CN101161276A - Nebula pressurized spray for treating rehabilitation of exogenous injury, empyrosis and bone fracture as well as its preparing method - Google Patents
Nebula pressurized spray for treating rehabilitation of exogenous injury, empyrosis and bone fracture as well as its preparing method Download PDFInfo
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- CN101161276A CN101161276A CNA2006101136038A CN200610113603A CN101161276A CN 101161276 A CN101161276 A CN 101161276A CN A2006101136038 A CNA2006101136038 A CN A2006101136038A CN 200610113603 A CN200610113603 A CN 200610113603A CN 101161276 A CN101161276 A CN 101161276A
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- scald
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Abstract
The present invention relates to a spraying agent for treating injury, burn and scald, and bone injury recovery, belonging to external-applied traditional Chinese medicine preparation. It is composed of borneol, toad venom, vermilion, rhubarb, muskiness, dragon's blood six Chinese herbs, its manufacturing method is: mixing and grinding the six Chinese herbs according to proportion; sieving the fine powder with 100 mesh sieve; mixing the sieved fine powder and 95 percent ethanol according to 1: 2 to 7; every day using ultrasonic vibrating the mixed liquid 10 to 30 minutes (normal pressure) and mixing uniformly, time is 1 to 21 days; filtering the mixed uniformly medicine liquid; the filter liquid adding water to dilute to ethanol concentration is 55 to 75 percent; standing, filling, sealing and finishing products. The present invention has advantages of cooling blood and eliminating toxins, relaxing muscles and joints, quick effective and long effective, relieving pain and detumescence, promoting hematoma absorption, antibiotic and diminishing inflammation, preventing injury infection, wound surface rapid scabbing, after treatment without scar. It has better curative effect for activating bone cell, bone recovery, burn and scald.
Description
Technical field
The present invention relates to a kind ofly treat wound, burn and scald and bone injury is had spray of rehabilitative action and preparation method thereof, belong to Chinese medicine for outer use.
Background technology
Institutes such as various wounds, burn and scald, bone injury require the onset of the efficacy of a drug rapid, and efficiency time is long, and comprehensive more multi-faceted allomeric function is strong.Existing be used for wound, blood circulation promoting and blood stasis dispelling, alleviating pain and detumescence is although the Chinese patent medicine of dispelling wind and removing obstruction in the collateral and prescription are a lot, but be mostly that effect is more single, allomeric function is renderd a service not enough, and the cicatrix repairing effect that externally recovers from injury after closing is not ideal enough, is still waiting further research, exploitation and raising at present.
Summary of the invention
The object of the present invention is to provide a kind of treatment wound, small size skin burn, bone wound recovering, multi-faceted spray that strong effect is all arranged and preparation method thereof.It is to combine with Chinese herbal medicine is ingenious so that differential diagnosis in tcm is theoretical, the length of the existing treatment of development based on inheritance traumatic injury Chinese medicine, and innovation research goes out to be mainly used in wound, bone injury, soft tissue contusion, antiphlogistic and bactericidal, recovery skin is seamless, and quick-acting antalgesic is renderd a service persistent new prescription.Small size burn and scald, bone injury are all had certain alleviation misery, incrustation fast, the effect of repairing cicatrix, usage is simple, and effect duration is long, and function is polynary, and comprehensive effectiveness is strong.Be closely related with life, it is medicinal to can be used as standing first aid.
The objective of the invention is to be realized that by following technical scheme it is formed by Borneolum Syntheticum, Venenum Bufonis, Cinnabaris, Radix Et Rhizoma Rhei, Moschus, dragon's blood six prepared from traditional Chinese medicines, the weight proportion of each component is:
Borneolum Syntheticum 20-40g
Venenum Bufonis 10-30g
Cinnabaris 20-50g
Radix Et Rhizoma Rhei 30-50g
Moschus 1-4g
Sanguis Draxonis 2-5g
Its manufacture method may further comprise the steps:
1,, the Six-element Chinese herbal medicine mixed and is ground into fine powder by said ratio;
2, with 100 mesh sieve fine powder is sieved;
3, the fine powder after will sieving and 95% ethanol are by 1: the 2-7 proportioning is mixed;
4, above-mentioned mixed liquor is adopted 10-30 minute (under the normal pressure) mixing of excusing from death ripple vibration every day, the time is 1-21 days;
5, with the medical filtration behind the mixing;
6, filtrate thin up to concentration of alcohol is 55-75%;
7, leave standstill, fill is sealed, and goes out finished product.
