CN101172051A - Device for crushing and taking out thrombus - Google Patents

Device for crushing and taking out thrombus Download PDF

Info

Publication number
CN101172051A
CN101172051A CN 200610123099 CN200610123099A CN101172051A CN 101172051 A CN101172051 A CN 101172051A CN 200610123099 CN200610123099 CN 200610123099 CN 200610123099 A CN200610123099 A CN 200610123099A CN 101172051 A CN101172051 A CN 101172051A
Authority
CN
China
Prior art keywords
catheter
thrombus
balloon
mesh
filter
Prior art date
Application number
CN 200610123099
Other languages
Chinese (zh)
Inventor
朱正兵
Original Assignee
朱正兵
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 朱正兵 filed Critical 朱正兵
Priority to CN 200610123099 priority Critical patent/CN101172051A/en
Publication of CN101172051A publication Critical patent/CN101172051A/en

Links

Abstract

本发明公开了一种用于粉碎和取出血栓的装置,它包括导丝、交叉网丝、滤器、牵引装置、多球囊导管和外壳导管。 The present invention discloses a pulverizing apparatus and taken for thrombus, which comprises a guidewire, the crossover wire, filter, traction devices, multi-balloon catheter and catheter housing. 多球囊导管的远端柔软部分呈串珠样排列有多个球囊;交叉网丝和滤器被压缩套在球囊导管的远端部分并覆盖球囊,充盈球囊,撑开交叉网丝和滤器,粉碎并取出小血管中血栓或其他栓子。 Multiple flexible distal portion of the balloon catheter beaded plurality of balloons arranged; crossover and filter mesh sleeve is compressed in a distal portion of the balloon catheter and covers the balloon, filling the balloon, the expansion and cross mesh filter, and remove the crushed small vessels thrombi or other emboli.

Description

用于粉碎和取出血栓的装置 Means for pulverizing and removing the thrombus

技术领域 FIELD

本发明涉及用于粉碎并取出血管内或其他解剖学通道内的新鲜血栓、动脉粥样硬化斑块或其他物体的装置。 The present invention relates to a pulverized fresh thrombus, and intravascular or in other anatomical passageway, atherosclerotic plaque or other object extraction means.

背景技术 Background technique

随着生活水平的改善,心脑血管疾病发病率逐年提高,成为人类三大死亡原因之一。 With the improvement of living standards, the incidence of cardiovascular and cerebrovascular diseases increase year by year, becoming one of the three major causes of death in humans. 其中脑血管疾病的发病率、患病率、死亡率、病残率和复发率均高。 Wherein the incidence of cerebrovascular diseases, morbidity, mortality, morbidity and recurrence rates. 中国脑血管病流行病学的调査主要结果如下:发病率:136〜441/10万人口/年(163.2〜1529.2万/年),其中,脑梗塞占脑卒中的75%;患病率:280〜1285/10万人口(336〜1529. 2万/年);死亡率:59~281/10 万人口/年(70.8〜337.2万/年)平均130/10万人/年(156万/年);病残率:60-80%。 The main results of the epidemiological investigation of China of cerebrovascular disease are as follows: Incidence: 136~441 / 100,000 population / year (163.2~1529.2 Wan / year), which accounted for cerebral stroke 75%; prevalence: 280~1285 / 100,000 population (336~1529 20,000 / yr.); mortality rate: 59 to 281 / 100,000 population / year (70.8~337.2 Wan / year) average of 130/10 million / year (1.56 million / years); morbidity: 60-80%. 它极大地危害着人类的健康,是医学界面临的重大课题。 It greatly endanger human health is a major issue facing the medical profession. 一般来说,成年晚期发病的主要原因多为动脉粥样硬化性血栓闭塞疾病。 In general, mainly due to late adulthood onset of multiple thrombosis atherosclerotic occlusive disease. .

其治疗目的:治疗重点放在恢复或积极增加缺血区的灌流,采取溶栓或抗凝及脑保护剂, 调整血压,既要防止血压过高引起溶栓过程中出血,又要避免血压过低出现灌流不足,加重缺血症状。 Its therapeutic purposes: treatment focuses on restoring or increasing the active perfusion of the ischemic area, take thrombolytic agent or anticoagulant and brain protection, adjust blood pressure, it is necessary to prevent high blood pressure caused by bleeding during thrombolytic therapy, but also to avoid excessive blood pressure low appear inadequate perfusion, increased ischemic symptoms.

增加脑灌注的办法主要有经动脉和静脉溶栓药物治疗和经皮插管介入治疗方法。 Ways to increase cerebral perfusion main arterial and venous thrombolytic therapy and percutaneous catheter intervention treatment. 目前临床常用溶栓药物有尿激酶、组织纤溶酶原激活剂(TPA)等,抗凝药物有肝素、华法林等。 Thrombolytic drugs currently used in the clinic urokinase, tissue plasminogen activator (TPA) and other anticoagulant drugs heparin and warfarin. 该方法在治疗过程中药物剂量过大会并发脑出血,剂量过小达不到溶栓的目的,并且有血管再通率不高,溶栓治疗时间过长的缺点,从而降低治疗效果。 The pharmaceutical dosage Excessive cerebral hemorrhage in the course of treatment, the dose is too small to reach the purpose of thrombolysis, and vascular recanalization rate is not high, the disadvantages of long time thrombolytic therapy, thereby decreasing the therapeutic effect.

