CN101057912B - Medicine for treating hepatitis and cirrhosis ascites and its preparation method - Google Patents
Medicine for treating hepatitis and cirrhosis ascites and its preparation method Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicament for treating hepatitis and cirrhosis ascites which is prepared from the following raw materials (by weight portion): red ginseng 60-100 parts,white atractylodes rhizome 50-80 parts, borneol 30-50 parts, chicken's gizzard-skin 30-50 parts, red peony root 20-30 parts, blood clam shell 80-100 parts, centipede 40-50 parts, ligumaloes 20-30 parts, earthworm 80-100 parts and polyporus umbellatus 55-80 parts. The medicament is prepared through mixing, grinding into fines, sieving, and can be prepared into powders, tablets, capsules or pills.
Description
(1) technical field
The present invention relates to a kind of medicine for the treatment of hepatitis, cirrhotic ascites.Be the Chinese patent medicine of feedstock production specifically, the invention still further relates to the preparation method of described medicine with the Chinese herbal medicine.
(2) background technology
Cirrhotic ascites is a kind of common chronic progressive external diffusivity hepatic injury.Mainly cause in China by viral hepatitis.Cirrhotic ascites pathogenesis complexity, its pathological characteristic are hepatocellular degeneration, necrosis, new life, simultaneously with diffuse inflammation and connective tissue proliferation, cause the lobules of liver structural deterioration at last and form liver cirrhosis.The treatment cirrhotic ascites does not still have the specific treatment scheme at present, the most frequently used is the operation method that draws water from the abdominal cavity, yet this method have easy infection, complication many, give shortcomings such as bringing patient's misery, and the single Therapeutic Method that taps the abdomen is cured the symptoms, not the disease medical expense height, mortality rate height; Existing medicine, as multiple Chinese patent medicine and many Western medicine such as liver-protecting tablet, Yiganling, sharp liver are grand, mostly be a general antiviral or a nonspecific immunity regulating action, and the Western medicine diuretic initial stage is effective, but its long-term efficacy is poor, just cure the symptoms, not the disease, can not really reach the purpose of treatment cirrhotic ascites, and hepatitis and cirrhotic ascites be a kind of stubborn disease, treatment cycle is long, curative effect is slow, drug dose is big, and medical expense is high; Chinese patent ZL200610068814.4 has put down in writing a kind of Chinese patent medicine for the treatment of cirrhotic ascites, but it contains Alumen and Cornu rhinocerotis powder, and Alumen contains aluminium ion, is unfavorable for the recovery of liver function, and the Cornu rhinocerotis powder belongs to rare valuable medical material, so this scheme is promoted, enforcement is extremely difficult.Therefore, the Chinese and western drugs of existing treatment hepatitis and cirrhotic ascites can not satisfy the needs of extensive patients, presses for the novel drugs that late result is good, medical expense is low.
(3) summary of the invention
The technical problem to be solved in the present invention provides a kind for the treatment of both the principal and secondary aspects of a disease, the treatment hepatitis of late result satisfaction, the medicine of cirrhotic ascites, and has provided its preparation method.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 60 parts of Radix Ginseng Rubra, 80 parts of the Rhizoma Atractylodis Macrocephalaes, 45 parts of Squama Maniss, 50 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 85 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Lignum Aquilariae Resinatum, 100 parts of Radix Raphanis, 70 parts of Polyporus, 40 parts of Radix Angelicae Sinensis, 40 parts of Semen Pharbitidiss, 30 parts of the Radixs Linderae by following former medicine.
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 60～70 parts of Radix Ginseng Rubra, 60 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Squama Maniss, 50 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 30～50 parts of Radix Angelicae Sinensis, 90～100 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Semen Pharbitidiss, 30 parts of Lignum Aquilariae Resinatum, 20～30 parts of the Radix Aucklandiae, 30 parts of the Radixs Linderae, 100 parts of Radix Raphanis, 60 parts of Polyporus, 15～20 parts of Cortex Cinnamomis, 50 parts of Fructus Toosendans, 15～20 parts of Radix Aconiti Lateralis Preparatas by following former medicine.
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 75 parts of Radix Ginseng Rubra, 75 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 25 parts of Radix Paeoniae Rubra, 95 parts of Concha Arcaes, 45 parts of Herba pteridis vittataes, 25 parts of Lignum Aquilariae Resinatum, 95 parts of Radix Raphanis, 55 parts of Polyporus, 35 parts of Radix Angelicae Sinensis, 35 parts of Semen Pharbitidiss, 18 parts of Cortex Cinnamomis, 18 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine.
