CN100493441C - Method for detecting the skin irritation intensity caused by skin care products and arrangement thereof - Google Patents

Method for detecting the skin irritation intensity caused by skin care products and arrangement thereof Download PDF

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CN100493441C
CN100493441C CNB2006101036078A CN200610103607A CN100493441C CN 100493441 C CN100493441 C CN 100493441C CN B2006101036078 A CNB2006101036078 A CN B2006101036078A CN 200610103607 A CN200610103607 A CN 200610103607A CN 100493441 C CN100493441 C CN 100493441C
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skin
microprocessor
skin care
care item
probe
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CN101112304A (en
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许越
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Abstract

The invention relates to a method and a device which adopts multiple parameter to detect the stimulus strength of the skin care product to the skin. A plurality of physical or chemical parameters are collected after the skin being stimulated by the skin care product, including the temperature, the electric conductivity, the pH value of the stimulus position of the skin and the information of the active change of O2, NO, CO2 and the differential centrifugation ion, the effective outcome of the parameter is achieved through the comprehensive analysis and calculation of the solidified software procedure which is arranged inside a computer microprocessing unit, and the degree of the stimulus strength is displayed by the alternative audio control, the lamp control and the liquid crystal display device. The invention has the advantages of acute, rapid, exact and easy operation and so on, which supplies the remote service for the individual through network and achieves the purpose that the individual uses the skin care product optimally.