经皮插管介入治疗方法目前常已有血栓取出/破坏导管(如具有吸力头的吸入型导管), 血栓捕获型导管(如远端具有血栓捕获容器的导管),血栓破坏装置(导管远端含有超声探或激光头),将上述器械装置远端超过或靠近血栓,将血栓捕获、破坏或消融,起到再通血管的目的。 Percutaneous treatment cannula often present existing thrombus removed / destroyed catheter (e.g., a suction head having a suction catheter), thrombus capturing catheter (e.g., the distal end of a catheter thrombus capturing container), thrombus destruction device (catheter distal end containing ultrasound probe or laser head), the above-described means the instrument beyond the distal end or near the thrombus, the thrombus capturing, destruction or ablation, serve the purpose of vascular recanalization. 现有的血栓捕获型导管各有其优缺点,因其柔性不够,对较大血管内血栓捕获效果较好,但对走行迂曲的颅内血管则进入困难,难以实施。 Conventional thrombus capturing catheter has advantages and disadvantages, because of its flexible enough, the effect of trapping the thrombus preferably larger vessels, the intracranial blood vessels but tortuous is difficult to enter, difficult to implement.

发明内容 SUMMARY

针对现有技术的缺点,本发明的目的是提供一种用于粉碎和取出血栓的装置,用于在血管小动脉中,特别是心脏或弯曲的脑血管中取出血栓或其他栓子,避免血管阻塞进一步加重, 降低死亡率,减轻致残程度,提高生活质量。 For the disadvantages of the prior art, an object of the present invention is to provide a pulverizing apparatus and taken for thrombus, a blood vessel for small arteries, especially the heart or curved cerebrovascular thrombus or other embolus removed, to avoid vascular blocking further increase, reduce mortality, reduce the degree of disability and improve quality of life.

为了实现上述目的,本发明的技术方案为: 一种用于粉碎和取出血栓的装置,它包括导丝、管状交叉网丝、滤器、牵引装置、球囊导管和外壳导管。 To achieve the above object, the technical solution of the present invention is: one kind of crushing and extraction apparatus for thrombus, which comprises a guidewire, the tubular cross-mesh, filter, the traction device, the balloon catheter and catheter housing. 球囊导管的远端柔软部分呈串 A distal portion of the balloon catheter was soft string

珠样排列有多个球囊;管状交叉网丝的远端与滤器相联接,近端与牵引装置相联接,管状交叉网丝与滤器被压縮套在球囊导管的远端部分并覆盖球囊,导丝轴向穿过球囊导管,导丝、 A plurality of balloon-like beads are arranged; the distal end of the tubular filter with a crossover wire coupled to the proximal end coupled to the traction means, the tubular mesh and cross filter sleeve is compressed in the distal portion of the balloon catheter and covers the ball balloon, guide wire axially through the balloon catheter, guide wire,

牵引装置和球囊导管的近端部分可移动地套有外壳导管。 Traction means and proximal portion of the balloon catheter with a housing movably sleeved conduit.

所述管状交叉网丝3是由薄壁的不锈钢管或Ni-Ti合金、Cu-Zn-Al合金管激光雕刻而成, 或由3、 4、 6、 8根或更多根螺旋状相互交叉的Ni-Ti合金细丝、Cu-Zn-Al合金细丝、不锈钢细丝、有弹性的高分子医用塑料或纤维细丝或者其他金属细丝编织而成,管状交叉网丝长约2. 0、 2.5、 3.0、 3.5、 4.0、 4.5、 5. 0厘米不等,直径为3. 0、 3.5、 4.0、 4.5、 5.0、 6.0 毫米不等,可以依据长度和直径分为不同型号。 The tubular cross mesh tube 3 is made thin-walled stainless steel or Ni-Ti alloy, Cu-Zn-Al alloy pipe laser carved, or a 3, 4, 6, 8 or more spirally interdigitated root the Ni-Ti alloy filaments, Cu-Zn-Al alloy filaments, steel filaments, flexible medical plastic or polymer or other fiber filaments woven metal filaments, tubular cross mesh about 2.0 , 2.5, 3.0, 3.5, 4.0, 4.5, ranging from 5.0 cm, a diameter of 3.0, 3.5, 4.0, 4.5, 5.0, 6.0 mm range, can be divided into different types depending on the length and diameter.

所述滤器分为两部分,近段部分为管状,末端为漏斗状,由3、 4、 6、 8或多根轴对称结构的金属丝构成骨架,骨架外面套有医用塑料薄膜,该薄膜上设有众多小孔,该小孔的直径为100至500微米,它可以既能让血液通过,又可以阻止血栓或脱落的粥样斑块通过。 The filter is divided into two portions, the proximal portion is tubular, the end of the funnel, a 3, 4, 6, 8 or the wire axes of symmetry constituting a skeleton structure, the skeleton sleeved outside medical plastic film, the film with many small holes, the hole diameter of 100 to 500 microns, which can not only allow blood to pass, but also to prevent thrombus or plaque by falling.

所述滤器也可以由更密集的交叉网丝构成,不需要薄膜,末端呈漏斗状,滤器网眼较管状交叉网丝的网眼小,滤器部分网眼短对角线为100-500微米,长对角线为500-3000微米,管状交叉网丝的网眼较大,长对角线为1000-5000微米,短对角线为500-3000微米。 The filter may be composed of a denser mesh cross, no film, funnel-shaped end, a tubular filter mesh smaller than a mesh of intersecting mesh, filter section 100-500 micron mesh short diagonal, the diagonal length lines 500 to 3,000 microns, the crossover wire mesh tubular large diagonal length 1,000 to 5,000 microns, 500 to 3000 microns shorter diagonal. 更密集的网眼也可以让血液通过的同时,阻止血栓或脱落的粥样斑块通过。 Denser mesh also allows simultaneous passage of blood to prevent blood clots or plaque shed by.