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 95 parts of Radix Ginseng Rubra, 55 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Squama Maniss, 35 parts of Endothelium Corneum Gigeriae Galli, 28 parts of Radix Paeoniae Rubra, 85 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 20 parts of Lignum Aquilariae Resinatum, 85 parts of Radix Raphanis, 65 parts of Polyporus, 30 parts of the Radixs Linderae, 38 parts of Semen Pharbitidiss, 15 parts of Cortex Cinnamomis, 18 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine.
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 65 parts of Radix Ginseng Rubra, 75 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 95 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Semen Pharbitidiss, 20 parts of Lignum Aquilariae Resinatum, 30 parts of the Radix Aucklandiae, 30 parts of the Radixs Linderae, 80 parts of Radix Raphanis, 55 parts of Polyporus, 20 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine.
A kind of medicine for the treatment of hepatitis, cirrhotic ascites, in weight portion, make: 90 parts of Radix Ginseng Rubra, 70 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 25 parts of Radix Paeoniae Rubra, 90 parts of Concha Arcaes, 45 parts of Herba pteridis vittataes, 35 parts of Semen Pharbitidiss, 30 parts of Lignum Aquilariae Resinatum, 80 parts of Radix Raphanis, 80 parts of Polyporus, 50 parts of Fructus Toosendans by following former medicine.
The preparation method of the medicine of described treatment hepatitis, cirrhotic ascites is: each former medicine mixed grinding is become fine powder, and cross 100～200 mesh sieves, and promptly make powder, also the fine powder after sieving can be pressed into tablet, also fine powder can be incapsulated, refine into pill after also can in fine powder, adding Mel.
The preparation method of the medicine of described treatment hepatitis, cirrhotic ascites is: the capsule of packing into No. 0 of the fine powder after will sieving, every capsules dress 0.5g fine powder is made capsule formulation.
The preparation method of the medicine of described treatment hepatitis, cirrhotic ascites is: refine into pill after the back of sieving adds the Mel of 500～800 weight portions in the fine powder, every ball weighs 8～10 grams.
The usage and the consumption of the medicine of described treatment hepatitis, cirrhotic ascites: make capsule No. 0, take 15～20 at every turn, eat three meals a day and swallow back 30 minutes the time; Make 9 grams during pills, obey 2 balls at every turn, eat three meals a day and swallow back 30 minutes the time; Other is taken more than dosage form reference.
Chinese patent medicine pharmacology analysis of the present invention:
Cirrhotic ascites can belong to gas, water, blood, the tympanites due to parasitic infestation scope of motherland's medical science.Although the pathogenesis of liver cirrhosis is complicated unusually, its disease is folded existing, and it must decrease liver transmitting into the spleen and kidney eventually, hepatic depression is held back, certainly will take advantage of and attack spleen soil, dysfunction of the spleen in transportation, clear YANG failing to ascend, foodstuff essence is little can not support whole body, turbid YIN failing to descend, clear QI being mixed up with turbid QI is in the turbid retention body of water damp-phlegm, cause coagulation of QI-blood, channel tunnel network road obstruction.So this medicine is with the blood stasis dispelling water collateral dredging that disappears, strengthening vital QI to eliminate pathogenic factors, spleen invigorating protects the liver and is aim, runs through the treatment utilization all the time.In the raw materials used medicine of the present invention, be monarch with ginseng, art, Radix Paeoniae Rubra, Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling are rubbed the medicine into softening hard tissues such as Squama Manis, Concha Arcaes, to promote hepatocellular recovery, to changing the liver form, adjust immunity of organism and play an important role; 5 enter a profession Herba pteridis vittataes, Semen Pharbitidis of water toxin expelling and so on are attacked and are mended with the side, and revisal is eliminating evil, reaches the lasting purpose of late result; Be equipped with the QI regulating medicine Radix Aucklandiae, the Radix Linderae, Lignum Aquilariae Resinatum etc., have the synergism that the capable water of gas is also gone; Radix Raphani is rich in high protein, and the tonify deficiency relieving distension is arranged, and replenishes albumin, corrects the function of albumins/globulins ratio inversion, and the effect of tangible diuresis is arranged.Clinical application is invented the appropriate to the occasion flexible of described medicine, as the hepatitis b surface antigen positive person, should add Nidus Vespae, Radix Sophorae Flavescentis etc. in this medicine; The ascites severe patient should be joined clothes Pill for Relieving Ascites; The hepatic and renal YIN deficiency should be joined the clothes LIUWEI DIHUANG WAN; Liver,spleen,kidney three dirty being injured, insufficiency of the spleen then can not controlling the water circulation, the then difficulty in urination due to hypofunction of the kidney of suffering from a deficiency of the kidney, the abdominal distention loose stool appears, the soreness of waist is urinated few, and moist and slippery fur is white, and deep-slow pulse is unable, water is wet to stay, the clinical intractable cirrhotic ascites of real genus, pay rise at the bottom of every adding Radix Aconiti Lateralis Preparata, the Cortex Cinnamomi still, the gate of vitality is mended in training, warm kidney fire is often received satisfactory effect with circulation of qi promotingization.
