CN100502655C - Selective insecticides and/or acaricides based on substituted cyclic dicarbonyl compounds and safeners - Google Patents

Abstract

The invention relates to the use of selective insecticidal and/or acaricidal agents for controlling insects and/or arachnids. Said insecticidal and/or acaricidal agents are characterized by an active moiety of an active substance combination comprising (a) at least one substituted, cyclic dicarbonyl compound of formula (I), wherein W, X, Y, and Z have the meaning indicated in the description while CDC represents one of the dicarbonyl radicals mentioned in the description, and (b) at least one compound that improves crop plant tolerance and is part of the group of compounds indicated in the description. Also disclosed is a method for controlling insects and/or arachnids using the inventive agents.

Description

Based on the cyclic dicarbonyl compounds that replaces and the selective insecticide and/or the miticide of safener

The present invention relates to the purposes of selectivity desinsection and/or acaricidal activity combinations of compounds (combination), described bond contains, first, the cyclic dicarbonyl compounds and second that replaces, at least a compound that improves the crop compatibility, this bond are used in selectivity control insect and/or tetranychid in the various crop of useful plants.

Known 4-chlorine and 4-nitro-4-phenyl-pyrazole base-3,5-diketone (WO 99/20610) has herbicide effect, and the pyrrolidines-2 that 3-halogen and 3-nitro-3-phenyl replaces, 4-diketone and 4-oxo furans-2-ketone (JP-A 12 086 628) have and kill mite and insecticidal action, also from WO03/029 213, DE-A 103 01805, WO 03/,045 957 and WO 20,04/,069 841 known they weeding, kill mite and insecticidal action.

Also from WO 20,04/,037 749, know 2-chloro-2-benzyl ring pentane-1,3-diketone and 2-chloro-2-cyclohexylbenzene-1,3-diketone.

From WO 2005/016933, know the 4-chloro-4-Phenylpyrazole alkane-3 with weeding and desinsection/acaricidal action, 5-diketone equally.

And, to also existing description (WO 2004/064520) of selective herbicide based on cyclic dicarbonyl compounds that replaces and safener.

Yet, the compatibility of these compounds, particularly the compatibility with monocot crops is not entirely satisfactory under all situations.

Beat allly be, the cyclic dicarbonyl compounds that has now found that some replacement is with the following compound (safener/antipoison) of crop compatibility that improves when using, prevent infringement admirably to crop, and can be particularly advantageously as having the conjugate preparations of wide spectrum effect, be used for selectivity control insect, or even in the useful monocotyledonous crop---in the such as grain---insect.

The invention provides the selectivity desinsection of the active agent combinations that contains effective dose and/or the purposes that miticide composition is used to prevent and treat insect and/or arachnid, described active agent combinations contains following component:

(a) cyclic dicarbonyl compounds of the replacement of at least a formula (I) that comprises whole isomeric forms

Wherein,

W and Z represent hydrogen, halogen, alkyl, thiazolinyl, alkynyl, alkoxyl, alkene oxygen base, haloalkyl, halogenated alkoxy, haloalkene oxygen base, nitro or cyano group independently of one another,

X represents halogen, alkyl, thiazolinyl, alkynyl, alkoxyl, alkene oxygen base, alkylthio group, alkyl sulphinyl, alkyl sulphonyl, haloalkyl, halogenated alkoxy, haloalkene oxygen base, nitro or cyano group,

Y represents optional phenyl or the heteroaryl that replaces of hydrogen, halogen, alkyl, haloalkyl, halogenated alkoxy, nitro, cyano group or representative,

CDC represents one of following group

Perhaps

Wherein,

A represents hydrogen, the alkyl of optional separately halo, thiazolinyl, alkoxyalkyl, alkylthio alkyl, the cycloalkyl of the saturated or undersaturated optional replacement that replaced by hetero atom of optional at least one annular atoms wherein, perhaps choose aryl, aralkyl or heteroaryl separately wantonly by halogen, alkyl, haloalkyl, alkoxyl, halogenated alkoxy, cyano group or nitro replaced

B represents hydrogen, alkyl or alkoxyalkyl, perhaps

A represents saturated or undersaturated, that do not replace or replace, optional at least one heteroatomic ring that contains with B with the carbon atom that they were connected,

D represents the following group that is selected from of hydrogen or optional replacement: alkyl, thiazolinyl, alkynyl, alkoxyalkyl, saturated or undersaturated cycloalkyl---and optional one or more annular atomses are by hetero atom replacement, aralkyl, aryl, heteroaryl alkyl or heteroaryl, perhaps in the described cycloalkyl

On behalf of A, D part, A be not substituted or substituted and optional at least one heteroatomic saturated or undersaturated ring that contains with the atom that D is connected separately with them, perhaps

A and Q ¹Representative is optional is together replaced by hydroxyl, perhaps by the optional alkyl that replaces separately, alkoxyl, alkylthio group, cycloalkyl, alkane two bases or alkene two bases that benzyloxy or aryl replaced, perhaps

Q ¹Represent hydrogen or alkyl,

Q ², Q ⁴, Q ⁵And Q ⁶Represent hydrogen or alkyl independently of one another,

Q ³Represent hydrogen, alkyl, alkoxyalkyl, alkylthio alkyl, the optional cycloalkyl that replaces (wherein optional methylene is by oxygen or sulfur) or the optional phenyl that replaces, perhaps

Q ³And Q ⁴Represent saturated or undersaturated, replacement or unsubstitutedly, optional contain a heteroatomic ring with the carbon atom that they connected,

G represents halogen or nitro;

With

(b) at least a compound that improves the crop compatibility that is selected from following compound:

4-dichloro-acetyl-1-oxa--4-azaspiro [4.5] decane (AD-67, MON-4660), 1-dichloro-acetyl-six hydrogen-3,3,8a-trimethyl pyrrolo-[1,2-a] pyrimidine-6 (2H)-ketone (dicyclonon, BAS-145138),

4-dichloro-acetyl-3,4-dihydro-3-methyl-2H-1,4-benzoxazine (benoxacor (benoxacor)),

5-chloroquinoline-8-ethoxyacetic acid-own the ester of 1-methyl (cloquitocet_mexyl (cloquintocet-mexyl) is referring to related compound among EP-A-86750, EP-A-94349, EP-A-191736, the EP-A-492366),

3-(2-chlorophenylmethyl)-1-(1-methyl isophthalic acid-phenylethyl) urea (cumyluron (cumyluron)),

α-(cyano group methoxyimino) benzene acetonitrile (cyometrinil (cyometrinil)),

The 2,4 dichloro benzene ethoxyacetic acid (2,4-D),

4-(2,4 dichloro benzene oxygen base) butyric acid (2,4-DB),

1-(1-methyl isophthalic acid-phenylethyl)-3-(4-aminomethyl phenyl) urea (vanilla swell (daimuron, dymron)),

3,6-two chloro-O-Anisic Acids (dicamba (dicamba)),

Piperidines-1-thiocarboxylic acid-S-1-methyl isophthalic acid-phenyl chlorocarbonate (dimepiperate (dimepiperate)),

2,2-two chloro-N-(2-oxo-2-(2-acrylic amino) ethyl)-N-(2-acrylic) acetamide (DKA-24),

2,2-two chloro-N, N-two-2-acrylic acetamide (dichlormide (dichlormid)),

4,6-two chloro-2-phenyl pyrimidines (fenclorim (fenclorim)),

1-(2,4 dichloro benzene base)-5-trichloromethyl-1H-1,2,4-triazole-3-carboxylic acid, ethyl ester (fenchlorazole (fenchlorazole-ethyl) is referring to related compound among EP-A-174562 and the EP-A-346620),

2-chloro-4-trifluoromethyl thiazole-5-carboxylic acid benzene methyl (separating careless amine (flurazole)),

4-chloro-N-(1,3-dioxolanes-2-base-methoxyl group)-α-trifluoroacetyl benzophenone oxime (fluxofenim (fluxofenim)),

3-dichloro-acetyl-5-(2-furyl)-2,2-Er Jia Ji oxazolidine (Xie Cao oxazole (furilazole), MON-13900),

4,5-dihydro-5,5-diphenyl-3-isoxazole carboxylic acid, ethyl ester (Shuan Ben oxazole acid (isoxadifen-ethyl) is referring to related compound among the WO-A-95/07897),

3,6-two chloro-O-Anisic Acid-1-(ethoxy carbonyl) ethyl esters (lactidichlor),

(4-chloro-neighbour-toloxyl) acetate (MCPA),

2-(4-chloro-neighbour-toloxyl) propionic acid (Vi par (mecoprop)),

1-(2,4 dichloro benzene base)-4,5-dihydro-5-methyl isophthalic acid H-pyrazoles-3,5-diethyl dicarboxylate (mefenpyrdiethyl (mefenpyr-diethyl) is referring to related compound among the WO-A-91/07874),

2-dichloromethyl-2-methyl isophthalic acid, 3-dioxolanes alkane (MG-191),

2-acrylic-1-oxa--4-azaspiro [4.5] decane-4-dithiocarboxylic esters (MG-838),

1, the 8-naphthalic anhydride,

α-(1,3-dioxolanes-2-base-methoxyimino) benzene acetonitrile (oxabetrinil (oxabetrinil)),

2,2-two chloro-N-(1,3-dioxolanes-2-base-methyl)-N-(2-acrylic) acetamide (PPG-1292),

3-dichloro-acetyl-2,2-Er Jia Ji oxazolidine (R-28725),

3-dichloro-acetyl-2,2,5-San Jia Ji oxazolidine (R-29148),

4-(4-chloro-neighbour-tolyl) butyric acid,

4-(4-chlorophenoxy) butyric acid,

The diphenylmethyl ethoxyacetic acid,

The diphenyl methoxy menthyl acetate,

Diphenylmethyl ethoxyacetic acid ethyl ester,

1-(2-chlorphenyl)-5-phenyl-1H-pyrazoles-3-carboxylate methyl ester,

1-(2,4 dichloro benzene base)-5-methyl isophthalic acid H-pyrazoles-3-carboxylic acid, ethyl ester,

1-(2,4 dichloro benzene base)-5-isopropyl-1H-pyrazoles-3-carboxylic acid, ethyl ester,

1-(2,4 dichloro benzene base)-5-(1, the 1-dimethyl ethyl)-1H-pyrazoles-3-carboxylic acid, ethyl ester,

1-(2,4 dichloro benzene base)-5-phenyl-1H-pyrazoles-3-carboxylic acid, ethyl ester (referring to related compound among EP-A-269806 and the EP-A-333131),

5-(2,4 dichloro benzene methyl)-2-isoxazoline-3-carboxylic acid, ethyl ester,

5-phenyl-2-isoxazoline-3-carboxylic acid, ethyl ester,

5-(4-fluorophenyl)-5-phenyl-2-isoxazoline-3-carboxylic acid, ethyl ester (referring to related compound among the WO-A-91/08202),

5-chloroquinoline-8-ethoxyacetic acid-1,3-dimethyl butyrate-1-base ester,

5-chloroquinoline-8-ethoxyacetic acid-4-allyloxy butyl ester,

5-chloroquinoline-8-ethoxyacetic acid-1-allyloxy third-2-base ester,

5-chloro-quinoxaline-8-ethoxyacetic acid methyl esters,

5-chloroquinoline-8-ethoxyacetic acid ethyl ester,

5-chloro-quinoxaline-8-ethoxyacetic acid allyl ester,

5-chloroquinoline-8-ethoxyacetic acid-2-oxo third-1-base ester,

5-chloroquinoline-8-oxygen propylmalonic acid diethylester,

5-chloro-quinoxaline-8-oxygen propylmalonic acid diallyl,

5-chloroquinoline-8-oxygen propylmalonic acid diethylester (referring to related compound among the EP-A-582198),