Description

A kind of method and apparatus that detects skin care item to skin irritation intensity
Affiliated technical field
The present invention relates to a kind of method and apparatus that detects skin care item to skin irritation intensity, particularly a kind of multiparameter that adopts detects the method and apparatus of skin care item to skin irritation intensity.
Background technology
Along with people to the use of skin care item more and more widely and frequent, skin care item have become the necessary of skin protection beauty in people's daily life.People have often ignored skin care item because of selecting and the skin that improper use brought and the infringement of adnexa thereof when experiencing the benefit that skin care item bring.Be usually expressed as skin erythema, pimple, desquamation, pigmentation, pruritus or twinge etc., in addition also vesicle can appear, more serious disease such as erosion, alopecia.
In view of the harm that skin care item bring skin, estimate skin care item skin irritation intensity is seemed particularly important.Skin care item mainly contain two kinds of methods for skin irritant detecting pattern, are respectively to detect in vitro detection and the body.For vitro detection, it is for referencial use in full that this paper quotes the US-A-6020148 description, and this application discloses the method for a kind of vitro detection external use skin care to the stimulation of skin and eye.This method is to set up cell culture model after smearing the chafe cell by skin care item, and further the survival rate of quantitative analysis cell is measured.The reaction of vitro detection analyzing skin to stimulating, promptly analyze the stimulation of skin care item to the human skin cell by setting up external model, can not reflect the exteroceptive real information of Skin Cell, because it is in vitro tissue or cell and be obvious, and also higher to the personnel specialty requirement from implementing angle in the difference of the external condition of soma or cell.
The check and analysis skin care item are to the existing relevant report of skin irritation in the body.4 hours patch experimental techniques are used to estimate small size and smear formed erythema behind this product (Robinson etc. are at Contact Dermatitis, " being used for the application of 4 hours human body skin speckle experimental techniques that comparison and research property evaluating skin stimulate " in 1998).Another kind method is to analyze (Rheins " method of detection epidermis biotic factor " by detecting cytokine behind scraping or the sticking bark fetching skin tissue cell, WO00/10579), but may limit the accuracy of evaluation result because stronger outside is invaded, thereby make its application be subjected to certain limitation.In recent years, occurred adopting the non-invasive method collecting cell factor or other protein to estimate the skin irritant method of human body (Perkins etc., 1998, " estimating the skin irritant noninvasive method of human body ") as the inflammatory label.But the potential problem of this method is the interaction of skin care item and inflammatory label to be tended to bring difficulty to result's explanation.
After the complicated ingredient chafes such as the spice in the skin care item, antiseptic, emulsifying agent, pigment, lucifuge agent, hair dye and some heavy metals, some physics and chemistry can take place and change in skin keratin cell and fibroblast, temperature, electrical conductivity, pH value, O can occur as the skin at local irriate position 2, CO 2, physical and chemical parameter such as NO, ion activity change.Prior art has some to be used to measure instrument and the method for skin temperature, PH.Chinese patent literature (the patent No.: 97240351.5; Publication number: CN2312450; The open date: 1999.03.31) disclose a kind of thermoesthesia analyzer, skin temperature sensation sensitivity can be accurately measured in the contrast of variations in temperature and room temperature contact temperature by the alternating temperature contact.Chinese patent literature (the patent No.: 99208559.4; Publication number: CN2364463; The open date: 2000.02.16) disclose a kind of skin soda acid attribute test instrument, it be by pick off with the measurement electrode that records and reference electrode signal respectively after data amplification, conversion, single-chip microcomputer are handled, tabling look-up behind digital filtering draws accordingly result and shows.But technique scheme is just come assay from single parameter, and evaluation means is limited, on the whole the post-stimulatory result of overall merit skin feel skin care item.In addition, the method that has some to measure oxygen, carbon dioxide in the prior art, but be not used for the skin irritation evaluation.The mensuration of electrical conductivity is seen in industrial application at present, does not see that being used for human body skin stimulates evaluation.Therefore, develop a kind of multiparameter and detect the method and apparatus of skin care item, the defective that can not only overcome the deficiency of above-mentioned evaluation methodology and estimate, and easy, the easy row of using method, true and reliable skin irritation intensity.
Summary of the invention
