CN101168005A - Medicinal composition for treating vaginal dryness, sexual intercourse difficulty, dysmenorrhoea and leukorrhea - Google Patents

Medicinal composition for treating vaginal dryness, sexual intercourse difficulty, dysmenorrhoea and leukorrhea Download PDF

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Publication number
CN101168005A
CN101168005A CNA2007101769001A CN200710176900A CN101168005A CN 101168005 A CN101168005 A CN 101168005A CN A2007101769001 A CNA2007101769001 A CN A2007101769001A CN 200710176900 A CN200710176900 A CN 200710176900A CN 101168005 A CN101168005 A CN 101168005A
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China
Prior art keywords
parts
fructus
rhizoma
dyspareunia
flos carthami
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CNA2007101769001A
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Chinese (zh)
Inventor
鄢良
张韬
张云峰
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BEIJING ZHONGKE YONGHE MEDICAL TECHNOLOGY Co Ltd
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BEIJING ZHONGKE YONGHE MEDICAL TECHNOLOGY Co Ltd
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Priority to CNA2007101769001A priority Critical patent/CN101168005A/en
Publication of CN101168005A publication Critical patent/CN101168005A/en
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Abstract

The invention discloses a medicament composition for curing over-dried vagina, dyspareunia, dysmenorrheal and leucorrhea diseases. The medicine composition is mainly composed of raw medicines according to the part by weight, such as camellia oil 400 parts, cinnamomum cassia, evodia rutaecarpa and rhizoma zedoariae which are respectively 200 parts, cnidium fruit, safflower and curculigo rhizome which are separately 150 parts and pricklyash peel 50 parts. The medicine composition of the invention is capable of warming yang, dispersing cold, promoting blood circulation, freeing channel, smoothing and relieving itch and is adaptable for women with over-dried vagina, cold womb, hyposexuality and dyspareunia. Furthermore, the invention can be used to cure female diseases caused by asthenia-cold of kidney and liver, such as dull pain of the lower abdomen, irregular menstruation, dysmenorrheal and leucorrhea diseases, and treat impotence of men. The invention is simple in dispensation and easy in production. The medicine composition of the invention employs pure Chinese herbal medicine to produce and has the advantages of obvious curing effect, little toxic and side effects and convenient utilization, thereby having wide application value.

