CN101085077A - 'Tongpiluo' capsule - Google Patents

Abstract

The invention discloses a capsule for relaxing vein which is prepared from the following medicinal herbs (by weight ratio): radix rubiae root 1 part, spatholobus stem 1 parts, buffalo horn 2 parts, herba patriniae 3 parts, buthus martensi kirsch 1/2 part, black-tail snake 1/3 part, agkistrodon acutus 1/2 part, licorice 1/10 part. And the preparing process comprises the steps of mixing radix rubiae root, spatholobus stem, herba patriniae, licorice root, grilling twice, filtering the extract, mixing and concentrating into medicinal soup, disintegrating Garter snake, buthus martensi karsch, agkistrodon acutus, buffalo horn as matrix, mixing with concentration liquid and homogenizing, drying, and loading into capsules.

Description

'Tongpiluo ' capsule

Technical field

The application belongs to Chinese medicinal capsule, especially treats psoriatic Chinese medicinal capsule.

Background technology

Psoriasis, the traditional Chinese medical science claim white Mange, are commonly called as psoriasis, are a kind of dermatosiss of obstinate refractory, the Chang Fanfu outbreak.Many doctor families and scholar inquire into and study its pathomechanism and treatment, are obtaining certain achievement aspect clinical and the test, but are not making a breakthrough as yet generally.Doctor trained in Western medicine is not clear fully to its pathogenic factor, and adopt mostly in the treatment and suppress the splitted medicine of epidermis cell, as immune formulation, the external hormone medicine, this type of medicine side reaction is many, and easily recurrence forms vicious cycle after the drug withdrawal.The traditional Chinese medical herbal treatment primary disease is controlled through dialectical executing, and only from the QI and blood classification therapy of starting with, mostly adopts decoction.This dosage form is used trouble, and medication treatment time is long, and the patient is difficult to adhere to treat.

Summary of the invention

The present invention is the treatment demand that satisfies the psoriatic, provides a kind of treatment psoriatic Chinese medicinal capsule, claims 'Tongpiluo ' capsule again.

'Tongpiluo ' capsule of the present invention is that the Chinese medicine ingredients by following weight parts is made:

1 part of Radix Rubiae, 1 part of Caulis Spatholobi, 2 parts of Cornu Bubalis, 3 parts of Herba Patriniae, 1/2 part of Scorpio, 1/3 part of Zaocys, 1/2 part of Agkistrodon, 1/10 part in Radix Glycyrrhizae.

Manufacture method is:

1, Radix Rubiae, Caulis Spatholobi, Herba Patriniae, Radix Glycyrrhizae are decocted filtered juice jointly twice, mix being condensed into medicinal liquid.

2, Zaocys, Scorpio, Agkistrodon, Cornu Bubali are pulverized as substrate, mixed stirring evenly with above-mentioned concentrated medicament.

3, drying, canned one-tenth capsule.

The present invention also can be prepared into any conventional formulation according to the conventional method of Chinese medicine preparation, as makes powder and electuary.

Instructions of taking is: every day, oral 0# capsule was 3 times, each 4 capsules, and one month is a course of treatment, 3 courses of treatment of logotype.

Pharmacological action of the present invention is as follows:

Radix Rubiae: the nature and flavor bitter cold, go into Liver Channel, follow through going into the skin network.Effect: cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling, logical skin network.

Caulis Spatholobi: the nature and flavor hardship, little sweet temperature is gone into the Liver and kidney warp, follows through going into the blood network.Effect: blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, logical blood network.

Cornu Bubali: nature and flavor, bitter salty-cold.Go into liver heart channel, follow through going into the blood network.Effect: heat clearing away, removing heat from blood, detoxifcation, logical blood network, skin network.

Agkistrodon: nature and flavor are sweet, and salty temperature is gone into Liver Channel.Effect: expel wind to dredge collateral, logical liver network, skin network.Property is apt to away scurry, and reaches skin outward, and interior the meridian dredging is the key medicine of expel wind to dredge collateral.

