CN101015300A - Silver-containing antibacterial agent - Google Patents
Silver-containing antibacterial agent Download PDFInfo
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- CN101015300A CN101015300A CN 200610054622 CN200610054622A CN101015300A CN 101015300 A CN101015300 A CN 101015300A CN 200610054622 CN200610054622 CN 200610054622 CN 200610054622 A CN200610054622 A CN 200610054622A CN 101015300 A CN101015300 A CN 101015300A
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- silver
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Abstract
The invention relates to a silver-containing antibacterial agent, especially an antibacterial agent used for antibiotic fiber processing. It comprises soluble argentic salt and quaternary ammonium salt, the silver content is high and the antibiotic ability is strong. The color change during argentic salt utilization can be avoided because of the composite antibiotic function of silver ion and quaternary ammonium salt and the property of strong association with fiber. The antibacterial agent is characterized by simple and easy preparation and process, low cost, short production cycle and feasibility of large- scale production.
Description
Technical field
The present invention relates to a kind of silver-containing antibacterial agent.
Background technology
Anti-biotic material refers to self to have killing or suppresses a class new function material of growth of microorganism function, there are many materials itself just to have the function of good sterilization and inhibition growth of microorganism at occurring in nature, as are partly with organic antibacterial agent, some inorganic metal materials and antibacterial agent, part mineral and the natural materials of specific group.But at present anti-biotic material more is meant by adding certain antibacterial material (being called antibacterial agent) thereby makes material have a class new function material that suppresses or kill its surface bacteria ability.Antibiotic plastic, anti-bacterial fibre, anti-bacteria ceramic all appear on the market, are applied to each field.
Antibacterial agent is divided into inorganic antiseptic, organic antibacterial agent, natural antibacterial agent and polymer antibacterial agent four classes substantially at present.Most widely used in the antibacterial agent is the inorganic antiseptic with good heat resistance, has a broad antifungal spectrum, term of validity length.Inorganic antiseptic mainly comprises carrier and antibiotic composition, and wherein the carrier load is held antibiotic composition, guarantees that active constituent is stable, have slow release simultaneously, antibiotic composition mainly is some metal ions, as silver, copper, zinc etc., though mercury, cadmium, lead have antibacterial ability, they are harmful; Copper, nickel, cobalt ions have color, will influence the attractive in appearance of product; Zinc has certain antibiotic property, but its antibacterial strength only is 1/1000 of a silver ion.But the sulfenyl of zymoprotein in the silver ion strong absorption bacterium, and combination rapidly, a tree name is measured, and when containing silver ion content in the water and reaching 0.05mg/L, just can kill Escherichia coli etc. fully and breed bacterium, and can keep reaching no new culture propagation in 90 days.Silver is below the 0.005*10-6 to the safety value of human body, and silver ion is limited the quantity of and is 0.05mg/L in the drinking-water.Therefore, silver ion antimicrobial agent occupies leading position in inorganic antiseptic, and the commercial overwhelming majority also is a silver-series antibacterial agent on the market.Silver is that anti-biotic material has the aqueous solution of soluble silver salt such as silver nitrate just to be used for neonatal eye sterilization at present, also be used for the treatment of canker sore, but soluble silver salt runs off easily and can't produce long-term antibacterial action; Microsolubility or slightly solubility silver salt such as silver sulfate, silver orthophosphate, silver halide, organic acid silver etc., this class microsolubility or slightly solubility silver salt see that light is easy to change, application is very limited; The carrying silver ion antibacterial agent, this class antibacterial agent has carrying silver ion hydroxyapatite, carrying silver ion imvite, carrying silver ion phosphate, carrying silver ion medical stone, carrying silver ion oxide such as carrying silver ion silica, carrying silver ion titanium dioxide etc., this class antibacterial agent silver content is low, complicated process of preparation, the cost height is applied to particularly processing difficulties during native fiber of fibre, is mainly used in fields such as resistant to elevated temperatures pottery and synthetic fibers and coating, plastics at present; Organic silver such as flamazine, protargin and amino acid silver, this class antibacterial agent is variable color easily also, generally is used for medicine; Nano Silver and carrying nano silver antibacterial agent; this class antibacterial agent is silver ion to be prepared into nano level silver-colored simple substance particle by chemical reaction or to be adsorbed on nano level silver-colored simple substance on the carrier; this class antibacterial agent is because be to use Nano Silver, thereby color is generally arranged, and the scope of application is restricted.