The present invention has actively useful effect:
The silt of having of this medicine disappear water collateral dredging, Ruan Jian Xiao Disorder, set upright spleen invigorating and protect the liver, promote the hepatocyte that damages to recover, increase the effect of body immunity; Its indication: various hepatitis early, the emaciation and sallow complexion due to mid-term, weak, the hepatosplenomegaly of poor appetite; The big blue veins of hepatitis tripe in latter stage, one's belly is tight as a drum (cirrhotic ascites) and the liver function transaminase occupies that height does not fall, the enhancing of liver diffusivity echo is difficult to the changer for a long time.
2. formula compatibility of the present invention is scientific and reasonable, and each raw material complementary action is remarkable, has no side effect, and each medical material of distinguishing the flavor of is cheap and easy to get, and late result is good.
The inventor practises medicine year surplus in the of 40, and utilization the present invention's Drug therapy acute, chronic hepatitis, hepatitis B, early stage liver cirrhosis, cirrhotic ascites 130 many cases have obtained satisfied cure rate and late result.Only enumerate some concrete case explanations in recent years below:
1. Wu, the woman, 59 years old, Shandong, Gongyi City village village people found hepatitis B 5 years.Live in the Zhengzhou provincial hospital in April, 1993, chemical examination shows: glutamate pyruvate transaminase 209u/L, glutamic oxaloacetic transaminase, GOT 451u/L, r-transpeptidase 43u/L; Six of hepatitis B: HBsAg (+), HBeAg (+), anti-HBs (-), anti-HBe (-), anti-HBc (+), anti-HBcAbLgM (+).Be diagnosed as hepatitis B, cirrhotic ascites.Protect the liver, replenish albumin through diuretic, comprehensive therapies such as intramuscular injection anti-hepatitis B immune ribonucleic acid are surplus January, and abdominal circumference increases to 130cm, and it is very little to urinate behind the application furosemide, and it is very difficult to breathe, walk, and the state of an illness is critical leaves hospital.The inventor examines meeting black Mental fatigue, indigestion and loss of appetite loose stool, and light red tongue matter is fat, and moist and slippery fur is white, and deep-thready pulse is slow.Visible several spider angiomas of neck surface, chest and back is dispersed in the cerise petechia, and the cardiopulmonary auscultation is no abnormal.Pot belly, the liver palpation of spleen is dissatisfied, abdominal part can be kowtowed out shifting dullness, sign of ascites (Their-registered), the visible severe pitting edema of two lower limb.Ultrasonic investigation prompting: liver cirrhosis, ascites.The medicine of taking among the embodiment 8 adds Poria, Rhizoma Zingiberis, RADIX ACONITI LATERALIS PREPARATA etc., warm spleen soil, warm kidney fire, gate of vitality's fire rises, rising functioning of bladder, discharge clear watery stool half basin (about 4000ml) every day, ascites obviously disappeared in 7 days, and spirit takes a turn for the better, diet heightens, but out-of-bed activity, ascites disappears fully after 2 weeks, and the abdominal circumference retraction is 75cm.The back is with this medicine after treatment drug withdrawal in 8 months.Follow up a case by regular visits to stable curative effect after 4 years, can be engaged in housework.On May 12nd, 1996 was removed HBsAg (+) six of province the People's Hospital check hepatitis B, and outside the HBcAb (+), other test rating is all normal.
