CN101032561B - Chinese traditional medicine composition to be taken orally for curing hepatocirrhosis - Google Patents

Chinese traditional medicine composition to be taken orally for curing hepatocirrhosis Download PDF

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CN101032561B
CN101032561B CN2007100141438A CN200710014143A CN101032561B CN 101032561 B CN101032561 B CN 101032561B CN 2007100141438 A CN2007100141438 A CN 2007100141438A CN 200710014143 A CN200710014143 A CN 200710014143A CN 101032561 B CN101032561 B CN 101032561B
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medicine composition
radix
chinese medicine
liver
orally
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CN101032561A (en
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李庆彦
李庆方
柴霞
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Chai Xia
Li Qingfang
Li Qingyan
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Abstract

The present invention discloses one kind of oral Chinese medicine composition for treating hepatic cirrhosis, and belongs to the field of Chinese medicine technology. The Chinese medicine composition is prepared with 11 kinds of Chinese medicinal materials, including red sage, aweto, tuckahoe, forsythia, bupleurum root, etc in certain weight proportion, and through decocting. It has cheap material, easy preparation and no any toxic side effect.

Description

A kind of Chinese medicine composition of orally for curing hepatocirrhosis
Technical field
The present invention relates to a kind of Chinese medicine composition of orally for curing hepatocirrhosis.Be the Chinese medicine composition of the liver cirrhosis that causes of a kind of orally taken for curing a variety of causes specifically, belong to the field of Chinese medicines.
Background technology
Liver cirrhosis is a hepatitis interstitialis chronica, the formation of liver cirrhosis is because for a long time under harmful factors (as ethanol, hepatitis virus, Developmental and Metabolic Disorder) effect, hepatic necrosis, degeneration and inflammatory reaction, thereby stimulate the liver sternzellen, the Fibrotic material of a lot of formation of secretion, in the course of time, liver develops to liver cirrhosis from fibrosis.It is a kind of common chronic disease of clinical manifestation.Liver cirrhosis can be divided into compensatory cirrhosis and decompensated liver cirrhosis by course of disease development.
Liver cirrhosis is by causing that reason can be divided into: 1, the liver cirrhosis that causes of viral hepatitis, be liver cirrhosis after the viral hepatitis; 2, alcoholic cirrhosis; 3, parasitic liver cirrhosis; 4, biliary cirrhosis; 5, drug intoxication liver cirrhosis; 6, metabolic liver cirrhosis; 7, congestive cirrhosis (chronic heart failure) 8, nutritional cirrhosis; 9, congenital syphilis liver cirrhosis; 10, agnogenic liver cirrhosis.
The therapeutic goal of liver cirrhosis: by therapy of combining Chinese and Western medicine and the positive partner treatment of patient; strengthen maintenance; delay and reduce liver function and lose compensatory, protection and recover liver function; adjust albumen ratio; blocking-up and reverse hepatic fibrosis, liver cirrhosis prevent the appearance of liver failure and hepatocarcinoma, improve life quality; prolong the patient and receive a mandate, reduce case fatality rate.
Domestic and international state-of-the-art treatment means is at present: (1) combination of Chinese and Western medicine protects the liver, antiviral therapy (2) liver value of moving (3) splenectomy (4) spleen is got involved (5) artificial liver etc.
More than several treatment meanss have operative therapy expense costliness, side effect is big, the deficiency of late result difference.
Summary of the invention
The objective of the invention is to overcome the shortcoming of the big and Operation Fee costliness of the side effect of above-mentioned treatment liver cirrhosis, and a kind of Chinese medicine composition of orally for curing hepatocirrhosis is provided, it all selects natural Chinese medicinal herb for use, the therapeutic effect of raising liver cirrhosis.
Technical scheme of the present invention is: the Chinese medicine composition of this kind orally for curing hepatocirrhosis, it is characterized in that, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 10~20, Cordyceps 8~15, Poria 12~25, Fructus Forsythiae 8~20, Radix Bupleuri 5~9, Flos Carthami 3~9, Radix Notoginseng 10~20, Semen Persicae 8~15, Radix Glycyrrhizae 5~8, Carapax Trionycis (processed) 25~30 and Eupolyphaga Seu Steleophaga 2~5 by following weight portion.
Further technical scheme of the present invention is: the Chinese medicine composition of this kind orally for curing hepatocirrhosis, it is characterized in that, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 15, Cordyceps 10, Poria 10, Fructus Forsythiae 15, Radix Bupleuri 6, Flos Carthami 5, Radix Notoginseng 15, Semen Persicae 10, Radix Glycyrrhizae 6, Carapax Trionycis (processed) 27 and Eupolyphaga Seu Steleophaga 3 by following weight portion.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, then the Eupolyphaga Seu Steleophaga oven dry is ground into 100 order medicated powder.Add 600 milliliters in water in pot, go into Carapax Trionycis (processed) and be decocted first half an hour, each medicine of Radix Salviae Miltiorrhizae, Cordyceps, Poria, Fructus Forsythiae, Radix Bupleuri, Flos Carthami, Radix Notoginseng, Semen Persicae and Radix Glycyrrhizae of receiving again continues to fry in shallow oil half an hour, and is oral towards the Eupolyphaga Seu Steleophaga end with the gained decoction.Each potion of morning and evening.