4-carboxyl benzodihydropyran-4-guanidine-acetic acid (AC-304415 is referring to EP-A-613618),

The 4-tomatotone,

3,3 '-dimethyl-4-methoxyl group benzophenone,

1-bromo-4-chloromethyl sulfonyl benzene,

1-[4-(N-2-methoxybenzoyl base sulfamoyl) phenyl]-3-methyl urea (being N-(2-methoxybenzoyl base)-4-[(methylamino carbonyl) amino] benzsulfamide),

1-[4-(N-2-methoxybenzoyl base sulfamoyl) phenyl]-3, the 3-dimethyl urea,

1-[4-(N-4,5-dimethylbenzoyl sulfamoyl) phenyl]-3-methyl urea,

1-[4-(N-naphthyl sulfamoyl) phenyl]-3, the 3-dimethyl urea,

N-(2-methoxyl group-5-methyl benzoyl)-4-(cyclopropyl amino carbonyl) benzsulfamide,

One of and/or following compound by general formula definition,

General formula (IIa)

Or general formula (IIb)

Or general formula (IIc)

Wherein

M represents numeral 0,1,2,3,4 or 5,

A ¹Represent one of divalent heterocyclic group shown below

N represents numeral 0,1,2,3,4 or 5,

A ²Representative is optional by C ₁-C ₄Alkyl and/or C ₁-C ₄Alkoxy carbonyl and/or C ₁-C ₄Two bases of the alkane with 1 or 2 carbon atom that allyloxycarbonyl replaces,

R ⁸Representation hydroxy, sulfydryl, amino, C ₁-C ₆Alkoxyl, C ₁-C ₆Alkylthio group, C ₁-C ₆Alkyl amino or two-(C ₁-C ₄Alkyl) amino,

R ⁹Representation hydroxy, sulfydryl, amino, C ₁-C ₇Alkoxyl, C ₁-C ₆Alkene oxygen base, C ₁-C ₆Alkene oxygen base-C ₁-C ₆Alkoxyl, C ₁-C ₆Alkylthio group, C ₁-C ₆Alkyl amino or two-(C ₁-C ₄Alkyl) amino,

R ¹⁰The optional separately C that is replaced by fluorine, chlorine and/or bromine of representative ₁-C ₄Alkyl,

R ¹¹Represent hydrogen, perhaps the optional separately C that is replaced by fluorine, chlorine and/or bromine of representative ₁-C ₆Alkyl, C ₂-C ₆Thiazolinyl or C ₂-C ₆Alkynyl, C ₁-C ₄Alkoxy-C ₁-C ₄Alkyl, dioxolanyl-C ₁-C ₄Alkyl, furyl, furyl-C ₁-C ₄Alkyl, thienyl, thiazolyl, piperidyl, perhaps representative is optional by fluorine, chlorine and/or bromine or C ₁-C ₄The phenyl that alkyl replaces,

R ¹²Represent hydrogen, perhaps the optional separately C that is replaced by fluorine, chlorine and/or bromine of representative ₁-C ₆Alkyl, C ₂-C ₆Thiazolinyl or C ₂-C ₆Alkynyl, C ₁-C ₄Alkoxy-C ₁-C ₄Alkyl, dioxolanyl-C ₁-C ₄Alkyl, furyl, furyl-C ₁-C ₄Alkyl, thienyl, thiazolyl, piperidyl, perhaps representative is optional by fluorine, chlorine and/or bromine or C ₁-C ₄The phenyl that alkyl replaces, perhaps

R ¹¹And R ¹²Representative is optional separately by C together ₁-C ₄Alkyl, phenyl, furyl, fused benzene rings or the C that is replaced by following two substituting groups ₃-C ₆Alkane two bases or C ₂-C ₅Oxa-alkane two bases, described two substituting groups form 5 or 6 yuan of carbocyclic rings with the C atom that they connected,

R ¹³Represent hydrogen, cyano group, halogen, perhaps the optional separately C that is replaced by fluorine, chlorine and/or bromine of representative ₁-C ₄Alkyl, C ₃-C ₆Cycloalkyl or phenyl,

R ¹⁴Represent hydrogen, perhaps representative is optional by hydroxyl, cyano group, halogen or C ₁-C ₄The C that alkoxyl replaces ₁-C ₆Alkyl, C ₃-C ₆Cycloalkyl or three-(C ₁-C ₄Alkyl) silicyl,

R ¹⁵Represent hydrogen, cyano group, halogen, perhaps the optional separately C that is replaced by fluorine, chlorine and/or bromine of representative ₁-C ₄Alkyl, C ₃-C ₆Cycloalkyl or phenyl,

X ¹Represent nitro, cyano group, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Halogenated alkoxy,

X ²Represent hydrogen, cyano group, nitro, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Halogenated alkoxy,

X ³Represent hydrogen, cyano group, nitro, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Halogenated alkoxy,

And/or following compound by the general formula definition,

General formula (IId)

Or general formula (IIe)

Wherein

T represents numeral 0,1,2,3,4 or 5,

V represents numeral 0,1,2,3,4 or 5,

R ¹⁶Represent hydrogen or C ₁-C ₄Alkyl,

R ¹⁷Represent hydrogen or C ₁-C ₄Alkyl,

R ¹⁸Represent hydrogen, perhaps representative is optional separately by cyano group, halogen or C ₁-C ₄The C that alkoxyl replaces ₁-C ₆Alkyl, C ₁-C ₆Alkoxyl, C ₁-C ₆Alkylthio group, C ₁-C ₆Alkyl amino or two-(C ₁-C ₄Alkyl) amino, perhaps representative is optional separately by cyano group, halogen or C ₁-C ₄The C that alkyl replaces ₃-C ₆Cycloalkyl, C ₃-C ₆Cycloalkyl oxy, C ₃-C ₆Cycloalkyl sulfenyl or C ₃-C ₆Cycloalkyl amino,

R ¹⁹Represent hydrogen, perhaps representative is optional by cyano group, hydroxyl, halogen or C ₁-C ₄The C that alkoxyl replaces ₁-C ₆Alkyl, perhaps representative is optional separately by the C of cyano group or halogen replacement ₃-C ₆Thiazolinyl or C ₃-C ₆Alkynyl, perhaps representative is optional by cyano group, halogen or C ₁-C ₄The C that alkyl replaces ₃-C ₆Cycloalkyl,

R ²⁰Represent hydrogen, perhaps representative is optional by cyano group, hydroxyl, halogen or C ₁-C ₄The C that alkoxyl replaces ₁-C ₆Alkyl, perhaps representative is optional separately by the C of cyano group or halogen replacement ₃-C ₆Thiazolinyl or C ₃-C ₆Alkynyl, perhaps representative is optional by cyano group, halogen or C ₁-C ₄The C that alkyl replaces ₃-C ₆Cycloalkyl, perhaps representative is optional by nitro, cyano group, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄The phenyl that halogenated alkoxy replaces is perhaps with R ¹⁹Representative is optional separately by C together ₁-C ₄The C that alkyl replaces ₂-C ₆Alkane two bases or C ₂-C ₅Oxa-alkane two bases,

X ⁴Represent nitro, cyano group, carboxyl, carbamoyl, formoxyl, amino-sulfonyl, hydroxyl, amino, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Halogenated alkoxy, and

X ⁵Represent nitro, cyano group, carboxyl, carbamoyl, formoxyl, amino-sulfonyl, hydroxyl, amino, halogen, C ₁-C ₄Alkyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Halogenated alkoxy.

In above-mentioned definition, hydrocarbon chain, for example alkyl or alkane two bases comprise and heteroatomic combination, alkoxyl for example all can be respectively a straight chain or have side chain.

In its various character, formula (I) compound is main according to substituent character, can how much and/or the form of optical isomer exist, perhaps the form of the isomer mixture of forming with difference exists, and can separate by conventional methods if described mixture is suitable.The invention provides pure isomer and isomer mixture, and uses thereof and contain their composition.Yet, for for simplicity, in various situations, only claim formula (I) compound, but its implication had both referred to pure compound, and if the suitable mixture of isomers that also refers to different proportion.

The implication (1) of considering the CDC group obtains following basic structure (I-1) to (I-6) to (6):

Wherein,

A, B, D, G, Q ¹, Q ², Q ³, Q ⁴, Q ⁵, Q ⁶, W, X, Y and Z definition as above.

Formula (I) provides the broad definition of cyclic dicarbonyl compounds of the replacement of desinsection and/or miticide composition.More than reach preferred substituents or the following elaboration of group range in the structural formula proposed below:

W and Z preferably represent hydrogen, halogen, C independently of one another ₁-C ₆Alkyl, C ₁-C ₆Haloalkyl or C ₁-C ₆Alkoxyl,

X preferably represents halogen, C ₁-C ₆Alkyl, C ₂-C ₆Thiazolinyl, C ₂-C ₆Alkynyl, C ₁-C ₆Haloalkyl, C ₁-C ₆Alkoxyl, C ₃-C ₆Alkene oxygen base, C ₁-C ₆Halogenated alkoxy, C ₃-C ₆Haloalkene oxygen base, nitro or cyano group,

Y preferably represents hydrogen, halogen, C ₁-C ₄Alkyl, C ₁-C ₂Haloalkyl, C ₁-C ₂One of halogenated alkoxy, cyano group or following group

Wherein,

V ¹Preferred hydrogen, halogen, the C of representing ₁-C ₁₂Alkyl, C ₁-C ₆Alkoxyl, C ₁-C ₄Haloalkyl, C ₁-C ₄Halogenated alkoxy, nitro or cyano group,

V ²And V ³Preferably represent hydrogen, halogen, C independently of one another ₁-C ₆Alkyl, C ₁-C ₆Alkoxyl, C ₁-C ₄Haloalkyl or C ₁-C ₄Halogenated alkoxy,

CDC preferably represents one of following group

A preferably represents hydrogen, perhaps chooses the C of halo separately wantonly ₁-C ₁₂Alkyl, C ₃-C ₈Thiazolinyl, C ₁-C ₁₀Alkoxy-C ₁-C ₈Alkyl, C ₁-C ₁₀Alkylthio group-C ₁-C ₆Alkyl, optional by halogen, C ₁-C ₆Alkyl or C ₁-C ₆Alkoxyl replaces wherein optional one or two not the annular atoms of direct neighbor by the C of oxygen and/or sulfur ₃-C ₈Cycloalkyl, perhaps representative is optional separately by halogen, C ₁-C ₆Alkyl, C ₁-C ₆Haloalkyl, C ₁-C ₆Alkoxyl, C ₁-C ₆Phenyl or phenyl-C that halogenated alkoxy, cyano group or nitro replace ₁-C ₆Alkyl,

B preferably represents hydrogen, C ₁-C ₁₂Alkyl or C ₁-C ₈Alkoxy-C ₁-C ₆Alkyl, perhaps

