CN100510049C - Multi-channel assembled automatic fluid distributor - Google Patents
Multi-channel assembled automatic fluid distributor Download PDFInfo
- Publication number
- CN100510049C CN100510049C CNB2006100080891A CN200610008089A CN100510049C CN 100510049 C CN100510049 C CN 100510049C CN B2006100080891 A CNB2006100080891 A CN B2006100080891A CN 200610008089 A CN200610008089 A CN 200610008089A CN 100510049 C CN100510049 C CN 100510049C
- Authority
- CN
- China
- Prior art keywords
- cam
- squeegee roller
- roller assembly
- connecting rod
- pen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
An automatic multi-channel assembled fluid distributor consists of cam assembly installed in framed stand horizontally, upper and lower extruding wheel assemblies fixed installed on top and bottom of cam assemblies separately, and upper and lower catch-pipe assemblies fixed installed on top and bottom of upper and lower extruding wheel assemblies; elastic of catch-pipe assembly pipe is connected with fluid joint, whose external end is connected with outputting end of multiple manifold with one inputting end and multiple outputting ends; step-by-step motor installed on framed stand drives cam assembly rotate by transmission mechanism. It has different positioning and connecting styles, multiple inputting-outputting styles; it realizes automatic switch by driver and can be used to separation automatic samples, multiple samples and multi-channel nutrients supply in biological and medicinal engineering.
Description
Technical field
The present invention relates to biology, space biology and biotechnology, engineering in medicine.
Background technology
Fluid distributor is a kind of equipment of controlling flow direction of flow, is mainly used in fields such as engineering in medicine and biotechnology.Fluid distributor in the past generally has input, output block and hybrid chamber parts, concrete using method---input block imports hybrid chamber with different liquid or gas, in hybrid chamber (reaction bed), produce the mix products that chemical reaction or physical reaction obtain needs, export by output block then.The difference of general fluid divider is the different of input block, output block and mixing chamber, and purpose all is to obtain mix products.This patent is mainly used in that the fluidic self-orientation distributes and directional collecting, solves cell cultures in the Bioexperiment of present space, the automatic multiple class of tissue culture is repeatedly taken a sample with fixing.When various product sampling and hyperchannel are carried, easily mixing, easy pollution effect experimental result.Repeatedly take a sample and fix and the hyperchannel nutritive medium is supplied with automatically in order to reach automatic multiple class, satisfy high-quality, the efficient and controlled purpose of scientific research and production, we have proposed " a kind of multi-channel assembled fluid distributor " this invention.Multi-channel assembled fluid distributor is by the various combination mode of cam and the method for attachment of many menifolds, can make device have the function combinations of multiple input and output, by cam extruding elasticity transport pipe, the control fluidic flows, avoided contacting of fluid and distributor body, can realize mutually isolating not have in the multiple fluid course of conveying mixing, reduce pollution channel, the present invention has the little advantage such as in light weight of volume in addition.
Summary of the invention
The objective of the invention is to solve cell cultures in the Bioexperiment of present space, the automatic multiple class of tissue culture is repeatedly taken a sample and the fixed problem.