The technical problem to be solved in the present invention is to avoid the deficiencies in the prior art part and propose a kind of method and apparatus that skin care item detect the multiparameter of skin irritation intensity that is used for, thereby consumption guidance person uses the individuation of skin care item.
Temperature detection signal, electrical conductivity detection signal, pH value detection signal, oxygen detection signal, NO detection signal, the CO of the present invention by skin care item being smeared skin part 2Detection signal and specific ion signals collecting are in the multi-parameter monitoring module, each signal is amplified and digitized processing after signal data is transferred to microprocessor by data/address bus, utilize microprocessor solidification software program that signal data is carried out analyzing and processing, show the stimulation degree of this kind skin care item at last human body skin.The present invention solves the problems of the technologies described above the method that is adopted and comprises the steps:
Whether each the parts work of checkout gear of A. at first starting shooting is normal, consumption evenly spreads upon skin care item on the skin routinely then, and skin is popped one's head in the unitary skin temperature probe of multi-parameter monitoring, conductivity probe, pH value probe, oxygen probe, NO behind irriate successively, CO 2Probe, specific ion electrode probe touch the skin part of smearing skin care item and detect, its detection signal separately imports in the multi-parameter monitoring module, the detection signal that the multi-parameter monitoring module will be imported into carries out digitized processing, by data/address bus the multiparameter data is exported then;
B. the multiparameter data are input in the microprocessor in the intelligent control unit, and the calculation process of multiparameter data solidification software program in microprocessor analyzes the stimulus intensity parameter of experimenter's skin to this skin care item, and data accumulating is preserved;
C. data processed is shown that by multi-functional display module skin care item are to skin irritant intensity;
D. the user can arrive network with transfer of data by communication module, for the user provides remote service.
Data parameters in the microprocessor of the described intelligent control unit of step B is transferred in the memory module, can remember under the different condition skin care item to the stimulus parameter of skin, for the follow-up service of individuality provides data information.
The described multi-functional display module of step C can provide the mode of three kinds of different demonstration skin irritation intensity, selects for the user.First kind can show red, yellow, green three kinds of results by the lamp control, and red light is represented strong stimulation, and yellow expression is weak to stimulate, and green light is represented non-stimulated; Second kind can show different stimulus intensities by acoustic control; The third can pass through liquid crystal display skin irritation intensity.
Invention is further implemented:
Manufacture and design a kind of multiparameter and detect the device of skin care item, comprise power subsystem, multi-parameter monitoring unit, intelligent control unit and display unit skin irritation intensity.
Described multi-parameter monitoring unit comprises probe group and parameter monitoring module, and the probe group comprises skin temperature probe, conductivity probe, pH value probe, oxygen probe, NO probe, CO 2Probe and specific ion electrode probe.Detection signal outfan of described each probe inserts multi-parameter monitoring module, and the multi-parameter monitoring module is carried out digitized processing with the detection signal of input, then by data/address bus with the multiparameter transfer of data in microprocessor.
Described intelligent control unit comprises microprocessor, memory module and communication module.Microprocessor is connected with the multi-parameter monitoring module, and the multiparameter that is used to gather is handled; Memory module is connected with microprocessor, is used for arrangement and preserves data; Communication module is connected with microprocessor, data can be transmitted by network, for the user provides the individuation remote service.
Described display unit comprises multi-functional display module and display device.Multi-functional display module is connected with microprocessor, shows the skin irritation intensity results.Display device comprises light controller, sound-controlled apparatus and liquid crystal indicator, for the user provides three kinds of different display modes.
Described power subsystem comprises 5v regulated power supply or rechargeable battery pack power supply.
Compared with prior art, the present invention comprises temperature, electrical conductivity, pH value, oxygen, NO, the CO of skin stimulation location by gathering the information of a plurality of physical and chemical parameters that occur after skin is stimulated by skin care item 2With the change information of specific ion, the analysis-by-synthesis computing of solidification software program obtains the result in the process microprocessor, shows the strong and weak degree of skin irritation by alternative acoustic control, lamp control and liquid crystal indicator.The present invention has sensitivity, advantage such as quick, accurate, easy and simple to handle, and can be and individually provide remote service by network, has realized that individuation uses the purpose of skin care item.
