CN100509013C - Conditioning qi-invigorating weight-reducing extract - Google Patents

Abstract

The invention discloses a conditioning qi-invigorating weight-reducing extract which is prepared from the following constituents (by weight percent) through conventional process: rhubarb horsetails 5-10, peppermint 1-5, licorice root 1-5, Equisetum hiemale L. 1-5, ginseng 3-8, borneol 1-5, fine Chinese caterpillar fungus 1-5, American ginseng 1-5, and Cinnamomum cassia 1-5.

Description

A kind of conditioning qi-invigorating weight-reducing extract

(1) technical field: the present invention relates to a kind of conditioning qi-invigorating weight-reducing extract, belong to Chinese medicine conditioning fat-reducing technical field.

(2) background technology: at present ways of preventing obesity have multiple, as: go on a diet, jejunitas, this method can be given people healthyly brings very big threat, can cause symptoms such as heart failure, hypotension, anemia when serious; And Instrument defatting, not only the course of treatment long, produce little effect, and very painful when using; A lot of weight reduction with drugs are also arranged now, its major function is to control appetite of people by force, cause malaise symptoms such as hunger sensation, nervous, diarrhoea, health perspire abnormal sweat, the whole body is unable, dizzy, blood pressure is low easily like this, side effect is very big, give that people are healthy to bring very big threat, and curative effect is very not remarkable, easily recurrence.

(3) summary of the invention: the objective of the invention is to overcome the deficiency of above-mentioned prior art and a kind of evident in efficacy, short treating period is provided, is difficult for recurrence, without any side effects, body health benefits, conditioning qi-invigorating weight-reducing extract easy to use.

Purpose of the present invention can realize by following measure: a kind of conditioning qi-invigorating weight-reducing extract, it is characterized in that it by following parts by weight of Chinese traditional medicine, makes by the unguentum conventional method: Radix Et Rhizoma Rhei 5～10 Herba Menthaes 1～5 Radix Glycyrrhizae 1～5 Herba Equiseti Hiemalis 1～5 Radix Ginseng 3～8 Borneolum Syntheticums 1～5 Cordyceps 1～5 Radix Panacis Quinquefolii 1～5 Cortex Cinnamomi 1～5

Implementing a kind of preferred embodiment of the object of the invention is: it is made by the unguentum conventional method by following parts by weight of Chinese traditional medicine:

Radix Et Rhizoma Rhei 8 Herba Menthaes 3 Radix Glycyrrhizaes 3 Herba Equiseties Hiemalis 3 Radix Ginsengs 5

Borneolum Syntheticum 3 Cordyceps 3 Radix Panacis Quinquefoliis 3 Cortex Cinnamomis 3

The effect of composition of the present invention is:

Radix Et Rhizoma Rhei: have purging heat to relax the bowels, removing pathogenic heat from blood and toxic substance from the body by the effect of becoming silted up and stimulating the menstrual flow, is mainly used in and treats damp and hot stagnating, constipation, conjunctival congestion and swelling pain, the swollen furuncle of pain, congestion amenorrhea, damp-heat dysentery, diseases such as jaundice edema.

Herba Menthae: have dispelling wind and heat pathogens, the clear sharp head, the sensible effect of inducing sweat is mainly used in the treatment anemopyretic cold, headache conjunctival congestion, laryngopharynx swelling and pain, stagnation of QI due to depression of the liver, elbow pain uncomfortable in chest, diseases such as trusted subordinate's overflow.

Radix Glycyrrhizae: have heat-clearing and toxic substances removing, lung moistening detoxifcation, the effect of coordinating the actions of various ingredients in a prescription is mainly used in the insufficiency of the spleen asthenia of treatment, and the cough stagnation of QI will be eaten poisoning, gastral cavity abdomen or extremity contraction be anxious disease such as have a pain.

The Herba Equiseti Hiemalis: the wind nebula removing that looses, hemostasia and detumescence cures mainly corneal nebula, epiphora induced by wind, small piece of land surrounded by water skin ulcer is not held back.

Radix Ginseng: quench the thirst and controlling collapse and body void after being ill in invigorating QI to relieve exhaustion the Tianjin of calming the nerves.

Borneolum Syntheticum: have the refreshment of having one's ideas straightened out, the antidotal effect is mainly used in the treatment coma, diseases such as conjunctival congestion aphtha sore throat skin infection.

Cordyceps: have nourishing the lung and kidney, the effect of hemostasis and phlegm is mainly used in treatment and just coughs dyspnea due to deficiency, and soreness of waist and knee joint, body void are not multiple, diseases such as spontaneous perspiration cold syndrome of the stomach.

Radix Panacis Quinquefolii: have boosting qi and nourishing yin, the effect of relieving inflammation or internal heat and promoting the production of body fluid.Be mainly used in the treatment chronic cough of deficiency lung, heat impairing vital QI the moon, the tired tired thirsty disease of waiting.