Herba Patriniae: nature and flavor, suffering, hardship is slightly cold, and goes into stomach, large intestine, Liver Channel also follows through going into blood network skin network.Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood stasis dispelling.

Radix Glycyrrhizae: nature and flavor, sweet flat, go into lung taste warp.Effect: and middle QI invigorating, poison of drug separated, the coordinating the actions of various ingredients in a prescription nature and flavor.

Zaocys: nature and flavor are sweet flat, go into Liver Channel, follow through going into the skin network, kind dispelling wind and removing obstruction in the collateral.

Scorpio: nature and flavor Gan Xinping, go into Liver Channel and follow through going into skin network, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.

Common effect: be heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation, collateral dredging blood stasis dispelling.All medicines cooperate, and merit is concentrated one's efforts grand, so receive good effect.

Treatment pathology of the present invention closes the pharmacology innovative point and is a little:

1, psoriasis pathology should belong to pathogen bridle network, stagnation of QI-blood, and pathogen usually intruding into collateral in protracted disease, with the passing of time the blood network is retarded by silt, and poison is given birth in heat-transformation, and it is obstructed that the skin of passing through inside causes the skin network.Starting new effective treatment approach according to the 'Tongpiluo ' capsule that the sick theory of network proposes aspect the treatment psoriasis.Still belong to initiative at home with the sick ens morbi treatment of network psoriasis.

2, can treat the polytype psoriasis, as homeliness type, pustule type, the Folium Styracis Suberifoliae type also is suitable for the heat in blood disease of differential diagnosis in tcm, damp-heat accumulation disease, blood-deficiency and wind-dry disease, Blood stasis, the flourishing card of fire-toxin.

3, making capsule with the spissated method of traditional decocting for Chinese herbal medicine had not only met Chinese medicine decoction and had decocted curative principle but also taking convenience.

The specific embodiment

The specific embodiment of the present invention is not described in detail in this shown in summary of the invention.

For verifying therapeutic effect of the present invention, through accepting out-patient's 100 examples for medical treatment, wherein male 57 examples.Woman's 63 examples.Men and women's ratio is 0.9: 1.Age 4-7 year 7 examples, 10-20 year 30 examples, 20-50 year 40 examples, 23 examples more than 50 years old.Wherein professional cadre 20 people, teacher 15 people, peasant 50 people, workman 8 people, student 7 people.

Diagnostic-type is:

Psoriasis vulgaris 85 people, psoriasis pustulosa 8 people, skin disease psoriasis pustulosa 6 people, arthritis type psoriasis 1 people.

Diagnostic criteria is:

Psoriasis vulgaris damages substantially and is red pimple or maculopapule, and color is red, and the silvery white squama of each layer of surface coverage has thin film phenomenon and petechial hemorrhage phenomenon.Psoriasis pustulosa can be divided into general property and palm toe pustule type, and erythrodermic psoriasis shows as erubescence, and large stretch of wellability erythema is arranged, and has a large amount of squamas to come off.The arthritis type psoriasis, desilver bits sick body is levied outer also with the arthritis pathological changes.

Differential diagnosis in tcm: blood-heat type, blood-dryness type, blood stasis type, fire-toxin type, heat-toxin type.

Therapeutic Method: oral 3 times of every day, each 4 capsules, one month is a course of treatment, 3 courses of treatment of logotype.

Efficacy assessment standard:

Take a turn for the better: each psoriasis pustulosa does not have new skin lesion and occurs after treatment, the erythra colour-darkening, thin out, bleach, have the part erythra to begin to disappear.

Produce effects: the deflorescence area reaches more than 1/2, and white macula appears in back and extremity, and pruritus stops, no longer desquamation.

Recovery from illness: generalized rass all disappears, residual fraction pigmented spots, no longer pruritus.