所述的球囊导管含2-5个串珠样排列的球囊,球囊导管由远端含多个球囊的柔软部分和具有一定张力的、柔性较远端差近端部分组成,单个球囊长度为5.0-10.0腿,直径为2-5mm, 球囊间隔为5.0-IO.O隱。 The balloon catheter containing 2-5 beaded arrangement balloon, a balloon catheter distal end portion having a plurality of flexible balloon having a certain tension, the flexible distal end than the proximal part differential, a single ball 5.0-10.0 balloon leg length, 2-5 mm in diameter, 5.0-IO.O balloon interval hidden. 球囊扩张的同时,撑开压附在上面的交叉网件和滤器。 Balloon while softened pressing member attached thereto, and crossover filters.

所述的多球囊导管远端柔性部分侧壁距远端一定距离有一导丝通过孔,导丝通过孔以远部分为双腔,其中一腔可通过导丝,另一腔与和导管近端部分及球囊相通并终止于远侧球囊, 使得远端口仅有一导丝出口,经末端接口注入造影剂充盈扩张多个串珠样排列的球囊,压附在球囊上的管状交叉网丝3和滤器2随之顺势扩张,血栓被挤碎并进入管状交叉网线3和滤器2内的球囊之间的空隙,使碎血栓位于管状交叉网线和滤器内。 The multi-balloon catheter distal end of the flexible distal end portion of the side wall a certain distance from a guidewire aperture, the guide wire lumen through the aperture beyond part, through which a guide wire lumen, and the other chamber with the catheter near end portion and a distal balloon and terminating in communication with the balloon, such that a distal guidewire port only outlet end by injecting the contrast agent filling the interface expandable balloon arranged in a plurality of beaded, cross-web is pressed against the tubular balloon 2 and 3 along the filter wire homeopathic expansion, thrombus be crushed into the gap between the balloon and the tubular crossover lines 3 and 2 in the filter, so that thrombus located within the broken lines and the tubular crossover filter.

所述的多球囊导管也可以为单腔导管,导管远端出口变细,仅能通过微导丝前段细软部分,粗硬部分被变细的出口卡住,单腔导管末端的导管柄设有主孔和侧孔,侧孔末端可接三通,主孔末端内腔为漏斗型,内置一与之相匹配的带中央孔的漏斗状橡皮圈,末端套上带中央孔螺帽。 The multi-balloon catheter can be a catheter, the distal end of the catheter is a single tapered outlet chamber, only through the micro-wire portion preceding soft, coarse stuck portion tapering outlet, the single lumen catheter tip catheter handle provided main and outer apertures, the side aperture may be tee end, the end of the main lumen is funnel-shaped hole, built with a central hole matches with a funnel-like rubber bands, put the end cap with a central aperture. 导丝可以通过有中央孔的螺帽和橡皮圈,拧紧螺帽的同时可以向主孔内腔挤压橡皮圈,縮小或关闭中央孔,以固定和控制导丝,并封闭球囊导管两端,然后经侧孔ll注入造影剂来充盈扩张多个串珠样排列的球囊,压附在球囊上的管状交叉网丝3和滤器2随之顺势扩张,血栓被挤碎并进入管状交叉网线3和滤器2内的球囊之间的空隙,使碎血栓位于管状 Guidewire may have a central aperture through the rubber band and a nut, the nut while tightening the rubber band can be pressed into the main chamber hole, reduced or closed central hole, to secure and control the guidewire and the balloon catheter is closed at both ends , and then through the side hole injecting contrast agent filling ll expandable balloon arranged in a plurality of beaded, cross is pressed against the tubular mesh 3 and the balloon on the filter 2 will take advantage of the expansion, thrombus and be crushed into the tubular crossover cable the gap between the balloon 3 and the inner filter 2, so that the tubular pieces thrombi

交叉网线和滤器内。 The crossover cable and filter.

所述的牵引装置为牵引导丝和连接件,连接件为3、4或6根轴对称结构的细金属丝组成, 该牵引导丝与球囊导管平行并通过轴对称结构的连接件细金属丝而与交叉网丝的近端相联接。 The traction means is a pull wire guide and the connecting member, the connecting member 3, 4, or 6 for the fine metal wires axisymmetric structure composed of the guide wire and the balloon catheter led in parallel through the connecting member and axial symmetry of the fine metal and cross wire coupled to the proximal end of mesh.

所述外壳导管为薄壁大内腔的导管。 The conduit housing is a thin, large-lumen catheter.

与现有技术相比,本发明可以在在小动脉血管(尤其脑血管)中取出血栓或其他栓子, 避免血管阻塞进一步加重,降低死亡率,减轻致残程度,提高生活质量。 Compared with the prior art, the present invention can be removed in a small thrombus or other embolic arteries (especially cerebral), avoiding a further increase vascular occlusion, reduce the mortality rate, reduce the degree of disability, improve the quality of life.

附图说明 BRIEF DESCRIPTION

下面结合附图对本发明作进一步的详细说明。 DRAWINGS The invention will be further described in detail below in conjunction.

图1为粉碎和取出血栓整体示意图,多球囊导管为单腔,滤器为更密集的交叉网丝。 Figure 1 is a schematic overall thrombosis pulverization and extraction, a single multi-lumen balloon catheter, the filter is denser mesh cross.

图2为粉碎和取出血栓整体示意图,球囊导管远段柔软部分为双腔,滤器为金属丝骨架外面套薄膜。 FIG 2 is a schematic overall thrombosis pulverization and extraction, the soft segment portion of the balloon catheter distal lumen, a filter is set outside the wire skeleton of the film.

图3为外面套有薄膜的滤器、管状交叉网丝、连结件和牵引导丝的示意图。 3 is a film out of filter sets, the tubular mesh cross, link member and the guide wire is a schematic view of the retractor.

图4为更密集的交叉网丝制成的滤器、管状交叉网丝、连结件和牵引导丝的示意图。 Filter is denser mesh made of intersecting FIG. 4, the tubular cross-mesh, and a coupling member schematic guide wire retractor.