A, B preferably represent a wherein optional annular atoms by oxygen or sulfur and optional by C with the carbon atom that they connected ₁-C ₈Alkyl, C ₃-C ₁₀Cycloalkyl, C ₁-C ₈Haloalkyl, C ₁-C ₈Alkoxyl, C ₁-C ₈Alkylthio group, halogen or phenyl list replace or dibasic saturated C ₃-C ₁₀Cycloalkyl or undersaturated C ₅-C ₁₀Cycloalkyl, perhaps

A, B preferably represent the C that is replaced by alkylene two bases, alkylene dioxo base or alkylene disulfide group with the carbon atom that they connected ₅-C ₆Cycloalkyl, described alkylene two bases are optional by C ₁-C ₄Alkyl replaces and optional one or two the not oxygen and/or sulphur atom of direct neighbor that contain, and described alkylene dioxo base or alkylene disulfide group and coupled carbon atom form another together five to octatomic ring, perhaps

A, B preferably represent C with the carbon atom that they connected ₃-C ₈Cycloalkyl or C ₅-C ₈Cycloalkenyl group, wherein two substituting groups are represented optional separately by C with the carbon atom that is connected with them separately ₁-C ₆Alkyl, C ₁-C ₆Wherein optional methylene that alkoxy or halogen replaces is by the C of oxygen or sulfur ₂-C ₆Alkane two bases, C ₂-C ₆Alkene two bases or C ₄-C ₆Alkane diene two bases,

D preferably represents hydrogen, and representative is the C of optional halo separately ₁-C ₁₂Alkyl, C ₃-C ₈Thiazolinyl, C ₃-C ₈Alkynyl, C ₁-C ₁₀Alkoxy-C ₂-C ₈Alkyl, optional by halogen, C ₁-C ₄Alkyl, C ₁-C ₄Alkoxyl or C ₁-C ₄Wherein optional annular atoms that haloalkyl replaces is by the C of oxygen or sulfur ₃-C ₈Cycloalkyl, perhaps optional separately by halogen, C ₁-C ₆Alkyl, C ₁-C ₆Haloalkyl, C ₁-C ₆Alkoxyl, C ₁-C ₆Phenyl or phenyl-C that halogenated alkoxy, cyano group or nitro replace ₁-C ₆Alkyl,

A and D preferably represent the optional separately C that replaces together ₃-C ₆Alkane two bases or C ₃-C ₆Alkene two bases are wherein chosen a methylene wantonly by carbonyl, oxygen or sulfur,

Suitable substituting group is respectively:

Halogen, hydroxyl, the C of sulfydryl or optional separately halo ₁-C ₁₀Alkyl or C ₁-C ₆Alkoxyl, perhaps another C ₃-C ₆Alkane two bases, C ₃-C ₆Alkene two bases or butadienyl, described another C ₃-C ₆Alkane two bases, C ₃-C ₆Alkene two bases or butadienyl are optional by C ₁-C ₆Alkyl replacement or wherein optional two adjacent substituting groups form another with the carbon atom that is connected separately with them and can contain saturated or unsaturated ring aerobic or sulphur, that have 5 or 6 annular atomses (when for formula (I-1) compound, A preferably represents with the atom that they were connected with D, for example, following A D-1 to AD-10 group)

A and Q ¹Preferred together representative is optional separately to be replaced by identical or different following substituting group list or dibasic and pass through C ₁-C ₂Alkane two base or the C by the oxygen atom bridging ₃-C ₆Alkane two bases or C ₄-C ₆Alkene two bases, described substituting group is selected from halogen, chooses wantonly by identical or different halogen list separately to replace to trisubstituted C ₁-C ₁₀Alkyl, C ₁-C ₆Alkoxyl, C ₁-C ₆Alkylthio group, C ₃-C ₇Cycloalkyl, and optional separately by identical or different halogen, the C of being selected from ₁-C ₆Alkyl and C ₁-C ₆The substituting group list of alkoxyl replaces to trisubstituted benzyloxy and phenyl, perhaps

Q ¹Preferred hydrogen or the C of representing ₁-C ₄Alkyl,

Q ², Q ⁴, Q ⁵And Q ⁶Preferably represent hydrogen or C independently of one another ₁-C ₄Alkyl,

Q ³The preferred hydrogen, C represented ₁-C ₆Alkyl, C ₁-C ₆Alkoxy-C ₁-C ₂Alkyl, C ₁-C ₆Alkylthio group-C ₁-C ₂Alkyl, optional by halogen, C ₁-C ₄Alkyl or C ₁-C ₄Wherein optional methylene that alkoxyl replaces is by the C of oxygen or sulfur ₃-C ₈Cycloalkyl, perhaps representative is optional by halogen, C ₁-C ₄Alkyl, C ₁-C ₄Alkoxyl, C ₁-C ₂Haloalkyl, C ₁-C ₂The phenyl that halogenated alkoxy, cyano group or nitro replace, perhaps

Q ³And Q ⁴Preferably represent optional by C with the carbon atom that they connected ₁-C ₄Alkyl, C ₁-C ₄Alkoxyl or C ₁-C ₂The C that haloalkyl replaces ₃-C ₇Ring is wherein chosen an annular atoms wantonly by oxygen or sulfur,

G preferably represents chlorine, bromine or nitro.

In as the preferred group definition that proposes, halogen is represented fluorine, chlorine, bromine and iodine, particularly fluorine, chlorine and bromine.

W and Z especially preferably represent hydrogen, chlorine, bromine, C independently of one another ₁-C ₃Alkyl or C ₁-C ₃Alkoxyl,

X especially preferably represents chlorine, bromine, C ₁-C ₄Alkyl, C ₁-C ₄Alkoxyl, C ₁-C ₃Haloalkyl, C ₁-C ₃Halogenated alkoxy or cyano group,

Y especially preferably represents hydrogen, chlorine, bromine, C ₁-C ₂Alkyl, trifluoromethyl or represent following groups

V ¹Especially preferably represent hydrogen, fluorine, chlorine, bromine, C ₁-C ₆Alkyl, C ₁-C ₄Alkoxyl, C ₁-C ₂Haloalkyl, C ₁-C ₂Halogenated alkoxy, nitro or cyano group,

V ²Especially preferably represent hydrogen, fluorine, chlorine, bromine, C ₁-C ₄Alkyl, C ₁-C ₄Alkoxyl, C ₁-C ₂Haloalkyl or C ₁-C ₂Halogenated alkoxy,

CDC especially preferably represents one of following group

A especially preferably represents hydrogen, and representative is optional separately to be replaced to trisubstituted C by the fluorine or chlorine list ₁-C ₆Alkyl, C ₁-C ₄Alkoxy-C ₁-C ₂Alkyl, perhaps representative is optional by fluorine, chlorine, C ₁-C ₂Alkyl or C ₁-C ₂The alkoxyl list replaces or dibasic C ₃-C ₇Cycloalkyl,

B especially preferably represents hydrogen or C ₁-C ₆Alkyl, perhaps

A, B wherein choose an annular atoms wantonly by oxygen or sulfur and optional by C with the preferred especially representative of the carbon atom that they connected ₁-C ₄Alkyl, C ₁-C ₂Haloalkyl or C ₁-C ₄The mono-substituted saturated C of alkoxyl ₃-C ₇Cycloalkyl, condition are Q ³Especially preferably represent hydrogen or methyl, perhaps

A, B represent by the C of alkylene two bases or alkylene dioxo base replacement with the carbon atom that they connected is preferred especially ₅-C ₆Cycloalkyl, described alkylene two bases are optional to contain one or two the not oxygen of direct neighbor or sulphur atoms and optionally replaced by methyl or ethyl, described alkylene dioxo base and the carbon atom that is connected with it form another five or hexatomic ring, condition is Q ³Especially preferably represent hydrogen or methyl, perhaps

A, B especially preferably represent C with the carbon atom that they connected ₃-C ₆Cycloalkyl or C ₅-C ₆Cycloalkenyl group, wherein two substituting groups are represented optional C that methylene is replaced by oxo with the carbon atom that is connected with them separately ₂-C ₄Alkane two bases, C ₂-C ₄Alkene two bases are perhaps represented butadiene two bases, and described butadiene two bases are optional separately to be replaced by the methyl or methoxy list, and condition is Q ³Especially preferably represent hydrogen or methyl,

D especially preferably represents hydrogen, and representative is optional separately to be replaced to trisubstituted C by the fluorine or chlorine list ₁-C ₆Alkyl, C ₃-C ₆Thiazolinyl, C ₁-C ₄Alkoxy-C ₂-C ₃Alkyl, representative is optional by C ₁-C ₂Alkyl, C ₁-C ₂Alkoxyl or trifluoromethyl are mono-substituted and wherein choose a methylene wantonly by the C of oxygen or sulfur ₃-C ₇Cycloalkyl, perhaps when not being formula (I-1) compound (but) representative is optional separately by fluorine, chlorine, bromine, C ₁-C ₄Alkyl, C ₁-C ₂Haloalkyl, C ₁-C ₄Alkoxyl or C ₁-C ₂The halogenated alkoxy list replaces or dibasic phenyl, pyridine radicals or benzyl, perhaps

A and D especially preferably represent one of them methylene can be by the C that replaces oxygen or sulfur, optional together ₃-C ₅Alkane two bases, possible substituting group are C ₁-C ₂Alkyl, perhaps

A especially preferably represents one of group AD-1 to AD-10 with D (when for formula (I-1) compound) with the atom that they are connected separately:

A and Q ¹The optional separately C that is selected from of preferred especially together representative ₁-C ₂Alkyl and C ₁-C ₂The identical or different substituting group list of alkoxyl replaces or dibasic C ₃-C ₄Alkane two bases or C ₃-C ₄Alkene two bases, perhaps

Q ¹Especially preferably represent hydrogen,

Q ²Especially preferably represent hydrogen,

Q ⁴, Q ⁵And Q ⁶Especially preferably represent hydrogen or C independently of one another ₁-C ₂Alkyl,

Q ³Especially preferably represent hydrogen, C ₁-C ₄Alkyl, C ₁-C ₄Alkoxy-C ₁-C ₂Alkyl, C ₁-C ₄Alkylthio group-C ₁-C ₂Alkyl, perhaps optional wherein optional methylene that is replaced by methyl or methoxy is by the C of oxygen or sulfur ₃-C ₆Cycloalkyl, perhaps

Q ³And Q ⁴Optional with the preferred especially representative of the carbon atom that they connected by C ₁-C ₄Alkyl or C ₁-C ₄The replacement of alkoxyl list or dibasic and wherein optional annular atoms are by the saturated C of oxygen or sulfur ₅-C ₆Ring,

Condition is that A especially preferably represents hydrogen or methyl,

G especially preferably represents chlorine or nitro.

In as the preferred especially group definition that proposes, halogen is represented fluorine, chlorine, bromine and iodine, particularly fluorine, chlorine and bromine.