Description

A kind of pharmaceutical composition for the treatment of vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia
Technical field the present invention relates to a kind of pharmaceutical composition for the treatment of vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia, belongs to warming YANG to expel cold, promoting blood circulation to remove obstruction in the collateral and lubricated antipruritic etc. technical field of pharmaceuticals.Be used for dry and astringent, the sombre cold womb of woman vagina, hyposexuality and dyspareunia, can be used for treating the women and due to the Liver and kidney deficiency and coldness, lack disease and impotence in male such as abdomen cold type of pain, menoxenia, dysmenorrhea and leukorrhagia.
Background technology colpoxerosis, vaginitis and acute and chronic cervicitis are women's common frdquently encountered diseases, colpoxerosis is because the vaginal lubrication difference causes, growth along with female age, ovarian function is faded, decrease in estrogen, secretion capacity descends thereupon, cause woman vagina dry and astringent gradually, follow the string and sombre cold womb, cause libido to descend and dyspareunia, intensification along with this situation, also can cause gynaecopathia such as vaginitis, acute and chronic cervicitis, menoxenia, dysmenorrhea and leukorrhagia, bring very big misery to patient.And the method for treatment vaginal dryness commonly used is to use vaginal lubricant at present, its composition mostly is glycerol, vaseline, paraffin oil, estrogen and vitamin etc., lack excellent lubricating properties, can not reach the purpose of effecting a permanent cure, life-time service is estrogenic also can to produce some side effect simultaneously.Therefore also not with effect of the present invention quite, the treatment vaginal dryness for the treatment of both the principal and secondary aspects of a disease and the pure Chinese medicinal preparation of dyspareunia.
The purpose of this invention is to provide a kind of Chinese medicine for outer use for the treatment of vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia.We have better curative effect to vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia, can play good lubricated and moistening effect to vagina, to the nontoxic nonirritant of vaginal mucosa, short treating period, cure rate height.The present invention be directed to this sick pathogeny and Therapeutic Principle, in conjunction with the modern Chinese medicine theory, warming YANG to expel cold, promoting blood circulation to remove obstruction in the collateral, it is lubricated to dispel the wind, killing parasites for relieving itching.Select the pure natural Chinese herbal medicine for use, adopt the conventional method of Chinese medicine preparation to be mixed with external-use oil preparation, easy to use.
Summary of the invention the object of the present invention is to provide a kind of pharmaceutical composition of evident in efficacy, easy to use, diseases such as treatment vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia that side effect is little.
The present invention also provides this preparation of drug combination method.
Pharmaceutical composition of the present invention can be used for treating dry and astringent, the sombre cold womb of woman vagina, hyposexuality and dyspareunia, can be used for treating the women and lack disease and impotence in male such as abdomen cold type of pain, menoxenia, dysmenorrhea and leukorrhagia due to the Liver and kidney deficiency and coldness.
Pharmaceutical composition of the present invention is prepared from by the following weight parts proportion raw material:
10~200 parts in 100~800 parts of Oleum Camelliae, 100~500 parts of Cortex Cinnamomis, 100~500 parts of Fructus Evodiaes, 100~500 parts of Rhizoma Curcumae, 100~400 parts of Fructus Cnidiis, 100~400 parts on Flos Carthami, 100~400 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
Pharmaceutical composition of the present invention is prepared from by following preferred weight part proportion raw material:
10~100 parts in 200~500 parts of Oleum Camelliae, 100~300 parts of Cortex Cinnamomis, 100~300 parts of Fructus Evodiaes, 100~300 parts of Rhizoma Curcumae, 100~250 parts of Fructus Cnidiis, 100~250 parts on Flos Carthami, 100~250 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
Pharmaceutical composition of the present invention is prepared from by following optimum weight part proportion raw material:
50 parts in 400 parts of Oleum Camelliae, 200 parts of Cortex Cinnamomis, 200 parts of Fructus Evodiaes, 200 parts of Rhizoma Curcumae, 150 parts of Fructus Cnidiis, 150 parts on Flos Carthami, 150 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
Pharmaceutical composition of the present invention can be prepared from by following method:
1, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii and the Pericarpium Zanthoxyli etc. with described weight portion add water saturates, and steam distillation extracts volatile oil;
2, Flos Carthami, the Rhizoma Curculiginis merging with medicinal residues and described weight portion decocts with water 2 times, and each 1 hour, filter the back and merge 2 filtrates, be concentrated into relative density 1.40;
3, the Oleum Camelliae that adds described weight portion stirred dipping 24 hours, 100 ℃ of insulations 5 hours, and room temperature is filtered the back and is added volatile oil and a small amount of essence, stirs, and filters promptly.
