and a leg.The promotion and application of niclosamidum have seriously been restricted.
" the Chinese People's Political Consultative Conference's newspaper " the medical board Zhong Weikun of B1 version Wuhan University professor mentioned in " prevention and cure of schistosomiasis: the spiral shell difficulty of going out is proved effective " literary composition according on August 17th, 2005, and " killing oncomelania, its difficulty equal to eliminate a species gene.Use snail control with drugs, also can pollution in wide area soil, water quality, aquatic animals and plants such as fish are poisoned big, the composition that has enters human body with edible aquatic animals and plants, can become the cancer mutagen, still not having at present long-range science tracking evaluation system and using various snail killing agents in a large number, be comparison danger ".
Summary of the invention
The purpose of this invention is to provide a kind of to the human and animal excreta harmless treatment, easy to use, cost is low, environmentally safe can be effectively from the medicine of source blocking-up schistosome ovum and the using method of this medicine.
For achieving the above object, the technical scheme that is adopted is:
Nitrolim is used to kill schistosome ovum.
The mixture of nitrolim and calcium oxide is used to kill schistosome ovum.
The mixture of nitrolim and calcium oxide is used to kill schistosome ovum, it is characterized in that in the said mixture, and the weight ratio of nitrolim and calcium oxide is 1: 1-0.5.
Nitrolim is used to kill the using method of schistosome ovum;
In people, animal ight soil, add the nitrolim of human and animal excreta weight 0.25-2%, placed 2 hours to 168 hours, just can kill schistosome ovum.
The mixture of nitrolim and calcium oxide is used to kill the using method of schistosome ovum;
In people, animal ight soil, add nitrolim and the calcium oxide of human and animal excreta weight 0.5-4%, placed 2 hours to 168 hours, just can kill schistosome ovum.
The mixture of nitrolim and calcium oxide is used to kill the using method of schistosome ovum, it is characterized in that in the said mixture, and the weight ratio of nitrolim and calcium oxide is 1: 1-0.5.
By a large amount of evidences, the present invention has following characteristics:
1, can carry out harmless treatment to human and animal excreta, environmentally safe can be imitated the bilharzial growth of blocking-up from the source, and can increase the fertilizer efficiency of human and animal excreta.
If block bilharzial growing chain from the source, schistosomiasis just can't be propagated, thereby can utterly destroy schistosomiasis, is the best approach that substitutes the spiral shell chemicals niclosamidum that goes out.The employing niclosamidum goes out in the spiral shell process, the subject matter that occurs has: one, country drops into a large amount of funds, for providing niclosamidum, the epidemic-stricken area is used to the spiral shell that goes out, but because niclosamidum is to toxic effects of economic aquatic product such as fish, shrimp, crabs, make the various economic aquatic products thing large tracts of land death in the pond, be subjected to the resistance at aquaculture family.We understand tool, and the niclosamidum that the aquaculture family usually provides free country is mixed with the very low solution of concentration, be used for the pond sterilization, and this concentration do not have molluscicide effect at all, and this is the main cause that causes oncomelania to spread unchecked in large tracts of land in recent years; When two, going out spiral shell with niclosamidum, oncomelania is usually dried up to swash, and escapes drug effect, be cause the sn ail control effect difference former therefore two; Three, because a large amount of uses of niclosamidum, also can pollution in wide area soil, water quality, the composition that has simultaneously enters human body with edible aquatic animals and plants, can become the cancer mutagen, and this is to cause three of main cause that several years large tracts of land spread unchecked.
By experimental results demonstrate, utilize nitrolim or nitrolim and calcium oxide to kill schistosome ovum, on the one hand, kill the effective of schistosome ovum, just schistosome ovum all can be killed to 168 hours in 2 hours, so just blocked blood fluke from the source; On the other hand,, when killing schistosome ovum, can improve the fertilizer efficiency of human and animal excreta, replenish calcium fertilizer deficiency in the soil, environment, soil are not had influence because nitrolim is a kind of slow release fertilizer.
2, present, the output of domestic nitrolim is about ten thousand tons of 30-40, and production scale had the trend of quick expansion in recent years, and as the elimination worm's ovum of sucking blood, alternative niclosamidum becomes possibility, and consumption is few, can reduce the expenses for prevention and control of schistosomiasis with nitrolim.
3, nitrolim can decompose noresidue fully in water.Nitrolim resolves into cyanogen ammonia hydrogen calcium and slaked lime in water, cyanogen ammonia hydrogen calcium finally decomposes ammonification and carbonic acid gas, can the aquatic organism in environment and fish pond, the lake not impacted.In the rice field, catabolite can be utilized by plant absorbing as nitrogenous fertilizer.Therefore, when utilizing nitrolim killing schistosome ovum, provide nitrogenous fertilizer again, not only economy but also environmentally friendly.