Summary of the invention
The purpose of this invention is to provide a kind of silver-containing antibacterial agent, particularly a kind of silver-containing antibacterial agent that is used for the antibiotic processing of fiber, this antibacterial agent is mixed by soluble silver salt and quaternary ammonium salt, the silver content height of this antibacterial agent, antibiotic property is strong, possess the composite antibiosis effect of silver ion and doped quaternary ammonium salt simultaneously, and combine characteristics such as firm, avoided the discoloration problem in the silver salt use again with fiber; Silver-containing antibacterial agent silver content height of the present invention, preparation technology is simple, cost is low, with short production cycle, can produce in enormous quantities.
Technical scheme of the present invention:
A kind of silver-containing antibacterial agent, it is characterized in that, silver-containing antibacterial agent, particularly a kind of silver-containing antibacterial agent that is used for the antibiotic processing of fiber, this antibacterial agent is mixed by soluble silver salt and quaternary ammonium salt, the silver content height of this antibacterial agent, antibiotic property is strong, possess the composite antibiosis effect of silver ion and doped quaternary ammonium salt simultaneously, and combine characteristics such as firm, avoided the discoloration problem in the silver salt use again with fiber; The preparation technology of this antibacterial agent is simple, cost is low, with short production cycle, can produce in enormous quantities.
A kind of preferred version, wherein said soluble silver salt are silver nitrate.
A kind of preferred version, wherein said quaternary ammonium salt are the quaternary ammonium halogen.
A kind of preferred version, wherein said quaternary ammonium halogen are quaternary ammonium bromine salt and quaternary ammonium salt compounded of iodine.
The silver nitrate solid can be dissolved in water, ethanol, acetone and the ammoniacal liquor.Consider from aspects such as dissolubility, production security and cost angles, generally make water as solvent; Owing to contain more chlorion in the light water, if make solvent, can generate water-fast silver chlorate colloidal solid after adding silver nitrate with light water, silver chlorate is to the ultraviolet light sensitivity, sees the silver atoms group that can generate the brown shape behind the light for a long time; Light water contains more calcium ion in addition, magnesium ion, and antibacterial agent is brought in the fibre finish liquid and increases hardness of water in the future, influences the softness of fiber, therefore preferably uses deionized water as solvent.Silver nitrate solvability in deionized water is bigger, does not generally need heating both can reach more than 400 grams per liters, and heating can obtain the salpeter solution of higher concentration, and room temperature is dissolved most economical convenience.Can use the stirring accelerate dissolution during silver nitrate dissolving.The container of the use during the silver nitrate dissolving can be selected stainless steel, glass, plastics, enamelled vessel and the utensil of inertia for use, can not use copper vessel and utensil.
Quaternary ammonium salt can be dissolved in water, ethanol, the acetone.Consider that from dissolubility, production security and cost angle ordinary priority is considered to make water as solvent.Because light water contains more calcium ion, magnesium ion has anti-effect short of money to quaternary ammonium salt, preferably uses deionized water as solvent.Quaternary ammonium salt solvability in deionized water generally can reach 10%, in order to increase the solvability of quaternary ammonium salt in solvent, and can be by quickening the quaternary ammonium salt dissolving.Heating-up temperature can select the non-crystallizable temperature of separating out of quaternary ammonium salt to room temperature.Also can use and stir accelerate dissolution, dissolution vessel can be selected stainless steel, glass, plastics, enamelled vessel and the utensil of inertia for use.