W and Z especially preferably represent hydrogen, chlorine, bromine, methyl, ethyl, methoxy or ethoxy in earth polar independently of one another,

X extremely especially preferably represents chlorine, bromine, methyl, ethyl, propyl group, methoxyl group, ethyoxyl, trifluoromethyl, difluoro-methoxy, trifluoromethoxy or cyano group,

Y extremely especially preferably represents hydrogen, chlorine, bromine, methyl, trifluoromethyl or represents following groups

V ¹Extremely especially preferably represent hydrogen, fluorine, chlorine, bromine, methyl, ethyl, the tert-butyl group, methoxyl group, trifluoromethyl or trifluoromethoxy,

V ²Extremely especially preferably represent hydrogen, fluorine, chlorine, methyl, methoxyl group or trifluoromethyl,

One of following group of the preferred extremely especially representative of CDC

A extremely especially preferably represents hydrogen, and representative is optional separately to be replaced to trisubstituted C by the fluorine list ₁-C ₄Alkyl or C ₁-C ₂Alkoxy-C ₁-C ₂Alkyl, perhaps representative is optional by fluorine, the mono-substituted C of methyl or methoxy ₃-C ₆Cycloalkyl,

B extremely especially preferably represents hydrogen, methyl or ethyl, perhaps

A, B are replaced by oxo with the wherein optional annular atoms of the preferred extremely especially representative of the carbon atom that they connected and are optional by the mono-substituted saturated C of methyl, trifluoromethyl, methoxyl group, ethyoxyl, propoxyl group, butoxy or isobutoxy ₅-C ₆Cycloalkyl, condition are Q ³Extremely especially preferably represent hydrogen, perhaps

A, B are contained two not C of the alkylene dioxo base replacement of the oxygen atom of direct neighbor with the preferred extremely especially representative of the carbon atom that they connected ₅-C ₆Cycloalkyl, condition are Q ³Extremely especially preferably represent hydrogen,

D extremely especially preferably represents hydrogen, and representative is optional separately to be replaced to trisubstituted C by the fluorine list ₁-C ₄Alkyl, C ₃-C ₄Thiazolinyl, C ₁-C ₂Alkoxy-C ₂-C ₃Alkyl or wherein optional methylene are by the C of oxygen or sulfur ₃-C ₆Cycloalkyl, perhaps when not being formula (I-1) compound (but) representative is optional is separately replaced or dibasic phenyl or pyridine radicals by fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl, isopropyl, methoxyl group, ethyoxyl, trifluoromethyl or trifluoromethoxy list, perhaps

The wherein optional carbon atom of the preferred extremely especially together representative of A and D is by oxygen or sulfur and optional the replacement by the methyl list or dibasic, the optional C that replaces ₃-C ₅Alkane two bases, perhaps

A extremely especially preferably represents group with D (when for formula (I-1) compound) with the atom that they are connected separately:

A and Q ¹Preferred extremely especially together representative is optional to be replaced or dibasic C by the methyl or methoxy list ₃-C ₄Alkane two bases, perhaps

Q ¹Extremely especially preferably represent hydrogen,

Q ²Extremely especially preferably represent hydrogen,

Q ⁴, Q ⁵And Q ⁶Hydrogen or methyl are especially preferably represented in earth polar independently of one another,

Q ³Extremely especially preferably represent hydrogen, methyl, ethyl or C ₃-C ₆Cycloalkyl, perhaps

Q ³And Q ⁴With the preferred extremely especially representative of carbon atom that they connected optional by methyl or methoxy mono-substituted and wherein optional annular atoms by the saturated C of oxygen or sulfur ₅-C ₆Ring, condition is that A extremely especially preferably represents hydrogen,

G extremely especially preferably represents chlorine or nitro,

W especially preferably represents hydrogen, chlorine, bromine, methyl, ethyl, methoxy or ethoxy,

X especially preferably represents chlorine, bromine, methyl, ethyl, propyl group, methoxyl group, ethyoxyl, trifluoromethyl, difluoro-methoxy, trifluoromethoxy or cyano group,

Y especially preferably represents hydrogen, chlorine, bromine, methyl, trifluoromethyl or represents following groups

V ¹Especially preferably represent hydrogen, fluorine, chlorine, bromine, methyl, ethyl, the tert-butyl group, methoxyl group, trifluoromethyl or trifluoromethoxy,

V ²Especially preferably represent hydrogen, fluorine, chlorine, methyl, methoxyl group or trifluoromethyl,

Z especially preferably represents hydrogen, methyl, chlorine or bromine,

CDC especially preferably represents one of following group

A especially preferably represents hydrogen, and representative is optional separately to be replaced to trisubstituted C by the fluorine list ₁-C ₄Alkyl or C ₁-C ₂Alkoxy-C ₁-C ₂Alkyl, perhaps representative is optional by fluorine, the mono-substituted C of methyl or methoxy ₃-C ₆Cycloalkyl,

B especially preferably represents hydrogen, methyl or ethyl, perhaps

A, B are replaced by oxo with the wherein optional annular atoms of the especially preferred representative of the carbon atom that they connected and are optional by the mono-substituted saturated C of methyl, trifluoromethyl, methoxyl group, ethyoxyl, propoxyl group, butoxy or isobutoxy ₅-C ₆Cycloalkyl,

D especially preferably represents hydrogen,

G especially preferably represents chlorine.

Above-mentioned wide in range or preferred group definition or explanation be combination with one another as required, promptly comprises the combination between each scope and the preferable range.

The present invention preferably uses formula (I) compound of the combination that comprises above-mentioned preferred (preferably) implication.

The present invention especially preferably uses formula (I) compound of the combination that comprises above-mentioned special preferred meaning.

Preferred extremely especially formula (I) compound that uses the combination that comprises above-mentioned extremely special preferred meaning of the present invention.

The present invention especially preferably uses formula (I) compound of the combination that comprises above-mentioned especially preferred meaning.

Saturated or unsaturated alkyl, for example alkyl, alkylene two bases or thiazolinyl comprise and heteroatomic combination, alkoxyl for example all can be respectively straight chain within the bounds of possibility or have side chain.

Except as otherwise noted, the optional group that replaces can be single replacement or polysubstituted, and wherein under polysubstituted situation, substituting group can be identical or different.

The compound that in embodiment, proposes, also can propose especially with following formula (I-1) compound:

Table 1:W=CH ₃, X=CH ₃, Y=4-CH ₃, Z=H

Table 2:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝4-Cl；Z＝H；

Table 3:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝4-Br；Z＝H；

Table 4:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝CH ₃；Y＝4-Cl；Z＝H；

Table 5:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝CH ₃；Y＝4-Br；Z＝H；

Table 6:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝C ₂H ₅；Y＝4-Cl；Z＝H；

Table 7:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝C ₂H ₅；Y＝4-Br；Z＝H；

Table 8:A, B and D are as described in Table 1

W＝CH ₃；X＝Cl；Y＝4-Cl；Z＝H；

Table 9:A, B and D are as described in Table 1

W＝CH ₃；X＝Br；Y＝4-Br；Z＝H；

Table 10:A, B and D are as described in Table 1

W＝CH ₃；X＝Cl；Y＝4-Br；Z＝H；

Table 11:A, B and D are as described in Table 1

W＝CH ₃；X＝Br；Y＝4-Cl；Z＝H；

Table 12:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Cl；Y＝4-Cl；Z＝H；

Table 13:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Br；Y＝4-Br；Z＝H；

Table 14:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Cl；Y＝4-Br；Z＝H；

Table 15:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Br；Y＝4-Cl；Z＝H；

Table 16:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝H；Z＝H；

Table 17:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝H；Z＝H；

Table 18:A, B and D are as described in Table 1

W＝H；X＝Br；Y＝H；Z＝H；

Table 19:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝4-Cl；Z＝H；

Table 20:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝4-CH ₃；Z＝H；

Table 21:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝4-CH ₃；Z＝H；

Table 22:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝4-Cl；Z＝H；

Table 23:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝4-Br；Z＝H；

Table 24:A, B and D are as described in Table 1

W＝CH ₃；X＝Cl；Y＝4-CH ₃；Z＝H；

Table 25:A, B and D are as described in Table 1

W＝CH ₃；X＝Br；Y＝4-CH ₃；Z＝H；

Table 26:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Cl；Y＝4-CH ₃；Z＝H；

Table 27:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝Br；Y＝4-CH ₃；Z＝H；

Table 28:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝CH ₃；Y＝4-CH ₃；Z＝H；

Table 29:A, B and D are as described in Table 1

W＝C ₂H ₅；X＝C ₂H ₅；Y＝4-CH ₃；Z＝H；

Table 30:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝4-CH ₃；Z＝5-CH ₃.

Table 31:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝4-Cl；Z＝5-CH ₃.

Table 32:A, B and D are as described in Table 1

W＝H；X＝Br；Y＝4-CH ₃；Z＝5-CH ₃.

Table 33:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝4-Cl；Z＝5-CH ₃.

Table 34:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝4-Br；Z＝5-CH ₃.

Table 35:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝4-CH ₃；Z＝5-Cl.

Table 36:A, B and D are as described in Table 1

W＝H；X＝CH ₃；Y＝H；Z＝5-CH ₃.

Table 37:A, B and D are as described in Table 1

W＝H；X＝Cl；Y＝H；Z＝5-CH ₃.

Table 38:A, B and D are as described in Table 1

W＝H；X＝Br；Y＝H；Z＝5-CH ₃.

Table 39:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝4-CH ₃；Z＝3-CH ₃.

Table 40:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝4-CH ₃；Z＝3-Cl，

Table 41:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝4-CH ₃；Z＝3-Br.

Table 42:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝H；Z＝3-Cl.

Table 43:A, B and D are as described in Table 1

W＝CH ₃；X＝CH ₃；Y＝H；Z＝3-Br.

Formula (I) compound is known from the disclosed patent documentation that introductory song is quoted basically, and perhaps they can be by the method preparation of describing in the described patent documentation.

The preferred meaning of the above-mentioned group that with the formula of improving the crop compatibility (IIa), (IIb), (IIc), (IId) and (IIe) compound (" herbicide-safener ") is relevant is defined as follows.

M preferably represents numeral 0,1,2,3 or 4.

A ¹One of preferred representative divalent heterocyclic group shown below

N preferably represents numeral 0,1,2,3 or 4.

A ²Optional separately methylene or the ethylidene that is replaced by methyl, ethyl, methoxycarbonyl group, carbethoxyl group or allyloxy carbonyl of preferred representative.

R ⁸Preferred representation hydroxy, sulfydryl, amino, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, n-butoxy, isobutoxy, sec-butoxy or tert-butoxy, methyl mercapto, ethylmercapto group, positive rosickyite base or different rosickyite base, positive butylthio, isobutyl sulfenyl, secondary butylthio or uncle's butylthio, methylamino, ethylamino, n-pro-pyl amino or isopropyl amino, normal-butyl amino, isobutylamino, sec-butyl amino or tert-butyl group amino, dimethylamino or diethylamino.

R ⁹Preferred representation hydroxy, sulfydryl, amino, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, n-butoxy, isobutoxy, sec-butoxy or tert-butoxy, the own oxygen base of 1-methyl, allyloxy, 1-allyloxy methyl-ethyoxyl, methyl mercapto, ethylmercapto group, positive rosickyite base or different rosickyite base, positive butylthio, the isobutyl sulfenyl, secondary butylthio or uncle's butylthio, methylamino, ethylamino, n-pro-pyl amino or isopropyl amino, normal-butyl amino, isobutylamino, sec-butyl amino or tert-butyl group amino, dimethylamino or diethylamino.

R ¹⁰Optional separately methyl, ethyl, n-pro-pyl or the isopropyl that is replaced by fluorine, chlorine and/or bromine of preferred representative.

R ¹¹The preferred hydrogen of representing, optional separately by the methyl of fluorine and/or chlorine replacement, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, the sec-butyl or the tert-butyl group, acrylic, cyclobutenyl, propinyl or butynyl, methoxy, ethoxyl methyl, methoxy ethyl, ethoxyethyl group, the dioxolanes ylmethyl, furyl, furyl methyl, thienyl, thiazolyl, piperidyl, or it is optional by fluorine, chlorine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, the phenyl that the sec-butyl or the tert-butyl group replace.

