CN100553476C - Be used for cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting and preparation method thereof - Google Patents

Be used for cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting and preparation method thereof Download PDF

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Publication number
CN100553476C
CN100553476C CNB2008100795268A CN200810079526A CN100553476C CN 100553476 C CN100553476 C CN 100553476C CN B2008100795268 A CNB2008100795268 A CN B2008100795268A CN 200810079526 A CN200810079526 A CN 200810079526A CN 100553476 C CN100553476 C CN 100553476C
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vitamin
cobastab
xylo
meat
poultry
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CN101366452A (en
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牛婵娟
韩旭东
王宏伟
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Huanan xinshuguang Feed Co., Ltd
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BAODING JIZHONG PHARMACEUTICAL Co Ltd
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Abstract

The invention discloses a kind of cysteamine hydrochlorate composite premixed material that is used for meat-poultry dynamiting and preparation method thereof, with the vitamin A of 10-30, the vitamin D of 3-10 3, the vitamin E of 3-10 and 50-800 the 1/5-4/5 of xylo-oligosaccharide mix, with the Cobastab of 0.50-1.50 2, 0.003-0.009 Cobastab 12, the folic acid of 0.50-1.0 and 50-800 the 1/10-1/5 of xylo-oligosaccharide mix, the glutamine of the solid emulsifier of the lysine of the methionine of the Mercaptamine inclusion compound of said mixture and 100-900,8-20,5-30,5-20,2-10 and remaining carrier xylo-oligosaccharide are mixed make again.The present invention can replenish poultry required vitamin and the amino acid of growth fast, can strengthen digesting and assimilating and utilizing of nutriments such as energy, nitrogen, calcium, phosphorus, improve carcass quality, improve lean meat percentage, strengthen human body immune function, improve resistance against diseases and anti-stress ability; Promote protein and fat digestion to absorb; Improve intestinal beneficial bacterium quantity, the material that has additional nutrients is digested and assimilated, and improves food conversion ratio.It can be used to improve the poultry production performance, can improve meat again.