Prescription of the present invention is made up of seven flavor Chinese medicines such as Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii, Flos Carthami, Rhizoma Curculiginis and Pericarpium Zanthoxyli.
Modern pharmacological research shows: vagina mostly is deficiency of vital QI, evil poison is invaded in taking advantage of a weak point in opponent's defence, that damp is accumulate is long-pending, must not let out for a long time, accumulate humidogene heat, pyretic toxicity is unclear, and used Chinese medicine has activating blood circulation to dissipate blood stasis, eliminating evil dampness effect more in the side, also adds the medicine of understanding poisoning worm, anti-inflammatory anti-itch.Wherein Cortex Cinnamomi to mend fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation is used for the dysmenorrhea of cold coagulation stasis and amenorrhea etc.; The Fructus Evodiae dispersing cold for relieving pain, the soothing liver-QI sending down the abnormal ascending QI is used for supporing yang antidiarrheal, warming and recuperating the spleen and kidney; The circulation of qi promoting of Rhizoma Curcumae removing blood stasis, the removing food stagnancy pain relieving is used for amenorrhea due to the stagnation of QI and blood and trusted subordinate's twinge etc.; The Rhizoma Curculiginis warming the kidney to invigorate YANG, bone and muscle strengthening, dispelling cold and dampness, warming spleen and stopping diarrha, be used for menoxenia and climacteric hypertension, the card person that sees the deficiency of both YIN and YANG; The Flos Carthami promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing is used for dysmenorrhea due to blood stasis, amenorrhea etc.; Fructus Cnidii is cold to dispel the wind, and removing dampness and killing parasites is antipruritic, is used for the cold-damp leukorrhagia, pudendum pruritus due to damp pathogen, eczema, scabies etc.; The Pericarpium Zanthoxyli warming middle-JIAO to relieve pain, killing parasites for relieving itching is used for eczema pruritus, pudendal pruritus etc.; Above seven flavor medicine is used, and has played the effect of activating blood circulation to dissipate blood stasis, eliminating evil dampness, detoxifcation, killing parasites for relieving itching.Add medical Oleum Camelliae free from extraneous odour, easily absorption, non-greasy, health, it is rich in natural high-quality vitamin E, A, B, D, K, F etc., to the nourishing of intravaginal hymeniderm skin as mild as a dove, therefore diseases such as vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia had splendid therapeutic effect.
Pharmaceutical composition of the present invention shows through effect experiment, toxicological test and stability experiment, and is evident in efficacy, nontoxic, good stability, and the patient is easy to use.Treatment vaginal dryness patient case 324 examples, effective 300 examples, 24 examples that take a turn for the better, invalid uncomfortable case, total effective rate is 100%.Therefore be with a wide range of applications.
The specific embodiment
Embodiment 1
40 parts in 300 parts of Oleum Camelliae, 150 parts of Cortex Cinnamomis, 150 parts of Fructus Evodiaes, 150 parts of Rhizoma Curcumae, 100 parts of Fructus Cnidiis, 100 parts on Flos Carthami, 100 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii and the Pericarpium Zanthoxyli etc. of described weight portion are added water saturates, and steam distillation extracts volatile oil; Medicinal residues and Flos Carthami, Rhizoma Curculiginis merging decoct with water 2 times, and each 1 hour, filter the back and merge 2 filtrates, be concentrated into relative density 1.40, add Oleum Camelliae, stirred dipping 24 hours, 100 ℃ are incubated 5 hours, room temperature is filtered the back and is added volatile oil and a small amount of essence, stirs, and filters promptly.Using method: external is applied to clean affected part.
Embodiment 2
70 parts in 350 parts of Oleum Camelliae, 250 parts of Cortex Cinnamomis, 250 parts of Fructus Evodiaes, 250 parts of Rhizoma Curcumae, 200 parts of Fructus Cnidiis, 200 parts on Flos Carthami, 200 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii and the Pericarpium Zanthoxyli etc. of described weight portion are added water saturates, and steam distillation extracts volatile oil; Medicinal residues and Flos Carthami, Rhizoma Curculiginis merging decoct with water 2 times, and each 1 hour, filter the back and merge 2 filtrates, be concentrated into relative density 1.40, add Oleum Camelliae, stirred dipping 24 hours, 100 ℃ are incubated 5 hours, room temperature is filtered the back and is added volatile oil and a small amount of essence, stirs, and filters promptly.Using method: external is applied to clean affected part.
Embodiment 3
50 parts in 400 parts of Oleum Camelliae, 200 parts of Cortex Cinnamomis, 200 parts of Fructus Evodiaes, 200 parts of Rhizoma Curcumae, 150 parts of Fructus Cnidiis, 150 parts on Flos Carthami, 150 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii and the Pericarpium Zanthoxyli etc. of described weight portion are added water saturates, and steam distillation extracts volatile oil; Medicinal residues and Flos Carthami, Rhizoma Curculiginis merging decoct with water 2 times, and each 1 hour, filter the back and merge 2 filtrates, be concentrated into relative density 1.40, add Oleum Camelliae, stirred dipping 24 hours, 100 ℃ are incubated 5 hours, room temperature is filtered the back and is added volatile oil and a small amount of essence, stirs, and filters promptly.Using method: external is applied to clean affected part.