R ¹²The preferred hydrogen, optional by methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, acrylic, cyclobutenyl, propinyl or butynyl, methoxy, ethoxyl methyl, methoxy ethyl, ethoxyethyl group, dioxolanes ylmethyl, furyl, furyl methyl, thienyl, thiazolyl, the piperidyl of fluorine and/or chlorine replacement separately of representing, or the optional phenyl that is replaced by fluorine, chlorine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, perhaps with R ¹¹Optional group-the CH that is replaced by methyl, ethyl, furyl, phenyl, fused benzene rings or replaced by two substituting groups of representative together ₂-O-CH ₂-CH ₂-and-CH ₂-CH ₂-O-CH ₂-CH ₂One of-, described two substituting groups form 5 or 6 yuan of carbocyclic rings with the C atom that is connected with them.

R ¹³Preferred hydrogen, cyano group, fluorine, chlorine, the bromine represented, perhaps optional separately methyl, ethyl, n-pro-pyl or isopropyl, cyclopropyl, cyclobutyl, cyclopenta, cyclohexyl or the phenyl that is replaced by fluorine, chlorine and/or bromine of representative.

R ¹⁴Preferred hydrogen, optional methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group that is replaced by hydroxyl, cyano group, fluorine, chlorine, methoxyl group, ethyoxyl, positive propoxy or isopropoxy represented.

R ¹⁵Preferred hydrogen, cyano group, fluorine, chlorine, the bromine represented, perhaps optional separately methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, cyclopropyl, cyclobutyl, cyclopenta, cyclohexyl or the phenyl that is replaced by fluorine, chlorine and/or bromine of representative.

X ¹Preferred nitro, cyano group, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, difluoromethyl, dichloromethyl, trifluoromethyl, trichloromethyl, a chlorodifluoramethyl-, a fluorine dichloromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, difluoro-methoxy or the trifluoromethoxy represented.

X ²Preferred hydrogen, nitro, cyano group, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, difluoromethyl, dichloromethyl, trifluoromethyl, trichloromethyl, a chlorodifluoramethyl-, a fluorine dichloromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, difluoro-methoxy or the trifluoromethoxy represented.

X ³Preferred hydrogen, nitro, cyano group, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, difluoromethyl, dichloromethyl, trifluoromethyl, trichloromethyl, a chlorodifluoramethyl-, a fluorine dichloromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, difluoro-methoxy or the trifluoromethoxy represented.

T preferably represents numeral 0,1,2,3 or 4.

V preferably represents numeral 0,1,2,3 or 4.

R ¹⁶Preferred hydrogen, methyl, ethyl, n-pro-pyl or the isopropyl represented.

R ¹⁷Preferred hydrogen, methyl, ethyl, n-pro-pyl or the isopropyl represented.

R ¹⁸The preferred hydrogen of representing, optional separately by cyano group, fluorine, chlorine, methoxyl group, ethyoxyl, the methyl that positive propoxy or isopropoxy replace, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, the sec-butyl or the tert-butyl group, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, n-butoxy, isobutoxy, sec-butoxy or tert-butoxy, methyl mercapto, ethylmercapto group, positive rosickyite base or different rosickyite base, positive butylthio, the isobutyl sulfenyl, secondary butylthio or uncle's butylthio, methylamino, ethylamino, n-pro-pyl amino or isopropyl amino, normal-butyl amino, isobutylamino, sec-butyl amino or tert-butyl group amino, dimethylamino or diethylamino, or it is optional separately by cyano group, fluorine, chlorine, bromine, methyl, ethyl, the cyclopropyl that n-pro-pyl or isopropyl replace, cyclobutyl, cyclopenta, cyclohexyl, cyclopropyl oxygen base, cyclobutyl oxygen base, cyclopentyloxy, cyclohexyl oxygen base, the cyclopropyl sulfenyl, the cyclobutyl sulfenyl, the cyclopenta sulfenyl, the cyclohexyl sulfenyl, cyclopropyl amino, cyclobutyl amino, cyclopenta amino or cyclohexyl amino.

R ¹⁹The preferred hydrogen, optional by methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group or the sec-butyl of cyano group, hydroxyl, fluorine, chlorine, methoxyl group, ethyoxyl, positive propoxy or isopropoxy replacement, optional by acrylic, cyclobutenyl, propinyl or the butynyl of cyano group, fluorine, chlorine or bromine replacement or optional separately cyclopropyl, cyclobutyl, cyclopenta or the cyclohexyl that is replaced by cyano group, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl separately separately of representing.

R ²⁰The preferred hydrogen of representing, representative is optional separately by cyano group, hydroxyl, fluorine, chlorine, methoxyl group, ethyoxyl, the methyl that positive propoxy or isopropoxy replace, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group or sec-butyl, optional separately by cyano group, fluorine, the acrylic that chlorine or bromine replaces, cyclobutenyl, propinyl or butynyl, optional separately by cyano group, fluorine, chlorine, bromine, methyl, ethyl, the cyclopropyl that n-pro-pyl or isopropyl replace, cyclobutyl, cyclopenta or cyclohexyl, or it is optional by nitro, cyano group, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, the sec-butyl or the tert-butyl group, trifluoromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, the phenyl that difluoro-methoxy or trifluoromethoxy replace is perhaps with R ¹⁹Representative is optional separately by the fourth-1 of methyl or ethyl replacement, 4-two bases (1, the 3-propylidene), penta-1,5-two bases, 1-oxa-fourth-1,4-two bases or 3-oxa-penta-1,5-two bases together.

X ⁴Preferred nitro, cyano group, carboxyl, carbamoyl, formoxyl, sulfamoyl, hydroxyl, amino, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, trifluoromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, difluoro-methoxy or the trifluoromethoxy represented.

X ⁵Preferred nitro, cyano group, carboxyl, carbamoyl, formoxyl, sulfamoyl, hydroxyl, amino, fluorine, chlorine, bromine, methyl, ethyl, n-pro-pyl or isopropyl, normal-butyl, isobutyl group, sec-butyl or the tert-butyl group, trifluoromethyl, methoxyl group, ethyoxyl, positive propoxy or isopropoxy, difluoro-methoxy or the trifluoromethoxy represented.

During preferred extremely especially formula (IIa) examples for compounds as herbicide-safener of the present invention is listed in the table below.

Table:Formula (IIa) examples for compounds

During preferred extremely especially formula (IIb) examples for compounds as herbicide-safener of the present invention is listed in the table below.

TableFormula (II b) examples for compounds

During preferred extremely especially formula (II c) examples for compounds as herbicide-safener of the present invention is listed in the table below.

Table:Formula (II c) examples for compounds

During preferred extremely especially formula (II d) examples for compounds as herbicide-safener of the present invention is listed in the table below.

TableFormula (II d) examples for compounds

During preferred extremely especially formula (II e) examples for compounds as herbicide-safener of the present invention is listed in the table below.

TableFormula (II e) examples for compounds

Most preferably have as the compound [component (b)] that improves the crop compatibility: cloquitocet_mexyl, fenchlorazole, the acid of Shuan Ben oxazole, mefenpyrdiethyl, Xie Cao oxazole, fenclorim, cumyluron, vanilla are grand, dichlormide, dimepiperate and Compound I I e-5 and II e-11, lay special stress on cloquitocet_mexyl, mefenpyrdiethyl, the acid of Shuan Ben oxazole, Xie Cao oxazole, dichlormide, fenclorim and Compound I Ie-5.

During the example that comprises the selective herbicidal bond of the present invention of one of a kind of formula (I) reactive compound and above-mentioned safener respectively is listed in the table below.

TableThe example of bond of the present invention

Formula (I) reactive compound	Safener
		I-1	Cloquitocet_mexyl
I-1	Fenchlorazole
		I-1	The acid of Shuan Ben oxazole
I-1	Mefenpyrdiethyl
		I-1	Xie Cao oxazole
I-1	Fenclorim
		I-1	Cumyluron
I-1	Vanilla is grand
		I-1	Dichlormide
I-1	Dimepiperate
		I-1	IIe-11
I-1	IIe-5
		I-2	Cloquitocet_mexyl
I-2	Fenchlorazole
		I-2	The acid of Shuan Ben oxazole
I-2	Mefenpyrdiethyl
		I-2	Xie Cao oxazole
I-2	Fenclorim
		I-2	Cumyluron
I-2	Vanilla is grand
		I-2	Dichlormide
I-2	Dimepiperate
		I-2	IIe-11

Formula (I) reactive compound	Safener
		I-2	II?e-5
I-3	Cloquitocet_mexyl
		I-3	Fenchlorazole
I-3	The acid of Shuan Ben oxazole
		I-3	Mefenpyrdiethyl
I-3	Xie Cao oxazole
		I-3	Fenclorim
I-3	Cumyluron
		I-3	Vanilla is grand
I-3	Dichlormide
		I-3	Dimepiperate
I-3	IIe-5
		I-3	IIe-11
I-4	Cloquitocet_mexyl
		I-4	Fenchlorazole
I-4	The acid of Shuan Ben oxazole
		I-4	Mefenpyrdiethyl
I-4	Xie Cao oxazole
		I-4	Fenclorim
I-4	Cumyluron
		I-4	Vanilla is grand
I-4	Dichlormide
		I-4	Dimepiperate
I-4	II?e-11
		I-4	II?e-5
I-5	Cloquitocet_mexyl
		I-5	Fenchlorazole
I-5	The acid of Shuan Ben oxazole
		I-5	Mefenpyrdiethyl
I-5	Xie Cao oxazole

Formula (I) reactive compound	Safener
		I-5	Fenclorim
I-5	Cumyluron
		I-5	Vanilla is grand
I-5	Dichlormide
		I-5	Dimepiperate
I-5	II?e-5
		I-5	II?e-11
I-6	Cloquitocet_mexyl
		I-6	Fenchlorazole
I-6	The acid of Shuan Ben oxazole
		I-6	Mefenpyrdiethyl
I-6	Xie Cao oxazole
		I-6	Fenclorim
I-6	Cumyluron
		I-6	Vanilla is grand
I-6	Dichlormide
		I-6	Dimepiperate
I-6	II?e-5
		I-6	II?e-11

(II a) compound is a known compound, and/or can be by known method preparation itself (referring to WO-A-9I/07874, WO-A-95/07897) as the general formula of safener.

As general formula (II b) compound of safener is known compound, and/or can be by known method preparation (referring to EP-A-191736) itself.

As general formula (II c) compound of safener is known compound, and/or can be by known method preparation (referring to DE-A-2218097, DE-A-2350547) itself.

As general formula (II d) compound of safener is known compound, and/or can be by known method preparation (referring to DE-A-19621522/US-A-6235680) itself.

As general formula (II e) compound of safener is known compound, and/or can be by known method preparation (referring to WO-A-99/66795/US-A-6251827) itself.

Beat allly be, have now found that the active agent combinations of safener (antipoison) of the aryl ketones of replacement of general formula defined above (I) and above-mentioned (b) part, when having extraordinary compatibility with useful plants, also have good desinsection and/or acaricidal activity, and can in various crop, be used for selectivity control insect, described crop specifically has cereal (especially barley), and grain, corn and paddy rice.