Advantage of the present invention is: this spray medicinal liquid is the mutual compatibility of selected Chinese herbal medicine, assist a ruler in governing a country mutually, topical agent with the modern means of science and technology infusion, be that theory of Chinese medical science is reached removing pathogenic heat from blood and toxic substance from the body, soothing the channels and quicking the network vessels, quick-acting long-acting, alleviating pain and detumescence with ingenious combination of herbal function, promote absorption of hematoma, the effect of anti-inflammation all has in various degree inhibitory action to the various skin fungus.The prevention trauma infection contamination is hindered face and is formed a scab fast, more after trace not.To activating osteocyte, rehabilitation bone, burn have better curative effect.
Medical liquid container of the present invention adopts the hand spray bottle, considers that spray bottle is commonly used in pharmacy industry, and cheap, and the dissolve with ethanol drug level is better, and advantages such as free from extraneous odour are so select the spray dosage form.The spray dosage form has absorption rapidly, and it is fast to prove effective, and convenient, preservation is easy to carry.
Spray practicality of the present invention is extremely strong, can be family, social unit etc., standing first aid medication.Specification can be selected according to purposes from 10-500ml.
One, inventive principle:
Spray medicinal liquid of the present invention is to form with multiple Chinese herbal medicine refine infusion, with blood circulation promoting and blood stasis dispelling, the collateral dredging bone strengthening is main, with regulate the flow of vital energy, the spleen invigorating hemopoietic, mend marrow be attached, be equipped with regulate the flow of vital energy, benefit essence, removing blood stasis, gradually to improve local blood circulation, detumescence, pain relieving, bone growth promoting, to reach the purpose of promoting blood circulation, removing blood stasis and relieving pain bone growth promoting.
Differential diagnosis in tcm is executed and is controlled to mend, rush down, cold, heat, gas, blood is made into prescription for this choosing with smart medicine, the present invention is a topical agent, by concentrating on studies for many years, summing up experience, with theory of Chinese medical science and herbal function is ingenious combines, select the essence, abandon its dross, efficient to reach, utilize the property of medicine of medicine, reach cooling blood for hemostasis to purify the blood branch heat, regulating qi and activating blood and separate the stasis of blood, wind-expelling pain-stopping and bone and muscle strengthening, eliminating dampness and diuresis and subsiding a swelling, enriching blood and replenishing vital essence and give birth to marrow, dispersing pathogen accumulation and effects such as the poison of dispelling, form removing heat from blood and promoting blood circulation, detumescence, antiinflammatory, bone growth promoting fully proves this side's effect by clinic trial.
Spray prescription of the present invention is a topical agent, and clinical spray applications is used for the treatment of the swelling and pain due to blood stasis due to the traumatic injury for many years, and we have blood circulation promoting and blood stasis dispelling, the repercussive analgesic effect, and curative effect is preferable.Be total to 83-179 gram crude drug in the side, through with ethanol with 1: the 2-7 proportioning process extracts medicinal liquid trial-production and experimental results show that: improved the Chinese traditional medicine biology availability, is provided action time that can be scheduled to, long, reduced drug toxicity and side effect, reduced the decomposition and the waving of volatile ingredient of middle pharmaceutically active ingredient and separated.Select the spray dosage form, thereby guarantee the curative effect of medicine.
Two, pharmacological effect:
(1) Radix Et Rhizoma Rhei: have purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the merit of eliminating blood stasis and inducing menstruation.
(2) Borneolum Syntheticum: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
(3) Venenum Bufonis: have detoxifcation, pain relieving, the refreshment effect of having one's ideas straightened out.
(4) Moschus: the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.
(5) Cinnabaris: it is relieving convulsion to clear away heart-fire, the detoxifcation of calming the nerves.
(6) Sanguis Draxonis: removing blood stasis and relieving pain, hemostasia and promoting granulation.
Three, using method:
1, blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, reducing swelling and alleviating pain; Be used for traumatic injury, swelling and pain due to blood stasis, the resistance of the rheumatism stasis of blood, arthralgia.The spraying affected part is massaged 5～10 minutes to affected part heating, 2～3 times on the one; Soft tissue sprain is serious or the bleeder is arranged, and the cotton pad that medicinal liquid is squirted spreads on the affected part.
2, soft tissue injury and non-open fracture are at injury spraying medicinal liquid of the present invention, spray one deck when spraying first earlier gently on the surface, sprayed once again behind the pharmaceutical drying every 1-2 minute approximately, 3 to 4 times repeatedly, promptly form one deck medicine film, promptly reach the pain relieving purpose after about 5-15 minute, spraying for the second time after about 1 hour, spraying in back 2-3 hour was once used 3 to 7 days altogether.