图5为导丝通过孔以远部分为双腔的多球囊导管示意图。 FIG 5 is a guidewire lumen through the aperture beyond moiety is a schematic view of a multi-balloon catheter.

图6为单腔多球囊导管示意图。 6 is a schematic view of multiple single lumen balloon catheter.

具体实施方式 Detailed ways

请参阅图l、 2,本发明实施例一的装置包括:导丝l、滤器2、管状交叉网丝3、连接件4、牵引导丝5、球囊6、多球囊导管7、导丝通过孔8和外壳导管12。 L Referring to FIG, 2, an embodiment of the present invention, the apparatus comprising: a guide wire L, the filter 2, the tubular mesh 3 cross, connecting member 4, pull the guide wire 5, the balloon 6, 7 multi-balloon catheter, the guidewire 8 through the hole 12 and the housing conduit. 导丝l可以穿过血栓或脱落的动脉硬化斑块或其他栓塞物到达血栓远端足够远的部位;多球囊导管7沿导丝跟进, 穿过血栓并到达血栓远端足够远,其近端球囊应位于血栓近端;捕获血栓装置包括远端的滤器2和与之相连的管状交叉网丝3,管状交叉网丝3及滤器2覆盖所有球囊6,并被压縮套在球囊导管7远端,并随球囊导管7插入血栓内,充盈球囊6,管状交叉网丝3和滤器2随之扩张,血栓被压縮到球囊之间空隙处,同时被管状交叉网丝切碎,抽空球囊6并回抽球囊导管7,余下碎血栓位于管状交叉网丝3及滤器2内,回抽与支架相连的牵引导丝,同时推进 L guidewire may pass detached thrombus or atherosclerotic plaque or other embolic thrombosis distal end sufficiently far from reaching the site; multi-balloon catheter to follow the guidewire 7, and reaches the thrombus through the distal end of the thrombus far enough that proximal balloon should be located proximal thrombosis; thrombus capturing means comprises a filter 2 and a distal end of the tubular cross mesh 3 connected thereto, the tubular mesh 3 and cross the filter 2 covers all of the balloon 6, and is set in the compression 7 the distal end of the balloon catheter, with the balloon catheter and inserted thrombosis 7, filling the balloon 6, the tubular mesh 3 and the cross consequent expansion of the filter 2, the thrombus is compressed into the space between the balloons while being tubular crossbars net cut wire pieces, evacuated balloon 6 and 7 Withdrawing the balloon catheter, thrombus remaining pieces of the tubular mesh 3 and the filter cross-2, with the bracket attached to retractor Withdrawing the guide wire, while advancing

外鞘导管,使管状交叉网丝及其内部剩余碎血栓被收进外壳导管取出。 Catheter sheath, the tubular mesh and the cross-pieces remaining inside catheter thrombus incorporated into the housing removed.

请参阅图3、 4,管状交叉网丝由薄壁的不锈钢管或Ni-Ti合金、Cu-Zn-Al合金管激光雕刻而成,或由3、 4、 6、 8根或更多根螺旋状相互交叉的Ni-Ti合金细丝、Cu-Zn-Al合金细丝、不锈钢细丝、有弹性的高分子医用塑料或纤维细丝或者其他金属细丝编织而成,交叉网丝长约2.0、 2.5、 3.0、 3.5、 4.0、 4.5、 5.0厘米不等,直径为3.0、 3.5、 4.0、 4.5、 5.0、6.0毫米不等,可以依据长度和直径分为不同型号。 Refer to FIG. 3, 4, crossover wire tube tubular thin-walled stainless steel or Ni-Ti alloy, Cu-Zn-Al alloy pipe laser carved, or a 3, 4, 6, 8 or more helical root shaped Ni-Ti alloy filaments intersect each other, Cu-Zn-Al alloy filaments, steel filaments, flexible medical plastic or polymer fiber filaments or other filaments woven metal, wire crossover about 2.0 , 2.5, 3.0, 3.5, 4.0, 4.5, 5.0 centimeters, a diameter of 3.0, 3.5, 4.0, 4.5, 5.0, 6.0 mm range, can be divided into different types depending on the length and diameter. 其近端经连接件与牵引导丝相连,远端与滤器相连,牵引导丝与球囊导管并行。 Is connected via its proximal end connected to the guide member and the pull wire distal end is connected to the filter, pull the guide wire and balloon catheter in parallel.

参阅图3,滤器2分为两部分,近段部分为管状,末端为漏斗状,由多根轴对称结构的金属丝构成骨架,骨架外面套有薄膜,该薄膜上设有众多小孔,该小孔的直径为100至500 微米,它可以既能让血液通过,又可以阻止血栓或脱落的粥样斑块通过,滤器2远端中央有一孔,刚好可通过导管端头和导丝。 Referring to Figure 3, the filter 2 is divided into two portions, the proximal portion of the tubular end is funnel-shaped, a plurality of wires axially symmetric configuration skeleton, skeleton sets out a film, the film is provided with many small holes, the diameter holes 100 to 500 microns, which can not only allow blood to pass, but also to prevent thrombus or plaque by falling, the filter 2 has a distal end of the central hole, through just the tip of the catheter and guide wire. 滤器2长为2.0、 2.5、 3.0cm不等,直径与管状交叉网丝3相同,可以依据长度和直径分为不同型号。 2 the filter length is 2.0, 2.5, ranging same as the diameter of the tubular cross mesh 3 3.0cm, can be divided into different types depending on the length and diameter.