Will be understood that among the present invention and beat allly be, from numerous known can be to the safener or antipoison of antiweed to the destructive drug effect of crop, compound of finding particularly above-mentioned (b) part almost completely cyclic dicarbonyl compounds of the replacement of cancelling (I) and does not have a negative impact to desinsection and/or acaricidal activity to the destructive drug effect of crop.

And, also will be understood that very beat all be above-mentioned (b) part compound almost completely the cyclic dicarbonyl compounds of the replacement of cancelling (I) to the destructive drug effect of crop, and in some cases even the desinsection and/or the acaricidal activity of the cyclic dicarbonyl compounds of raising formula (I), so that observe synergistic effect.

The present invention emphasizes is the preferred especially of (b) part and most preferredly has particularly advantageous drug effect in conjunction with component, in particular for not injuring the cereal plant, and for example wheat, barley and rye, and crops such as grain, corn and paddy rice.

The bond of reactive compound can be generally used for, for example, and following plant:

Dicotyledonous crops with the subordinate:Gossypium (Gossypium), Glycine (Glycine), Beta (Beta), Daucus (Daucus), Phaseolus (Phaseolus), Pisum (Pisum), Solanum (Solanum), linum (Linum), Ipomoea (Ipomoea), Vetch (Vicia), Nicotiana (Nicotiana), tomato belongs to (Lycopersicon), Arachis (Arachis), Brassicas (Brassica), Lactuca (Lactuca), Cucumis (Cucumis), Cuburbita, Helianthus (Helianthus).

Monocot crops with the subordinate:Oryza (Oryza), Zea (Zea), Triticum (Triticum), Hordeum (Hordeum), Avena (Avena), Secale (Secale), jowar belong to (Sorghum), Panicum (Panicum), saccharum (Saccharum), Ananas (Ananas), Asparagus (Asparagus), allium (Allium).

Yet the use of active agent combinations never only limits to above-mentioned genus, but extends to other plant in an identical manner.

The advantageous effects of active agent combinations finite concentration than the time remarkable especially.Yet the weight ratio of reactive compound in active agent combinations also can change in the scope of broad.Generally speaking, corresponding to formula (I) reactive compound or its salt of every weight portion, there are 0.001 to 1000 weight portion, preferred 0.01 to 100 weight portion, preferred especially 0.05 to 10 weight portion and most preferably improve one of compound (antipoison/safener) of crop compatibility among above-mentioned (b) of 0.07 to 1.5 weight portion.

Reactive compound or active agent combinations can be converted into conventional formulation, for example solution, emulsion, wetting powder, suspending agent, pulvis, powder agent, paste, soluble powder, granule, outstanding newborn concentrating agents, with the microcapsules in reactive compound impregnated natural and synthetic and the polymer.

Described preparation prepares in a known way, for example reactive compound is mixed with filler, promptly mixes with liquid flux and/or solid carrier, alternative simultaneously surfactant, i.e. emulsifier and/or dispersant and/or the blowing agent of using.

If the filler that uses is water, also can be for example with an organic solvent as cosolvent.The appropriate liquid solvent mainly contains: aromatic compound, for example dimethylbenzene, toluene or Fluhyzon; Chlorinated aromatic compound or chloro aliphatic hydrocarbon, for example chlorobenzene, vinyl chloride or carrene; Aliphatic hydrocarbon, for example cyclohexane or alkane are as mineral oil fractions, mineral oil and vegetable oil; Alcohol, for example butanols or ethylene glycol and ether thereof and ester; Ketone, for example acetone, MEK, methyl iso-butyl ketone (MIBK) or cyclohexanone; Intensive polar solvent, for example dimethyl formamide and dimethyl sulfoxide (DMSO); And water.

The solid carrier that is fit to has:

Ammonium salt for example, the natural minerals of pulverizing is kaolin, clay, talcum powder, chalk, quartz, attapulgite, montmorillonite or diatomite for example, and the synthetic material of pulverizing for example highly silica, aluminium oxide and the silicate of pulverizing; The solid carrier that is applicable to granule has: for example pulverize and the natural rock of classification for example calcite, marble, float stone, sepiolite and dolomite, and the synthetic particle of inorganic and organic powder, and organic material particle for example wood sawdust, coconut husk, corncob and tobacco stem; The emulsifier and/or the blowing agent that are fit to have: for example polyoxyethylene fatty acid ester, polyoxyethylene aliphatic alcohol ether, for example alkylaryl polyglycol ether, alkylsulfonate, alkyl sulfate, arylsulphonate and protein hydrolysate of nonionic and anion emulsifier for example; The dispersant that is fit to has: for example lignin sulfite waste liquor and methylcellulose.

Can use tackifier in the preparation; natural and the synthetic polymer of for example carboxymethyl cellulose, and powder, particle or latex shape, for example gum Arabic, polyvinyl alcohol and polyvinyl acetate; and natural phospholipid for example cephalin and lecithin, and synthetic phospholipid.Other additives can be mineral oil and vegetable oil.

Can use colouring agent, for example inorganic pigment, for example iron oxide, titanium oxide and Prussian blue, and organic dyestuff for example alizarin dyes, azo dyes and metal phthalocyanine dyestuff, and micronutrient for example molysite, manganese salt, boron salt, mantoquita, cobalt salt, molybdenum salt and zinc salt.

Preparation contains the reactive compound of 0.1 to 95 weight %, preferred 0.5 to 90 weight % usually, comprises the reactive compound with safe effect.

Active agent combinations is generally used with the form of promptly using (ready-to-use) preparation.Yet, be included in the form of the independent preparation that the reactive compound in the active agent combinations also can in use mix, promptly use with the form of canned mixture.

Active agent combinations also can itself or its preparation form, can also promptly mix use with other known weed killer herbicide with the form of preparation or canned mixture.Also can be the reactive compound known, for example the mixture of fungicide, insecticide, miticide, nematocide, attractant, disinfectant, bactericide, bird repellent, growth regulator, plant nutrient and soil conditioner with other.Some is used, particularly uses by the method after emerging, also can advantageously in preparation, comprise following other additives: mineral oil or vegetable oil (for example commercially available prod " Rako Binol ") with plant compatibility, or ammonium salt, for example ammonium sulfate or ammonium thiocyanate.

Active agent combinations can itself, its dosage form or use by the type of service of further dilution preparation, for example i.e. solution of usefulness, suspending agent, emulsion, pulvis, paste and granule by dosage form.Use and be usual manner, for example water, spray, atomize, dust or broadcast sowing.

The rate of application of active agent combinations can change within the specific limits; In various factors, rate of application depends primarily on weather and edaphic factor.Generally speaking, rate of application is 0.005 to 5kg per hectare, preferred 0.01 to 2kg per hectare, preferred especially 0.05 to 1.0kg per hectare.

Active agent combinations both can plant emerge preceding, also can after plant emerges, use, promptly by the method before emerging and the method after emerging use.

According to its characteristic, safener to be used can be used for the seed (seed dressing) of preliminary treatment crop, perhaps can put into prior to seeding and broadcast ditch (seed furrows), perhaps can use with weed killer herbicide after plant emerges preceding or emerges.

Active agent combinations is applicable to the animal pest that control agricultural, animal health, forest, storage product and material protection and health field run into, preferred arthropods and nematode, particularly insect and arachnid.They to common sensitivity and resistance species and all or some developmental stage have activity.Above-mentioned insect comprises:

Isopoda (Isopoda), for example, comb beach louse (Oniscus asellus), pillworm (Armadilliudium vulgare) and ball pillworm (Porcellio scaber).

Doubly sufficient order (Diplopoda), for example, Blaniulus guttulatus.

Lip foot order (Chilopoda), for example, Geophilus carpophagus, Scutigeraspp..

Comprehensive order (Symphyla), for example, Scutigerella immaculata.

Thysanoptera (Thysanura), for example, silverfish (Lepisma saccharina).

Collembola (Collembola), for example, arms Onychiurus arcticus (Onychiurus armatus).

Orthoptera (Orthoptera), for example, tame Xi (Acheta domesticus), Gryllotalpa spp (Gryllotalpa spp.), African migratory locust (Locusta migratoriamigratorioides), black locust belong to (Melanoplus spp.), desert locust (Schistocercagregaria).

Blattaria (Blattaria), for example, oriental cockroach (Blatta orientalis), American cockroach (Periplaneta americana), leucophaea maderae (Leucophaeamaderae), blatta germanica (Blattella germanica).

Dermaptera (Dermaptera), for example, European earwig (Forficulaauricularia).

Isoptera (Isoptera), for example, Reticulitermes (Reticulitermes spp.).

Anoplura (Phthiraptera), for example, body louse (Pediculus humanus corporis), Haematopinus (Haematopinus spp.), Linognathus (Linognathus spp.), Trichodectes (Trichodectes spp.), Damalinia (Damalinia spp.).

Thrips (Thysanoptera), for example, greenhouse bar hedge thrips (Hercinothripsfemoralis), onion thrips (Thrips tabaci), palm thrips (Thrips palmi), alfalfa thrips (Frankliniella occidentalis).

Heteroptera (Heteroptera), for example, Eurygasterspp belongs to (Eurygaster spp.), Dysdercus intermedius, square butt stinkbug (Piesma quadrata), bed bug (Cimex lectularius), phodnius prolixus (Rhodnius prolixus), Triatoma (Triatoma spp.).

Homoptera (Homoptera), for example, wild cabbage aleyrodid (Aleurodes brassicae), cassava aleyrodid (Bemisia tabaci), greenhouse whitefly (Trialeurodes vaporariorum), cotten aphid (Aphis gossypii), cabbage aphid (Brevicoryne brassicae), the tea Fischer conceals knurl aphid (Cryptomyzus ribis), aphis fabae (Aphis fabae), apple aphid (Aphispomi), wooly aphis (Eriosoma lanigerum), mealy plum aphid (Hyalopterusarundinis), grape phylloxera (Phylloxera vastatrix), the goitre woolly aphid belongs to (Pemphigus spp.), English grain aphid (Macrosiphum avenae), tumor aphid genus (Myzusspp.), phorodon aphid (Phorodon humuli), rhopalosiphum padi (Rhopalosiphumpadi), Empoasca flavescens (Empoasca spp.), Euscelis bilobatus, rice leafhopper (Nephotettix cincticeps), water wood hard a red-spotted lizard (Lecanium corni), black scale (Saissetia oleae), small brown rice planthopper (Laodelphax striatellus), brown planthopper (Nilaparvata lugens), red kidney Aspidiotus (Aonidiell aaurantii), ivy Aspidiotus (Aspidiotus hederae), mealybug belongs to (Pseudococcus spp.), Psylla spp (Psylla spp.).