Pharmacological action:
Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae has many-sided pharmacological action, as microcirculation improvement obstacle, change hemorheology situation, anticoagulant, antiinflammatory, anoxia enduring, raising immunologic function etc.Be applicable to that qi depression to blood stasis has the patient of heat in blood (mainly show as liver cirrhosis, splenomegaly, have low grade fever, agitation, insomnia, hypochondriac pain, carbuncle sore tumefacting virus etc. concurrently) concurrently.
Cordyceps: the major function of Cordyceps is tonifying deficiency, beneficial vital essence, is suitable for various deficient syndrome patients.
Poria: major function is eliminating dampness and diuresis, strengthening the spleen stomach function regulating, is suitable for deficiency-weakness of spleen-QI, ascites, the bullate patient of limb (show as edema distension, dysuria, have loose bowels, cough, insomnia etc.).
Fructus Forsythiae: heat clearing away, detoxifcation, eliminating stagnation, detumescence.Control warm, erysipelas, macule, the carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction; Laryngopharynx swelling and pain, rubella.
Radix Bupleuri: major function is dispersing the stagnated live-QI to relieve the stagnation of QI, separates yang invigorating in the harmony in the exterior, is suitable for stagnation of liver-QI with deficiency of the spleen class patient (show as distension after low grade fever, distending pain in the chest and hypochondrium, the food, feel sick, stomachache etc.).
Flos Carthami: be used for the obvious person of blood stasis sign, cure mainly blood stasis and have a pain, carbuncle, injury from falling down.
Radix Notoginseng: the effect hemostasia and dissipation blood stasis is used for liver cirrhosis patient and epistaxis, gingival hemorrhage, hematemesis, the person of having blood in stool occur.
Semen Persicae: the traditional Chinese medical science thinks that the major function of Semen Persicae is a blood stasis removing and clots absorbing, is applicable to that blood stasis sign is obvious, with patients such as dryness of the intestine constipation, purplish tongue, darkish complexion, hepatic region twinge, abdominal cavity infections.
Radix Glycyrrhizae: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Control weakness of the spleen and stomach, lack of appetite, the stomachache loose stool, the overstrain heating, the consumptive lung disease cough, cardiopalmus is fainted from fear; Give birth to usefulness, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
Carapax Trionycis (processed): support bright heat clearing away, suppressing the hyperactive liver to relieve the wind syndrome, hard masses softening and resolving.Control the consumptive fever hectic fever due to YIN-deficiency, stirring of wind due to deficiency of YIN, malaria with general debility malaria with splenomegaly, lump in the abdomen mass beside the umbilicus, amenorrhea menometrorrhagia, pediatric epilepsy scared.
Eupolyphaga Seu Steleophaga: by expectorant, removing mass, collateral dredging, reason is hindered.Control lump in the abdomen, amenorrhea due to stagnation of blood, postnatal blood stasis stomachache, traumatic injury, swollen and rigid tongue, congenital deformity of the tongue.
After the present invention mixed said medicine, its drug effect synergism in the liver cirrhosis therapeutic process, had been obtained unexpected remarkable result.The Chinese medicine composition of this kind orally for curing hepatocirrhosis is all selected natural Chinese medicinal herb for use, and raw material is cheap and easy to get, and preparation is convenient, and without any side effects.
Model case:
Example one: Song, the man, found liver cirrhosis in 2000, at examination in hospital, liver function AST/ALT:71/92u/l, Tbil/Dbil:88.6/46.3umol/L, A/G 29/45g/L, blood ammonia: 87.3umol/L, the Chinese medicine composition of oral this kind orally for curing hepatocirrhosis, the state of an illness took a turn for the better gradually in the 2nd day, continued to take and consolidated curative effect, and liver function recovery is normal after three courses of treatment
Example two: huge so-and-so, woman, 39 years old.The patient finds liver cirrhosis calendar year 2001, and the examination in hospital result shows that liver function is undesired: glutamate pyruvate transaminase 136u/L, and hepatic fibrosis index obviously increases, and B ultrasonic shows: liver cirrhosis, splenomegaly.Be diagnosed as: " hepatitis cirrhosis third type active stage ".Give treatments such as Chinese medicine composition with this kind orally for curing hepatocirrhosis protects the liver, antiviral, fibrosis.Liver power recovery is normal after one week, and hepatitis C virus does not duplicate after March, HCV-RNA Ocp/ml, and hepatic fibrosis index is normal, and B ultrasonic shows the spleen retraction after half a year, and stable disease reaches clinical cure substantially.