参阅图4,滤器2也可以由更密集的交叉网丝构成,不需要薄膜,近段为更密集的管状交叉网丝,末端呈漏斗状,管状交叉网丝由薄壁的不锈钢管或Ni-Ti合金、Cu-Zn-Al合金管激光雕刻而成,或由3、 4、 6、 8根或更多根螺旋状相互交叉的Ni-Ti合金细丝、Cu-Zn-Al合金细丝、不锈钢细丝、有弹性的高分子医用塑料或纤维细丝或者其他金属细丝编织而成,交叉网丝长约2.0、 2.5、 3.0厘米不等,直径与交叉网丝一致,可以依据长度和直径分为不同型号。 Referring to Figure 4, the filter 2 may be composed of a denser mesh cross, no film, as proximal tubular cross denser mesh, funnel-shaped end, the tubular mesh tube intersecting thin-walled stainless steel or Ni- Ti alloy, Cu-Zn-Al alloy pipe laser carved, or a 3, 4, 6, Ni-Ti alloy filaments 8 or more spirally interdigitated root, Cu-Zn-Al alloy filaments, stainless steel filaments, flexible medical plastic or polymer fiber filaments or other filaments woven metal, wire crossover about 2.0, 2.5, 3.0 centimeters, a diameter consistent with a crossover wire, can be based on length and diameter divided into different types. 滤器网眼为菱形、或便于压縮的多边形,滤器网眼较交叉网件的网眼小,滤器部分网眼短对角线为100-500微米,长对角线为500-3000微米,交叉网件的网眼较大,长对角线为1000-5000 微米,短对角线为500-3000微米。 Filter mesh rhombic, polygonal or facilitate compression, the filter mesh net meshes smaller than the cross-member, a mesh filter section 100-500 microns short diagonal, the diagonal length of 500 to 3000 microns, a mesh member crossover large diagonal length of 1,000 to 5,000 microns, 500 to 3000 microns shorter diagonal. 更密集的网眼也可以让血液通过的同时,阻止血栓或脱落的粥样斑块通过。 Denser mesh also allows simultaneous passage of blood to prevent blood clots or plaque shed by.

滤器2近端与管状交叉网丝3远端相连,两者连成一个整体,共同构成粉碎并血栓捕获结构,应根据不同的血管或血栓大小来选择相应型号的管状交叉网丝3和滤器2。 The proximal end of the filter 2 cross the tubular mesh 3 is connected to the distal end, the two together into a whole, constitute pulverized and thrombus capture structure, should select the appropriate type of tubular cross mesh depending on the size of the blood vessel or thrombus filters 2 and 3 .

连接件4由3、 4、 5、 6或8根轴对称结构的细金属丝或医用高分子塑料材料细丝构成, 与管状交叉网丝近端的3、 4、 5、 6或8个轴对称点及牵引导丝5相连,牵引导丝可由不锈钢丝制成。 4 by the connecting member 3, 4, 5, 6, or 8 or the fine wire filament medical polymer plastic material axially symmetric configuration, the proximal end of the tubular crossover wires 3, 4, 5, 6, or 8 shaft point of symmetry and the retractor 5 is connected to the guide wire, the guide wire pull wire may be made of stainless steel.

请参阅图5,多球囊导管7由远端的柔软部分和具有一定张力的、柔性较远端差的近段部分组成,导管柔软部分远端含3-5个串珠样排列的球囊,单个球囊长度为5. 0-10. Omm,直径为2-5mm,球囊间隔为5. 0-10. Om-m,,远端柔性部分侧壁距远端一定距离(5-30cm)有一微导丝通过孔8,导丝通过孔以远远部分为双腔,其中一腔可通过微导丝,另一腔与和导管末端及各球囊相通并终止于远侧球囊,使得远端口仅有一微导丝出口,经末端接口注入造影剂充盈扩张多个串珠样排列的球囊,压附在球囊上的管状交叉网丝3和滤器2随之顺势扩张, 血栓被挤碎并进入管状交叉网线3和滤器2内的球囊之间的空隙,使碎血栓位于管状交叉网线和滤器内。 Refer to FIG. 5, a multi-balloon catheter distal end portion 7 of a flexible and having a certain tension, the flexible distal end than the proximal part of the difference, the soft part of the distal end of the catheter having 3-5 beaded balloon arrangement, a single length of the balloon 5. 0-10. Omm, having a diameter of 2-5mm, balloon interval 5. 0-10. Omm ,, the flexible distal end portion of the sidewall a distance from the distal end (5-30cm) a micro guidewire aperture 8, through the holes in the guide wire lumen as well portion, wherein a cavity through the micro-guidewire, and the other chamber with the catheter tip balloon and various communication and terminating at a distal balloon, such that a distal port only micro guidewire outlet end by injecting the contrast agent filling the interface expandable balloon arranged in a plurality of beaded, cross is pressed against the tubular mesh 3 and the balloon on the filter 2 will take advantage of the expansion, thrombus be crushed and the crossover cable into the tubular balloon 3 and a space between the filter 2 in the thrombus located within the tubular broken lines and crossover filters.

请参阅图6,多球囊导管7也可以为单腔导管,导管远端出口8变细,仅能通过导丝l 前段细软部分,后面较粗部分直径大于出口直径,被变细的出口卡住,单腔导管末端的导管柄设有主孔和侧孔ll,侧孔末端可接三通,主孔末端内腔为漏斗型,内置一与之相匹配的带中央孔10的漏斗状橡皮圈8,末端套上带中央孔螺帽9。 Refer to FIG. 6, 7 multi-balloon catheter may be tapered outlet 8 as a single lumen catheter, the distal end of the catheter, the guidewire only through soft l anterior portion, thicker rear portion diameter greater than the outlet diameter, the tapered outlet card live, catheter handle single lumen catheter tip side hole and the main bore provided ll, tee can end side hole, the end of the main lumen is funnel-shaped hole, built with a central hole matches with a funnel-shaped rubber 10 ring 8, the end cap sleeve with a central bore 9. 导丝可以通过有中央孔10的螺帽9 和橡皮圈8,拧紧螺帽9的同时可以向主孔内腔挤压橡皮圈8,縮小或关闭中央孔IO,以固定和控制导丝l,并封闭球囊导管两端,然后经侧孔ll注入造影剂来充盈扩张多个串珠样排列的球囊,压附在球囊上的管状交叉网丝3和滤器2随之顺势扩张,血栓被挤碎并进入管状交叉网线3和滤器2内的球囊之间的空隙,使碎血栓位于管状交叉网线和滤器内。 Guidewire through the central hole 10 with a nut 9 and a rubber band 8, while tightening the nut 9 can be pressed into the main bore chamber 8 rubber band, narrow or close the IO central hole, to secure and control the guide wire L, closing both ends of the balloon catheter and then through the side hole injecting a contrast agent to filling ll expandable balloon arranged in a plurality of beaded, cross is pressed against the tubular mesh 3 and the balloon on the filter 2 will take advantage of the expansion, thrombus crushing and into the gap between the balloon and the tubular crossover cable 3 within the filter 2, so that thrombus located within the broken lines and the tubular crossover filter.