Technical scheme of the present invention is as follows:
Multi-channel assembled automatic fluid distributor (see figure 1) provided by the invention comprises:
One frame support 3;
One left and right sides framework level by described frame support 3 is installed on the cam pack 5 within the frame support 3; Described cam pack 5 comprises:
One horizontal cam axle 51;
Be symmetrical arranged the cam 54 of trench and N+1 diameter catch 53 on N wheel hub greater than described cam 54 diameters; Described cam 54 radial direction evenly are provided with even number pilot hole 541;
Described cam 54 is fixedly mounted on the described horizontal cam axle 51 by even compartment of terrain, different pilot holes 541 location;
Described catch 53 by bolt 52 polyphone of described horizontal cam axle 51 upper and lowers be fixed in the interval between the described cam 54; Described catch 53 and cam 54 are placed at interval, and outermost is catch;
One left and right sides framework horizontal symmetrical by described frame support 3 is installed on the top end rail 100 and the bottom end rail 200 of cam pack 5 above and belows; And
Be fixedly mounted on the last squeegee roller assembly 60 on the top end rail 100; With the following squeegee roller assembly 6 that is fixedly mounted on the bottom end rail 200; The described squeegee roller assembly 60 of going up is made up of N squeegee roller assembly unit respectively with following squeegee roller assembly 6; Each squeegee roller assembly unit comprises: a squeegee roller 62, a wheel carrier 63, a crossbeam 64, a connecting rod 65, a spring 66, a upper cover plate 67 and a crushing block 68; Described squeegee roller 62 is fixed on the wheel carrier 63, wheel carrier 63 is connected with connecting rod 65 by screw, connecting rod 65 usefulness axle head circlips and flat gasket are positioned in the center positioning hole in the crossbeam 64, spring 66 is enclosed within on the connecting rod 65, upper cover plate 67 is limited in spring 66 in the center positioning hole of crossbeam 64, and connecting rod 65 lower ends are connected with crushing block 68; Cam (54) wheel hub in described squeegee roller 62 and the cam pack 5 contacts wheel hub and links to each other; Two groups that described squeegee roller assembly unit dosis refracta is identical are fixed on described top end rail 100 and the bottom end rail 200 symmetrically and side by side;
A pair of be fixedly mounted on respectively described go up squeegee roller assembly 60 tops and following squeegee roller assembly 6 belows on hold a writing brush or pen-write assembly with under the assembly 7 that holds a writing brush or pen-write; Hold a writing brush or pen-write on the described assembly and the assembly 7 that holds a writing brush or pen-write down is made up of the individual assembly unit that holds a writing brush or pen-write of N respectively; Each assembly unit that holds a writing brush or pen-write comprises: a pair of side shield 12, a flexible pipe 11, a fluid joint 10 and a lower cover 9; Described N is 4-12;
Described a pair of side shield 12 is fixedly mounted on the both sides of crossbeam 64 lower surfaces of described squeegee roller assembly unit by the screw symmetry, forms an open slot therebetween; The crushing block 68 that links to each other with connecting rod 65 lower ends in the described squeegee roller assembly unit is positioned at described open slot; Described a pair of side shield 12 medial surfaces are provided with consistent with the described open slot opening direction groove of laterally holding; Laterally hold flexible pipe 11 is housed in the groove; The two ends of described flexible pipe 11 are enclosed within the inner of fluid coupling 10; One step lower cover 9 is fixed on the lower surface of this a pair of side shield 12, and its step less than described open slot width is positioned at described open slot and contacts with described flexible pipe 11; Fluid coupling 10 outer ends are connected with the output terminal of the many menifolds 14 with an input terminus and many output terminals respectively, and the input terminus of described many menifolds 14 is connected with transferpump; Also comprise:
Be contained in the stepper-motor 1 on the frame support 3; Described stepper-motor 1 drives cam pack 5 by transmission rig 2 and rotates.
Described stepper-motor 1 has the controller 8 of controlling its rotating speed.Described flexible pipe 11 is a silicone rubber tube.
In use, jack-up squeegee roller assembly when the cam in the cam pack 5 54 forwards a high position to, cam 54 unclamps the squeegee roller assembly when forwarding low level to; Squeegee roller assembly (see figure 3) is made up of major partss such as squeegee roller 62, wheel carrier 63, crossbeam 64, connecting rod 65, spring 66, upper cover plate 67 and crushing blocks 68; When squeegee roller 62 during by jack-up drivening rod 65 move downward, connecting rod 65 is compression spring 66 simultaneously, drives crushing block 68 and compresses silicone rubber tube 11, closes the fluidic transfer passage; When squeegee roller 62 unclamped, the elastic force of dependence spring 66 drove on the squeegee roller 62 and moves, and connecting rod 65 and crushing block 68 move upward simultaneously, unclamp the flexible pipe 11 in the assembly that holds a writing brush or pen-write, and flexible pipe 11 relies on the elastic recovery original state of self, and transport pipe is opened automatically;
The cam pack (see figure 4) is made up of N identical cam 64, each cam 64 (see figure 2) radial direction uniform distribution even number pilot hole 641 (central angle among Fig. 2 between two pilot holes 641 is 45 °), cam 64 is by different pilot hole location, can obtain different array modes, obtain different circulation styles simultaneously; Transport pipe one end by crushing block 68 controls connects many menifolds in addition, and an end is connected with incubator, and many menifolds have a plurality of interfaces, can be as input/output port; When cam pack 5 is in a kind of locator means and many menifolds mode of connection when constant, stepper-motor 1 drives moving 45 degree of cam pack 5 revolutions, just can obtain a kind of I/O mode, change the locator means of cam set 5 or the mode of connection of many menifolds and can obtain new I/O mode, we just can obtain a kind of I/O mode of permutation and combination type like this.Thereby solved cell cultures in the Bioexperiment of space, the automatic multiple class of tissue culture is repeatedly taken a sample and the fixed problem.