Description

Be used for cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting and preparation method thereof
One, technical field:
The present invention relates to a kind of feed addictive that is used for meat-poultry dynamiting and preparation method thereof.
Two, background technology:
Along with the raising of intensive culture degree, support the daily ration that constantly drops into high-energy, high protein in the fowl production, in the hope of reaching the production performance of poultry the best.Yet factors such as pathological factors such as enteritis, diarrhoea, coccidia, non-pathological factor be easy to cause poultry produce in original trophic factors depart from feeding standard, cause that efficiency of feed utilization is low, production performance descends.Simultaneously, the physilogical characteristics of poultry determine it to the congenital incomplete absorption of some nutrient, and higher relatively to some vitamin requirement, therefore exogenous increase vitamin is to improve its human body performance, few sick, to improve the conversion ratio of feed, to improve meat quality is very necessary and crucial.People add the flavomycoin pre-mixing agent in the feed of being everlasting for this reason, but because the flavomycoin pre-mixing agent is an antibiotics, the medicine residue of its generation is unfavorable to the growth of poultry again, and influences the quality of poultry meat.How both to have improved the growth performance of poultry, and can improve the quality of poultry meat again, and the method that reduces raising breeding performonce fo animals such as its feedstuff-meat ratio is the problem that people were concerned about and studied always.
Three. summary of the invention:
Purpose of the present invention solves the above-mentioned problems in the prior art exactly, and a kind of poultry production performance that can be used to improve is provided, and can improve the cysteamine hydrochlorate composite premixed material that is used for meat-poultry dynamiting of meat again.
For finishing above-mentioned purpose, technical solution of the present invention is: a kind of cysteamine hydrochlorate composite premixed material that is used for meat-poultry dynamiting, it is made by following raw material: by weight calculating: the Mercaptamine hydroxyethyl-inclusion compound of 100-900, the solid emulsifier of 5-20, the glutamine of 2-10, the vitamin A of 10-30, the vitamin D of 3-10 3, the vitamin E of 3-10, the Cobastab of 0.50-1.50 2, 0.003-0.009 Cobastab 12, the folic acid of 0.50-1.0, the methionine of 8-20, the lysine of 5-30 and the carrier xylo-oligosaccharide of 50-800.
Above-mentioned described of the present inventionly make: by weight calculating: the Mercaptamine hydroxyethyl-inclusion compound of 150-600, the solid emulsifier of 7.5-15, the glutamine of 3-9, the vitamin A of 12.5-25, the vitamin D of 3-10 by following raw material 3, the vitamin E of 3-10, the Cobastab of 0.50-1.50 2, 0.003-0.009 Cobastab 12, the folic acid of 0.50-1.0, the methionine of 8-20, the lysine of 5-30 and the carrier xylo-oligosaccharide of 200-800.
Above-mentioned described solid emulsifier of the present invention is one or more mixtures in soybean lecithin, lignin hydrochlorate, the glycerin monostearate.
The preparation method that above-mentioned described the present invention is used for the cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting is: it may further comprise the steps:
(1) presses described formula ratio with vitamin A, vitamin D 3, vitamin E and 1/5-4/5 xylo-oligosaccharide to mix the back standby;
(2) press described formula ratio with Cobastab 2, Cobastab 12, folic acid and 1/10-1/5 xylo-oligosaccharide to mix the back standby;
(3) by described formula ratio Mercaptamine inclusion compound, methionine, lysine, solid emulsifier, glutamine, remaining carrier xylo-oligosaccharide and above-mentioned standby raw material are mixed.
Above-mentioned described Mercaptamine inclusion compound can be made by following method: take by weighing Mercaptamine, hydroxyethyl-in 1: 1 ratio; After hydroxyethyl-being added water-soluble the separating of 3 times of amounts, under the ultrasonic wave effect, slowly add the Mercaptamine that takes by weighing, after adding is finished, continue to use ultrasonic echography 15-25min; With behind the membrane filtration of liquid with 0.45 μ m, use the membrane filtration of 0.22 μ m more then, after the solution of gained is spray-dried, get Mercaptamine hydroxyethyl-inclusion compound white powder.
