CN101054386A - Method of synthesizing cefuroxime - Google Patents
Method of synthesizing cefuroxime Download PDFInfo
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- CN101054386A CN101054386A CN 200610054593 CN200610054593A CN101054386A CN 101054386 A CN101054386 A CN 101054386A CN 200610054593 CN200610054593 CN 200610054593 CN 200610054593 A CN200610054593 A CN 200610054593A CN 101054386 A CN101054386 A CN 101054386A
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- cefuroxime
- acid
- sodium
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- cefuroxime sodium
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CNB2006100545935A CN100564382C (en) | 2006-11-12 | 2006-11-12 | The synthetic method of Cefuroxime sodium |
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CNB2006100545935A CN100564382C (en) | 2006-11-12 | 2006-11-12 | The synthetic method of Cefuroxime sodium |
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CN101054386A true CN101054386A (en) | 2007-10-17 |
CN100564382C CN100564382C (en) | 2009-12-02 |
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CNB2006100545935A Expired - Fee Related CN100564382C (en) | 2006-11-12 | 2006-11-12 | The synthetic method of Cefuroxime sodium |
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Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101671349B (en) * | 2009-08-28 | 2010-12-15 | 海南美大制药有限公司 | New method for preparing cefuroxime sodium compound |
CN101967156A (en) * | 2010-09-26 | 2011-02-09 | 石药集团石家庄高科医药科技开发有限公司 | Method for recrystallizing cefuroxime sodium |
CN101475579B (en) * | 2009-01-20 | 2011-02-09 | 广州白云山天心制药股份有限公司 | Stable cefuroxime sodium and preparation thereof |
CN102093390A (en) * | 2011-01-27 | 2011-06-15 | 蚌埠丰原涂山制药有限公司 | Method for preparing cefuroxime acid |
CN102134252A (en) * | 2010-01-27 | 2011-07-27 | 四平市精细化学品有限公司 | Preparation method of high-purity cefuroxime acid |
CN101812076B (en) * | 2009-02-24 | 2012-05-30 | 丽珠医药集团股份有限公司 | Cefuroxime sodium and preparation method thereof |
CN103102357A (en) * | 2013-02-21 | 2013-05-15 | 广东立国制药有限公司 | Synthesis method of cefuroxime sodium |
CN103145734A (en) * | 2013-03-29 | 2013-06-12 | 山东罗欣药业股份有限公司 | Cefuroxime lysine and preparation thereof |
CN103159784A (en) * | 2013-03-29 | 2013-06-19 | 山东罗欣药业股份有限公司 | Cefuroxime lysine and preparation thereof |
CN104327100A (en) * | 2014-09-30 | 2015-02-04 | 华北制药河北华民药业有限责任公司 | Preparation technology of high-purity flomoxef sodium |
CN104774211A (en) * | 2015-04-27 | 2015-07-15 | 四川制药制剂有限公司 | Preparation technique of cefuroxime sodium for injection |
CN104906034A (en) * | 2015-05-28 | 2015-09-16 | 浙江长典医药有限公司 | Cefuroxime sodium and low-sodium carrier drug composition for children |
CN104961749A (en) * | 2015-06-15 | 2015-10-07 | 海南灵康制药有限公司 | Novel industrial crystallizing technology for cefuroxime sodium |
CN106565748A (en) * | 2016-09-30 | 2017-04-19 | 华北制药河北华民药业有限责任公司 | Preparation method for cefuroxime sodium and preparation thereof |
CN107652306A (en) * | 2017-10-24 | 2018-02-02 | 北京红太阳药业有限公司 | A kind of Cefuroxime Sodium crystal-form compound |
CN108066338A (en) * | 2017-12-26 | 2018-05-25 | 金华智济药物科技合伙企业(有限合伙) | New antibiotic composition when prevention and treatment aerobic bacteria and anaerobic bacteria mixed infection and preparation method thereof |
CN108440568A (en) * | 2018-04-11 | 2018-08-24 | 广东立国制药有限公司 | A kind of preparation method of descarbamoyl cefuroxime |
CN109851627A (en) * | 2018-12-21 | 2019-06-07 | 广州白云山天心制药股份有限公司 | A kind of preparation method of Cefuroxime Sodium crystal-form compound |
CN114292282A (en) * | 2021-12-09 | 2022-04-08 | 山东金特安全科技有限公司 | Method for synthesizing cefuroxime sodium based on continuous flow reaction technology |
CN114618410A (en) * | 2022-03-03 | 2022-06-14 | 清华大学 | Method for dissolving D-7-ACA by using microreactor |
CN115650995A (en) * | 2022-10-18 | 2023-01-31 | 浙江东盈药业有限公司 | Preparation method of cefuroxime sodium |
WO2023050596A1 (en) * | 2021-09-30 | 2023-04-06 | 海南海灵化学制药有限公司 | Process for preparing cefuroxime sodium for injection |
-
2006
- 2006-11-12 CN CNB2006100545935A patent/CN100564382C/en not_active Expired - Fee Related
Cited By (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101475579B (en) * | 2009-01-20 | 2011-02-09 | 广州白云山天心制药股份有限公司 | Stable cefuroxime sodium and preparation thereof |
CN101812076B (en) * | 2009-02-24 | 2012-05-30 | 丽珠医药集团股份有限公司 | Cefuroxime sodium and preparation method thereof |
CN101671349B (en) * | 2009-08-28 | 2010-12-15 | 海南美大制药有限公司 | New method for preparing cefuroxime sodium compound |