Advantage of the present invention is, can be by the different locator means of the cam in the cam pack 5 and the mode of connection of many menifolds, obtain multiple input, the way of output, and can automatically switch by driving mechanism, the isolation fully that helps in biotechnology and the medical engineering is taken a sample automatically, is repeatedly taken a sample and the sampling of various product, and the hyperchannel nutritive medium is supplied with.
Description of drawings
Fig. 1 is the structural representation of multi-channel assembled automatic fluid distributor of the present invention;
Fig. 2 is the structural representation of cam;
Fig. 3 is the structural representation of squeegee roller assembly;
Fig. 4 is the structural representation of cam set etc.
Embodiment
The structure of multi-channel assembled fluid distributor of the present invention as shown in Figure 1; The cam pack 5 that present embodiment contains 6 cams 54 (quantity of cam can be 4 to 12) is installed within the frame support 3 by the left and right sides framework level of frame support 3; The mechanism that holds a writing brush or pen-write comprises 62 fens two groups of upper and lowers that are installed in cam pack 5 of 12 squeegee rollers; The squeegee roller 62 of squeegee roller assembly 6 rolls with cam 54 and contacts, stepper-motor 1 and transmission rig 2 are installed in the lower left corner, stepper-motor 1 drives cam pack 5 by transmission rig 2 and rotates, the corresponding squeegee roller assembly of jack-up when cam 54 forwards a high position to, cam 54 unclamps corresponding squeegee roller assembly when forwarding low level to; When squeegee roller 62 during by jack-up drivening rod 65 move downward, connecting rod 65 is compression spring 66 simultaneously, drives crushing block 68 and compresses silicone rubber tube 11, closes the fluidic transfer passage; When squeegee roller 62 unclamped, the elastic force of dependence spring 66 drove on the squeegee roller 62 and moves, and connecting rod 65 and crushing block 68 move upward simultaneously, unclamp the silicone rubber tube 11 in the assembly that holds a writing brush or pen-write, and silicone rubber tube 11 relies on the elastic recovery original state of self, and transport pipe is opened automatically.
Cam pack 5 (see figure 4)s are made up of 6 identical cams 54,54 on 6 cams are separated by catch 53 (the catch diameter is greater than the cam diameter), article two, standing bolt is connected into the groove that forms between cam pack 5, two cams with cam 54 and catch 53 and guarantees that squeegee roller 62 rolls in groove; 8 pilot holes 541 of each cam 54 (see figure 2) radial direction uniform distribution, the trench opening on cam 54 wheel hubs is symmetrically distributed, and the cam 54 of different trench opening directions (angle) is cascaded, and can obtain different array modes;
Squeegee roller assembly (see figure 3) is made up of major partss such as squeegee roller 62, wheel carrier 63, crossbeam 64, connecting rod 65, spring 66, upper cover plate 67 and crushing blocks 68, squeegee roller 62 is fixed on the wheel carrier 63, wheel carrier is connected with connecting rod 65 by screw, connecting rod 65 usefulness axle head circlips and flat gasket are positioned in the pilot hole of crossbeam 64, spring 66 is enclosed within on the connecting rod 65, upper cover plate 67 is limited in spring 66 in the slotted eye of crossbeam 64, and connecting rod 65 lower ends are connected with crushing block 68;
The assembly (see figure 3) that holds a writing brush or pen-write comprises side shield 12, silicone rubber tube 11, fluid coupling 10 and lower cover 9, left and right sides baffle plate 12 by screw retention on crossbeam 64, silicone rubber tube 11 two ends are enclosed within on fluid coupling 10 the inners, and be installed in the holding in the hole of left and right sides baffle plate 12, lower cover 9 is fixed on the centre of left and right sides baffle plate 12, and silicone rubber tube is held.Fluid coupling 10 outer ends can be connected with the output terminal of polytype many menifolds 14 respectively as required, and many menifold 14 input terminuss are connected with transferpump, and many menifolds 14 can be fixed on the appropriate location.