球囊导管及球囊是医用高分子塑料材料制成,比如聚乙烯、聚氯乙烯、聚氨酯、含氟树脂、聚丙烯等材料, Balloon catheter and the balloon are made of medical polymer plastic material such as polyethylene, polyvinyl chloride, polyurethane, fluorine resin, polypropylene or the like materials,

根据本发明,能够实施一种治疗由于脑血管血栓形成或栓子脱落栓塞脑血管的急性缺血性脑梗塞的方法: According to the present invention, since the method of cerebrovascular thrombosis or emboli shed acute ischemic infarction cerebrovascular thrombosis capable of implementing a method of treating:

采用Seldinger技术经股动脉或其他动脉血管插管,将外壳导管12推进到颈内动脉或椎动脉或其他部位的堵塞血管,进行血管造影,判断血栓阻塞情况,并将外壳导管靠近血栓部位,再经外壳导管将导丝1送入血管并穿过血栓到达血栓远端足够远的部位并固定,再将压附有管状交叉网丝3和滤器2的多球囊导管7沿导丝跟进并穿过血栓到达血栓远端,充盈多个球囊6以扩张管状交叉网丝3和滤器2,血栓被挤碎进入管状交叉网线内的球囊之间的空隙,使碎血栓位于管状交叉网丝3和滤器2内,抽空球囊6,并回抽球囊导管7,余下碎血栓位于交叉网丝3和滤器2内,回抽与交叉网丝相连的牵引导丝5,同时推进外壳导管12,使交叉网丝3和滤器2内部剩余碎血栓被收进外壳导管取出,实施过治疗程中可能有少量血栓经交叉网丝和滤器的网眼漏到血管内,但此时漏出的碎小血栓已 Seldinger technique through the femoral or other artery cannula, catheter 12 is advanced into the housing internal carotid artery or occlude the vessel, or other parts of the vertebral artery, angiography, thrombotic occlusion is determined, the catheter housing and close to thrombus, and then housing via a catheter guide wire 1 into the blood vessel and the thrombus through the distal end of the thrombus reaches sufficiently far portion and fixed, then the pressure with the tubular crossover wire 3 and a multi-balloon catheter of the filter 7 along the guide wire 2 and follow-up thrombus reaches the thrombus through the distal end, the balloon 6 to a plurality of filling the expandable tubular cross mesh filters 2 and 3, the crush of the thrombus into the gap between the inner tubular balloon crossover cable, so that the tubular cross-pieces thrombosis mesh 3 and filter 2, evacuated balloon 6, and 7 Withdrawing the balloon catheter, the remaining thrombus at the intersection of broken mesh 3 and the inner filter 2, the cross-linked Withdrawing pull guide wire mesh 5, while advancing the catheter housing 12 the crossover wire 3 remaining inside the filter 2, and is incorporated into the housing pieces thrombus catheter removed, the treatment process may be implemented through a small amount of thrombus through the crossover wire mesh filter and leak into the blood vessel, but this time thrombus leaked Suixiao already 会引起颅内大血管的阻塞而导致严重后果,并且由于在实施治疗过程中,采用了小剂量药物溶栓和肝素化,它可以将碎小血栓溶解。 It can cause intracranial occlusion of large blood vessels and lead to serious consequences, and due to the implementation of the course of treatment, the use of low-dose heparin and thrombolytic drugs, it can be Suixiao thrombolysis. 经外壳导管远端端口注入造影剂造影,观察血栓清除及血管再通情况。 The distal end of catheter housing via contrast medium injection port, and observe the thrombus removal artery recanalization.

Claims (9)

