CN101229587A - Biological ceramics titanium base compound material and manufacturing method thereof - Google Patents
Biological ceramics titanium base compound material and manufacturing method thereof Download PDFInfo
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- CN101229587A CN101229587A CNA2008100263783A CN200810026378A CN101229587A CN 101229587 A CN101229587 A CN 101229587A CN A2008100263783 A CNA2008100263783 A CN A2008100263783A CN 200810026378 A CN200810026378 A CN 200810026378A CN 101229587 A CN101229587 A CN 101229587A
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Abstract
The invention relate to a method for preparing powder metallurgy of bioceramic titanium matrix composite material, which is characterized in that: (1) metal titanium powder with granularity of 5Mum-100Mum and nano-sized hydroxyapatite powder with the granularity less than 100nm are mixed uniformly, wherein, volume fraction of the nano-sized hydroxyapatite powder is 1 percent to 10 percent; (2) the mixing powder is shaped by using isostatic pressing and is vacuum sintered under 1050 DEG C to 1200 DEG C to prepare the bioceramic titanium matrix composite material. bioactivity of the prepared composite material is higher than that of pure titanium material prepared by a powder metallurgy method; bending strength of the composite material is larger than 140MPa, which is higher than or equal to that of human bones; compressive elastic modulus of the composite material is 7.9GPa to18.5GPa, which is close to that of the human bones. The invention can be used for preparing biological replacement (restoration) bodies which are used by hard tissues such as human skeletons, teeth, and so on.
Description
Technical field
The present invention relates to the bio-medical metal-base composites, specifically is biological ceramics titanium base compound material and preparation method thereof.
Background technology
At present biological hard tissues such as skeleton and tooth mostly are rolling greatly or the cast titanium material with replacing (reparation) material, and that the titanium material has is corrosion-resistant, intensity is high and characteristics such as biocompatibility.But the elastic modelling quantity of rolling or cast titanium material is apparently higher than the human body bone, thereby reduced the biomechanical compatibility of material, limited the application of titanium material.The titanium material of powder metallurgy process preparation is because of having an amount of hole, thereby makes the elastic modelling quantity decline of material, and the biomechanical compatibility of material makes moderate progress.Yet the titanium material biologically active of powder metallurgy process preparation is weak, and the biomechanical compatibility of material is still waiting to improve.
Summary of the invention
The object of the present invention is to provide a kind of method for preparing powder metallurgy of biological ceramics titanium base compound material, the titanium material biologically active that solves the prior art existence is weak the elastic modelling quantity problem of higher of material.
The present invention also aims to provide the biological ceramics titanium base compound material of described method preparation.
The preparation method of biological ceramics titanium base compound material of the present invention comprises the steps:
(1) being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder of 100nm, and wherein the volume fraction of nanometer hydroxyapatite is 1%～10%, preferred 1～9%, and further preferred 2～4.9%;
(2) mixed-powder adopts hydrostatic pressing, vacuum-sintering then, and sintering temperature is 1050 ℃～1200 ℃.
The design considerations and the main feature of biological ceramics titanium base compound material of the present invention and preparation method thereof are as follows: titanium powder adds after the nanometer hydroxyapatite powder of biologically active, the composite biologically active of powder metallurgy preparation improves, and the composite biologically active is higher than the pure titanium material of powder metallurgy preparation; Titanium powder adds after the nanometer hydroxyapatite powder, has increased the porosity of the composite of powder metallurgy preparation, has further reduced the elastic modelling quantity of composite, and composite modulus of elasticity in comperssion 7.9GPa～18.5GPa is approaching with the human body bone; Titanium powder adds after the nanometer hydroxyapatite powder, and the porosity of the composite of powder metallurgy preparation increases, and make the intensity of composite descend to some extent, but the composite bending strength still is higher than or is equivalent to the human body bone greater than 140MPa.Biological ceramics titanium base compound material can be used for preparing sclerous tissueses such as skeleton and tooth biological replacement (reparation) body.
The specific embodiment
Embodiment 1: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 10%) of 100nm, mixed-powder adopts hydrostatic pressing, 1100 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 154MPa, modulus of elasticity in comperssion 9.3GPa.
Embodiment 2: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 2%) of 100nm, mixed-powder adopts hydrostatic pressing, 1100 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 860MPa, modulus of elasticity in comperssion 17GPa.
Embodiment 3: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 4.9%) of 100nm, mixed-powder adopts hydrostatic pressing, 1150 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 435MPa, modulus of elasticity in comperssion 14GPa.
Embodiment 4: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 10%) of 100nm, mixed-powder adopts hydrostatic pressing, 1050 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 144MPa, modulus of elasticity in comperssion 7.9GPa.
Embodiment 5: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 9%) of 100nm, mixed-powder adopts hydrostatic pressing, 1100 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 170MPa, modulus of elasticity in comperssion 9.8GPa.