2. Zhang, the man, 64 years old, Gongyi Da Yugou town general mountain range people from village, live Gongyi City hospital in July, 1994, is diagnosed as cirrhotic ascites.Laboratory examination shows: TB 24.3umol/L, TTT 5u, the normal u of GPT, HBsAg (+), total protein 50g/L, albumin 28g/L, globulin 28g/L, albumin: globulin=0.78: 1, alpha-fetoprotein＜25ng/L.The epigastrium CT scan shows: 1. liver diffuse lesion, splenomegaly 54mm; 2. ascites.Hospitalization is surplus January, and the state of an illness continues to worsen, and is critically ill and leaves hospital.The inventor examines and sees that patient's complexion is gloomy simple and unadorned, anasarca, and abdominal distention such as distension, vena epigastrica appears, the walking difficulty that crouched, urine is few, and the tongue white fur is sliding, deep-slow pulse.Pot belly, the liver palpation of spleen is dissatisfied, sign of ascites (Their-registered), the visible severe pitting edema of two lower limb.Took orally 20 days with the embodiment of the invention 15 described medicine adapted Pill for Relieving Ascites, anasarca disappears gradually, and diet heightens, and January, water base of venter posterior disappeared, diet, the walking as usual, antisecosis was withdrawn Pill for Relieving Ascites, with disease plus-minus after treatment 6 months, January 12 nineteen ninety-five, B ultrasonic was detected, liver form, echo before take an evident turn for the better, the thick 37mm of spleen, and echo is even.TB:1.0mg/L, TTT4u, GPT:40 ↓ u, HBsAg (-); Total protein 5.25g/dL, albumin 2.8g/dL, globulin 2.55g/dL, albumin: globulin=1.05: 1.Follow up a case by regular visits to after 2 years, do not have recurrence, body and the spirit is healthy and vigorous, recovers work capacity.
3. Song, man, 40 years old.Found hepatitis B 5 years, sense abdominal distention in 1993, hepatalgia, at certain hospital's ultrasonic investigation: 1. liver diffusivity echo changes; 2. the thick 44mm of spleen.Once used Chinese and western drugs treatment 3 years, symptom increases the weight of day by day, and repeatedly through ultrasonic investigation, the liver spleen does not have improvement.Took this medicine 15 days, abdominal distention obviously alleviates, and takes 2 months, and abdominal distention, hepatalgia disappear, the ultrasound wave check, and liver diffusivity echo changes, and before takes a favorable turn, and the spleen retraction is 38mm.Come the inventor to locate to obey embodiment 18 described medicines after 4 months, ultrasound wave check, liver spleen form, size, echo are all normal.After treatment 3 months, HBsAg tests negative, and HBeAg tests positive, shows hepatitis B recuperating medicine.Check does not have repeatedly after 1 year, and other test rating is all normal.
4. Zhai, woman, 49 years old, the Jia Jinkou of Gongyi City people from village.In October, 1994, the state of an illness took a turn for the better to some extent because of the cirrhotic ascites Yuanyang County hospitalize of making a special trip to a certain place.Send out because of ascites June nineteen ninety-five again, in town, the how tame hospitalize in city, poor effect.Locate to go to a doctor to the inventor August nineteen ninety-five, and patient's mind is clear, spirit is poor, the dark green grass or young crops of complexion, and the little xanthochromia of whole skin and sclera is not seen spider angioma, liver palm etc.Pot belly, the liver palpation of spleen is dissatisfied, and abdominal part can be kowtowed out shifting dullness, sign of ascites (Their-registered), the big capsule enclosed mass of the visible eggplant of right side groin, clear border, but the Huan Na abdominal cavity of touching, the visible severe pitting edema of two lower limb.Laboratory examination shows: total bilirubin 1.8mg/dL, TTT 10u, GPT 200 ↑ u; Five indexes of hepatitis b: HBsAg (+), anti-HBs (+), anti-HBG (+).B ultrasonic prompting: 1. liver cirrhosis; 2. ascites.Diagnosis: 1. cirrhotic ascites; 2. right oblique inguinal hernia.The embodiment of the invention 9 described medicines for oral administration, spirit was clearly better in 1 month, and appetite increases, and ascites obviously disappears.Diet is normal after 2 months, and abdominal distention disappears, and ascites disappears substantially, sign of ascites (+), and hernia is obviously dwindled.Ascites disappeared fully in 3 months, sign of ascites (-), and two lower limb concavity edema disappear.B ultrasonic check after 5 months, the liver form has obvious change, and echo, sign of ascites (-), hernia disappear.Following up a case by regular visits to after 1 year does not have recurrence, recovers work capacity.
5. Wang, man, 29 years old, the Xiao Guan of Gongyi City town Xiao Guan people from village.October nineteen ninety-five is because of cirrhotic ascites certain section hospital that firmly breaks a seal.Surplus in the of expensive 20,000 yuan, the state of an illness continues to worsen, leave hospital the back in April, 1996 inventor that comes locate to go to a doctor patient's face black Mental fatigue, anasarca, enlarged abdomen blue veins, abdominal circumference 128cm, the liver palpation of spleen is dissatisfied, ascites symptoms (++ ++), two severe lower extremity pitting edemas involve scrotum.B ultrasonic, epigastrium CT all point out: liver cirrhosis, splenomegaly, ascites.Five indexes of hepatitis b: 1. 4. 5. positive.The embodiment of the invention 10 described medicines for oral administration are after one month, and two lower limb, scrotum and anasarca obviously disappear, and appetite heightens.Water base of venter posterior disappeared in 2 months.Ascites disappears fully after 4 months, ascites symptoms (-), and abdominal circumference is condensed to 85cm.