Because the present invention adopted such scheme, 1, vitamin A, vitamin D in the prescription 3, vitamin E, Cobastab 2, Cobastab 12, folic acid, methionine, lysine can replenish poultry required vitamin and the amino acid of growth fast, to reduce the diseases such as inferior health that high-energy, high protein feed cause.2, the Mercaptamine in the prescription can effectively be exhausted growth hormone release inhibiting hormone (SS), promote growth hormone (GH) secretion, various animals there are the growth promotion in various degree and the effect of improving health conditions, can strengthen digesting and assimilating and utilizing of nutriments such as energy, nitrogen, calcium, phosphorus, improve carcass quality, improve lean meat percentage, strengthen human body immune function, improve resistance against diseases and anti-stress ability.Promote growth hormone (GH) can also act on liver, promote the IGF secretion, thereby promote growth of animal, improve the body health level, reduce food consumption, and under stress situation, can block and cause the reduction of GH content and play anti-stress effect.Simultaneously, can improve the secretion of insulin, secretin, CCK, gastrin, thyroid hormone T3 and T4 etc., reach the poultry body is carried out whole physiological regulation and control.3, promote protein and fat digestion to absorb by the binomial regulating action.The one, compositions such as solid emulsifier and starch or protein interact, and improve the structure of nutriment and the anti-aging effect of rheological characteristic emulsifying agent, disperse protein molecule, and the contact area of increase and protease improves digestibility; The 2nd, improve oil and fatty acid molecule closely piling up of hydroxyl chain up and down, make in the more uniform dispersed oil of water, effectively promote the formation of chylomicron, strengthen the absorption and the utilization of fat or energy.4, glutamine is the main source of intestinal motive force, can increase intestinal villi length, improve intestinal beneficial bacterium quantity, and the material that has additional nutrients is digested and assimilated, and improves food conversion ratio.
The pre-mixing agent of product of the present invention was done following efficacy test:
1, the application study of cysteamine hydrochlorate composite premixed material of the present invention in daily ration of broiler:
This experimental applications cysteamine hydrochlorate composite premixed material, two kinds of additives of flavomycoin pre-mixing agent, 1200 AA fryer are carried out production performance and economic efficiency contrast, and experiment divides three groups: blank group, cysteamine hydrochlorate composite premixed material group, flavomycoin pre-mixing agent group.
Result of the test shows: the chicken that the cysteamine hydrochlorate composite premixed material group of searching for food is raised, daily gain is higher by 4.01% than flavomycoin pre-mixing agent group, and is higher by 6.17% than control group.Economic and Efficiency Analysis shows: the cysteamine hydrochlorate composite premixed material group is higher by 7.55% than flavomycoin pre-mixing agent group economic benefit, and is higher by 14.3% than blank group.
2, the application of cysteamine hydrochlorate composite premixed material on hen:
This experiment is divided into 2 groups at random with the three yellow hens that 3000 70 age in days body weight are about 790g, every group 1500 plumage, the control group fed basal diet, test group is fed and is added 1000g/ ton cysteamine hydrochlorate composite premixed material on the basal diet basis, the result shows that experimental group improves 14.93% than control group daily gain, and feedstuff-meat ratio reduces by 15.36%.
3, the application of cysteamine hydrochlorate composite premixed material on cherry paddy meat duck:
This experiment is divided into control group and experimental group at random with 8000 plumages, 11 age in days cherry paddy meat ducks, the control group fed basal diet, experimental group is added 1000g/ ton cysteamine hydrochlorate composite premixed material on the basal diet basis of feeding, the result shows that experimental group improves 9.12% than control group daily gain, and feedstuff-meat ratio descends 15.03%.
Four. the specific embodiment: the invention will be further described below in conjunction with the specific embodiment.
Embodiment 1: present embodiment is made by following raw material, by weight calculating: Mercaptamine hydroxyethyl-inclusion compound 100, soybean lecithin 15, glutamine 10, vitamin A 15, vitamin D 310, vitamin E 8, Cobastab 21.0, Cobastab 120.009, folic acid 0.50, methionine 8, lysine 20 and xylo-oligosaccharide 800.
1, by taking by weighing Mercaptamine, hydroxyethyl-at 1: 1, after hydroxyethyl-being added water-soluble the separating of 3 times of amounts, the ultrasonic Mercaptamine that takes by weighing that slowly adds down, continue ultrasonic 15-25min, with the membrane filtration of using 0.22 μ m behind the membrane filtration of 0.45 μ m again, after the solution of gained is spray-dried, get white powder, be Mercaptamine hydroxyethyl-inclusion compound.
2, with vitamin A, the vitamin D of above-mentioned described amount 3, that vitamin E and 10-50 carrier xylo-oligosaccharide mix the back is standby;
3, with the Cobastab of above-mentioned described amount 2, Cobastab 12, that folic acid and 10-50 carrier xylo-oligosaccharide mix the back is standby;