Example three: Dong so-and-so, the man, it is weak abdominal distention to occur in 1987, abnormal liver function is found in the county hospital inspection, be interrupted over 10 years and take Chinese medicine, the symptom fashion time difference, 11 days tired sxs of cause also hypomnesis occurs, obnubilation, delirium is multi-lingual, and outpatient service is looked into: AST:96, ALT138, TDil83.4, DBil57.2, A/G:27/46, B ultrasonic: liver cirrhosis, ascites, air spots, portal vein 1.5cm, the real light 0.73cm of gallbladder is double-deck, the thick 4.7cm of spleen.Give the traditional Chinese medicine composition for treating with this kind orally for curing hepatocirrhosis, the check liver function is normal fully after 22 days, and albumen is inverted and is obtained correcting, and ascites disappears, and portal vein attenuates, and it is normal that spleen and spleen V recover.
Example four: high so-and-so, man, 31 years old.Pathological examination before the treatment: the lobules of liver structure disturbance, pseudolobuli forms.Diagnosis: liver cirrhosis.Before the treatment: the hepatocyte edema, the organizational structure disorder, and see proliferation of fibrous tissue, and the portal area lymphocytic infiltration, visible pseudolobuli forms.Give traditional Chinese medicine composition for treating with this kind orally for curing hepatocirrhosis after 9 months, the treatment back: the hepatocyte edema absorbs, and inflammation is clearly better, and fibrous tissue reduces, and pseudolobuli disappears.
The specific embodiment
Example one: a kind of Chinese medicine composition of orally for curing hepatocirrhosis, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 10, Cordyceps 8, Poria 12, Fructus Forsythiae 8~20, Radix Bupleuri 5, Flos Carthami 3, Radix Notoginseng 10, Semen Persicae 8, Radix Glycyrrhizae 5, Carapax Trionycis (processed) 25, Eupolyphaga Seu Steleophaga 2 by following weight portion.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, with the Eupolyphaga Seu Steleophaga oven dry, be ground into 80 order medicated powder then.Add 500 milliliters in water, go into Carapax Trionycis (processed) and be decocted first half an hour, receiving Radix Salviae Miltiorrhizae, Cordyceps, Poria, Fructus Forsythiae, Radix Bupleuri, Flos Carthami, Radix Notoginseng, Semen Persicae and Radix Glycyrrhizae again continues to fry in shallow oil half an hour, oral towards the Eupolyphaga Seu Steleophaga end with the gained decoction.Each potion of morning and evening.
Example two: a kind of Chinese medicine composition of orally for curing hepatocirrhosis, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 20, Cordyceps 15, Poria 25, Fructus Forsythiae 20, Radix Bupleuri 9, Flos Carthami 9, Radix Notoginseng 20, Semen Persicae 15, Radix Glycyrrhizae 8, Carapax Trionycis (processed) 30, Eupolyphaga Seu Steleophaga 5 by following weight portion.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, with the Eupolyphaga Seu Steleophaga oven dry, be ground into 120 order medicated powder then.Add 1000 milliliters in water, go into Carapax Trionycis (processed with vinegar) and be decocted first half an hour, receiving Radix Salviae Miltiorrhizae, Cordyceps, Poria, Fructus Forsythiae, Radix Bupleuri, Flos Carthami, Radix Notoginseng, Semen Persicae and Radix Glycyrrhizae again continues to fry in shallow oil half an hour, oral towards the Eupolyphaga Seu Steleophaga end with the gained decoction.Each potion of morning and evening.
Example three: a kind of Chinese medicine composition of orally for curing hepatocirrhosis, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 15, Cordyceps 10, Poria 15, Fructus Forsythiae 15, Radix Bupleuri 6, Flos Carthami 5, Radix Notoginseng 14, Semen Persicae 10, Radix Glycyrrhizae 6, Carapax Trionycis (processed) 26, Eupolyphaga Seu Steleophaga 3 by following weight portion.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, with the Eupolyphaga Seu Steleophaga oven dry, be ground into 120 order medicated powder then.Add 800 milliliters in water, go into Carapax Trionycis (processed with vinegar) and be decocted first half an hour, receiving Radix Salviae Miltiorrhizae, Cordyceps, Poria, Fructus Forsythiae, Radix Bupleuri, Flos Carthami, Radix Notoginseng, Semen Persicae and Radix Glycyrrhizae again continues to fry in shallow oil half an hour, oral towards the Eupolyphaga Seu Steleophaga end with the gained decoction.Each potion of morning and evening.
Example four: a kind of Chinese medicine composition of orally for curing hepatocirrhosis, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 15, Cordyceps 10, Poria 10, Fructus Forsythiae 15, Radix Bupleuri 6, Flos Carthami 5, Radix Notoginseng 15, Semen Persicae 10, Radix Glycyrrhizae 6, Carapax Trionycis (processed) 27, Eupolyphaga Seu Steleophaga 3 by following weight portion.
During compounding pharmaceutical, the said medicine impurities in raw materials is removed, with the Eupolyphaga Seu Steleophaga oven dry, be ground into 100 order medicated powder then.Add 600 milliliters in water, go into Carapax Trionycis (processed with vinegar) and be decocted first half an hour, receiving Radix Salviae Miltiorrhizae, Cordyceps, Poria, Fructus Forsythiae, Radix Bupleuri, Flos Carthami, Radix Notoginseng, Semen Persicae and Radix Glycyrrhizae again continues to fry in shallow oil half an hour, oral towards the Eupolyphaga Seu Steleophaga end with the gained decoction.Each potion of morning and evening.