6. Zhang, the man, 64 years old, the He Luo of Gongyi City town Jin Kou people from village suffered from acute icterohepatitis, clinical cure in 1986.(on February 8th, 1996) interruption heating after 10 years, poor appetite, abdominal distention, two lower limb and anasarca, surplus at town's hospitalize first quarter moon, invalid and the inventor that comes locates to go to a doctor, 38.4 ℃ of patient temperatures, and cardiopulmonary are normal, distention and fullness in the abdomen, abdominal part can be deducted shifting dullness, sign of ascites (++), the visible pitting edema of two lower limb.Chemical examination liver function: TB 1.04mg/d, TTT 7u, GPT 69u, HBsAg (+), TG＜25.B ultrasonic is detected: liver volume dwindles, form is not normal, and piping moves towards distortion, and area reduces, the thick 52mm of spleen.Come the inventor to go out to clothes embodiment 6 described bolus of drug, three times on the one, one time 2 ball, take 4 months after, anasarca and ascites disappear, subjective symptoms is obviously improved, sign of ascites (-), liver function is normal, HBsAg (-); After treatment 13 months, clinical cure can be managed general light physical labor.Detect through B ultrasonic: the liver form is still normal, and liver parenchyma echo is still even, and the tube structure trend is normal, and the spleen retraction is 46mm, and echo is even, visits and does not have recurrence in 5 years.
7. wear certain, woman, 11 years old, big valley ditch mineral bureau one ore deposit families of workers and staff, because of heating, poor appetite, nausea and vomiting companion's skin and one week of yellow sclera, go to Gongyi Traditional Chinese Medical Hospital to go to a doctor on July 2nd, 2002, look into liver function: TB45.3umol/L, TTT9u, GPT:733.3u/L, T76.7, A:40.1, G:36.6, A/G=1.1: 1, be diagnosed as acute icterohepatitis, come the inventor to locate to take embodiment 14 described medicines, heating ends after 7 days, appetite increases, no nausea and vomiting, whole skin and yellow sclera obviously disappear, and continue this medicine of clothes to 15 days, clinical symptom disappearance, xanthochromia (-).Liver function check on July 17: TB 412.7umol/L, TTT 5u, GPT 29.9u/L, T 70.1, A:45.6, G:24.5, A/G=1.85: 1, this medicine of clothes after treatment first quarter moon that continues was visited 3 years, did not have recurrence, and is healthy.
(4) specific embodiment
Embodiment 1: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by the following former medicine of respectively distinguishing the flavor of: Radix Ginseng Rubra 60g, Rhizoma Atractylodis Macrocephalae 50g, Squama Manis 30g, Endothelium Corneum Gigeriae Galli 30g, Radix Paeoniae Rubra 20g, Concha Arcae 80g, Herba pteridis vittatae 40g, Lignum Aquilariae Resinatum 20g, Radix Raphani 80g, Polyporus 50g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves, promptly make powder, take 7～10g, three times on the one at every turn.
Embodiment 2: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 100g, white 80g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Concha Arcae 100g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 30g, Radix Raphani 100g, Polyporus 80g, Radix Angelicae Sinensis 50g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves, the capsule of packing into No. 0 of the fine powder after sieving, every capsules dress 0.5g fine powder is taken 15～20, three times on the one at every turn.
Embodiment 3: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 65g, Rhizoma Atractylodis Macrocephalae 60g, Squama Manis 35g, Endothelium Corneum Gigeriae Galli 35g, Radix Paeoniae Rubra 25g, Concha Arcae 85g, Herba pteridis vittatae 40g, Lignum Aquilariae Resinatum 20g, Radix Raphani 85g, Polyporus 60g, Radix Aconiti Lateralis Preparata 15g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 180 mesh sieves, refine into pill behind the adding 600g Mel in fine powder, the heavy 10g of every ball takes 2 balls, three times on the one at every turn.
Embodiment 4: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 90g, Rhizoma Atractylodis Macrocephalae 70g, Squama Manis 45g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Concha Arcae 90g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 30g, Radix Raphani 100g, Polyporus 70g, Radix Angelicae Sinensis 30g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 150 mesh sieves, the fine powder after sieving is pressed into tablet, every 0.5g takes 15～20 at every turn, three times on the one.
