CN100557001C - A kind of nanometer composite rose-ambergris-sandalwood essence - Google Patents
A kind of nanometer composite rose-ambergris-sandalwood essence Download PDFInfo
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- CN100557001C CN100557001C CNB2006100294903A CN200610029490A CN100557001C CN 100557001 C CN100557001 C CN 100557001C CN B2006100294903 A CNB2006100294903 A CN B2006100294903A CN 200610029490 A CN200610029490 A CN 200610029490A CN 100557001 C CN100557001 C CN 100557001C
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Abstract
The invention discloses a kind of nanometer composite rose-ambergris-sandalwood essence, form: 0.4 (parts by weight) composite rose-ambergris-sandalwood essence, 0.15～0.4 (parts by weight) chitosan, 0.025～0.075 (parts by weight) tripoly phosphate sodium STPP, 0.225～0.7 (parts by weight) Glacial acetic acid, 1.0 (parts by weight) solubilizing agent, 200 (parts by weight) deionized water by following component.The nanometer composite rose-ambergris-sandalwood essence that the present invention makes, the solution clarification, the blue light phenomenon is obvious, but and this system stable existence.Behind laser particle analyzer and sem test, prepared nanometer composite rose-ambergris-sandalwood essence size distribution is more even, and the particulate size is about 100nm, and fragrance is stable.
Description
Technical field
The present invention relates to a kind of compound essence, more particularly relate to a kind of nanometer composite rose-ambergris-sandalwood essence by the preparation of Nano capsule technology.
Background technology
The notion of Nano capsule is proposed at the end of the seventies by people such as Narty the earliest, makes it obtain application in a lot of fields because of Nano capsule has peculiar property.Particularly in the capsular research of medicament nano, find that again it has good target and slow releasing function.Along with developing in depth and breadth of microcapsulary, the technology of multiple preparation Nano capsule has appearred, mainly comprise emulsion polymerization, interfacial polymerization, dry bath method, nanometer self-assembly method and electrostatic spray method etc. layer by layer.Because the Nano capsule particle is small, be easy to disperse and be suspended in to form colloidal solution in the water, as clear as crystal in appearance, have the peculiar property different with common microcapsule, therefore Nano capsule has been applied in medicine, makeup and plastic engineering material field, but is not seen in report as yet about document and the patent for preparing compound essence by the Nano capsule technology.After the essence Nano capsuleization, can improve the quality of essence, make product in the stability of fragrance, the more common essence in aspects such as slow-releasing and fragrance remaining time has certain advantage.
Summary of the invention
Technical problem to be solved by this invention provides a kind of nanometer composite rose-ambergris-sandalwood essence by the preparation of Nano capsule technology.
The technical solution used in the present invention: a kind of nanometer composite rose-ambergris-sandalwood essence, form by following component:
(0.4 parts by weight) composite rose-ambergris-sandalwood essence
～0.4 0.15 (parts by weight) chitosan
～0.075 0.025 (parts by weight) tripoly phosphate sodium STPP
～0.7 0.225 (parts by weight) Glacial acetic acid
(1.0 parts by weight) solubilizing agent
200 (parts by weight) deionized water
Wherein, described composite rose-ambergris-sandalwood essence is the Geraniol by 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and formed, and described solubilizing agent is selected from tween 20 or tween-80;
Described nanometer composite rose-ambergris-sandalwood essence is prepared from by the following step:
A. with the Geraniol of 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and is deployed into composite rose-ambergris-sandalwood essence according to above-mentioned parts by weight ratio;
B. in deionized water, add the solubilizing agent of 1.0 (parts by weight), add the composite rose-ambergris-sandalwood essence that step a makes again, obtain the composite rose-ambergris-sandalwood essence aqueous solution of transparent homogeneous after fully stirring;
C. the chitosan with 0.1～0.4 (parts by weight) is dissolved in the acetum that contains 0.225～0.7 (parts by weight) Glacial acetic acid, utilizes ultrasonic degradation 45～60 minutes, obtains transparent homogeneous solution;
D. the tripoly phosphate sodium STPP with 0.025～0.075 (parts by weight) is dissolved in the deionized water, until dissolving fully, adds the composite rose-ambergris-sandalwood essence aqueous solution that step b makes again, obtains another transparent homogeneous solution after fully stirring;
E. the solution that steps d is made is transferred in the acid buret, under the effect of magnetic agitation, with per 3 second 0.02ml～0.03ml speed splash in the solution that step c makes, after condensing of ion, reaction finishes and makes described nanometer composite rose-ambergris-sandalwood essence.