1、一种用于粉碎和取出血栓的装置,它包括:导丝、管状交叉网丝、滤器、牵引装置、多球囊导管和外鞘导管;球囊导管的远端柔软部分呈串珠样排列有多个球囊,球囊导管远段柔软部分为双腔,其中一腔可通过导丝,另一腔与各球囊及导管末端相通;管状交叉网丝的远端与滤器相连接,管状交叉网丝近端与牵引装置相连接,管状交叉网丝和滤器被压缩套附在多球囊导管的远端部分并覆盖多个球囊,导丝轴向穿过多球囊导管,导丝、牵引装置和多球囊导管的近端部分可移动地套有外鞘导管。 A pulverizing apparatus and taken for thrombus, which comprises: a guidewire, the tubular cross-mesh, filter, traction devices, multi-balloon catheter and outer sheath of the catheter; form the soft portion of the balloon catheter distal beaded arrangement soft part of the plurality of balloons, the balloon catheter is a dual lumen distal section, through which a guide wire lumen, the other end of each cavity and the balloon catheter in communication; the distal end of the tubular filter with a crossover wire is connected, the tubular cROSS mesh with the traction means is connected to the proximal end of the tubular filter crossover wire be compressed and attached to sleeve distal portion of a multi-balloon catheter and covers the balloon plurality of guide wire axially through the multi-balloon catheter, guidewire , a proximal portion and a plurality of traction means movably balloon catheter sleeve outer sheath of the catheter.
2、 所述如权利要求1所述的用于粉碎和取出血栓的装置,其特征在于管状交叉网丝由薄壁的金属管雕刻而成,或由多根螺旋状相互交叉的金属或纤维细丝或塑料网丝编织而成,远端与滤器相连,两者成为一个粉碎和捕获血栓的整体,近端与牵引装置相连。 2, the apparatus as claimed for crushing and extraction of the thrombus in claim 1, characterized in that the tubular cross mesh carved from a thin-walled metal tube, or a plurality of spirally interdigitated metal fibers or fine wire or plastic braided mesh, is connected to the distal end of the filter, both a crushing and integral capture thrombus proximal end connected to the traction means.
3、所述如权利要求1或2所述的用于粉碎和取出血栓的装置,其特征在于,滤器分为两部分,近段部分为管状,末端为漏斗状,管状交叉网丝和滤器网眼为菱形或便于压縮的多边形,滤器为更密集的交叉网丝组成,滤器的网眼小于管状交叉网丝的网眼,滤器部分网眼短对角线为100-500微米,长对角线为500-3000微米,管状交叉网丝的网眼较大, 长对角线为1000-5000微米,短对角线为500-3000微米。 3, as defined in claim 1 or claim pulverization and extraction means for thrombus, characterized in that the filter is divided into two portions, the proximal portion is tubular, a funnel-shaped end, and a tubular filter mesh wire crossover rhombic or polygonal facilitate compression, a more dense filter crossover filaments, tubular filter mesh smaller than a mesh of intersecting mesh, a mesh filter section short diagonal 100-500 microns, the long diagonal of 500 3000 microns, the crossover wire mesh tubular large diagonal length 1,000 to 5,000 microns, 500 to 3000 microns shorter diagonal.
4、 如权利要求1所述的用于粉碎和取出血栓的装置,其特征在于,滤器分为两部分, 近段部分为管状,末端为漏斗状,由多根轴对称结构的金属丝构成骨架,骨架外面套有薄膜,该薄膜上设有众多小孔,该小孔的直径为100至500微米,它可以既能让血液通过, 又可以阻止血栓或脱落的粥样斑块通过。 4, and pulverizing apparatus as claimed in claim withdrawn for thrombus claim 1, wherein the filter is divided into two portions, the proximal portion of the tubular end is funnel-shaped, axial symmetry by a plurality of wires constituting the backbone , sets out the skeleton with a film, the film is provided with many small holes, the aperture diameter of 100 to 500 microns, which can not only allow blood to pass, but also to prevent thrombus or plaque by falling.
5、 如权利要求l所述的用于粉碎和取出血栓的装置,其特征在于,所述的牵引装置为与管状交叉网丝的近端相连接的多根轴对称结构的细金属丝和牵引导丝,该牵引导丝与多球囊导管平行。 5, and pulverizing apparatus as claimed withdrawn for thrombus in claim l, wherein a plurality of fine metal wires of the axial symmetry of the traction means to the proximal end of the tubular mesh of intersecting and connected to the retractor guide wire, the guide wire and the pull parallel multi-balloon catheter.
6、 如权利要求1所述的用于粉碎和取出血栓的装置,其特征在于,所述的多球囊导管由远端含3-5个串珠样排列的球囊的柔软部分和具有一定张力的、柔性较远端差的近端部分组成,单个球囊长度为5. 0-10. Omm,直径为2-5mm,球囊间隔为5. 0-10. Omm。 Soft part 6, and pulverizing apparatus as claimed in claim withdrawn for thrombus claim 1, wherein the multi-balloon catheter arranged beaded 3-5 balloon having a distal end and containing a certain tension the flexible proximal portion than the distal poor composition, of a single length of the balloon 5. 0-10. Omm, 2-5 mm in diameter, the balloon interval 5. 0-10. Omm.
7、 如权利要求l所述的用于粉碎和取出血栓的装置,其特征在于,所述的多球囊导管远端柔性导管侧壁距远端20-50cm处有一微导丝通过孔,导丝通过孔远端部分为双腔, 其中一腔可通过微导丝,另一腔与和微导管末端及各球囊相通并终止于远侧球囊,使得远端口仅有一微导丝出口。 7, and pulverizing apparatus as claimed withdrawn for thrombus in claim l, wherein the multi-balloon catheter from the distal end of the flexible side wall of the catheter at a distal end of 20-50cm micro guidewire aperture, the guide wire through the lumen of the distal portion of the hole, wherein a guide wire lumen through the micro, and the other chamber with micro-balloon catheter tip and each communicating and terminating at a distal balloon, such that the port is just a micro guidewire distal outlet.
8、 如权利要求1所述的用于粉碎和取出血栓的装置,其特征在于,多球囊导管可以为单腔导管,导管远端出口变细,仅能通过导丝前段细软部分,后面较粗部分直径大于出口直径,被变细的出口卡住,单腔导管末端的导管柄设有主孔和侧孔,侧孔末端可接三通,主孔末端内腔为漏斗型,内置一与之相匹配的带中央孔的漏斗状橡皮圈,末端套上带中央孔螺帽。 8, and pulverizing apparatus as claimed in claim withdrawn for thrombus claim 1, wherein the multi-balloon catheter can be a catheter, the distal end of the catheter is a single lumen narrowing outlet, soft guidewire portion only through the pre-stage, later than an outlet portion diameter greater than the diameter of the coarse, stuck tapered outlet catheter handle single lumen catheter tip side hole and the main bore is provided, tee can end side hole, the end of the main lumen is funnel-shaped hole, and a built-in the funnel-shaped to match the rubber band with a central bore, the end cap sleeve with a central bore. 导丝可以通过有中央孔的螺帽和橡皮圈,拧紧螺帽的同时可以向主孔内腔挤压橡皮圈,縮小或关闭中央孔,以固定和控制导丝,并封闭球囊导管两端。 Guidewire may have a central aperture through the rubber band and a nut, the nut while tightening the rubber band can be pressed into the main chamber hole, reduced or closed central hole, to secure and control the guidewire and the balloon catheter is closed at both ends .
9、如权利要求l所述的用于粉碎和取出血栓的装置,其特征在于,所述外壳导管为薄壁大内腔的导管。 9, such crushing and extraction apparatus for thrombus claim l, wherein said conduit housing is a thin, large-lumen catheter.
CN 200610123099 2006-10-31 2006-10-31 Device for crushing and taking out thrombus CN101172051A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200610123099 CN101172051A (en) 2006-10-31 2006-10-31 Device for crushing and taking out thrombus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200610123099 CN101172051A (en) 2006-10-31 2006-10-31 Device for crushing and taking out thrombus