Embodiment 5: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 80g, Rhizoma Atractylodis Macrocephalae 50g, Squama Manis 35g, Endothelium Corneum Gigeriae Galli 40g, Radix Paeoniae Rubra 25g part, Concha Arcae 80g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 25g, Radix Raphani 80g, Polyporus 60g, Radix Angelicae Sinensis 30g, Semen Pharbitidis 30g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves,, take 15～20 at every turn the fine powder capsule of packing into No. 0.
Embodiment 6: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 60g, Rhizoma Atractylodis Macrocephalae 80g, Squama Manis 45g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g part, Concha Arcae 85g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 30g, Radix Raphani 100g, Polyporus 70g, Radix Angelicae Sinensis 40g, Semen Pharbitidis 40g, Radix Linderae 30g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 200 mesh sieves, refine into pill behind the adding 750g Mel in fine powder, the heavy 10g of every ball takes 2, three times on the one at every turn.
Embodiment 7: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 100g, Rhizoma Atractylodis Macrocephalae 55g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 30g, Radix Paeoniae Rubra 20g part, Concha Arcae 80g, Herba pteridis vittatae 40g, Lignum Aquilariae Resinatum 20g, Radix Aucklandiae 30g, Radix Raphani 90g, Polyporus 60g, Radix Angelicae Sinensis 50g, Semen Pharbitidis 35g, Cortex Cinnamomi 15g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves, promptly make powder.
Embodiment 8: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 70g, Rhizoma Atractylodis Macrocephalae 60g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Concha Arcae 100g, Herba pteridis vittatae 50g, Semen Pharbitidis 30g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae 30g, Radix Linderae 30g, Radix Raphani 100g, Polyporus 60g, Cortex Cinnamomi 20g, Fructus Toosendan 50g, Radix Aconiti Lateralis Preparata 15g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 200 mesh sieves, in fine powder, refine into pill, every ball 9g behind the adding Mel 800g.
Embodiment 9: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 60g, Rhizoma Atractylodis Macrocephalae 60g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 50g, Concha Arcae 90g, Herba pteridis vittatae 50g, Semen Pharbitidis 30g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae 20g, Radix Linderae 30g, Radix Raphani 100g, Polyporus 60g, Cortex Cinnamomi 15g, Fructus Toosendan 50g, Radix Aconiti Lateralis Preparata 20g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves, in fine powder, refine into pill, every ball 9g behind the adding Mel 800g.
Embodiment 10: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 75g, Rhizoma Atractylodis Macrocephalae 75g, Squama Manis 40g, Endothelium Corneum Gigeriae Galli 45g, Radix Paeoniae Rubra 25g, Concha Arcae 95g, Herba pteridis vittatae 45g, Lignum Aquilariae Resinatum 25g, Radix Raphani 95g, Polyporus 55g, Radix Angelicae Sinensis 35g, Semen Pharbitidis 35g, Cortex Cinnamomi 18g, Radix Aconiti Lateralis Preparata 18g, Fructus Toosendan 50g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 200 mesh sieves, in fine powder, refine into pill behind the adding Mel 700g, the heavy 8g of every ball.
Embodiment 11: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: 20 parts of Radix Ginseng Rubra 100g, Rhizoma Atractylodis Macrocephalae 50g, Squama Manis 40g, Endothelium Corneum Gigeriae Galli 40g, Radix Paeoniae Rubra 30g, Concha Arcae 100g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae 30g, Radix Raphani 80g, Polyporus 60g, Radix Angelicae Sinensis 30g, Semen Pharbitidis 40g, Cortex Cinnamomis.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 200 mesh sieves, fine powder is pressed into tablet.
Embodiment 12: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 90g, Rhizoma Atractylodis Macrocephalae 60g, Squama Manis 40g, Endothelium Corneum Gigeriae Galli 35g, Radix Paeoniae Rubra 30g, Concha Arcae 90g, Herba pteridis vittatae 40g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae 30g, Radix Linderae 30g, Radix Raphani 90g, Polyporus 80g, Radix Angelicae Sinensis 30g, Semen Pharbitidis 40g, Cortex Cinnamomi 15g, Radix Aconiti Lateralis Preparata 18g, Fructus Toosendan 50g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 100 mesh sieves, refine into pill behind the adding 800g Mel in fine powder, the heavy 8g of every ball takes 2, three times on the one at every turn.