Embodiment
Embodiment 1:
Contain in the people, animal ight soil of schistosome ovum at 100kg, drop into the nitrolim of 0.25kg, placed about 120 hours, detect and do not find schistosome ovum alive.
Embodiment 2:
Contain in the excrement of animals of schistosome ovum at 100kg, add the nitrolim of 0.25kg and the calcium oxide of 0.25kg, mix all back placements about 120 hours, detect the schistosome ovum that discovery is lived.
Embodiment 3-10:
On the basis of embodiment 1, change the usage amount of nitrolim, it kills the situation such as the following table of schistosome ovum:
Sequence number |
Human faecal mass (kg) |
Nitrolim (kg) |
Standing time (hour) |
Effect |
Embodiment 3 |
100 |
0.5 |
2 |
12% kills |
Embodiment 4 |
100 |
0.5 |
12 |
26% kills |
Embodiment 5 |
100 |
0.5 |
24 |
69% kills |
Embodiment 6 |
100 |
0.5 |
120 |
100% kills |
Embodiment 7 |
100 |
1.0 |
2 |
20% kills |
Embodiment 8 |
100 |
1.0 |
12 |
30% kills |
Embodiment 9 |
100 |
1.0 |
24 |
72% kills |
Embodiment 10 |
100 |
1.0 |
120 |
100% kills |
Embodiment 11-18:
On the basis of embodiment 1, change the usage amount of nitrolim, it kills the situation such as the following table of schistosome ovum:
Sequence number |
Animal wastes (kg) |
Nitrolim (kg) |
Standing time (hour) |
Effect |
Embodiment 11 |
100 |
0.5 |
2 |
10% kills |
Embodiment 12 |
100 |
0.5 |
12 |
23% kills |
Embodiment 13 |
100 |
0.5 |
24 |
65% kills |
Embodiment 14 |
100 |
0.5 |
120 |
100% kills |
Embodiment 15 |
100 |
1.0 |
2 |
18% kills |
Embodiment 16 |
100 |
1.0 |
12 |
29% kills |
Embodiment 17 |
100 |
1.0 |
24 |
71% kills |
Embodiment 18 |
100 |
1.0 |
120 |
100% kills |
Embodiment 19-26:
On the basis of embodiment 2, change the usage amount of nitrolim, it kills the situation such as the following table of schistosome ovum:
Sequence number |
Human faecal mass (kg) |
Nitrolim+calcium oxide (kg) |
Standing time (hour) |
Effect |
Embodiment 19 |
100 |
0.5+0.5 |
2 |
18% kills |
Embodiment 20 |
100 |
0.5+0.5 |
12 |
32% kills |
Embodiment 21 |
100 |
0.5+0.5 |
24 |
74% kills |
Embodiment 22 |
100 |
0.5+0.5 |
120 |
100% kills |
Embodiment 23 |
100 |
1.0+0.5 |
2 |
23% kills |
Embodiment 24 |
100 |
1.0+0.5 |
12 |
34% kills |
Embodiment 25 |
100 |
1.0+0.5 |
24 |
78% kills |
Embodiment 26 |
100 |
1.0+0.5 |
120 |
100% kills |
Embodiment 27-34:
On the basis of embodiment 2, change the usage amount of nitrolim, it kills the situation such as the following table of schistosome ovum:
Sequence number |
Animal wastes (kg) |
Nitrolim+calcium oxide (kg) |
Standing time (hour) |
Effect |
Embodiment 27 |
100 |
0.5+0.5 |
2 |
14% kills |
Embodiment 28 |
100 |
0.5+0.5 |
12 |
29% kills |
Embodiment 29 |
100 |
0.5+0.5 |
24 |
71% kills |
Embodiment 30 |
100 |
0.5+0.5 |
120 |
100% kills |
Embodiment 31 |
100 |
1.0+0.8 |
2 |
26% kills |
Embodiment 32 |
100 |
1.0+0.8 |
12 |
37% kills |
Embodiment 33 |
100 |
1.0+0.8 |
24 |
88% kills |
Embodiment 34 |
100 |
1.0+0.8 |
120 |
100% kills |
By the foregoing description as can be seen, the mixture of nitrolim or nitrolim and calcium oxide can be killed schistosome ovum effectively.
When the usage amount of nitrolim during at 1-2kg, best results.