Claims (4)

1. pharmaceutical composition for the treatment of vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia is characterized in that the medicine material that raw material contains following weight portion proportioning forms: 10~200 parts in 100~800 parts of Oleum Camelliae, 100~500 parts of Cortex Cinnamomis, 100~500 parts of Fructus Evodiaes, 100~500 parts of Rhizoma Curcumae, 100~400 parts of Fructus Cnidiis, 100~400 parts on Flos Carthami, 100~400 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
2. require described pharmaceutical composition according to right 1, it is characterized in that the medicine material that raw material contains following weight portion proportioning forms: 10~100 parts in 200~500 parts of Oleum Camelliae, 100~300 parts of Cortex Cinnamomis, 100~300 parts of Fructus Evodiaes, 100~300 parts of Rhizoma Curcumae, 100~250 parts of Fructus Cnidiis, 100~250 parts on Flos Carthami, 100~250 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
3. require the pharmaceutical composition of described treatment vaginal dryness, dyspareunia, dysmenorrhea and leukorrhagia according to right 1,2, it is characterized in that the optimised quantity of each raw material is: 50 parts in 400 parts of Oleum Camelliae, 200 parts of Cortex Cinnamomis, 200 parts of Fructus Evodiaes, 200 parts of Rhizoma Curcumae, 150 parts of Fructus Cnidiis, 150 parts on Flos Carthami, 150 parts of Rhizoma Curculiginises and Pericarpium Zanthoxyli.
4. require described medicine according to right 3, Cortex Cinnamomi, Fructus Evodiae, Rhizoma Curcumae, Fructus Cnidii and the Pericarpium Zanthoxyli etc. of described weight portion are added water saturates, steam distillation extracts volatile oil; Medicinal residues and Flos Carthami, Rhizoma Curculiginis merging decoct with water 2 times, and each 1 hour, filter the back and merge 2 filtrates, be concentrated into relative density 1.40, add Oleum Camelliae, stirred dipping 24 hours, 100 ℃ are incubated 5 hours, room temperature is filtered the back and is added volatile oil and a small amount of essence, stirs, and filters promptly.
CNA2007101769001A 2007-11-07 2007-11-07 Medicinal composition for treating vaginal dryness, sexual intercourse difficulty, dysmenorrhoea and leukorrhea Pending CN101168005A (en)

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CNA2007101769001A CN101168005A (en) 2007-11-07 2007-11-07 Medicinal composition for treating vaginal dryness, sexual intercourse difficulty, dysmenorrhoea and leukorrhea

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102138955A (en) * 2011-03-16 2011-08-03 李德伟 Sexual intercourse lubricant
CN104547277A (en) * 2015-01-06 2015-04-29 张金辉 Navel plaster
CN105535737A (en) * 2016-01-22 2016-05-04 黄丹耒 Traditional Chinese medicine preparation externally applied or orally taken for treating women dysmenorrheal and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102138955A (en) * 2011-03-16 2011-08-03 李德伟 Sexual intercourse lubricant
CN104547277A (en) * 2015-01-06 2015-04-29 张金辉 Navel plaster
CN105535737A (en) * 2016-01-22 2016-05-04 黄丹耒 Traditional Chinese medicine preparation externally applied or orally taken for treating women dysmenorrheal and preparation method thereof

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Open date: 20080430