Lepidoptera (Lepidoptera), for example, Pectinophora gossypiella (Pectinophoragossypiella), loose looper (Bupalus piniarius), winter geometrid moth (Cheimatobiabrumata), the thin moth of apple (Lithocolletis blancardella), apple ermine moth (Hyponomeuta padella), diamond-back moth (Plutella xylostella), malacosoma neustria (Malacosoma neustria), pornography and drug moth (Euproctis chrysorrhoea), Euproctis (Lymantria spp.), cotton lyonetid (Bucculatrix thurberiella), tangerine lyonetid (Phyllocnistis citrella), Agrotis (Agrotis spp.), root eating insect belongs to (Euxoa spp.), the dirty Noctua (Feltia spp.) of cutting, earias insulana (Earias insulana), Heliothis (Heliothis spp.), tomato moth (Mamestrabrassicae), small noctuid (Panolis flammea), Spodoptera (Spodopteraspp.), cabbage looper (Trichoplusia ni), codling moth (Carpocapsapomonella), Pieris spp (Pieris spp.), straw borer spp (Chilo spp.), corn borer (Pyrausta nubilalis), Anagasta kuehniella (Ephestia kuehniella), greater wax moth (Galleria mellonella), curtain rain moth (Tineola bisselliella), bag rain moth (Tinea pellionella), brownly knit moth (Hofmannophilapseudospretella), the yellow volume of flax moth (Cacoecia podana), Capuareticulana, spruce bunworm (Choristoneura fumiferana), grape codling moth (Clysia ambiguella) (Clysia ambiguella), tea long paper moth (Homona magnanima), the green volume of oak moth (Tortrix viridana), Cnaphalocerus spp., Oulema oryzae (Oulemaoryzae).

Coleoptera (Coleoptera), for example, furniture death watch beetle (Anobium punctatum), lesser grain borer (Rhizopertha dominica), dislike bar bean weevil (Bruchidius obtectus), acanthoscelides obtectus (Acanthoscelides obtectus), North America house longhorn beetle (Hylotrupesbajulus), willow firefly chrysomelid (Agelastica alni), colorado potato beetle (Leptinotarsadecemlineata), horseradish daikon leaf beetle (Phaedon cochleariae), chrysomelid genus (Diabrotica spp.), rape golden head flea beetle (Psylliodes chrysocephala), the big Epilachna spp of Mexico (Epilachna varivestis), Atomaria spp., saw-toothed grain beetle (Oryzaephilus surinamensis), flower resembles genus (Anthonomus spp.), grain weevil belongs to (Sitophilus spp.), black grape ear image (Otiorrhynchus sulcatus), the banana collar resembles (Cosmopolites sordidus), Chinese cabbage seed tortoise resembles (Ceuthorrhynchusassimilis), alfalfa leaf resembles (Hypera postica), khapra beetle belongs to (Dermestes spp.), the spot khapra beetle belongs to (Trogoderma spp.), Anthrenus (Anthrenus spp.), moth-eaten belong to (the Attagenus spp.) of fur, moth-eaten belong to (the Lyctus spp.) of powder, pollen beetle (Meligethes aeneus), Ptinus (Ptinus spp.), golden spider beetle (Niptushololeucus), globose spider beetle (Gibbium psylloides), Tribolium (Triboliumspp.), yellow mealworm (Tenebrio molitor), click beetle belongs to (Agriotes spp.), wide chest Agriotes spp (Conoderus spp.), the west melolonthid in May (Melolonthamelolontha), the potato melolonthid (Amphimallon solstitialis), the brown New Zealand rib wing melolonthid (Costelytra zealandica), rice root weevil (Lissorhoptrus oryzophilus).

Hymenoptera (Hymenoptera), for example, pine sawfoy belongs to (Diprion spp.), real tenthredinidae (Hoplocampa spp.), the hair ant belongs to (Lasius spp.), MonomoriumMayr (Monomoriumpharaonis), Vespa (Vespa spp.).

Diptera (Diptera), for example, Aedes (Aedes spp.), Anopheles (Anophelesspp.), Culex (Culex spp.), black-tailed fruit flies (Drosophila melanogaster), Musca (Musca spp.), Fannia (Fannia spp.), calliphora erythrocephala (Calliphoraerythrocephala), Lucilia (Lucilia spp.), Carysomyia (Chrysomyiaspp.), Cuterebra (Cuterebra spp.), Gasterophilus (Gastrophilus spp.), Hyppobosca spp., Genus Stomoxys (Stomoxys spp.), Oestrus (Oestrus spp.), Hypoderma (Hypoderma spp.), Gadfly (Tabanus spp.), Tannia spp., Bibio hortulanus, Oscinella frit (Oscinella frit), grass Hylemyia (Phorbiaspp.), lamb's-quarters spring fly (Pegomyia hyoscyami), Mediterranean Ceratitis spp (Ceratitiscapitata), the big trypetid of olive (Dacus oleae), Europe daddy-longlegs (Tipula paludosa), Hylemyia (Hylemyia spp.), liriomyza bryoniae belongs to (Liriomyza spp.).

Siphonaptera (Siphonaptera), for example, Xanthopsyllacheopis (Xenopsylla cheopis), Ceratophyllus (Ceratophyllus spp.).

Arachnids, for example, Middle East gold scorpion (Scorpio maurus), latrodectus mactans (Latrodectus mactans), Acarus siro (Acarus siro), Argas (Argasspp.), Ornithodoros (Ornithodoros spp.), Dermanyssus gallinae (Dermanyssusgallinae), tea Fischer goitre mite (Eriophyes ribis), the tangerine rust mite (Phyllocoptrutaoleivora) that rues, Boophilus (Boophilus spp.), Rh (Rhipicephalusspp.), Amblyomma (Amblyomma spp.), Hyalomma (Hyalomma spp.), hard tick belongs to (Ixodes spp.), Psoroptes (Psoroptes spp.), Chorioptes (Chorioptesspp.), itch mite belongs to (Sarcoptes spp.), tarsonemid belongs to (Tarsonemus spp.), Bryobia praetiosa (Bryobia praetiosa), Panonychus citri belongs to (Panonychus spp.), Tetranychus (Tetranychus spp.), half tarsonemid belongs to (Hemitarsonemus spp.), short whisker Acarapis (Brevipalpus spp.).

Plant nematode comprises, for example, Pratylenchidae belongs to (Pratylenchus spp.), similar similes thorne (Radopholus similis), fuller's teasel stem eelworm (Ditylenchusdipsaci), the nematode (Tylenchulus semipenetrans) of partly puncturing, Heterodera (Heterodera spp.), ball Heterodera (Globodera spp.), Meloidogyne (Meloidogyne spp.), Aphelenchoides (Aphelenchoides spp.), minute hand Turbatrix (Longidorus spp.), Xiphinema (Xiphinema spp.), burr Turbatrix (Trichodorus spp.), umbrella Aphelenchoides (Bursaphelenchus spp.).

When being used as insecticide with the commercial preparation and by the type of service that the commercial preparation prepares, the form that reactive compound also can mix with synergist exists.Synergist itself not necessarily has active compound for improving the reactive compound activity.

Reactive compound content by the type of service of commercial preparation preparation can change in wide region.The activity compound concentration of type of service can be the reactive compound of 0.0000001 to 95 weight %, preferred 0.0001 to 1 weight %.

The usual manner of using to be suitable for type of service carries out.

Plant all reaches plant parts and all can handle according to the present invention.The implication of plant is interpreted as all plants and plant population among the present invention, for example need with unwanted wild plant or crop (comprising the crop that nature exists).Crop can be by conventional plant breeding and optimum seeking method or the plant that obtains by biotechnology and gene engineering method or the combination by described method, comprises genetically modified plants, also comprises the plant cultivars that is subjected to the protection of plant seedling power or is not subjected to its protection.The implication of plant parts is interpreted as all grounds of plant and underground position and organ, and for example bud, leaf, Hua Hegen, the example that can propose have leaf, needle, stem, do, flower, fruit body (fruit-body), fruit, seed, root, stem tuber and rhizome.Plant parts also comprises harvested material, and asexual and sexual propagation thing, for example seedling, stem tuber, rhizome, cutting and seed.

The processing that use reactive compound of the present invention carries out plant and plant parts, directly carry out or make compound effects by conventional treatment method in surrounding environment, habitat or storage space, described conventional treatment method for example soaks, sprays, evaporates, atomizes, broadcasts sowing, smears (brushing-on), for breeding particularly seed of thing, also can be coated with one or more layers.

As mentioned above, can handle all plants and its position according to the present invention.In preferred embodiments, wild plant kind and botanical variety or have been handled by the biological breeding method of routine, the kind that for example merge to obtain by hybridization or protoplast and the position of described plant variety.In more preferred, if handled genetically modified plants and botanical variety (biology of genetic modification (geneticallymodified organism)) and the position thereof that obtains by suitable also can the combining of gene engineering with conventional method.Term " position " or " position of plant " or " plant parts " are explained as above.

Especially preferably the plant of handling according to the present invention is a botanical variety commercially available separately or that use.

According to plant species or botanical variety, its plantation place and growth conditions (soil, weather, vegetation period, nutrition), processing of the present invention also can produce superadditivity (superadditive) (" collaborative ") effect.Can obtain the following effect that surpasses actual desired thus, for example can reduce rate of application and/or widen activity profile and/or improve the material that can use by the present invention and the activity of composition, improve vegetation growth state, improve high temperature or cold tolerance, raising to arid or to the tolerance of water or soil salt content, improve the quality of blooming, make gather simpler and easy, hasting of maturity, raising output, improve the quality of the product of gathering and/or improve its nutritive value, improve bin stability and/or its processing characteristics of the product of gathering.

Preferably be included in all plants of accepting genetic material in the genetic modification according to the present invention pending genetically modified plants or botanical variety (promptly obtaining by gene engineering), described genetic material is given described plant with particularly advantageous useful properties.The example of described characteristic have improve vegetation growth state, improve high temperature or cold tolerance, raising to arid or to the tolerance of water or soil salt content, improve the quality of blooming, make gather simpler and easy, hasting of maturity, raising output, improve the quality of the product of gathering and/or improve its nutritive value, improve bin stability and/or its processing characteristics of the product of gathering.Need other examples of ben described characteristic to have and improve the resistance of plant animal and microorganism insect, for example to the resistance of insect, acarid, phytopathogenic fungi, bacterium and/or virus, and improve the tolerance of plant to some weeding active compound.The example of the genetically modified plants that can propose is important crop, such as grain (wheat, rice), corn, soybean, potato, cotton, rape (oilseed rape) and fruit plant (fruit is apple, pears, citrus fruits and grape), ben is corn, soybean, potato, cotton and rape.Ben characteristic is by form toxin in plant corpus, particularly the toxin that is formed in plant corpus by the genetic material of bacillus thuringiensis,Bt (for example by gene C ry IA (a), Cry IA (b), Cry IA (c), Cry IIA, Cry III A, Cry III B2, Cry9c, Cry2Ab, Cry3Bb and Cry IF and in conjunction with) improves the resistance (be designated hereinafter simply as " Bt plant ") of plant to insect.Ben other characteristics are for improving the tolerance of plant to some weeding active compound, for example imidazolone type, sulfonylurea, glyphosate (glyphosate) or phosphinotricin (for example " PAT " gene).The gene of being discussed of giving desirable characteristics also can mutually combine in the genetically modified plants body.The example of " the Bt plant " that can propose is that commercially available brand name is YIELD (for example corn, cotton, soybean),

(for example corn),

(for example corn),

(cotton),

(cotton) and

The corn mutation of (potato), cotton mutation, soybean mutation and potato mutation.The example of the plant with herbicide tolerant that can propose is that commercially available brand name is Roundup (having the glyphosate tolerance, for example corn, cotton, soybean), Liberty

(having the phosphinotricin tolerance, for example rape), (having imidazolinone-tolerant) and

The corn mutation of (having the sulfonylureas tolerance, for example corn), cotton mutation and soybean mutation.The plant with Herbicid resistant that can propose (with the plant of the herbicide tolerant mode breeding of routine) also comprises by name Commercially available mutation (for example corn).Certainly, more than narration also is applicable to the botanical variety with described or genetic characteristics leaved for development, and described botanical variety will be developed and/or goes on the market in future.