4, direct packaging promptly after standby raw material mixed with methionine, lysine, soybean lecithin, glutamine and the remaining carrier of preliminary treatment Mercaptamine inclusion compound and described amount with after just mixing.
Embodiment 2, and present embodiment is made by following raw material, by weight calculating: Mercaptamine hydroxyethyl-inclusion compound 200, lignin hydrochlorate 7.5, glutamine 9, vitamin A 10, vitamin D 35, vitamin E 5, Cobastab 20.75, Cobastab 120.0075, folic acid 0.90, methionine 12, lysine 15 and xylo-oligosaccharide 720.Its preparation method is with embodiment 1.
Embodiment 3, and present embodiment is made by following raw material, by weight calculating: Mercaptamine hydroxyethyl-inclusion compound 600, glycerin monostearate 20, glutamine 2, vitamin A 30, vitamin D 33, vitamin E 10, Cobastab 21.5, Cobastab 120.003, folic acid 1.0, methionine 20, lysine 30 and xylo-oligosaccharide 280.Its preparation method is with embodiment 1.
Embodiment 4, present embodiment is made by following raw material, by weight calculating: Mercaptamine hydroxyethyl-inclusion compound 900, soybean lecithin 2, lignin hydrochlorate 2, glycerin monostearate 1, glutamine 5, vitamin A 12.5, vitamin D 38, vitamin E 3, Cobastab 20.50, Cobastab 120.005, folic acid 0.7, methionine 16, lysine 5 and xylo-oligosaccharide 200.Its preparation method is with embodiment 1.
Embodiment 5, and present embodiment is made by following raw material, by weight calculating: Mercaptamine hydroxyethyl-inclusion compound 150, lignin hydrochlorate 9, glycerin monostearate 9, glutamine 3, vitamin A 25, vitamin D 36, vitamin E 9, Cobastab 21.20, Cobastab 120.006, folic acid 0.6, methionine 10, lysine 10 and xylo-oligosaccharide 50.Its preparation method is with embodiment 1.
Its Comparison of therapeutic is as follows
Test one: the effect of cysteamine hydrochlorate composite premixed material on fryer:
1 materials and methods
This test selects normotrophic AA commodity to mix 1200 of chick for male and female, is divided into three groups at random.Test group: every 1000kg feed adds cysteamine hydrochlorate composite premixed material 1kg.The medicine control group: every 1000kg feed adds flavomycoin pre-mixing agent 5g.Blank group: do not add any medicine or feed addictive.
2 testing indexs
2.1 survival rate: observe and write down chicken group's health status and dead number of elements, calculate chicken group's death rate and survival rate.
2.2 weightening finish: claim that at 0,14,35,42 ages in days the group of each experimental group chicken is heavy, calculate average daily gain, rate of body weight gain, and carry out statistical analysis.
2.3 feed conversion rate: the feed intake of chicken respectively organized in record, calculates feedstuff-meat ratio, and carry out statistical analysis.
2.4 economic benefit is calculated: calculate input and output, carry out the value-added performance analysis of fryer.
3 result of the tests and discussion
The application study of the cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting in daily ration of broiler, result of the test is as follows:
Chicken survival rate (%) Rate of body weight gain (%) Feedstuff-meat ratio Benefit relatively
Test group 96.75 106.17 1.96 114.3
The medicine control group 95.75 102.16 2.17 106.75
The blank group 95 100 2.36 100
Result of the test confirms that Mercaptamine compound premixing agent group, flavomycoin pre-mixing agent group all can be improved food conversion ratio, and promotes growth of meat chicken, but obvious with Mercaptamine compound premixing agent group effect.
Test two: the effect of cysteamine hydrochlorate composite premixed material on hen:
The three yellow hens that test selects 3000 70 age in days body weight to be about 790g are divided into 2 groups at random, every group 1500 plumage, and the control group fed basal diet, test group is fed and is added 1000g/ ton cysteamine hydrochlorate composite premixed material on the basal diet basis, and result of the test is as follows:
Project Experimental group Control group Improve (%)
Daily gain (g) 10.47 9.11 +14.93
Feedstuff-meat ratio 5.84 6.90 -15.36
Death rate (%) 0.4 1.2 -66.67
The result shows that experimental group improves 14.93% than control group daily gain, and feedstuff-meat ratio reduces by 15.36%, and dead and mortality descends 66.67%.
Experiment three: the effect of cysteamine hydrochlorate composite premixed material on cherry paddy meat duck:
8000 plumages, 11 age in days cherry paddy meat ducks are selected in test, are divided into control group and experimental group, the control group fed basal diet, and experimental group is added 1000g/ ton cysteamine hydrochlorate composite premixed material on the basal diet basis of feeding, and result of the test is as follows:
Project Experimental group Control group Improve (%)
Daily gain (g) 104.24 95.37 9.3
Feedstuff-meat ratio 2.18 2.56 -14.8
Death rate (%) 0.10 0.4 -75.0
The result shows that experimental group improves 9.3% than control group daily gain, and feedstuff-meat ratio descends 14.8%, and dead and mortality descends 75.0%.