Embodiment 6: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 1%) of 100nm, mixed-powder adopts hydrostatic pressing, 1200 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 950MPa, modulus of elasticity in comperssion 18.5GPa.
Embodiment 7: being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder (nanometer hydroxyapatite powder addition volume fraction 3%) of 100nm, mixed-powder adopts hydrostatic pressing, 1200 ℃ of vacuum-sinterings, prepare biological ceramics titanium base compound material then.The biologically active of composite is higher than the pure titanium material of powder metallurgy process preparation, composite bending strength 720MPa, modulus of elasticity in comperssion 16GPa.
Claims (4)
1. the method for preparing powder metallurgy of a biological ceramics titanium base compound material is characterized in that comprising the steps:
(1) being the metallic titanium powder of 5 μ m～100 μ m and granularity with granularity mixes less than the nanometer hydroxyapatite powder of 100nm, and wherein the nanometer hydroxyapatite volume fraction is 1%～10%;
(2) mixed-powder adopts hydrostatic pressing, vacuum-sintering then, and sintering temperature is 1050 ℃～1200 ℃.
2. method according to claim 1, the volume fraction that it is characterized in that described nanometer hydroxyapatite is 1%～9%.
3. method according to claim 2, the volume fraction that it is characterized in that described nanometer hydroxyapatite is 2%～4.9%.
4. the biological ceramics titanium base compound material for preparing of each described method of claim 1～3.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008100263783A CN101229587A (en) | 2008-02-20 | 2008-02-20 | Biological ceramics titanium base compound material and manufacturing method thereof |
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| CNA2008100263783A CN101229587A (en) | 2008-02-20 | 2008-02-20 | Biological ceramics titanium base compound material and manufacturing method thereof |
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| CN101229587A true CN101229587A (en) | 2008-07-30 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101967613A (en) * | 2010-10-28 | 2011-02-09 | 天津大学 | Titanium-based metal glass/hydroxyapatite composite material and preparation method thereof |
| CN104436297A (en) * | 2014-11-28 | 2015-03-25 | 中国船舶重工集团公司第七○二研究所 | Power material for manufacturing artificial bone and preparation method of power material |
| CN105251057A (en) * | 2015-10-30 | 2016-01-20 | 昆明理工大学 | Preparation method of porous titanium/hydroxyapatite composite material |
| WO2017152541A1 (en) * | 2016-03-11 | 2017-09-14 | 安徽拓宝增材制造科技有限公司 | Composite biomedical implant material and preparation method therefor |
| CN111299572A (en) * | 2019-11-28 | 2020-06-19 | 天钛隆（天津）金属材料有限公司 | Production method of titanium and titanium alloy seamless tube |
| CN115591013A (en) * | 2022-10-14 | 2023-01-13 | 中山大学附属口腔医院（Cn） | Metal-ceramic mixed gradient 3D printing material and preparation method and application thereof |
-
2008
- 2008-02-20 CN CNA2008100263783A patent/CN101229587A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101967613A (en) * | 2010-10-28 | 2011-02-09 | 天津大学 | Titanium-based metal glass/hydroxyapatite composite material and preparation method thereof |
| CN101967613B (en) * | 2010-10-28 | 2012-05-09 | 天津大学 | Titanium-based metal glass/hydroxyapatite composite material and preparation method thereof |
| CN104436297A (en) * | 2014-11-28 | 2015-03-25 | 中国船舶重工集团公司第七○二研究所 | Power material for manufacturing artificial bone and preparation method of power material |
| CN104436297B (en) * | 2014-11-28 | 2016-02-03 | 中国船舶重工集团公司第七○二研究所 | Dusty material of a kind of manufacture of intraocular bone and preparation method thereof |
| CN105251057A (en) * | 2015-10-30 | 2016-01-20 | 昆明理工大学 | Preparation method of porous titanium/hydroxyapatite composite material |
| WO2017152541A1 (en) * | 2016-03-11 | 2017-09-14 | 安徽拓宝增材制造科技有限公司 | Composite biomedical implant material and preparation method therefor |
| CN111299572A (en) * | 2019-11-28 | 2020-06-19 | 天钛隆（天津）金属材料有限公司 | Production method of titanium and titanium alloy seamless tube |
| CN111299572B (en) * | 2019-11-28 | 2022-05-03 | 天钛隆（天津）金属材料有限公司 | Production method of titanium and titanium alloy seamless tube |
| CN115591013A (en) * | 2022-10-14 | 2023-01-13 | 中山大学附属口腔医院（Cn） | Metal-ceramic mixed gradient 3D printing material and preparation method and application thereof |
| CN115591013B (en) * | 2022-10-14 | 2024-01-02 | 中山大学附属口腔医院 | Metal-ceramic mixed gradient 3D printing material and preparation method and application thereof |
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