3, open injury can spray medicine earlier around as there not being tangible massive hemorrhage, and to reach the pain relieving purpose, postoperative can continue to use this medicine.
The specific embodiment
Embodiment 1:
The spray of the described treatment wound of present embodiment, burn and scald, bone wound recovering, it is formed by Borneolum Syntheticum, Venenum Bufonis, Cinnabaris, Radix Et Rhizoma Rhei, Moschus, dragon's blood six prepared from traditional Chinese medicines, and the weight proportion of each component is: Borneolum Syntheticum 35g, Venenum Bufonis 25g, Cinnabaris 20g, Radix Et Rhizoma Rhei 30g, Moschus 2.5g, Sanguis Draxonis 5g;
Its manufacture method may further comprise the steps:
1,, the Six-element Chinese herbal medicine mixed and is ground into fine powder by said ratio;
2, with 100 mesh sieve fine powder is sieved;
3, the fine powder after will sieving and 95% ethanol are by 1: the 2-7 proportioning is mixed;
4, above-mentioned mixed liquor is adopted 10-30 minute (under the normal pressure) mixing of excusing from death ripple vibration every day, the time is 1-21 days;
5, with the medical filtration behind the mixing;
6, filtrate thin up to concentration of alcohol is 55-75%;
7, leave standstill, fill is sealed, and goes out finished product.
Embodiment 2:
The spray of the described treatment wound of present embodiment, burn and scald, bone wound recovering, the weight proportion of each component is: Borneolum Syntheticum 40g, Venenum Bufonis 10g, Cinnabaris 30g, Radix Et Rhizoma Rhei 45g, Moschus 4g, Sanguis Draxonis 2g;
Its manufacture method is with embodiment 1.
Embodiment 3:
The spray of the described treatment wound of present embodiment, burn and scald, bone wound recovering, the weight proportion of each component is: Borneolum Syntheticum 20g, Venenum Bufonis 30g, Cinnabaris 40g, Radix Et Rhizoma Rhei 50g, Moschus 1g, Sanguis Draxonis 3g;
Its manufacture method is with embodiment 1.
Embodiment 4:
The spray of the described treatment wound of present embodiment, burn and scald, bone wound recovering, the weight proportion of each component is: Borneolum Syntheticum 30g, Venenum Bufonis 20g, Cinnabaris 25g, Radix Et Rhizoma Rhei 35g, Moschus 3g, Sanguis Draxonis 2.5g;
Its manufacture method is with embodiment 1.
Embodiment 5:
The spray of the described treatment wound of present embodiment, burn and scald, bone wound recovering, the weight proportion of each component is: Borneolum Syntheticum 25g, Venenum Bufonis 35g, Cinnabaris 50g, Radix Et Rhizoma Rhei 40g, Moschus 2g, Sanguis Draxonis 4g;
Its manufacture method is with embodiment 1.
The clinical trial case:
One, data:
Male's 106 examples among the 157 routine patients, women's 51 examples, the age is at 3-82 between year, average 47 years old, soft tissue contusion's 21 examples wherein, Ke Lishi 36 examples of fracturing, forearm fracture 23 examples, humeral shaft fracture 14 examples, buttocks diaphyseal bone 9 examples of fracturing, fracture of tibia and fibula 29 examples, ankle joint fracture 14 examples, hands and sprain of foot 18 examples have 7 examples to be complex injury in these damages.
Two, clinical observation:
1. pain relieving:
157 routine patients have all received obvious analgesic effect, the soft tissue injury effect is the most obvious, 3-5 minute can take effect, extremity fracture can take effect about 10 minutes, upper limb and fracture of tibia and fibula, after the ankle joint fracture medication reduction and when moving the patient all can stand, pain obviously alleviates when carrying after the fracture of shaft of femur medication, under inactive situation, all can reach the pain relieving purpose after all patient's medications, comprise all other analgesic of reuse not of operation back patient, all can not fall asleep with tranquilizer evening yet, and medication back light activity does not one day after also have obvious pain, and pain disappears substantially after 3-5 days.
2. detumescence:
5 minutes is that visible swelling begins to disappear after the soft tissue injury medication, and wrinkle appears in skin, and visible swelling begins obviously to alleviate after 1 hour, and the swelling 30-50% that can disappear disappears after three hours substantially about 4-6 hour.Extremity fracture patient swelling in 3-7 days disappears substantially.
