CN100544724C

CN100544724C - Hexamethylenamine is used for preparing the application that treatment prevents the medicament of furfur, scalp itching and hair loss

Info

Publication number: CN100544724C
Application number: CNB200610020110XA
Authority: CN
Inventors: 许多全
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-01-05
Filing date: 2006-01-05
Publication date: 2009-09-30
Anticipated expiration: 2026-01-05
Also published as: CN1994305A

Abstract

Hexamethylenamine is many at preparation treatment prevention dandruff, the application in the medicament of scalp pruritus, alopecia, hexamethylenamine is prepared into certain density solution is applied to the head affected part, it is to utilize the physicochemical properties of hexamethylenamine and have germ-resistant pharmacological action, at causing that the dandruff is many, the fungus of scalp pruritus sterilizes, suppress fungus breeding, scalp is no longer scratched where it itches, keep cortex health, ventilative, non-greasy, allow the more pleasant health of head.Utilize hexamethylenamine convergence, antisudorific pharmacological action, the sebaceous gland of convergence hypertrophy reduces the effect of sebum secretion and blood circulation promoting, has the cleaning stimulation for the hair pore that has come off, activates moving hair follicle and impels hair regeneration long.The convergence of crow tropine also makes the more firm life of hair on scalp, hair is come off naturally and disease comes off controlledly, effectively plays the effect of hair care additional issue.The aqueous solution of hexamethylenamine is alkalescence, and some composition such as oleic acid, linoleic acid, Squalene etc. make the sebum secretion thing be acid in the sebum secretion thing, and hexamethylenamine can decomposite formaldehyde in wrecked sour environment, can play the germ-resistant effect of deep layer, the acid-base value of skin of head, balancing human body endocrine, human body immunity improving power are regulated in neutralization, can make hair follicle quicken metabolism, promote hair growth.Be used to prepare medicament promptly become a kind ofly have that the Comprehensive Treatment dandruff is many, the medicament of scalp pruritus, hair alopecia symptom; Use it for be prepared into shampoo have that Comprehensive Treatment prevention dandruff is many, the shampoo of scalp pruritus, hair alopecia symptom effect; Use it for preparation Hair grooming perfume, promptly become have that prophylactic treatment prevention dandruff is many, the perfume of scalp pruritus, alopecia symptom effect.

Description

Hexamethylenamine is used for preparing the application that treatment prevents the medicament of furfur, scalp itching and hair loss

Affiliated technical field

The present invention uses the genus field of medicaments, relate to and be used for the treatment of many, the scalp pruritus of prevention dandruff, anti-loss and medicament that can the hair strengthening additional issue, be applied to prepare medical drug promptly become a kind ofly have that treatment prevents that dandruff is many, scalp pruritus, alopecia symptom and syndromic medicament thereof; Be applied to prepare the head shampoo have that treatment prevention dandruff is many, the shampoo of scalp pruritus or alopecia symptom; Be applied to prepare Hair grooming perfume, promptly become and have that prophylactic treatment prevention dandruff is many, the perfume of scalp pruritus alopecia symptom effect.

Background technology

The dandruff medically is being called " capitis pityriasis ", " head fat leaks disease ".Its performance can be divided into dryness dandruff and two kinds of forms of oiliness dandruff.Dry scalp is considered many looselys to be worth doing and is distributed on the scalp, often be the squama shape easily when sending out and come off when combing one's hair or grabbing to scratch one's head, and color mostly is white or canescence; The oiliness dandruff then more to adhere on the hair, has difficult drop-off with the faint yellow crumb form formula of oils and fats sample.The phenomenon nothing to be surprised at of the many and scalp pruritus of the dandruff, but when often coming off in a large number as the dandruff such as the snowflake, become a kind of skin of head disease quite influences attractive in appearancely, brings worry and misery to the people, has a strong impact on live and work.The dandruff is actually the sebum of supersecretion and filthy dust etc. and mixes, just become the dandruff after having done, though or sebum less but because of the horn cell paraplasm, also can become the dandruff, the vigorous people of brain overwork person and metabolism more is easy to generate the dandruff.