Stir down liquor argenti nitratis ophthalmicus and quaternary ammonium salt solution are mixed, on hybrid mode, liquor argenti nitratis ophthalmicus can be joined in the quaternary ammonium salt solution, also quaternary ammonium salt solution can be joined in the liquor argenti nitratis ophthalmicus, can also select for use liquor argenti nitratis ophthalmicus and quaternary ammonium salt solution to join simultaneously in the other container.From course of reaction control and production operation and cost consideration, preferably to select for use liquor argenti nitratis ophthalmicus is joined in the quaternary ammonium salt solution, stainless steel, glass, plastics, enamelled vessel and the utensil of selecting inertia for use are as the reaction container.In order fast liquor argenti nitratis ophthalmicus and quaternary ammonium salt solution to be mixed, preferably to use and stir.Select the non-crystallizable temperature of separating out of quaternary ammonium salt to the temperature range of room temperature optimal reaction temperature as preparation silver-containing antibacterial agent of the present invention.Because the reaction time can be very short, course of reaction can not need special thermostatic equipment.Material should continue to stir a period of time after adding end, so that material is fully reacted.Remove unnecessary raw material and byproduct of reaction if desired, can sedimentation separation or centrifugation, use the solvent wash precipitum then.Obtain solid contents such as powder if desired, just with the silver-containing antibacterial agent liquid dried.Drying can be nature airing, heating, drying, drying under reduced pressure, atomized drying.Baking temperature should not surpass the softening temperature and the decomposition temperature of silver-containing antibacterial agent.Baking temperature when generally speaking, the baking temperature during drying under reduced pressure is than constant pressure and dry is low.
Silver-containing antibacterial agent provided by the invention both possessed the strong antibiotic property, broad spectrum antibacterial of silver salt and to the human and environment safety, characteristic such as have no drug resistance, possess doped quaternary ammonium salt again and combine characteristics such as firm with fiber, and silver content height, avoid the discoloration problem of silver salt, can be used for colourless, white and light material.
Silver-containing antibacterial agent provided by the invention itself has high bactericidal activity value, can be used as antibacterials or antibacterials intermediate.
Quaternary ammonium salt and silver-containing antibacterial agent provided by the invention all have antibacterial action, but its antibiotic mechanism difference.Quaternary ammonium salt does not contain silver ion, does not possess the characteristic of silver antibacterial agent, and its antibiotic mechanism is to lean on the positive charge of self to adsorb electronegative bacterium, and the cell membrane of dissolution of bacteria makes bacterium death; Silver-containing antibacterial agent provided by the invention contains silver ion, and the silver ion that can dissociate out in the aqueous solution, silver ion combine with the sulfydryl of protein of bacteria and it lost activity and death.
Though quaternary ammonium salt has antibacterial action, because it is water-soluble strong, is easy to lose efficacy, thereby can only uses as disinfection sanitizer because of washing, the antibacterial finishing agent of general conduct weaving uses; Silver-containing antibacterial agent active ingredient provided by the invention is solid particle, and is water insoluble, and its antibacterial functions is lasting, and this is both remarkable differences on antibacterial functions.
Silver-containing antibacterial agent of the present invention and existing silver-series antibacterial agent compare, and the main distinction is the silver content height, sees the light nondiscolouring, and this can be used for colourless, white or light goods as white; Production technology is simple, and cost is low etc.; Because contain quaternary ammonium cation, therefore solved the problem that most of inorganic carrying silver antimicrobials can't effectively be adsorbed on fiber surface.
Beneficial effect
Silver-containing antibacterial agent provided by the invention, the silver content height, antibiotic property is strong, has both possessed doped quaternary ammonium salt and has combined characteristics such as firm with fiber, has avoided the discoloration problem in the silver salt use again.
The preparation technology of silver-containing antibacterial agent provided by the invention is simple, cost is low, with short production cycle, can produce in enormous quantities.
Embodiment
The present invention will be further described below by embodiment.
Embodiment 1
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; Doped quaternary ammonium salt softex kw 500 grams are joined 9.0 liters of deionized waters be heated to 40 ℃ of dissolvings, cool to 24 ℃ then, be prepared into B liquid, under stirring A liquid is joined in the B liquid, obtain silver-containing antibacterial agent T1.
Embodiment 2
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; Doped quaternary ammonium salt softex kw 1000 grams are joined 9 liters of deionized waters be heated to 50 ℃ of dissolvings, cool to 26 ℃ then, be prepared into B liquid, under stirring A liquid is joined in the B liquid, obtain silver-containing antibacterial agent T2.