Claims (3)

1, a kind of cysteamine hydrochlorate composite premixed material that is used for meat-poultry dynamiting, it is characterized in that: it is made by following raw material: by weight calculating the Mercaptamine hydroxyethyl-inclusion compound of 100-900, the solid emulsifier of 5-20, the glutamine of 2-10, the vitamin A of 10-30, the vitamin D of 3-10 3, the vitamin E of 3-10, the Cobastab of 0.50-1.50 2, 0.003-0.009 Cobastab 12, the folic acid of 0.50-1.0, the methionine of 8-20, the lysine of 5-30 and the carrier xylo-oligosaccharide of 50-800; Described Mercaptamine hydroxyethyl-inclusion compound can be made by following method: take by weighing Mercaptamine, hydroxyethyl-in 1: 1 ratio; After hydroxyethyl-being added water-soluble the separating of 3 times of amounts, under the ultrasonic wave effect, slowly add the Mercaptamine that takes by weighing, after adding is finished, continue to use ultrasonic echography 15-25min; With behind the membrane filtration of liquid with 0.45 μ m, use the membrane filtration of 0.22 μ m more then, after the solution of gained is spray-dried, the white powder that makes.
2, the cysteamine hydrochlorate composite premixed material that is used for meat-poultry dynamiting according to claim 1, it is characterized in that: it is made by following raw material: by weight calculating the Mercaptamine hydroxyethyl-inclusion compound of 150-600, the solid emulsifier of 7.5-15, the glutamine of 3-9, the vitamin A of 12.5-25, the vitamin D of 3-10 3, the vitamin E of 3-10, the Cobastab of 0.50-1.50 2, 0.003-0.009 Cobastab 12, the folic acid of 0.50-1.0, the methionine of 8-20, the lysine of 5-30 and the carrier xylo-oligosaccharide of 200-800.
3, a kind of preparation method that is used for the cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting as claimed in claim 1 or 2, it is characterized in that: it may further comprise the steps:
(1) presses described formula ratio with vitamin A, vitamin D 3, vitamin E and 1/5-4/5 xylo-oligosaccharide to mix the back standby;
(2) press described formula ratio with Cobastab 2, Cobastab 12, folic acid and 1/10-1/5 xylo-oligosaccharide to mix the back standby;
(3) by described formula ratio Mercaptamine hydroxyethyl-inclusion compound, methionine, lysine, solid emulsifier, glutamine, remaining carrier xylo-oligosaccharide and above-mentioned standby raw material are mixed.
CNB2008100795268A 2008-10-07 2008-10-07 Be used for cysteamine hydrochlorate composite premixed material of meat-poultry dynamiting and preparation method thereof Expired - Fee Related CN100553476C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104026350B (en) * 2013-05-08 2016-05-25 济南海华生物科技有限公司 Mercaptamine preparation and application thereof
CN108887478A (en) * 2018-06-06 2018-11-27 广东鹏汇生物科技有限公司 A kind of trophic function type feed addictive and preparation method thereof
CN108967735A (en) * 2018-10-11 2018-12-11 河北正合生物制药有限公司 A kind of feed addictive that can improve chicken intestinal institutional framework and growth performance
CN115349579A (en) * 2022-08-24 2022-11-18 石家庄正道动物药业有限公司 Birch oak essence for improving meat quality of meat poultry and extraction method and application thereof

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Effective date of registration: 20181213

Address after: 154400 Huanan County Economic Development Zone, Jiamusi City, Heilongjiang Province

Patentee after: Heilongjiang Deyucheng Industrial Co., Ltd.

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Patentee before: Baoding Jizhong Pharmaceutical Co., Ltd.

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