Cortex Cinnamomi: have invigorate vital energy and yang, the smart effect that goes up pain of temperature is mainly used in the treatment insufficiency of kidney-YANG, and conjunctival congestion is dizzy, trusted subordinate's cold type of pain, the cold and deficiency of CHONG and REN meridians, diseases such as amenorrhea stomachache.

The test example:

1, the acute toxicity test of external Chinese patent medicine of the present invention

(1) test objective: observe the toxicity reflection that animal subject produces because of Absorption skin.

(2) animal is selected: 4 of the white rabbit of selection 1.5-2kg, male and female half and half.

(3) test is prepared: white rabbit is exposed the exocuticle of white rabbit being tried preceding 24 hours with its both sides, back shearing machine unhairing, and the unhairing scope is each 8cm * 10cm of both sides, adds up to 160cm2.

(3) test method: with 4 of the rabbit after the unhairing, carried out disinfection to trying skin respectively, smear the exocuticle of rabbit with Chinese medicinal ointment of the present invention.

(4) observe and the result: give to be subjected to behind the reagent thing 24 hours, find no and be poisoned to death.Continue to observe 7 days, tried outward appearance, the mental status, appetite, stool, the colour of skin, the breathing of rabbit and do not have any unusual.

Above-mentioned evidence, nontoxic, the safety of external Chinese patent medicine of the present invention.

2, the skin anaphylactic test of external Chinese patent medicine of the present invention

(1) test objective: the purpose of this test is to observe animal skin, and after repeating contact and being subjected to the reagent thing, medicine is in the intravital sensitization reflection of flesh.

(2) animal is selected: the white mice (respectively 15 of male and female) that to select 30 body weight be 100-150g.

(3) test is prepared: tried preceding 24 hours, the hair of 2 * 2cm2 is respectively removed in both sides, white mice back, exposing the exocuticle of white, the skin at unhairing position must not be injured because of unhairing, otherwise be not useable for test.

(4) test method

1. test grouping, by body weight, sex is divided into three groups at random with Cavia porcellus, and 10 every group, male and female half and half.First group is tried medicine of the present invention; Second group of negative control gives excipient (lanoline); The 3rd group of positive control gives 2,4-dinitro-chloro-benzene (DNCB) of 1%.

2. sensitization contact: get and be subjected to reagent thing 0.5g, be mixed with an amount of lanoline excipient, be coated in and tried depilation district, back, Cavia porcellus left side, fix with gauze and adhesive plaster, every animal sub-cage rearing continues 10 hours, the 7th day and the 14th day, in kind repeat once, the negative control group Cavia porcellus is coated with lanoline; Positive thing matched group is coated with 1%DNCB, and method is with being subjected to reagent thing group.

3. excite contact: in last give be subjected to reagent thing sensitization after 14 days, to be subjected to reagent thing 0.5g to be applied to depilation district, guinea pig back right side, remove after 10 hours and be subjected to the reagent thing, at once observe the skin allergy situation, then in 24,48, observed once more in 72 hours, negative and positive controls operation and observational technique is same is subjected to reagent thing group is the lanoline excipient but negative control group is coated with, and positive controls is coated with is 1% DNCB.

(5) observed result: through to 10 hours the observation of sensitization that is subjected to reagent thing group Cavia porcellus and the 7th day, repeated sensitization test (STT) on the 14th day to observe, sensitization contact negative and positive controls is observed and is all found no the erythema generation; After this to exciting the observation of contact test, also find no the generation of erythema phenomenon, by above evidence, external used medicine of the present invention is more normal to the skin reflection, no sensitization reaction.

Clinical data: the present invention is formulated by Chinese crude drug, be various diseases medicine for external use such as treatment obesity and the hypertension that causes by obesity, hyperlipidemia, fatty liver, the applicant added up to treat total case 158 examples from 2002 to 2005 first half of the year, wherein effective 58 examples, produce effects 99 examples, total effective rate 99.4% now is reported as follows:

Processing: with above-mentioned Chinese medicine routinely unguentum preparation technology make conditioning qi-invigorating weight-reducing extract.

Usage: this ointment is spread upon on the acupuncture point of abdominal part, by smearing, rub the reinforcement infiltration that reaches medicine by, hot compress, replenish vigour, 3 times on the one, each 15-20 minute, 30 days was a course of treatment.

Taboo: the spleen deficiency of the lung, kidney qi weak person should not or follow the doctor's advice.

Physical data: 25 examples of sampling, male's 10 examples wherein, women's 15 examples, 43 years old mean age, patient is very fat, and some also suffers from the various diseases that is caused by obesity: as hypertension, hyperlipidemia, fatty liver etc., patient is extremely painful, and weight person seriously influences normal work and life;

Parameters for observation on effect: observe the variation of conditions of patients, the elimination of disease and administration time;

Therapeutic evaluation:

Medication 30 days, symptom obviously alleviate to effectively, and the symptom complete obiteration is a produce effects;

Model case:

38 years old height of the Wang Qing tinkling of pieces of jade woman Mouping District Wuning Nan Guanzhuancun of 1.58 meters Yantai City, obesity for many years, repeatedly therapeutic effect is not good, 184 jin of waistlines of body weight, 3.10 chi hip circumferences, 4.00 chi thigh circumferences 2 before the fat-reducing, 05 chi is through using conditioning qi-invigorating weight-reducing extract after three courses of treatment, 124 jin of waistlines of body weight, 2.40 chi hip circumferences, 2.95 chi thigh circumferences, 1.70 chis.