3. union of fracture
Spray medicinal liquid of the present invention, the X-ray film making is checked and is all shown obvious effects, during a week, forearm fracture 7 examples, proximal tibia 4 examples of fracturing, the totally 11 examples patients that do not have an obviously dislocation all have obvious callus, during two weeks, forearm fracture 18 examples, the proximal tibia 8 routine growth of spur of fracturing are obvious, upper arm diaphyseal bone 11 examples of fracturing, femoral shaft bone 3 examples of fracturing, hypomere 16 examples of fracturing also have obvious callus in the tibia, and film making checks that miscellaneous fracture all has a large amount of callus during 5 weeks, and the disunion situation does not take place.
4. the application of treatment burn
Invigorate blood circulation according to the present invention, the pharmacological action of pain relieving, detumescence, antiinflammatory, we try out the patient of 3 routine shallow II degree burn and scald, received the obvious treatment effect, wherein 1 routine scalding area has reached 70%, all there is scald at breast, waist, back, receive analgesic effect at once behind spraying the present invention, it is dry partly to hop to it after half an hour, per hour spray once, the state of an illness has been controlled in the partly substantially dry incrustation of shallow II degree after 12 hours, the partly all healings of the shallow II degree in one week back, 2 routine areas are less in addition, all reached pain relieving immediately, the purpose of week recovery from illness.
5. general little wound, as knock against hard, bump brokenly, scratch hemorrhage etc., even if a lot of fouls are arranged on the wound, also need not sterilization, directly spray, both can kill pathogenic bacterium fast, can stop blooding the very fast healing of wound, not easy infection again.
Claims (2)
1. spray for the treatment of wound, burn and scald, bone wound recovering, it is characterized in that: it is formed by Borneolum Syntheticum, Venenum Bufonis, Cinnabaris, Radix Et Rhizoma Rhei, Moschus, dragon's blood six prepared from traditional Chinese medicines, and the weight proportion of each component is:
Borneolum Syntheticum 20-40g
Venenum Bufonis 10-30g
Cinnabaris 20-50g
Radix Et Rhizoma Rhei 30-50g
Moschus 1-4g
Sanguis Draxonis 2-5g
2. the manufacture method of the spray of treatment wound as claimed in claim 1, burn and scald, bone wound recovering is characterized in that: may further comprise the steps:
1. by said ratio, the Six-element Chinese herbal medicine mixed and be ground into fine powder;
2. with 100 mesh sieve fine powder is sieved;
3. the fine powder after will sieving and 95% ethanol are by 1: the 2-7 proportioning is mixed;
4. above-mentioned mixed liquor is adopted 10-30 minute mixing of excusing from death ripple vibration every day, the time is 1-21 days;
5. with the medical filtration behind the mixing;
6. filtrate thin up to concentration of alcohol is 55-75%;
7. leave standstill, fill is sealed, and goes out finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610113603A CN101161276B (en) | 2006-10-09 | 2006-10-09 | Spray for treating exogenous injury, empyrosis and bone fracture as well as its preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610113603A CN101161276B (en) | 2006-10-09 | 2006-10-09 | Spray for treating exogenous injury, empyrosis and bone fracture as well as its preparing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101161276A true CN101161276A (en) | 2008-04-16 |
| CN101161276B CN101161276B (en) | 2010-05-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200610113603A Expired - Fee Related CN101161276B (en) | 2006-10-09 | 2006-10-09 | Spray for treating exogenous injury, empyrosis and bone fracture as well as its preparing method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341036A (en) * | 2013-07-11 | 2013-10-09 | 徐计锁 | External medicine for treating burn |
| CN104547825A (en) * | 2014-12-29 | 2015-04-29 | 孙丰卿 | Traditional Chinese medicine composition for treating neuromuscular pain and preparation method of preparation of traditional Chinese medicine composition |
| CN107126542A (en) * | 2017-05-23 | 2017-09-05 | 汪建军 | A kind of bone fracture spray and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1795909A (en) * | 2004-12-22 | 2006-07-05 | 北京国药苑科技有限公司 | 'Qili' preparationfor treating injuries from falls and production method |
-
2006
- 2006-10-09 CN CN200610113603A patent/CN101161276B/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341036A (en) * | 2013-07-11 | 2013-10-09 | 徐计锁 | External medicine for treating burn |
| CN104547825A (en) * | 2014-12-29 | 2015-04-29 | 孙丰卿 | Traditional Chinese medicine composition for treating neuromuscular pain and preparation method of preparation of traditional Chinese medicine composition |
| CN104547825B (en) * | 2014-12-29 | 2018-03-30 | 青岛大学附属医院 | A kind of preparation method for the Chinese medicine composition and its preparation for treating myoneural pain |
| CN107126542A (en) * | 2017-05-23 | 2017-09-05 | 汪建军 | A kind of bone fracture spray and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN101161276B (en) | 2010-05-12 |
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Granted publication date: 20100512 Termination date: 20211009 |