Beneficial effect of the present invention, the nanometer composite rose-ambergris-sandalwood essence that the present invention makes, the solution clarification, the blue light phenomenon is obvious, but and this system stable existence.Behind laser particle analyzer and sem test, prepared nanometer composite rose-ambergris-sandalwood essence size distribution is more even, and the particulate size is about 100nm, and fragrance is stable.
Embodiment
Below by embodiment the present invention is described in further detail, a kind of nanometer composite rose-ambergris-sandalwood essence, form by following component:
(0.4 parts by weight) composite rose-ambergris-sandalwood essence
～0.4 0.15 (parts by weight) chitosan
～0.075 0.025 (parts by weight) tripoly phosphate sodium STPP
～0.7 0.225 (parts by weight) Glacial acetic acid
(1.0 parts by weight) solubilizing agent
200 (parts by weight) deionized water
Wherein, described composite rose-ambergris-sandalwood essence is the Geraniol by 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and formed, and described solubilizing agent is selected from tween 20 or tween-80;
Described nanometer composite rose-ambergris-sandalwood essence is prepared from by the following step:
A. with the Geraniol of 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and is deployed into composite rose-ambergris-sandalwood essence according to above-mentioned parts by weight ratio;
B. in deionized water, add the solubilizing agent of 1.0 (parts by weight), add the composite rose-ambergris-sandalwood essence that step a makes again, obtain the composite rose-ambergris-sandalwood essence aqueous solution of transparent homogeneous after fully stirring;
C. the chitosan with 0.15～0.4 (parts by weight) is dissolved in the acetum that contains 0.225～0.7 (parts by weight) Glacial acetic acid, utilizes ultrasonic degradation 45～60 minutes, obtains transparent homogeneous solution;
D. the tripoly phosphate sodium STPP with 0.025～0.075 (parts by weight) is dissolved in the deionized water, until dissolving fully, adds the composite rose-ambergris-sandalwood essence aqueous solution that step b makes again, obtains another transparent homogeneous solution after fully stirring;
E. the tripoly phosphate sodium STPP system solution that steps d is made is transferred in the acid buret, under the effect of magnetic agitation, with per 3 second 0.02ml～0.03ml speed splash in the chitosan system solution that step c makes, after condensing of ion, reaction finishes and makes described nanometer composite rose-ambergris-sandalwood essence.
Embodiment 1 preparation nanometer composite rose-ambergris-sandalwood essence
In the 200ml beaker, add chitosan, 0.75g Glacial acetic acid and the 100g deionized water of 250mg, behind ultrasonic degradation, chitosan is dissolved in the Glacial acetic acid fully, obtain transparent and uniform solution; The tripoly phosphate sodium STPP of 25mg is dissolved in the 100g deionized water, adds the 1g tween 20 then as solubilizing agent, composite rose-ambergris-sandalwood essence 0.4g obtains transparent even tripoly phosphate sodium STPP system after the stirring fully; Subsequently this system is transferred in the acid buret, under the effect of magnetic agitation, splashes in the good chitosan solution of dissolving with the speed in per 3 seconds 1 (0.02ml-0.03ml).After condensing of ion, reaction finishes, and finds the solution clarification, light blue light is arranged, but the blue light phenomenon is not clearly.Illustrate and contain certain amount of nano capsule essence in this system, but proportion is less.After laser particle analyzer test, the result conforms to viewed experimental phenomena, and nano essence shared ratio in whole system is less.