Embodiment 3
Silver nitrate solid 160 gram joined in 1.0 liters of deionized waters dissolve, be prepared into A liquid; Octadecyl trimethylammonium bromide 552 grams are joined 9.0 liters of deionized waters be heated to 60 ℃ of dissolvings, cool to 30 ℃ then, be prepared into B liquid, under stirring A liquid is joined in the B liquid, obtain the graininess silver-containing antibacterial agent.Centrifugal filtration then with three washing leaching cakes of 15 liters of branches of deionized water, the centrifugal deionized water of sloughing, obtains white silver-containing antibacterial agent powder T3 after drying and the pulverizing.
Embodiment 4
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; Octadecyl trimethylammonium bromide 920 grams are joined 9 liters of deionized waters be heated to 60 ℃ of dissolvings, cool to 30 ℃ then, be prepared into B liquid, under stirring A liquid is joined in the B liquid, obtain silver-containing antibacterial agent T4.
Embodiment 5
Silver nitrate solid 160 gram joined in 1.0 liters of deionized waters dissolve, be prepared into A liquid; Eicosyl trimethyl ammonium iodide 659 grams are joined 19 liters of deionized waters be heated to 70 ℃ of dissolvings, cool to 65 ℃ then, be prepared into B liquid, stir down and A liquid is joined in the B liquid silver-containing antibacterial agent T5.
Embodiment 6
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; DTAB 578 grams are joined 9 liters of deionized waters be heated to 40 ℃ of dissolvings, cool to 6 ℃ then, be prepared into B liquid, stir down A liquid is joined in the B liquid, obtain graininess suspension, centrifugal filtration then is with three washing leaching cakes of 15 liters of branches of deionized water, the centrifugal deionized water of sloughing obtains silver-containing antibacterial agent powder T6 after drying and the pulverizing.
Embodiment 7
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; Dodecyl benzyl dimethyl ammonium chloride 958 grams are joined 9 liters of deionized waters be heated to 40 ℃ of dissolvings, cool to 6 ℃ then, be prepared into B liquid, under stirring A liquid is joined in the B liquid, obtain silver-containing antibacterial agent powder T7.
Embodiment 8
Silver nitrate solid 160 gram joined in 1.00 liters of deionized waters dissolve, be prepared into A liquid; Phenyl trimethyl ammonium iodide 495 grams are joined 9 liters of deionized waters be heated to 40 ℃ of dissolvings, cool to 20 ℃ then, be prepared into B liquid, stir down A liquid is joined in the B liquid, obtain graininess suspension, deionized water is sloughed in centrifugal filtration then, obtains silver-containing antibacterial agent powder T8 after drying and the pulverizing.
Claims (4)
1. silver-containing antibacterial agent, particularly a kind of silver-containing antibacterial agent that is used for the antibiotic processing of fiber, it is characterized in that, a kind of silver-containing antibacterial agent, this antibacterial agent is mixed by soluble silver salt and quaternary ammonium salt, the silver content height of this antibacterial agent, antibiotic property is strong, possess the composite antibiosis effect of silver ion and doped quaternary ammonium salt simultaneously, and combine characteristics such as firm, avoided the discoloration problem in the silver salt use again with fiber; The preparation method of this antibacterial agent, technology is simple, cost is low, with short production cycle, can produce in enormous quantities.。
2. silver-containing antibacterial agent according to claim 1 is characterized in that, wherein said soluble silver salt is a silver nitrate.
3. silver-containing antibacterial agent according to claim 1 is characterized in that, wherein said quaternary ammonium salt is the quaternary ammonium halogen.
4. silver-containing antibacterial agent according to claim 3 is characterized in that, wherein said quaternary ammonium halogen is quaternary ammonium bromine salt and quaternary ammonium salt compounded of iodine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610054622 CN101015300A (en) | 2006-02-07 | 2006-02-07 | Silver-containing antibacterial agent |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610054622 CN101015300A (en) | 2006-02-07 | 2006-02-07 | Silver-containing antibacterial agent |
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| CN101015300A true CN101015300A (en) | 2007-08-15 |
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| CN 200610054622 Pending CN101015300A (en) | 2006-02-07 | 2006-02-07 | Silver-containing antibacterial agent |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102726448A (en) * | 2012-07-03 | 2012-10-17 | 陕西师范大学 | Preparation method for antibacterial agent used for common surgery suture antibacterial agent used for common surgery suture |
| CN103938436A (en) * | 2014-04-04 | 2014-07-23 | 朱益锋 | Antibacterial finishing agent for sweater |
| CN104911847A (en) * | 2014-03-13 | 2015-09-16 | 张家港市金陵纺织有限公司 | Production technology of nano-silver antibiosis pure cotton yarn dyed fabric |
| CN105801734A (en) * | 2016-03-20 | 2016-07-27 | 北京化工大学 | Preparation method of quaternary ammonium salt polymer antibacterial agent and silver-loaded compound antibacterial agent thereof on basis of ATRP method |
| CN107050105A (en) * | 2017-02-24 | 2017-08-18 | 李忠泽 | A kind of antiseptic |
| CN109197899A (en) * | 2017-07-05 | 2019-01-15 | 北京农学院 | A kind of novel liquid nano silver antibacterial agent and its preparation method and application |
| CN113279144A (en) * | 2021-05-22 | 2021-08-20 | 冠和卫生用品有限公司 | Environment-friendly degradable non-woven fabric and preparation method thereof |
| CN113293512A (en) * | 2021-05-22 | 2021-08-24 | 冠和卫生用品有限公司 | Antibacterial skin-friendly non-woven fabric and preparation method thereof |
| CN113789585A (en) * | 2021-09-17 | 2021-12-14 | 兴源环境科技股份有限公司 | Antibacterial filter cloth for filter press and preparation method thereof |
| CN114874516A (en) * | 2022-04-01 | 2022-08-09 | 广东金发科技有限公司 | Antibacterial butyronitrile latex and preparation method and application thereof |
-
2006
- 2006-02-07 CN CN 200610054622 patent/CN101015300A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102726448A (en) * | 2012-07-03 | 2012-10-17 | 陕西师范大学 | Preparation method for antibacterial agent used for common surgery suture antibacterial agent used for common surgery suture |
| CN102726448B (en) * | 2012-07-03 | 2013-12-25 | 陕西师范大学 | Preparation method for antibacterial agent used for common surgery suture |
| CN104911847A (en) * | 2014-03-13 | 2015-09-16 | 张家港市金陵纺织有限公司 | Production technology of nano-silver antibiosis pure cotton yarn dyed fabric |
| CN103938436A (en) * | 2014-04-04 | 2014-07-23 | 朱益锋 | Antibacterial finishing agent for sweater |
| CN105801734A (en) * | 2016-03-20 | 2016-07-27 | 北京化工大学 | Preparation method of quaternary ammonium salt polymer antibacterial agent and silver-loaded compound antibacterial agent thereof on basis of ATRP method |
| CN107050105A (en) * | 2017-02-24 | 2017-08-18 | 李忠泽 | A kind of antiseptic |
| CN109197899A (en) * | 2017-07-05 | 2019-01-15 | 北京农学院 | A kind of novel liquid nano silver antibacterial agent and its preparation method and application |
| CN113279144A (en) * | 2021-05-22 | 2021-08-20 | 冠和卫生用品有限公司 | Environment-friendly degradable non-woven fabric and preparation method thereof |
| CN113293512A (en) * | 2021-05-22 | 2021-08-24 | 冠和卫生用品有限公司 | Antibacterial skin-friendly non-woven fabric and preparation method thereof |
| CN113789585A (en) * | 2021-09-17 | 2021-12-14 | 兴源环境科技股份有限公司 | Antibacterial filter cloth for filter press and preparation method thereof |
| CN114874516A (en) * | 2022-04-01 | 2022-08-09 | 广东金发科技有限公司 | Antibacterial butyronitrile latex and preparation method and application thereof |
| CN114874516B (en) * | 2022-04-01 | 2023-10-31 | 广东金发科技有限公司 | Antibacterial nitrile latex and preparation method and application thereof |
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