1.80 meters Yantai City public security sections of Mouping District public security bureau of Sun Jia will 49 years old height of man, all ineffective through multiple method of weight-reducing, preceding 206 jin of waistlines, 3.27 chi hip circumferences, 3.40 chi thigh circumferences, 2.10 chis of fat-reducing are through using conditioning qi-invigorating weight-reducing extract after two courses of treatment before going to a doctor, 178 jin of waistlines of body weight, 2.80 chi hip circumferences, 3.10 chi thigh circumferences, 1.90 chis.

The Mouping District soil pipe chief of office of 1.78 meters Yantai City of Zhou Ruguang 51 years old height of man, obesity for many years, and suffer from diseases such as hypertension, hyperlipidemia, repeatedly therapeutic effect is not good, 204 jin of waistlines of body weight, 3.70 chi hip circumferences, 3.70 chi thigh circumferences, 1.85 chis are through using conditioning qi-invigorating weight-reducing extract after three courses of treatment before the fat-reducing, 169 jin of waistlines of body weight, 2.90 chi hip circumferences, 3.20 chi thigh circumferences, 1.70 chis, the disease that hypertension, hyperlipidemia etc. is caused by obesity obviously alleviates.

The present invention can produce following good effect compared with the prior art: 1, easy to use, and instant effect, no pain, not weak; 2, fat-reducing process is steady, and is lasting, is difficult for bounce-back, has no side effect; 3, the skin that compacts, the toxin expelling relieving constipation; 4, smear by external, the rapid osmotic fat deposit, blood circulation promoting decomposes subcutaneous fat.

During losing weight, full of vitality not weak, the effect with conditioning QI invigorating, is difficult for recurrence, without any side effects, body health benefits, very easy to use at evident in efficacy, short treating period.

(4) specific embodiment: following the specific embodiment of the present invention is elaborated:

Embodiment 1: get Radix Et Rhizoma Rhei 5 gram, Herba Menthae 1 gram, Radix Glycyrrhizae 1 gram, Herba Equiseti Hiemalis's 1 gram, Radix Ginseng 3 grams, Borneolum Syntheticum 1 gram, Cordyceps 1 gram, Radix Panacis Quinquefolii 1 gram, Cortex Cinnamomi 1 and restrain routinely that unguentum preparation technology makes conditioning qi-invigorating weight-reducing extract.

Embodiment 2: get Radix Et Rhizoma Rhei 8 gram, Herba Menthae 3 grams, Radix Glycyrrhizae 3 grams, Herba Equiseti Hiemalis's 3 grams, Radix Ginseng 5 grams, Borneolum Syntheticum 3 grams, Cordyceps 3 grams, Radix Panacis Quinquefolii 3 grams, Cortex Cinnamomi 3 and restrain routinely that unguentum preparation technology makes conditioning qi-invigorating weight-reducing extract.

Embodiment 3: get Radix Et Rhizoma Rhei 10 gram, Herba Menthae 5 grams, Radix Glycyrrhizae 5 grams, Herba Equiseti Hiemalis's 5 grams, Radix Ginseng 8 grams, Borneolum Syntheticum 5 grams, Cordyceps 5 grams, Radix Panacis Quinquefolii 5 grams, Cortex Cinnamomi 5 and restrain routinely that unguentum preparation technology makes conditioning qi-invigorating weight-reducing extract.

Claims (2)

1, a kind of conditioning qi-invigorating weight-reducing extract is characterized in that it by following parts by weight of Chinese traditional medicine, makes by the unguentum conventional method:

Radix Et Rhizoma Rhei 5～10 Herba Menthaes 1～5 Radix Glycyrrhizae 1～5 Herba Equiseti Hiemalis 1～5 Radix Ginseng 3～8

Borneolum Syntheticum 1～5 Cordyceps 1～5 Radix Panacis Quinquefolii 1～5 Cortex Cinnamomi 1～5.

2, a kind of conditioning qi-invigorating weight-reducing extract according to claim 1 is characterized in that it by following parts by weight of Chinese traditional medicine, makes by the unguentum conventional method:

Radix Et Rhizoma Rhei 8 Herba Menthaes 3 Radix Glycyrrhizaes 3 Herba Equiseties Hiemalis 3 Radix Ginsengs 5

Borneolum Syntheticum 3 Cordyceps 3 Radix Panacis Quinquefoliis 3 Cortex Cinnamomis 3.