Alopecia or title alopecia are a kind of common hair diseases.Its kind is more, as congenital alopecia, posteriority alopecia, alopecia cicatrisata, alopecia areata and seborrheic alopecia etc.Have nearly 1/4th male suffer from male pattern alopecia in China, and white people's prevalence is higher, is almost 100%.Wherein modal is seborrheic alopecia, is more common in male adults, accounts for 95% of all hair loss patients of male, claims male pattern alopecia again.The greasy shape of polishing that is of the patient's hair that has; The dry gloss that lacks of the hair that also has often has a large amount of dandruffs, and often appearance is very itched, as long as grab with hands, hair will come off, and especially the performance spy is outstanding especially when hair washing, combing.Scalp is scratched where it itches can further stimulate sebaceous gland, make the sebaceous gland hypertrophy and secrete more scalp pomade, and when some composition such as oleic acid, linoleic acid, Squalene etc. are excessive in the sebum secretion thing to the toxic effect of hair follicle, can further cause fur to poison, wither, come off; With the passing of time, particularly chronic alopecia generalisata also can take place in the both sides frontal eminence.The speed and the scope of alopecia vary with each individual, and majority is made slow progress.The female patients alopecia is portion overhead mainly, and hair is the diffusivity rareness, and seborrheic alopecia is if untimely treatment will become permanent.This disease is having a strong impact on patient's quality of life such as emotion, work and study, employment, friend-making and social activity.The cause of disease of alopecia also imperfectly understands at present.It is generally acknowledged and heredity, endocrine function, infection focus, autoimmune function, Nervous and Mental Factors, and nutriture etc., certain relation is all arranged.

The common dandruff of head is many, scalp pruritus, hair seriously come off, the case of poliosis surge is a lot, method to its treatment is a lot, but be more common in function singleness, DeGrain, except more complete therapeutic scheme is arranged clinically, also there is not a kind of medicament light system to administer this class disease at present.To more complete clinically therapeutic scheme, but the therapeutic process complexity, treatment time is long, and is bigger to head injury, and medical expense higher (as: hair transplant); Equally, at present the function of head shampoo also is so, though the shampoo types of brand are many, effect is separately spoken very well, actual usefulness instability, not only not protecting of having act on injury effect on the contrary, real effective product is few of.General hair lotion and medicine all have toxic and side effects in various degree, make troubles to the patient, to such an extent as to bald head more and more is younger, juvenileization of hoary hair, this with much relations are arranged in that the effect of treatment this respect is ineffective at present.

Summary of the invention

At the limitation aspect present, scalp pruritus many, the anti-loss therapy in the treatment prevention dandruff, the application of medicament of the present invention can be treated many, the scalp pruritus, anti-loss of the prevention dandruff fast, play the effect of hair strengthening additional issue simultaneously, the comprehensive above-mentioned disease of treatment of medicament energy with the hexamethylenamine preparation, both easy and evident in efficacy, from physiology, psychology, the economic patient's pressure that reduces, can treat many, the scalp pruritus, effectively anti-loss of the prevention dandruff fast, promote natural on-off cycles of hair growth, also the image of a health of patient.

The technical solution adopted in the present invention

Be prepared into certain density solution with hexamethylenamine and be applied to the head affected part, utilize the distinctive bactericidal action of Wu Luotuo, the head part is carried out cleaning-nursing.The sterilizing function of hexamethylenamine can effectively be removed the living environment of the fungus that causes the dandruff, makes not excessive multiplication and the dandruff of producing is in the salubrious environment of health the scalp layer, away from pollution of fungus.

Scalp pruritus mainly is that hexamethylenamine can suppress fungus breeding, and scalp is no longer scratched where it itches because of the fungus excessive multiplication causes the head discomfort even seriously to dermatitis, keep the cortex health, ventilative, easily, non-greasy, allow the more pleasant health of head.

Hair excessively comes off and can cause various forms of bald heads, and the attack of various antibacterials to hair and scalp can be effectively resisted in the bactericidal action of skin hexamethylenamine, makes the hair survival and development that a clean salubrious environment be arranged; The convergence of hexamethylenamine has the sebaceous gland that restrains hypertrophy, reduces the effect of sebum secretion and blood circulation promoting, has the cleaning stimulation for the hair pore that has come off, activates hair follicle and impels hair regeneration long.The convergence of hexamethylenamine also makes more firm being grown on the scalp of hair, even have under the situation of external force effect at hair washing, head massage, Hair setting etc., hair is difficult drop-off also, hair comes off naturally and disease comes off controlled, New Development energy healthy growth, hair has also just increased naturally, effectively plays the effect of hair care additional issue.