Claims (1)

1. the Chinese medicine composition of an orally for curing hepatocirrhosis, it is characterized in that, make the raw materials of effective components medicine and be: Radix Salviae Miltiorrhizae 10~20, Cordyceps 8~15, Poria 12~25, Fructus Forsythiae 8~20, Radix Bupleuri 5~9, Flos Carthami 3~9, Radix Notoginseng 10~20, Semen Persicae 8~15, Radix Glycyrrhizae 5~8, Carapax Trionycis (processed) 25~30 and Eupolyphaga Seu Steleophaga 2~5 by following weight portion.
CN2007100141438A 2007-04-04 2007-04-04 Chinese traditional medicine composition to be taken orally for curing hepatocirrhosis Expired - Fee Related CN101032561B (en)

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CN109248303A (en) * 2018-11-22 2019-01-22 南京市栖霞区医院 A kind of Chinese medicine composition of hyperbilirubinemia of newborn

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1287858A (en) * 1999-09-15 2001-03-21 姚同配 Traditional Chinese medicinal composition for treating hepatitis and its prepn. method
CN1453014A (en) * 2002-12-31 2003-11-05 张立中 Chinese medicine prepn for preventing fibrillated liver and treating hepatocirrhosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1287858A (en) * 1999-09-15 2001-03-21 姚同配 Traditional Chinese medicinal composition for treating hepatitis and its prepn. method
CN1453014A (en) * 2002-12-31 2003-11-05 张立中 Chinese medicine prepn for preventing fibrillated liver and treating hepatocirrhosis

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