Publications (1)

Publication Number Publication Date
CN101172051A true CN101172051A (en) 2008-05-07

Family

ID=39420963

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200610123099 CN101172051A (en) 2006-10-31 2006-10-31 Device for crushing and taking out thrombus

Country Status (1)

Country Link
CN (1) CN101172051A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102068749A (en) * 2011-01-07 2011-05-25 上海硕创生物医药科技有限公司 Novel muti-segment balloon dilatation catheter
CN102090909A (en) * 2011-02-25 2011-06-15 李玉江 Anorectal postoperative analgesic and hemostatic device
CN102316809A (en) * 2009-02-20 2012-01-11 维尔返有限公司 Instrument for capturing thrombus in blood vessel
CN103212148A (en) * 2013-04-25 2013-07-24 何凡 Iliofemoral deep venous thrombosis moniliform eccentric sacculus thrombolysis thrombectomy catheter and using method of same
CN103566459A (en) * 2013-10-09 2014-02-12 周少飞 Anti-jamming balloon catheter
CN105726088A (en) * 2016-04-27 2016-07-06 湖南瑞康通科技发展有限公司 Thrombus removing device
CN106264661A (en) * 2016-08-25 2017-01-04 苗立夫 Intravascular catching device
CN106491181A (en) * 2017-01-16 2017-03-15 郑州大学第附属医院 Thrombus fetching device with multi-spiral structure
CN107198554A (en) * 2016-09-23 2017-09-26 赛诺医疗科学技术有限公司 Thrombus extraction apparatus

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102316809A (en) * 2009-02-20 2012-01-11 维尔返有限公司 Instrument for capturing thrombus in blood vessel
CN102068749A (en) * 2011-01-07 2011-05-25 上海硕创生物医药科技有限公司 Novel muti-segment balloon dilatation catheter
CN102090909A (en) * 2011-02-25 2011-06-15 李玉江 Anorectal postoperative analgesic and hemostatic device
CN103212148A (en) * 2013-04-25 2013-07-24 何凡 Iliofemoral deep venous thrombosis moniliform eccentric sacculus thrombolysis thrombectomy catheter and using method of same
CN103212148B (en) * 2013-04-25 2015-08-12 何凡 Iliofemoral deep venous thrombosis beaded eccentric balloon catheter dissolved thrombectomy
CN103566459A (en) * 2013-10-09 2014-02-12 周少飞 Anti-jamming balloon catheter
CN105726088A (en) * 2016-04-27 2016-07-06 湖南瑞康通科技发展有限公司 Thrombus removing device
CN106264661A (en) * 2016-08-25 2017-01-04 苗立夫 Intravascular catching device
CN107198554A (en) * 2016-09-23 2017-09-26 赛诺医疗科学技术有限公司 Thrombus extraction apparatus
CN106491181A (en) * 2017-01-16 2017-03-15 郑州大学第附属医院 Thrombus fetching device with multi-spiral structure

Similar Documents

Publication Publication Date Title
US8585713B2 (en) Expandable tip assembly for thrombus management
US10413310B2 (en) Restoring blood flow and clot removal during acute ischemic stroke
ES2304808T3 (en) Embolectomy catheters to treat stroke and other thromboembolic disorders in small vessels.
US6027487A (en) Low profile infusion catheter
US6514273B1 (en) Device for removal of thrombus through physiological adhesion
US6849068B1 (en) Aspiration catheter
JP2986500B2 (en) Vascular catheter
US8945161B2 (en) Device for opening occluded blood vessels
US7316678B2 (en) Catheter with associated extension lumen
US5895398A (en) Method of using a clot capture coil
US6508782B1 (en) Thrombolysis device
US6761727B1 (en) Filter assembly
JP2012183366A (en) Blood flow restoration and thrombus management
US20180206865A1 (en) Retrieval systems and methods for use thereof
US6458139B1 (en) Filter/emboli extractor for use in variable sized blood vessels
JP2012501682A (en) Articulating extraction device
US20030055398A1 (en) Methods for reducing distal embolization
US6936025B1 (en) Thrombolysis device
JP6374577B2 (en) Recovery system and method of use
US20100262124A1 (en) Spiral balloon catheter
EP1210142B1 (en) Apparatus for reducing embolization during treatment of carotid artery disease
EP1496972B1 (en) Apparatus with infusion catheter having an atraumatic tip
JP4247111B2 (en) Apparatus and method for aspirating emboli
US20060200191A1 (en) Method and apparatuses for treating an intravascular occlusion
US8568465B2 (en) Device for rechanneling a cavity, organ path or vessel

Legal Events

Date Code Title Description
C06 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)