Description of drawings
Fig. 1 is that multiparameter of the present invention detects the method flow diagram of skin care item to skin irritation intensity;
Fig. 2 is that multiparameter of the present invention detects the device circuit schematic diagram of skin care item to skin irritation intensity.
The specific embodiment
Below in conjunction with accompanying drawing, adopt most preferred embodiment that the present invention is further described in detail.With reference to Fig. 1, Fig. 2, implement multiparameter and detect the method for skin care item skin irritation intensity, comprise the steps:
Whether each the parts work of checkout gear of A. at first starting shooting is normal, consumption evenly spreads upon skin care item on the skin routinely then, skin behind irriate successively with the skin temperature of multi-parameter monitoring unit 3 probe 31, conductivity probe 32, pH value probe 33, oxygen probe 34, NO probe 35, CO 2Probe 36 and specific ion electrode probe 37 touch the skin part of smearing skin care item and detect, its detection signal separately imports in the multi-parameter monitoring module 38, the detection signal that multi-parameter monitoring module 38 will be imported into carries out digitized processing, by data/address bus the multiparameter data is exported then;
B. the multiparameter data are input among the microprocessor U1 of intelligent control unit 2, the calculation process of multiparameter data solidification software program in microprocessor U1, analyze the stimulus intensity parameter of experimenter's skin, and data accumulating is saved in the memory module 21 this skin care item;
C. the skin irritation intensive parameter that will handle can provide three kinds of modes to show skin irritation intensity by the multi-functional display module 44 of 4 li of display units, selects for the user.First kind can show that 42 show red, yellow, green three kinds of results by the lamp control, and red light is represented strong stimulation, and yellow expression is weak to stimulate, and green light is represented non-stimulated; Second kind can show that 41 show different skin irritation intensity by acoustic control; The third can show the skin irritation intensity results by liquid crystal display 43.
D. the user can arrive network with transfer of data by communication module 22, for the user provides the individuation remote service.
Data parameters among the microprocessor U1 of the described intelligent control unit 2 of step B is transferred in the memory module 21, can remember under the different condition skin care item to the stimulus parameter of skin, for the follow-up service of individuality provides data information.
Can also the present invention further be implemented:
Manufacture and design a kind of multiparameter and detect the device of skin care item, comprise power subsystem 1, intelligent control unit 2, multi-parameter monitoring unit 3 and display unit 4 skin irritation intensity.
Described multi-parameter monitoring unit 3 comprises probe group and multi-parameter monitoring module 38.The skin part that each probe places examination person to smear skin care item in use detects, and its detection signal separately inserts in the multi-parameter monitoring module 38.Multi-parameter monitoring module 38 outputs to the multiparameter data among the microprocessor U1 of intelligent control unit 2 by data/address bus.
As shown in Figure 2: the probe group in the described multi-parameter monitoring unit 3 comprises skin temperature probe 31, conductivity probe 32, pH value probe 33, oxygen probe 34, NO probe 35, CO2 probe 36 and specific ion electrode probe 37, the signal output of described each probe inserts multi-parameter monitoring module 38, multi-parameter monitoring module 38 with the input detection signal carry out digitized processing, then by data/address bus with the multiparameter transfer of data in microprocessor U1.
Described intelligent control unit 2 comprises microprocessor U1, memory module 21 and communication module 22.Microprocessor U1 detects button with S0 and is connected, and detects beginning behind the operation push-button; Microprocessor U1 is connected with multi-parameter monitoring module 38, and the multiparameter that is used to gather is handled; Memory module 21 is connected with microprocessor U1 and is used for arrangement and preserves data, according to the stimulus parameter that detects, for the follow-up service of individuality provides data information; Communication module 22 is connected with microprocessor U1, data is transmitted by network, for the user provides the individuation remote service.
Described display unit comprises multi-functional display module 44 and display device.Described multi-functional display module 44 is connected with microprocessor U1, shows the skin irritation intensity results.Display device comprises light controller 42, sound-controlled apparatus 41 and liquid crystal indicator 43, for the user provides three kinds of different display modes.
Described power subsystem comprises 5v regulated power supply U2 or rechargeable battery pack power supply.
Experiment showed, that the present invention when the skin irritation intensity of skin care item user is carried out signals collecting, monitoring, can in time show the stimulus intensity of user to certain skin care item, realized the purpose of individuation use skin care item.