Embodiment 13: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 75g, Rhizoma Atractylodis Macrocephalae 55g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 45g, Radix Paeoniae Rubra 25g, Concha Arcae 100g, Herba pteridis vittatae 40g, Semen Pharbitidis 30g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae 30g, Radix Linderae 30g, Radix Raphani 100g, Polyporus 60g, Cortex Cinnamomi 20g, Fructus Toosendan 50g, Radix Aconiti Lateralis Preparata 15g.
Above-mentioned former medicine mixed grinding is become fine powder, and cross 200 mesh sieves, in fine powder, refine into pill, every ball 9g behind the adding Mel 800g.
Embodiment 14: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 95g, Rhizoma Atractylodis Macrocephalae 55g, Squama Manis 30g, Endothelium Corneum Gigeriae Galli 35g, Radix Paeoniae Rubra 28g, Concha Arcae 85g, Herba pteridis vittatae 50g, Semen Pharbitidis 38g, Lignum Aquilariae Resinatum 20g, Radix Linderae 30g, Radix Raphani 85g, Polyporus 65g, Cortex Cinnamomi 15g, Fructus Toosendan 50g, Radix Aconiti Lateralis Preparata 18g.
Preparation method is with embodiment 1.
Embodiment 15: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 65g, Rhizoma Atractylodis Macrocephalae 75g, Squama Manis 40g, Endothelium Corneum Gigeriae Galli 45g, Radix Paeoniae Rubra 30g, Concha Arcae 95g, Herba pteridis vittatae 50g, Semen Pharbitidis 30g, Lignum Aquilariae Resinatum 20g, Radix Aucklandiae 30g, Radix Linderae 30g, Radix Raphani 80g, Polyporus 55g, Fructus Toosendan 50g, Radix Aconiti Lateralis Preparata 20g.
Preparation method is with embodiment 2.
Embodiment 16: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 78g, Rhizoma Atractylodis Macrocephalae 65g, Squama Manis 48g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Concha Arcae 90g, Herba pteridis vittatae 45g, Semen Pharbitidis 35g, Lignum Aquilariae Resinatum 20g, Radix Linderae 30g, Radix Raphani 80g, Polyporus 55g, Fructus Toosendan 50g.
Preparation method is with embodiment 3.
Embodiment 17: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 68g, Rhizoma Atractylodis Macrocephalae 75g, Squama Manis 50g, Endothelium Corneum Gigeriae Galli 50g, Radix Paeoniae Rubra 30g, Concha Arcae 100g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 30g, Radix Linderae 20g, Radix Raphani 100g, Polyporus 70g, Fructus Toosendan 48g.
Preparation method is with embodiment 4.
Embodiment 18: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 90g, Rhizoma Atractylodis Macrocephalae 70g, Squama Manis 30g, Endothelium Corneum Gigeriae Galli 45g, Radix Paeoniae Rubra 25g, Concha Arcae 90g, Herba pteridis vittatae 45g, Semen Pharbitidis 35g, Lignum Aquilariae Resinatum 30g, Radix Raphani 80g, Polyporus 80g, Fructus Toosendan 50g.
Preparation method is with embodiment 5.
Embodiment 19: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 68g, Rhizoma Atractylodis Macrocephalae 50g, Radix Angelicae Sinensis 40g, Squama Manis 40g, Endothelium Corneum Gigeriae Galli 30g, Radix Paeoniae Rubra 20g, Concha Arcae 78g, Herba pteridis vittatae 50g, Lignum Aquilariae Resinatum 25g, Radix Aucklandiae 30g, Radix Raphani 95g, Polyporus 75g, Cortex Cinnamomi 20g.
Preparation method is with embodiment 8.
Embodiment 20: a kind of medicine for the treatment of hepatitis, cirrhotic ascites, make by following former medicine: Radix Ginseng Rubra 70g, Rhizoma Atractylodis Macrocephalae 60g, Squama Manis 48g, Endothelium Corneum Gigeriae Galli 48g, Radix Paeoniae Rubra 28g, Concha Arcae 100g, Herba pteridis vittatae 50g, Semen Pharbitidis 35g, Lignum Aquilariae Resinatum 30g, Radix Linderae 30g, Radix Raphani 100g, Polyporus 60g, Cortex Cinnamomi 20g.
Preparation method is with embodiment 9.
Claims (9)
1. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 60 parts of Radix Ginseng Rubra, 80 parts of the Rhizoma Atractylodis Macrocephalaes, 45 parts of Squama Maniss, 50 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 85 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Lignum Aquilariae Resinatum, 100 parts of Radix Raphanis, 70 parts of Polyporus, 40 parts of Radix Angelicae Sinensis, 40 parts of Semen Pharbitidiss, 30 parts of the Radixs Linderae by following former medicine in weight portion.
2. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 60～70 parts of Radix Ginseng Rubra, 60 parts of the Rhizoma Atractylodis Macrocephalaes, 50 parts of Squama Maniss, 50 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 30～50 parts of Radix Angelicae Sinensis, 90～100 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Semen Pharbitidiss, 30 parts of Lignum Aquilariae Resinatum, 20～30 parts of the Radix Aucklandiae, 30 parts of the Radixs Linderae, 100 parts of Radix Raphanis, 60 parts of Polyporus, 15～20 parts of Cortex Cinnamomis, 50 parts of Fructus Toosendans, 15～20 parts of Radix Aconiti Lateralis Preparatas by following former medicine in weight portion.
3. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 75 parts of Radix Ginseng Rubra, 75 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 25 parts of Radix Paeoniae Rubra, 95 parts of Concha Arcaes, 45 parts of Herba pteridis vittataes, 25 parts of Lignum Aquilariae Resinatum, 95 parts of Radix Raphanis, 55 parts of Polyporus, 35 parts of Radix Angelicae Sinensis, 35 parts of Semen Pharbitidiss, 18 parts of Cortex Cinnamomis, 18 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine in weight portion.
4. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 95 parts of Radix Ginseng Rubra, 55 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Squama Maniss, 35 parts of Endothelium Corneum Gigeriae Galli, 28 parts of Radix Paeoniae Rubra, 85 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 20 parts of Lignum Aquilariae Resinatum, 85 parts of Radix Raphanis, 65 parts of Polyporus, 30 parts of the Radixs Linderae, 38 parts of Semen Pharbitidiss, 15 parts of Cortex Cinnamomis, 18 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine in weight portion.
5. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 65 parts of Radix Ginseng Rubra, 75 parts of the Rhizoma Atractylodis Macrocephalaes, 40 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Radix Paeoniae Rubra, 95 parts of Concha Arcaes, 50 parts of Herba pteridis vittataes, 30 parts of Semen Pharbitidiss, 20 parts of Lignum Aquilariae Resinatum, 30 parts of the Radix Aucklandiae, 30 parts of the Radixs Linderae, 80 parts of Radix Raphanis, 55 parts of Polyporus, 20 parts of Radix Aconiti Lateralis Preparatas, 50 parts of Fructus Toosendans by following former medicine in weight portion.
6. medicine for the treatment of hepatitis, cirrhotic ascites, it is characterized in that:, make: 90 parts of Radix Ginseng Rubra, 70 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Squama Maniss, 45 parts of Endothelium Corneum Gigeriae Galli, 25 parts of Radix Paeoniae Rubra, 90 parts of Concha Arcaes, 45 parts of Herba pteridis vittataes, 35 parts of Semen Pharbitidiss, 30 parts of Lignum Aquilariae Resinatum, 80 parts of Radix Raphanis, 80 parts of Polyporus, 50 parts of Fructus Toosendans by following former medicine in weight portion.
7. the preparation method of the medicine of the described treatment hepatitis of any claim of claim 1～6, cirrhotic ascites, it is characterized in that: each former medicine mixed grinding is become fine powder, and mistake 100～200 mesh sieves, promptly make powder, also the fine powder after sieving can be pressed into tablet, also fine powder can be incapsulated, refine into pill after also can in fine powder, adding Mel.
8. the preparation method of the medicine of treatment hepatitis according to claim 7, cirrhotic ascites is characterized in that: the capsule of packing into No. 0 of the fine powder after will sieving, every capsules dress 0.5g fine powder is made capsule formulation.
9. the preparation method of the medicine of treatment hepatitis according to claim 7, cirrhotic ascites is characterized in that: refine into pill after adding the Mel of 500～800 weight portions in the fine powder, every ball weighs 8～10 grams.
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| CN1314164A (en) * | 2000-08-24 | 2001-09-26 | 张汉三 | Method for preparing liver recovery decoction for curing liver disease |
| CN1404865A (en) * | 2002-10-30 | 2003-03-26 | 方永升 | Preparatory Chinese medicine for treating liver disease |
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| CN1314164A (en) * | 2000-08-24 | 2001-09-26 | 张汉三 | Method for preparing liver recovery decoction for curing liver disease |
| CN1404865A (en) * | 2002-10-30 | 2003-03-26 | 方永升 | Preparatory Chinese medicine for treating liver disease |
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