Whole device amounts to 12 passages, can be divided into 4 groups, easy to assemble, easy combination, is convenient to automatic control, and multiple I/O mode is arranged, and overall dimensions is 150 * 130 * 50mm, and weight is less than 2kg.
Claims (3)
1, a kind of multi-channel assembled automatic fluid distributor is characterized in that, comprising:
One frame support (3);
One left and right sides framework level by described frame support (3) is installed on the cam pack (5) within the frame support (3); Described cam pack (5) comprising:
One horizontal cam axle (51);
Be symmetrical arranged the cam (54) of trench and N+1 diameter catch (53) on N wheel hub greater than described cam (54) diameter; Described cam (54) radial direction evenly is provided with even number pilot hole (541);
Described cam (54) is fixedly mounted on the described horizontal cam axle (51) by even compartment of terrain, different pilot hole (541) location;
Be fixed on to bolt (52) polyphone of described catch (53) by being positioned at described horizontal cam axle (51) upper and lower the interval between the described cam (54); Described catch (53) and cam (54) are placed at interval, and outermost is catch;
One left and right sides framework horizontal symmetrical by described frame support (3) is installed on the top end rail (100) and the bottom end rail (200) of cam pack (5) above and below; And
Be fixedly mounted on the last squeegee roller assembly (60) on the top end rail (100); With the following squeegee roller assembly (6) that is fixedly mounted on the bottom end rail (200); Described upward squeegee roller assembly (60) and following squeegee roller assembly (6) are made up of N squeegee roller assembly unit respectively; Each squeegee roller assembly unit comprises: a squeegee roller (62), a wheel carrier (63), a crossbeam (64), a connecting rod (65), a spring (66), a upper cover plate (67) and a crushing block (68); Described squeegee roller (62) is fixed on the wheel carrier (63), wheel carrier (63) is connected with connecting rod (65) by screw, connecting rod (65) is positioned in the center positioning hole in the crossbeam (64) with axle head circlip and flat gasket, spring (66) is enclosed within on the connecting rod (65), upper cover plate (67) is limited in spring (66) in the center positioning hole of crossbeam (64), and connecting rod (65) lower end is connected with crushing block (68); Cam (54) wheel hub in described squeegee roller (62) and the cam pack (5) contacts wheel hub and links to each other; Two groups that described squeegee roller assembly unit dosis refracta is identical are fixed on described top end rail (100) and the bottom end rail (200) symmetrically and side by side;
A pair of be fixedly mounted on respectively described go up squeegee roller assembly (60) top and following squeegee roller assembly (6) below on hold a writing brush or pen-write assembly with under the assembly (7) that holds a writing brush or pen-write; Hold a writing brush or pen-write on the described assembly and the assembly (7) that holds a writing brush or pen-write down is made up of the individual assembly unit that holds a writing brush or pen-write of N respectively; Each assembly unit that holds a writing brush or pen-write comprises: a pair of side shield (12), a flexible pipe (11), a fluid joint (10) and a lower cover (9); Described N is 4-12;
Described a pair of side shield (12) is fixedly mounted on the both sides of crossbeam (64) lower surface of described squeegee roller assembly unit by the screw symmetry, forms an open slot therebetween; The crushing block (68) that links to each other with connecting rod (65) lower end in the described squeegee roller assembly unit is positioned at described open slot; Described a pair of side shield (12) medial surface is provided with consistent with the described open slot opening direction groove of laterally holding; Laterally hold flexible pipe (11) is housed in the groove; The two ends of described flexible pipe (11) are enclosed within the inner of fluid coupling (10); One step lower cover (9) is fixed on the lower surface of this a pair of side shield (12), and its step less than described open slot width is positioned at described open slot and contacts with described flexible pipe (11); Fluid coupling (10) outer end is connected with the output terminal of the many menifolds (14) with an input terminus and many output terminals respectively, and the input terminus of described many menifolds (14) is connected with transferpump; Also comprise:
Be contained in the stepper-motor (1) on the frame support (3); Described stepper-motor (1) drives cam pack (5) by transmission rig (2) and rotates.