Embodiment 2 preparation nanometer composite rose-ambergris-sandalwood essences
In the 200ml beaker, add chitosan, 0.75g Glacial acetic acid and the 100g deionized water of 250mg, behind ultrasonic degradation, chitosan is dissolved in the Glacial acetic acid fully, obtain transparent and uniform solution; The tripoly phosphate sodium STPP of 25mg is dissolved in the 100g deionized water, adds the 1g tween-80 then as solubilizing agent, composite rose-ambergris-sandalwood essence 0.4g obtains transparent even tripoly phosphate sodium STPP system after the stirring fully; Subsequently this system is transferred in the acid buret, under the effect of magnetic agitation, splashes in the good chitosan solution of dissolving with the speed in per 3 seconds 1 (0.02ml-0.03ml).After condensing of ion, reaction finishes, and finds the solution clarification, and the blue light phenomenon clearly and this system stable existence.After laser particle analyzer test, the result conforms to viewed experimental phenomena, and nano essence shared ratio in whole system is higher, illustrates that tween-80 is more suitable under this system as solubilizing agent.
Embodiment 3 preparation nanometer composite rose-ambergris-sandalwood essences
In the 200ml beaker, add chitosan, 0.6g Glacial acetic acid and the 100g deionized water of 400mg, behind ultrasonic degradation, chitosan is dissolved in the Glacial acetic acid fully, obtain transparent and uniform solution; The tripoly phosphate sodium STPP of 75mg is dissolved in the 100g deionized water, adds the 1g tween-80 then as solubilizing agent, composite rose-ambergris-sandalwood essence 0.4g obtains transparent even tripoly phosphate sodium STPP system after the stirring fully; Subsequently this system is transferred in the acid buret, under the effect of magnetic agitation, splashes in the good chitosan solution of dissolving with the speed in per 3 seconds 1 (0.02ml-0.03ml).After condensing of ion, reaction finishes, and finds the solution clarification, and the blue light phenomenon clearly.But place after for some time, just produce white floss in the solution, prove under this condition to form the nanometer micro essence, but this system instability.
Embodiment 4 preparation nanometer composite rose-ambergris-sandalwood essences
In the 200ml beaker, add chitosan, 0.45g Glacial acetic acid and the 100g deionized water of 300mg, behind ultrasonic degradation, chitosan is dissolved in the Glacial acetic acid fully, obtain transparent and uniform solution; The tripoly phosphate sodium STPP of 100mg is dissolved in the 100g deionized water, adds the 1g tween-80 then as solubilizing agent, composite rose-ambergris-sandalwood essence 0.4g obtains transparent even tripoly phosphate sodium STPP system after the stirring fully; Subsequently this system is transferred in the acid buret, under the effect of magnetic agitation, splashes in the good chitosan solution of dissolving with the speed in per 3 seconds 1 (0.02ml-0.03ml).After condensing of ion, reaction finishes, and finds the solution clarification, light blue light is arranged, but the blue light phenomenon is not clearly.Illustrate and contain certain amount of nano essence in this system, but proportion is less.
Embodiment 5 preparation nanometer composite rose-ambergris-sandalwood essences
In the 200ml beaker, add chitosan, 0.225g Glacial acetic acid and the 100g deionized water of 150mg, behind ultrasonic degradation, chitosan is dissolved in the Glacial acetic acid fully, obtain transparent and uniform solution; The tripoly phosphate sodium STPP of 20mg is dissolved in the 100g deionized water, adds the 1g tween-80 then as solubilizing agent, composite rose-ambergris-sandalwood essence 0.4g obtains transparent even tripoly phosphate sodium STPP system after the stirring fully; Subsequently this system is transferred in the acid buret, under the effect of magnetic agitation, splashes in the good chitosan solution of dissolving with the speed in per 3 seconds 1 (0.02ml-0.03ml).After condensing of ion, reaction finishes, and finds the solution clarification, and the blue light phenomenon clearly and this system stable existence.Behind laser particle analyzer and sem test, prepared nanometer composite rose-ambergris-sandalwood essence size distribution is more even, the particulate size about 100nm and fragrance stable.