Above-mentioned plant can particularly advantageously be handled with the mixture of reactive compound according to the present invention.The preferable range of said mixture also is applicable to the processing of described plant.Ben for plant being handled with the special mixture that proposes of the present invention.

Application Example

Preparation 20WS preparation is also dressed seed subsequently

In agate mortar, safener and the reactive compound for preparing 20WS preparation aequum is dissolved in the acetone, and adds an amount of preparation that does not contain reactive compound (being actually used in preparation Gaucho70WS).Mixture only is dried to detects a spot of residual moisture.Use scraper that material is separated from the mortar wall carefully, and material is crushed to drying in mortar.It is big to the beaker of following degree to be filled to size with the experimental preparation that as above makes of the amount fit amount of seed to be dressed seed, and the size of described beaker is big in the seed dressing process, seed filling its at the most 1/3rd.The water (characteristic that depends on the surface of the seed) that adds capacity again.Then seed is packed in the beaker that fills preparation and water and on the test tube shaking machine, dress seed by scraper or glass rod.After treating that preparation is evenly distributed on the seed as far as possible, that seed is dry in fume hood.

In seed tray (seed tray), test

(20 * 20 * 5cm) fill with sand loam vinyl disc with 31.Use stamping machine that the accumulation degree of depth that crop needs is studied in soil compaction to reaching.In each kind dish,, use above-mentioned stamping machine to bury to soil by tweezers 20 seeds of spacing sowing with rule.Test container is placed the greenhouse, and use stamping machine surface slowly compacting once more.Except substances, also to undressed to test in the same old way.Each deformation program adopts at least 2 kind dishes.Kind of a dish watered and cover with film emerge until plant.After emerging, the kind dish waters twice every day.By adding up the plant number that has germinateed and after after planting 5～14 days, assessing compare definite damage situations (representing) in the same old way with % with untreated.

The greenhouse test result of seed dressing back safener:

Example I-1-1

Be known in WO 03/029213, embodiment numbers I-1-c-11

Table A

Table B

Table C

Method: the safener test after the spraying

Deformation program a)

Solvent: the DMF of 7 weight portions

Emulsifier: the alkylaryl polyglycol ether of 2 weight portions

For preparing suitable active agent preparations,, and dope is diluted to desired concn with running water with the reactive compound of 1 weight portion and the solvent and the emulsifier of described amount.The safener (is WP20 for mefenpyrdiethyl) of aequum is sneaked in the thinned water.In addition, also add the 2g active component/liter rape oil methyl esters 500EW.By spray boom with the reactive compound of desired concn and safener handle by rhopalosiphum padi (Rhopalosiphum padi) infect 2 winter leaf phase barley leaf, the rate of application of water is 300l/ha.For each deformation program, test at least twice.Assess by the percentage damage situations of after 7 days and/or 14 days, determining plant, wherein by with untreated to relatively all assess in the same old way to handling plant and the percentage damage situations of newborn plant and the percentage lethality of cereal aphid.100% impaired expression plant death, and 0% expression not damaged.The cereal aphid is had 100% drug effect represent to kill all aphids; The no aphid of 0% expression is killed.

Deformation program b)

At deformation program b) in, with reactive compound with deformation program a) identical desired concn and mefenpyrdiethyl WP20 and 2g active component/liter rape oil methyl esters 500EW mix with the form of SC preparation and use.Implement and assessment is carried out as described in a) as deformation program.

Spraying back safener is to the greenhouse test result of barley rhopalosiphum padi in winter

Example I-1-2

Be known in WO 03/029213, embodiment numbers I-1-a-9

Table D(deformation program b)

Table E(deformation program b)

Table F(deformation program b)

Table G(deformation program a)

Table H(deformation program a)

Calculate the formula of the lethality of two kinds of active agent combinations

The expection activity of two kinds of given active agent combinations can be according to S.R.Colby, Weeds 15(1967), the 20-22 page or leaf calculates, and is as follows:

If

X is with rate of application mG/ha or with concentration mLethality when ppm uses reactive compound A,

Y is with rate of application nG/ha or with concentration nLethality when ppm uses reactive compound B,

E is with rate of application mG/ha and nG/ha or with concentration mPpm and nLethality when ppm uses reactive compound A and B,

Then

$E=X+Y-\frac{X\·Y}{100}.$

Among the present invention, lethality is determined as percentage.0% expression and lethality to equate in the same old way, and 100% lethality is represented not observe and is infected.

If actual lethality is higher than calculated value, then the activity of bond has superadditivity, promptly has synergistic effect.In this case, actual observation to lethality must surpass adopt following formula calculate expected mortality (E).

Spray application embodiment

Solvent: water

Auxiliary agent: the rape oil methyl esters (0.1% active component/liter)

For preparing the suitable solution of using, the preparation of 1 weight portion is mixed with an amount of water and auxiliary agent, and dope is diluted with water to desired concn.

Example I

The cotten aphid test

The cotton (Gossypiumherbaceum) that to seriously be infected by cotten aphid (Aphis gossypii) is used solution spray to the point that runs off (runoff point) with desired concn.

Embodiment J

The black peach aphid test

The green pepper (Capsicumsativum) that will seriously be infected by black peach aphid (Myzus persicae) is used solution spray to running off a little with desired concn.

Embodiment K

Wheat does not have the test of net aphid

To do not had barley (Hordeum vulgare) that net aphid (Metopolophium dirhodum) seriously infects by wheat and use solution spray to running off a little with desired concn.

Through behind the required time, measure the percentage lethality.All aphids are killed in 100% expression; The no aphid of 0% expression is killed.With the lethality substitution Colby formula that records.

In this test, for example, the application's following active agent combinations is compared with the reactive compound of using separately and is shown the collaborative activity that strengthens:

Table I

The insect of harm plant

The cotten aphid test

^*Measured value=actual the activity that records

^*The activity that calculated value=use Colby formula calculates

Table I (continuing)

The insect of harm plant

The cotten aphid test

^*Measured value=actual the activity that records

^*The activity that calculated value=use Colby formula calculates

Table J

The insect of harm plant

The black peach aphid test

^*Measured value=actual the activity that records, ^*The activity that calculated value=use Colby formula calculates

Table K

The insect of harm plant

Wheat does not have the test of net aphid

^*Measured value=actual the activity that records

^** the activity that calculated value=use Colby formula calculates

Embodiment L

Critical concentration test/soil insect-genetically modified plants are handled

Test insect: larva in chrysomelid (Diabrotica the balteata)-soil of cucumber strip

Solvent: the acetone of 7 weight portions

Emulsifier: the alkylaryl polyglycol ether of 1 weight portion

For preparing suitable active agent preparations, mix the reactive compound of 1 weight portion and the solvent of described amount, add the emulsifier of described amount, and dope is diluted with water to desired concn.

Active agent preparations is poured onto on the soil.Herein, the activity compound concentration in the preparation is in fact unimportant, the crucial weight (being expressed as ppm (mg/l)) that only is reactive compound in the per unit volume soil.Soil is inserted in 0.251 basin, left standstill in the time of 20 ℃.

After described preparation process finished, cultivated species YIELDGUARD (the U.S. Monsanto house mark) corn (maize corn) that 5 strains vernalization are handled was inserted in each basin at once.After 2 days, the test insect of correspondence is inserted in the soil of having handled.After 7 days, determine reactive compound drug effect (1 strain plant=20% activity) by the corn plant strain number that statistics has been germinateed.

Embodiment M

Cigarette bud-leaf moth (Heliothis virescens) test-genetically modified plants are handled

Solvent: the acetone of 7 weight portions

Emulsifier: the alkylaryl polyglycol ether of 1 weight portion

For preparing suitable active agent preparations, mix reactive compound and the solvent of described amount and the emulsifier of described amount of 1 weight portion, and dope is diluted with water to desired concn.

In the active agent preparations with cultivated species Roundup Ready (U.S. Monsanto house mark) soybean (Glycinemax) seedling immersion desired concn it is handled, when leaf is still moistening, insert cigarette bud-leaf moth.

Through behind the required time, determine the death of insect.

Claims (7)

1. the composition that contains the following active agent combinations of effective dose is used to prevent and treat the purposes of insect, and described active agent combinations contains

(a) at least a formula (I) compound

Wherein,

W represents C ₁-C ₆Alkyl,

X represents C ₁-C ₆Alkyl,

Y represents halogen,

Z represents hydrogen,

CDC represents following group

Wherein,

A and B with the carbon atom that they were connected represent saturated, do not replace or by C ₁-C ₈Annular atoms that alkoxyl replaces, optional is by the C of oxygen or sulfur ₃-C ₁₀Cycloalkyl,

D represents hydrogen,

G represents halogen;

With

(b) at least a compound that improves the crop compatibility that is selected from following compound:

Cloquitocet_mexyl,

One of and/or following compound by general formula definition,

General formula (IIb)

Wherein

A ²Representative has alkane two bases of 1 or 2 carbon atom,

R ⁹Representation hydroxy or C ₁-C ₆Alkoxyl,

X ²Represent hydrogen or halogen,

X ³Represent hydrogen.

2. claim 1 is used the purposes of composition for preventing and controlling insect, and described composition comprises following formula (I) compound,

Wherein,

A, B represent a wherein optional annular atoms by oxygen or sulfur and optional by C with the carbon atom that they connected ₁-C ₈The alkoxyl list replaces or dibasic saturated C ₃-C ₁₀Cycloalkyl,

G represents chlorine or bromine.

3. claim 1 is used the purposes of composition for preventing and controlling insect, and described composition comprises following formula (I) compound,

Wherein,

W represents C ₁-C ₃Alkyl,

X represents C ₁-C ₄Alkyl,

Y represents chlorine or bromine,

A, B represent a wherein optional annular atoms by oxygen or sulfur and optional by C with the carbon atom that they connected ₁-C ₄The mono-substituted saturated C of alkoxyl ₃-C ₇Cycloalkyl,

G represents chlorine.

4. claim 1 is used the purposes of composition for preventing and controlling insect, and described composition comprises following formula (I) compound,

Wherein,

W represent methylidene or ethyl,

X represent methylidene, ethyl or propyl group,

Y represents chlorine or bromine,

On behalf of a wherein optional annular atoms, A, B replaced by oxo with the carbon atom that they connected and is optional by the mono-substituted saturated C of methoxyl group, ethyoxyl, propoxyl group, butoxy or isobutoxy ₅-C ₆Cycloalkyl,

G represents chlorine.

5. claim 1 is used the purposes of composition for preventing and controlling insect, and described composition comprises following formula (I) compound,

Wherein,

W represent methylidene or ethyl,

X represent methylidene, ethyl or propyl group,

Y represents chlorine or bromine,

On behalf of a wherein optional annular atoms, A, B replaced by oxo with the carbon atom that they connected and is optional by the mono-substituted saturated C of methoxyl group, ethyoxyl, propoxyl group, butoxy or isobutoxy ₅-C ₆Cycloalkyl,

G represents chlorine.

6. the method for control insect and/or arachnid is characterized in that making the composition of claim 1 definition to act on insect and/or arachnid and/or their habitat.

7. claim 1 is used the purposes of composition for preventing and controlling insect and/or arachnid, and wherein the compound of improvement effect compatibility is a cloquitocet_mexyl.