Hexamethylenamine is soluble in water; its aqueous solution is alkalescence; and some composition such as oleic acid, linoleic acid, Squalene etc. make the sebum secretion thing be acid in the sebum secretion thing, and hexamethylenamine can decomposite formaldehyde in wrecked sour environment, can play the germ-resistant effect of deep layer; the acid-base value of skin of head is regulated in neutralization; degree of depth protection head cortex health, human body immunity improving power can make hair follicle quicken metabolism; the balancing human body endocrine makes the hair self-sow.

The specific embodiment

Scratch where it itches for the treatment dandruff and scalp, after hair washing treats that head is done, droplet be coated on the scalp with the solution number of hexamethylenamine, smear diffusingly with hands, once take effect, two days once, and there is obvious therapeutic effect in a week, and is difficult for recurring.Obviously reduce the hair washing number of times and also can keep hair totally salubrious lastingly, be easy to combing.Make hair fluffy, glossy, free from extraneous odour.

For the treatment alopecia, during hair washing, soft hair, wash dry up after, droplet be applied to the alopecia position with the aqueous solution number of hexamethylenamine, smear diffusingly with hands, per two days of the last week was once promptly seen alopecia and obviously reduces after the week, from second all per two to four days once, obviously see the fine hair on birds or animals hair that newly grows at the alopecia position after two weeks, felt to obtain the hair showed increased, and progressively recovered elegance in the past in three months.Especially remarkable to taking off excessive property alopecia effect.

Because of the character of hexamethylenamine is colourless glossiness crystallization or white crystalline powder, so after smearing, may on scalp, stay one deck white crystalline powder, gently rub with have gentle hands and smear promptly and can disappear, do not influence normal live and work, do not affect the appearance yet.

Toxic and side effects: also do not have known toxic and side effects at present.

The patient affected part has the skin damage unsuitable.

Utilize the distinctive pharmacological of hexamethylenamine, hexamethylenamine is added shampoo (shampoo, shampoo, fancy soap etc.), can play cleaning hair, the prevention dandruff equally, reduce the scalp worry of scratching where it itches, play the effect of hair strengthening additional issue, become have multiple efficacies shampoo.

Use it for preparation Hair grooming perfume, promptly become have the prophylactic treatment prevention dandruff, the special perfume of scalp pruritus, anticreep additional issue effect, the easily anti-alopecia of removing scurf and relieving itching.

This product is a colorless and odorless, and skin is not had direct zest, not can to scalp produce overstimulation and the injury human body.Attached: the physicochemical characteristic of hexamethylenamine and pharmacological action (drawing the national drug standards) from National Drug Administration

(chemical name is: hexamethylenetetramine, chemical molecular formula are hexamethylenamine: C6H12N4) be its active ingredient.It is product by formaldehyde and ammonia condensation.

The character of hexamethylenamine is: colourless glossiness crystallization or white crystalline powder, almost odorless, the just sweet back of flavor hardship.Soluble in water, be dissolved in ethanol, be dissolved in ether hardly.

Pharmacological action: this product has sterilization, convergence, anti-hidropoiesis, is Cidex-7.

External can be controlled tinea, hidroschesis, control bromhidrosis.

Back for oral administration is met the aciduria decomposition and is produced formaldehyde and play bactericidal action, is used for slight urinary tract infection; But also intravenous injection.

Claims

1, the application in the medicament of hexamethylenamine, scalp pruritus many, alopecia at preparation treatment prevention dandruff, the medicament of its preparation is the human body head external, it is characterized in that: can prophylactic treatment many, the scalp pruritus of dandruff, alopecia symptom and symptomes complice thereof, can promote hair growth.

2, application according to claim 1 is characterized in that: make medicament, can treat that dandruff is many, scalp pruritus, alopecia symptom and symptomes complice thereof, can promote hair growth.

3, application according to claim 1 is characterized in that: be made into shampoo, can prophylactic treatment many, scalp pruritus of dandruff or alopecia symptom, can promote hair growth.

4, application according to claim 1 is characterized in that: be made into Hair grooming perfume, promptly become have that prophylactic treatment prevention dandruff is many, scalp pruritus, alopecia symptom and trichogenous perfume.