Above said content only is the basic explanation of the present invention under conceiving, and according to any equivalent transformation that technical scheme of the present invention is done, all should belong to protection scope of the present invention.
Claims (1)
1. nanometer composite rose-ambergris-sandalwood essence, form by following component:
(0.4 parts by weight) composite rose-ambergris-sandalwood essence
～0.4 0.15 (parts by weight) chitosan
～0.075 0.025 (parts by weight) tripoly phosphate sodium STPP
～0.7 0.225 (parts by weight) Glacial acetic acid
(1.0 parts by weight) solubilizing agent
200 (parts by weight) deionized water
Wherein, described composite rose-ambergris-sandalwood essence is the Geraniol by 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and formed, and described solubilizing agent is selected from tween 20 or tween-80;
Described nanometer composite rose-ambergris-sandalwood essence is prepared from by the following step:
A. with the Geraniol of 5～8 (parts by weight), the geraniol of 10～15 (parts by weight), the vanirone of～1.5 0.5 (parts by weight), the piperonal of 2～3 (parts by weight), the phenylethyl alcohol of 20～30 (parts by weight), the santal 803 of 5～8 (parts by weight), the willow acid benzyl ester of 5～10 (parts by weight), the toluylic acid of～1 0.5 (parts by weight), the Jiale muskiness of 5～10 (parts by weight), the phantol of 5～8 (parts by weight), the phanteine of 3～4 (parts by weight), the santal 208 of 2～4 (parts by weight), the cedryl acetate of 3～5 (parts by weight), the telling of the labdanum balm and 2～4 (parts by weight) of 1～2 (parts by weight) received balm and is deployed into composite rose-ambergris-sandalwood essence according to above-mentioned parts by weight ratio;
B. in deionized water, add the solubilizing agent of 1.0 (parts by weight), add the composite rose-ambergris-sandalwood essence that step a makes again, obtain the composite rose-ambergris-sandalwood essence aqueous solution of transparent homogeneous after fully stirring;
C. the chitosan with 0.15～0.4 (parts by weight) is dissolved in the acetum that contains 0.225～0.7 (parts by weight) Glacial acetic acid, utilizes ultrasonic degradation 45～60 minutes, obtains transparent homogeneous solution;
D. the tripoly phosphate sodium STPP with 0.025～0.075 (parts by weight) is dissolved in the deionized water, until dissolving fully, adds the composite rose-ambergris-sandalwood essence aqueous solution that step b makes again, obtains another transparent homogeneous solution after fully stirring;
E. the solution that steps d is made is transferred in the acid buret, under the effect of magnetic agitation, with per 3 second 0.02ml～0.03ml speed splash in the solution that step c makes, after condensing of ion, reaction finishes and makes described nanometer composite rose-ambergris-sandalwood essence.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101142997B (en) * | 2007-10-29 | 2011-06-29 | 上海应用技术学院 | Method for preparing nanometer sweet orange essence |
| WO2013004003A1 (en) * | 2011-07-04 | 2013-01-10 | 丽华（泰国）香精有限公司 | Nano-flavor and preparation method thereof |
| CN103215130A (en) * | 2013-03-14 | 2013-07-24 | 天津市双马香精香料新技术有限公司 | Perfume essence with karanal added |
| CN106190570A (en) * | 2016-07-11 | 2016-12-07 | 中华全国供销合作总社杭州茶叶研究所 | A kind of spacetabs type plants essential oil and the preparation method of microcapsule powder thereof |
| CN112538400A (en) * | 2019-09-20 | 2021-03-23 | 广州汽车集团股份有限公司 | Vehicle-mounted fragrance and preparation method thereof |
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| 新的合成香料-"龙涎酯"的应用. 叶明福.香料香精化妆品，第4期. 1990 * |
| 玫瑰香精微胶囊粒径大小及分布的影响因素. 冯薇，葛艳蕊，王奎涛.第九届全国化学工艺学术年会论文集. 2005 * |
| 纳米微胶囊牛肉香精的制备技术研究. 肖作兵，章苏宁，叶琳，王进，李业成.香料香精化妆品，第6期. 2005 * |
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