CN102134252A (en) * | 2010-01-27 | 2011-07-27 | 四平市精细化学品有限公司 | Preparation method of high-purity cefuroxime acid |
CN102134252B (en) * | 2010-01-27 | 2013-03-27 | 四平市精细化学品有限公司 | Preparation method of high-purity cefuroxime acid |
CN101967156A (en) * | 2010-09-26 | 2011-02-09 | 石药集团石家庄高科医药科技开发有限公司 | Method for recrystallizing cefuroxime sodium |
CN101967156B (en) * | 2010-09-26 | 2012-07-18 | 石药集团中诺药业(石家庄)有限公司 | Method for recrystallizing cefuroxime sodium |
CN102093390A (en) * | 2011-01-27 | 2011-06-15 | 蚌埠丰原涂山制药有限公司 | Method for preparing cefuroxime acid |
CN102093390B (en) * | 2011-01-27 | 2012-08-22 | 蚌埠丰原涂山制药有限公司 | Method for preparing cefuroxime acid |
CN103102357A (en) * | 2013-02-21 | 2013-05-15 | 广东立国制药有限公司 | Synthesis method of cefuroxime sodium |
CN103102357B (en) * | 2013-02-21 | 2016-01-13 | 广东立国制药有限公司 | A kind of synthetic method of Cefuroxime sodium |
CN103159784B (en) * | 2013-03-29 | 2015-09-09 | 山东罗欣药业集团股份有限公司 | A kind of cefuroxime lysine and preparation thereof |
CN103159784A (en) * | 2013-03-29 | 2013-06-19 | 山东罗欣药业股份有限公司 | Cefuroxime lysine and preparation thereof |
CN103145734A (en) * | 2013-03-29 | 2013-06-12 | 山东罗欣药业股份有限公司 | Cefuroxime lysine and preparation thereof |
CN103145734B (en) * | 2013-03-29 | 2016-05-04 | 山东罗欣药业集团股份有限公司 | A kind of cefuroxime lysine and preparation thereof |
CN104327100A (en) * | 2014-09-30 | 2015-02-04 | 华北制药河北华民药业有限责任公司 | Preparation technology of high-purity flomoxef sodium |
CN104774211A (en) * | 2015-04-27 | 2015-07-15 | 四川制药制剂有限公司 | Preparation technique of cefuroxime sodium for injection |
CN104906034A (en) * | 2015-05-28 | 2015-09-16 | 浙江长典医药有限公司 | Cefuroxime sodium and low-sodium carrier drug composition for children |
CN104961749A (en) * | 2015-06-15 | 2015-10-07 | 海南灵康制药有限公司 | Novel industrial crystallizing technology for cefuroxime sodium |
WO2016201905A1 (en) * | 2015-06-15 | 2016-12-22 | 海南灵康制药有限公司 | New industrial crystallisation method for cefuroxime sodium and preparation thereof |
CN106565748A (en) * | 2016-09-30 | 2017-04-19 | 华北制药河北华民药业有限责任公司 | Preparation method for cefuroxime sodium and preparation thereof |
CN107652306A (en) * | 2017-10-24 | 2018-02-02 | 北京红太阳药业有限公司 | A kind of Cefuroxime Sodium crystal-form compound |
CN107652306B (en) * | 2017-10-24 | 2021-02-09 | 北京红太阳药业有限公司 | Cefuroxime sodium crystal compound |
CN108066338A (en) * | 2017-12-26 | 2018-05-25 | 金华智济药物科技合伙企业(有限合伙) | New antibiotic composition when prevention and treatment aerobic bacteria and anaerobic bacteria mixed infection and preparation method thereof |
CN108440568A (en) * | 2018-04-11 | 2018-08-24 | 广东立国制药有限公司 | A kind of preparation method of descarbamoyl cefuroxime |
CN109851627A (en) * | 2018-12-21 | 2019-06-07 | 广州白云山天心制药股份有限公司 | A kind of preparation method of Cefuroxime Sodium crystal-form compound |
CN109851627B (en) * | 2018-12-21 | 2022-04-12 | 广州白云山天心制药股份有限公司 | Preparation method of cefuroxime sodium crystal compound |
WO2023050596A1 (en) * | 2021-09-30 | 2023-04-06 | 海南海灵化学制药有限公司 | Process for preparing cefuroxime sodium for injection |
CN114292282A (en) * | 2021-12-09 | 2022-04-08 | 山东金特安全科技有限公司 | Method for synthesizing cefuroxime sodium based on continuous flow reaction technology |
CN114618410A (en) * | 2022-03-03 | 2022-06-14 | 清华大学 | Method for dissolving D-7-ACA by using microreactor |
CN115650995A (en) * | 2022-10-18 | 2023-01-31 | 浙江东盈药业有限公司 | Preparation method of cefuroxime sodium |
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Publication number | Publication date |
---|---|
CN100564382C (en) | 2009-12-02 |
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Effective date of registration: 20120203 Address after: 19, building 9, building B, Fortune Tower, No. 401121, Honghu East Road, Chongqing, Yubei District Patentee after: PKUCare Southwest Synthetic Pharmaceutical Corp., Ltd. Address before: 19, building 9, building B, Fortune Tower, No. 401121, Honghu East Road, Chongqing, Yubei District Co-patentee before: PKU International Healthcare Group Co., Ltd. Patentee before: PKUCare Southwest Synthetic Pharmaceutical Corp., Ltd. |
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Address after: 19, building 9, building B, Fortune Tower, No. 401121, Honghu East Road, Chongqing, Yubei District Patentee after: PKU HEALTHCARE CORP., LTD. Address before: 19, building 9, building B, Fortune Tower, No. 401121, Honghu East Road, Chongqing, Yubei District Patentee before: PKUCare Southwest Synthetic Pharmaceutical Corp., Ltd. |
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