CN100534534C - 用储存的红血球改善氧传送的方法 - Google Patents

用储存的红血球改善氧传送的方法 Download PDF

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Publication number
CN100534534C
CN100534534C CNB028177347A CN02817734A CN100534534C CN 100534534 C CN100534534 C CN 100534534C CN B028177347 A CNB028177347 A CN B028177347A CN 02817734 A CN02817734 A CN 02817734A CN 100534534 C CN100534534 C CN 100534534C
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CN
China
Prior art keywords
red blood
hemoglobin
blood cells
stored
stored red
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB028177347A
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English (en)
Chinese (zh)
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CN1553817A (zh
Inventor
托马斯·C·佩奇
威廉·R·赖特
小爱德华·E·雅各布斯
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Biopure Corp
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Biopure Corp
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Publication date
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNB028177347A 2001-09-10 2002-09-10 用储存的红血球改善氧传送的方法 Expired - Fee Related CN100534534C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/950,270 US6811778B2 (en) 2001-09-10 2001-09-10 Method for improving oxygen transport by stored red blood cells
US09/950,270 2001-09-10

Publications (2)

Publication Number Publication Date
CN1553817A CN1553817A (zh) 2004-12-08
CN100534534C true CN100534534C (zh) 2009-09-02

Family

ID=25490200

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028177347A Expired - Fee Related CN100534534C (zh) 2001-09-10 2002-09-10 用储存的红血球改善氧传送的方法

Country Status (5)

Country Link
US (2) US6811778B2 (https=)
EP (1) EP1425047A4 (https=)
JP (1) JP2005511504A (https=)
CN (1) CN100534534C (https=)
WO (1) WO2003022312A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5328159B2 (ja) 2005-03-01 2013-10-30 セルカコア・ラボラトリーズ・インコーポレーテッド 多波長センサ発光体
US8265723B1 (en) 2006-10-12 2012-09-11 Cercacor Laboratories, Inc. Oximeter probe off indicator defining probe off space
EP2514473A1 (en) * 2006-11-07 2012-10-24 The General Hospital Corporation Nitric oxide delivery device
US8781544B2 (en) 2007-03-27 2014-07-15 Cercacor Laboratories, Inc. Multiple wavelength optical sensor
US8374665B2 (en) 2007-04-21 2013-02-12 Cercacor Laboratories, Inc. Tissue profile wellness monitor
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
US9839381B1 (en) 2009-11-24 2017-12-12 Cercacor Laboratories, Inc. Physiological measurement system with automatic wavelength adjustment
GB2487882B (en) 2009-12-04 2017-03-29 Masimo Corp Calibration for multi-stage physiological monitors
JP6389125B2 (ja) 2011-11-07 2018-09-12 ザ ジェネラル ホスピタル コーポレイション 赤血球の処理法
IN2014MN02089A (https=) 2012-03-20 2015-09-11 Einstein Coll Med
CA3070172A1 (en) 2017-07-18 2019-01-24 VirTech Bio, Inc. Blood substitutes comprising hemoglobin and methods of making
US20210352887A1 (en) * 2018-10-12 2021-11-18 VirTech Bio, Inc. Oxygenation media for ex-vivo preservation of organs and tissues

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1312009C (en) 1986-11-10 1992-12-29 Carl W. Rausch Extra pure semi-synthetic blood substitute
EP0277289B8 (en) * 1986-11-10 2003-05-21 Biopure Corporation Extra pure semi-synthetic blood substitute
US5344393A (en) * 1992-02-28 1994-09-06 Alliance Pharmaceutical Corp. Use of synthetic oxygen carriers to facilitate oxygen delivery
US5865784A (en) 1995-06-07 1999-02-02 Alliance Pharmaceutical Corp. Method of hemodilution facilitated by monitoring oxygenation status

Also Published As

Publication number Publication date
US20050079162A1 (en) 2005-04-14
CN1553817A (zh) 2004-12-08
US6811778B2 (en) 2004-11-02
WO2003022312A1 (en) 2003-03-20
EP1425047A1 (en) 2004-06-09
US7267817B2 (en) 2007-09-11
EP1425047A4 (en) 2009-07-22
US20030049232A1 (en) 2003-03-13
JP2005511504A (ja) 2005-04-28

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