Claims (7)

1. a method that detects skin care item to skin irritation intensity is characterized in that: comprise step
A. at first start checks whether the detection skin care item are normal to each parts work of device of skin irritation intensity, consumption evenly spreads upon skin care item on the skin routinely then, the skin successively skin temperature of multi-parameter monitoring unit (3) probe (31), conductivity probe (32), pH value probe (33), oxygen probe (34), NO are popped one's head in behind irriate (35), CO 2Probe (36) and specific ion electrode probe (37) touch the skin part of smearing skin care item and detect, its detection signal separately imports in the multi-parameter monitoring module (38), the detection signal that the multi-parameter monitoring module will be imported into carries out digitized processing, then by the multiparameter data output of data/address bus after with multi-parameter monitoring module digitized processing;
B. the multiparameter data after the multi-parameter monitoring module digitized processing are input in the microprocessor (U1) in the intelligent control unit (2), the calculation process of multiparameter data solidification software program in microprocessor (U1), analyze the stimulus intensity parameter of experimenter's skin, and will preserve through the data accumulating after microprocessor (U1) calculation process to this skin care item;
C. data processed is shown that by multi-functional display module skin care item are to skin irritant intensity;
D. the user will be through the transfer of data after microprocessor (U1) calculation process to network, for the user provides the individuation remote service by communication module.
2. detection skin care item according to claim 1 are to the method for skin irritation intensity, it is characterized in that: in the microprocessor (U1) of described intelligent control unit (2) after microprocessor (U1) calculation process data parameters be transferred to memory module (21), skin care item are to the stimulus parameter of skin under the memory different condition, for the follow-up service of individuality provides data information.
3. detection skin care item according to claim 1 are to the method for skin irritation intensity, it is characterized in that: described multi-functional display module (44) shows that by alternative acoustic control (41), lamp control show that (42) and liquid crystal display (43) device show the strong and weak degree of skin irritation, and the user can select different display modes.
4. a device that detects skin care item to skin irritation intensity comprises power subsystem (1), it is characterized in that: also comprise intelligent control unit (2), multi-parameter monitoring unit (3), display unit (4); Described multi-parameter monitoring unit (3) comprises probe group and multi-parameter monitoring module (38); The position that described probe group places examination person to smear skin care item is in use detected, and its detection signal separately inserts in the multi-parameter monitoring module (38); Described multi-parameter monitoring module (38) outputs to microprocessor (U1) in the intelligent control unit (2) by data/address bus with the multiparameter data; Described intelligent control unit (2) comprises microprocessor (U1), memory module (21) and communication module (22), and microprocessor (U1) is connected with detection button (S0), memory module (21) and communication module (22) respectively; Comprise multi-functional display module (44) and sound-controlled apparatus (41), light controller (42) and liquid crystal indicator (43) in the described display unit (4), multi-functional display module (44) is connected with microprocessor (U1), and sound-controlled apparatus (41), light controller (42) and liquid crystal indicator (43) are connected with multi-functional display module (44).
5. detection skin care item according to claim 4 is characterized in that the device of skin irritation intensity: described multi-parameter monitoring unit (3) comprises skin temperature probe (31), conductivity probe (32), pH value probe (33), oxygen probe (34), NO pop one's head in (35), CO 2Probe (36) and specific ion electrode probe (37); The signal output of described each probe inserts multi-parameter monitoring module (38), multi-parameter monitoring module (38) is carried out digitized processing with the detection signal of input, then by data/address bus with the microprocessor (U1) of multiparameter transfer of data in the intelligent control unit (2).
6. detection skin care item according to claim 4 is characterized in that the device of skin irritation intensity: described intelligent control unit (2) comprises microprocessor (U1), memory module (21) and communication module (22); Described microprocessor (U1) is connected with detection button (S0), detects beginning behind the operation push-button; Described microprocessor (U1) is connected with multi-parameter monitoring module (38), is used to handle the multiparameter data that multi-parameter monitoring module (38) is gathered; Described memory module (21) is connected with microprocessor (U1), is used for arrangement and preserves data; Described communication module (22) is connected with microprocessor U1, data is transmitted by network, for the user provides the individuation remote service.
7. detection skin care item according to claim 4 are to the device of skin irritation intensity, it is characterized in that: comprise multi-functional display module (44) and sound-controlled apparatus (41), light controller (42) and liquid crystal indicator (43) in the described display unit (4), the user can select different display modes to show that skin care item are to the strong and weak degree of skin irritation.
CNB2006101036078A 2006-07-24 2006-07-24 Method for detecting the skin irritation intensity caused by skin care products and arrangement thereof Expired - Fee Related CN100493441C (en)

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Publication number Priority date Publication date Assignee Title
KR200474471Y1 (en) * 2013-03-05 2014-09-18 (주)아모레퍼시픽 A Skin Diagnosis Unit based Vibration
EP2972155B1 (en) * 2013-03-15 2023-08-23 Shiseido Company, Limited Systems and methods for specifying and formulating customized topical agents
WO2020014695A1 (en) 2018-07-13 2020-01-16 Shiseido Americas Corporation System and method for adjusting custom topical agents
CN110018161B (en) * 2019-02-28 2022-05-20 北京三立慧评化妆品科技有限公司 Method for detecting irritation of cosmetic raw material and method for detecting irritation resistance of irritation-resistant product
JP7539917B2 (en) 2019-04-09 2024-08-26 株式会社 資生堂 Systems and methods for creating topical formulations with improved image capture - Patents.com

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Assignee: Xuyue (Beijing) Technology Co.,Ltd.

Assignor: Xu Yue

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Denomination of invention: Method for detecting the skin irritation intensity caused by skin care products and arrangement thereof

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