Invalid: still have new erythra to occur, the skin lesion color is scarlet, enlarged areas.

The treatment observed result sees Table 1.

As can be seen from the table, treat 100 examples with 'Tongpiluo ' capsule of the present invention in 1 year, produce effects 18 examples as a result, 6 examples that take a turn for the better, 75 examples of fully recovering, invalid 1 example, total effective rate 99%.

Further specify curative effect of the present invention below in conjunction with concrete case.

Case one, Wang Wei, man, 38 years old.On January 20, in first visit spring in 2000, the worker of Feicheng agricultural bank.Patient's readme was suffered from psoriasis 30 years, and it is invalid to seek medical advice in many ways for many years, and because of cause the renal tubules sclerosis with immune formulation, so the Chinese medicine of seeking medical advice, disease sees that whole body distributes plaque psoriasis, the purplish red skin scaling that is higher than of color, and red tongue, purple dark, the little Huang of tongue fur is greasy.Tcm diagnosis is a psoriasis vulgaris, the heat in blood blood stasis type.

Oral 'Tongpiluo ' capsule treatment of the present invention, every day 3 times, each 4, after the patient adhered to taking three months, whole body tinea disappeared residual antholeucin speckle.Not recurrence after autumn.Follow up a case by regular visits to and do not recur calendar year 2001 to this year.

Case two, pay quick, woman, 29 years old.Summer in 2002 first visit on June 10,, Fructus Trichosanthis Cucumeroidis shop, Feicheng town villager.Patient's readme was suffered from psoriasis 8 years, once went to Jinan, failed to respond to any medical treatment in ground such as Yanzhou, once with outbreak repeatedly after the hormone medicine treatment.Disease is seen: extremity and shirtfront back are covered with the point-like red rash, and coin shape skin lesion is also arranged, the scarlet pruritus of Off bits back color, the incrustation of head tinea, hair network shape.

Oral 'Tongpiluo ' capsule treatment of the present invention 5 months, every day 3 times, each 4, fully recover in December, 2002, continued to take 3 months for consolidating curative effect.Follow up a case by regular visits to not recurrence so far.

Case three, Zhang Aihong, woman, 40 years old.The Feicheng newly becomes office.First visit in March, 1996.Patient's readme was suffered from psoriasis 6 years, and disease is seen the red macule of the discontented lamellar of whole body, as snow shape, pruritus.

Oral 'Tongpiluo ' capsule treatment of the present invention, macule disappears after 4 months, recovery from illness.Follow up a case by regular visits to not recurrence so far.

Table 1 the present invention treats observed result (totally 100 examples)

Treatment time (moon)	Take a turn for the better		Produce effects		Recovery from illness		Invalid		Effective percentage %
										The example number	Improvement rate %	The example number	Obvious effective rate %	The example number	Cure rate %	The example number	Inefficiency %
	1	30	30	10	10	10	10	50										50	50
2									27	27	18	18	25	25	20	20	80
	3	25	25	25	25	42	42	8										8	92
5									20	20	23	23	55	55	2	2	98
	12	6	6	18	18	75	75	1										1	99

Claims (1)

1, a kind of 'Tongpiluo ' capsule, it is that Chinese medicine ingredients by following weight parts is made:

1 part of Radix Rubiae, 1 part of Caulis Spatholobi, 2 parts of Cornu Bubalis, 3 parts of Herba Patriniae, 1/2 part of Scorpio, 1/3 part of Zaocys, 1/2 part of Agkistrodon, 1/10 part in Radix Glycyrrhizae;

Its manufacture method is:

(1) Radix Rubiae, Caulis Spatholobi, Herba Patriniae, Radix Glycyrrhizae are decocted filtered juice jointly twice, mix being condensed into medicinal liquid;

(2) Zaocys, Scorpio, Agkistrodon, Cornu Bubali are pulverized as substrate, mixed stirring evenly with above-mentioned concentrated medicament;

(3) drying, canned one-tenth capsule.