2, by the described multi-channel assembled automatic fluid distributor of claim 1, it is characterized in that described stepper-motor (1) has the controller (8) of controlling its rotating speed.
3, by the described multi-channel assembled automatic fluid distributor of claim 1, it is characterized in that described flexible pipe (11) is a silicone rubber tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100080891A CN100510049C (en) | 2006-02-28 | 2006-02-28 | Multi-channel assembled automatic fluid distributor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100080891A CN100510049C (en) | 2006-02-28 | 2006-02-28 | Multi-channel assembled automatic fluid distributor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101029297A CN101029297A (en) | 2007-09-05 |
| CN100510049C true CN100510049C (en) | 2009-07-08 |
Family
ID=38714851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100080891A Expired - Fee Related CN100510049C (en) | 2006-02-28 | 2006-02-28 | Multi-channel assembled automatic fluid distributor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100510049C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102418799B (en) * | 2011-06-28 | 2013-08-07 | 李飞宇 | Push-rod type water-fluid reversing valve |
| CN103272658B (en) * | 2013-06-25 | 2015-04-22 | 南京理工大学 | Double-channel automatic distribution device for micro reagents |
| US9222935B1 (en) * | 2015-05-28 | 2015-12-29 | Pixcell Medical Technologies Ltd | Fluid sample analysis system |
| CN106641336B (en) * | 2017-02-21 | 2023-06-16 | 北京康洁之晨水处理技术有限公司 | Rotary cam disc type pressure distributor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2646503Y (en) * | 2003-09-29 | 2004-10-06 | 金洪水 | Multi-fluid distributor |
-
2006
- 2006-02-28 CN CNB2006100080891A patent/CN100510049C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2646503Y (en) * | 2003-09-29 | 2004-10-06 | 金洪水 | Multi-fluid distributor |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101029297A (en) | 2007-09-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69628291T2 (en) | FERMENTATION PROCESS BY MEANS OF CENTRIFUGATION | |
| TWI438273B (en) | High-throughput perfusative microfluidic cell culture wafers for miniaturized three-dimensional cell culture | |
| CN100510049C (en) | Multi-channel assembled automatic fluid distributor | |
| US20230279323A1 (en) | Fluidic devices including microplates with interconnected wells | |
| US3827943A (en) | Culture apparatus | |
| EP2831221A1 (en) | Cell culture apparatus and culture methods using same | |
| CN102234614B (en) | Micro-fluidic cell suspension culture chip and application thereof | |
| WO2011130617A2 (en) | An integrated bioreactor and separation system and methods of use thereof | |
| JPS62502376A (en) | Reactor for culturing biological materials such as fixed cells | |
| EP2151491A2 (en) | Multichamber bioreactor with bidirectional perfusion integrated in a culture system for tissue engineering strategies | |
| CN208055362U (en) | A kind of cell culture apparatus convenient for adjusting culture solution concentration | |
| Bramble et al. | Plant cell culture using a novel bioreactor: the magnetically stabilized fluidized bed | |
| CN109569755B (en) | Liquid drop mass production device | |
| US20030054546A1 (en) | Biocatalyst chamber encapsulation system for bioremediation and fermentation | |
| CN109929762A (en) | A kind of cell culture apparatus | |
| CA2568646A1 (en) | Liquid/gas phase exposure reactor for cell cultivation | |
| WO2007008688A2 (en) | Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor | |
| CN202116557U (en) | Small-sized fermentation equipment | |
| CN202124632U (en) | Stem cell culture perfusing device | |
| CN209098693U (en) | A kind of intermittent streaming electrotransfection device | |
| CN114736787A (en) | Nucleic acid elution and detection device | |
| WO2017101096A1 (en) | Combined bioreactor bin applicable to perfusion culture | |
| CN106635796B (en) | Device and fixed cultural method for cell fixation culture | |
| CN111996112B (en) | Microfluidic chip device, preparation method thereof and method for producing biomass by microalgae | |
| CN114107057A (en) | Reactor for separating extracellular vesicles |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090708 Termination date: 20160228 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |