CN100464734C - Desensitizing anticarious gel and its prepn - Google Patents
Desensitizing anticarious gel and its prepn Download PDFInfo
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- CN100464734C CN100464734C CNB2006101546899A CN200610154689A CN100464734C CN 100464734 C CN100464734 C CN 100464734C CN B2006101546899 A CNB2006101546899 A CN B2006101546899A CN 200610154689 A CN200610154689 A CN 200610154689A CN 100464734 C CN100464734 C CN 100464734C
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- gel
- anticarious
- desensitizing
- water
- paraformaldehyde
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Abstract
The present invention relates to one kind of desensitizing anticarious gel and its preparation process. The desensitizing anticarious gel consists of sodium fluoride 1-5 weight portions, paraformaldehyde 5-10 weight portions, glue 3-10 weight portions and water 1000 weight portions. Its preparation process includes the following steps: 1. dissolving sodium fluoride and paraformaldehyde in water; 2. adding human acceptable acid to regulate pH value to 6-8; and 3. adding water and glue and letting stand for 1-5 days to deair and obtain the desensitizing anticarious gel. The present invention can desensitize teeth, strengthen the resistance of teeth and prevent carious.
Description
(1) technical field
The present invention relates to a kind of desensitizing anticarious gel and preparation method thereof.
(2) background technology
Injury of teeth, the dentin that dentin hypersensitiveness is meant is damaged owing to odontagma, tooth wear, tooth contract shape, gingival atrophy etc. causes exposes and causes tooth to sour, sweet, hot and cold and visit to touch to stimulate and produce the sense of aching, and soft sense appears floating in back tooth such as food acids sweet food thing such as Fructus Myricae rubrae, Fructus Vitis viniferae etc.Simultaneously, dental plaque and decayed tooth also are the common odontopathies of people.At present, the Therapeutic Method of such odontopathy has surgery to be aided with Drug therapy etc. usually, but existing method or treatment are complicated, or curative effect is not good enough.
(3) summary of the invention
The technical problem to be solved in the present invention is to provide a kind of effective treatment dentin hypersensitiveness, eliminates dental plaque, the desensitizing anticarious gel of prevention decayed tooth.
The present invention also provides a kind of preparation method of described desensitizing anticarious gel.
Described desensitizing anticarious gel comprises the component of following portions by weight:
Sodium fluoride 1-5 part;
Paraformaldehyde 5-10 part;
Hydroxyethyl-cellulose 3-10 part;
1000 parts in water;
Can accept acid with the pH that keeps described gel at 6～8 human body.
Described paraformaldehyde refers to the low-molecular-weight polyformaldehyde.
Preferably, described desensitizing anticarious gel comprises that also parts by weight are the Folium Stevlae Rebaudianae of 1-5 part.Folium Stevlae Rebaudianae self is a kind of ancillary drug that can be used for the dental disorder treatment.
Preferably, described desensitizing anticarious gel comprises that also parts by weight are the Oleum menthae of 3-10 part.Oleum menthae can play antiinflammatory, refrigerant, flavouring effect.
Preferably, described desensitizing anticarious gel comprises that also parts by weight are the food coloring of 5-10 part.Food coloring is used for toning.
Preferably, described human body can be accepted the sour hydrochloric acid that is.
Most preferably, described desensitizing anticarious gel is made up of the component of following portions by weight:
Sodium fluoride 1-5 part;
Paraformaldehyde 5-10 part;
Hydroxyethyl-cellulose 3-10 part;
1000 parts in water;
Folium Stevlae Rebaudianae 1-5 part;
Oleum menthae 3-10 part;
Food coloring 5-10 part;
Can accept acid with the pH that keeps described gel at 6～8 human body.
The preparation method of described desensitizing anticarious gel comprises the steps:
(1) sodium fluoride, paraformaldehyde are added in the entry dissolves;
(2) add human body and can accept acid, regulator solution pH to 6～8;
(3) add entry and hydroxyethyl-cellulose again, leave standstill and removed bubble in 1～5 day and promptly get described desensitizing anticarious gel.
When desensitizing anticarious gel also contains Folium Stevlae Rebaudianae, Oleum menthae, food coloring, generally in above-mentioned steps (1), add and dissolving.
Desensitizing anticarious gel of the present invention can be with disposable needle tubing packing.During use, earlier gargle or brush teeth with clear water, the cleaning facing, then with the gel squeezing and coating at the facing affected part, remaining silent kept 3-5 minutes.Gargle at last and get final product for 1-2 times.Every day twice, sooner or later respectively once.When using this product, the person of dentin hypersensitiveness can occur as excitement the contact cold water, and along with the increase of access times, this kind sensation weakens gradually, until disappearance, promptly shows that dentin hypersensitiveness eliminates this moment.If caries prevention or enhancing tooth capacity antacid do not have above-mentioned sensation, but must use more than the week continuously when using this product.Often result of use is better.
The present invention has adopted iontophoretic injection mechanism, make active substance sodium fluoride can infiltrate enamel and dentin deep layer fast with desensitizing anticarious effect, thereby eliminate tooth the sensitivity that stimulates generation is touched in sour-sweet, cold and hot and spy, and the floating soft sense that tooth occurs behind the food acids sweet food thing, strengthen the capacity antacid of tooth, control dental caries bacterium is adsorbed to facing, has tangible desensitization, anticaries action.
(4) specific embodiment
The invention will be further described below in conjunction with embodiment, but protection scope of the present invention is not limited to this.
The preparation of embodiment 1 desensitizing anticarious gel
(1) will dissolve in 5g sodium fluoride, 8g paraformaldehyde, 5g Folium Stevlae Rebaudianae, 5g Oleum menthae, the 10g food coloring adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 5g hydroxyethyl-cellulose, leave standstill and removed bubble in 5 days and promptly get described desensitizing anticarious gel.
The preparation of embodiment 2 desensitizing anticarious gels
(1) will dissolve in 2g sodium fluoride, 6g paraformaldehyde, 4g Folium Stevlae Rebaudianae, 7g Oleum menthae, the 10g food coloring adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 10g hydroxyethyl-cellulose, leave standstill and removed bubble in 5 days and promptly get described desensitizing anticarious gel.
The preparation of embodiment 3 desensitizing anticarious gels
(1) will dissolve in 5g sodium fluoride, the 8g paraformaldehyde adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 5g hydroxyethyl-cellulose, leave standstill and removed bubble in 3 days and promptly get described desensitizing anticarious gel.
The preparation of embodiment 4 desensitizing anticarious gels
(1) will dissolve in 5g sodium fluoride, 10g paraformaldehyde, 1g Folium Stevlae Rebaudianae, 4g Oleum menthae, the 10g food coloring adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 4g hydroxyethyl-cellulose, leave standstill and removed bubble in 4 days and promptly get described desensitizing anticarious gel.
The preparation of embodiment 5 desensitizing anticarious gels
(1) will dissolve in 5g sodium fluoride, 8g paraformaldehyde, 5g Folium Stevlae Rebaudianae, 5g Oleum menthae, the 10g food coloring adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 5g hydroxyethyl-cellulose, leave standstill and removed bubble in 5 days and promptly get described desensitizing anticarious gel.
The preparation of embodiment 6 desensitizing anticarious gels
(1) will dissolve in 4g sodium fluoride, 8g paraformaldehyde, the 5g Folium Stevlae Rebaudianae adding 200g water;
(2) add hydrochloric acid, regulator solution pH is to neutral;
(3) add 800g water and 5g hydroxyethyl-cellulose, leave standstill and removed bubble in 5 days and promptly get described desensitizing anticarious gel.
Application examples
Adopt following method validation embodiment 1～6 to make the curative effect of desensitizing anticarious gel.
Earlier gargle or brush teeth with clear water, the cleaning facing, then with the gel squeezing and coating at the facing affected part, remaining silent kept 5 minutes.Gargle at last 2 times.Every day twice, sooner or later respectively once.
Using embodiment 1～6 to make desensitizing anticarious gel after one week respectively, dentin hypersensitiveness's person's symptom all takes an evident turn for the better, effective percentage 100%.
Claims (8)
1, a kind of desensitizing anticarious gel is characterized in that: the component that comprises following portions by weight:
Sodium fluoride 1-5 part;
Paraformaldehyde 5-10 part;
Hydroxyethyl-cellulose 3-10 part;
1000 parts in water;
Can accept acid with the pH that keeps described gel at 6～8 human body.
2, desensitizing anticarious gel as claimed in claim 1 is characterized in that also comprising that parts by weight are the Folium Stevlae Rebaudianae of 1-5 part.
3, desensitizing anticarious gel as claimed in claim 1 is characterized in that also comprising that parts by weight are the Oleum menthae of 3-10 part.
4, desensitizing anticarious gel as claimed in claim 1 is characterized in that also comprising that parts by weight are the food coloring of 5-10 part.
5, desensitizing anticarious gel as claimed in claim 1 is characterized in that it is hydrochloric acid that described human body can be accepted acid.
6, desensitizing anticarious gel as claimed in claim 1 is characterized in that being made up of the component of following portions by weight:
Sodium fluoride 1-5 part;
Paraformaldehyde 5-10 part;
Hydroxyethyl-cellulose 3-10 part;
1000 parts in water;
Folium Stevlae Rebaudianae 1-5 part;
Oleum menthae 3-10 part;
Food coloring 5-10 part;
Can accept acid with the pH that keeps described gel at 6～8 human body.
7, desensitizing anticarious gel as claimed in claim 6 is characterized in that it is hydrochloric acid that described human body can be accepted acid.
8, the preparation method of the described desensitizing anticarious gel of a kind of claim 1 comprises the steps:
(1) sodium fluoride, paraformaldehyde are added in the entry dissolves;
(2) add human body and can accept acid, regulator solution pH to 6～8;
(3) add entry and hydroxyethyl-cellulose again, leave standstill and removed bubble in 1～5 day and promptly get described desensitizing anticarious gel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101546899A CN100464734C (en) | 2006-11-20 | 2006-11-20 | Desensitizing anticarious gel and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101546899A CN100464734C (en) | 2006-11-20 | 2006-11-20 | Desensitizing anticarious gel and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101019821A CN101019821A (en) | 2007-08-22 |
| CN100464734C true CN100464734C (en) | 2009-03-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006101546899A Expired - Fee Related CN100464734C (en) | 2006-11-20 | 2006-11-20 | Desensitizing anticarious gel and its prepn |
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| Country | Link |
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| CN (1) | CN100464734C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860583B (en) * | 2013-01-11 | 2016-03-30 | 山峰 | A kind of preparation method of phenolic resins desensitizer of fluorine-containing potassium |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085423A (en) * | 1992-06-02 | 1994-04-20 | 尤尼利弗公司 | Low stringing toothpaste |
| CN1216461A (en) * | 1996-04-22 | 1999-05-12 | 罗狄亚化学公司 | Toothpaste composition comprising a silica and calcium carbonate based abrasive or additive, compatible with fluorine |
| CN1225818A (en) * | 1998-02-10 | 1999-08-18 | 上海铁路局中心医院 | Safety pulp devitalizer |
| CN1816283A (en) * | 2003-02-04 | 2006-08-09 | 古木林科有限公司 | Compressed resin moderated chewing gum |
-
2006
- 2006-11-20 CN CNB2006101546899A patent/CN100464734C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085423A (en) * | 1992-06-02 | 1994-04-20 | 尤尼利弗公司 | Low stringing toothpaste |
| CN1216461A (en) * | 1996-04-22 | 1999-05-12 | 罗狄亚化学公司 | Toothpaste composition comprising a silica and calcium carbonate based abrasive or additive, compatible with fluorine |
| CN1225818A (en) * | 1998-02-10 | 1999-08-18 | 上海铁路局中心医院 | Safety pulp devitalizer |
| CN1816283A (en) * | 2003-02-04 | 2006-08-09 | 古木林科有限公司 | Compressed resin moderated chewing gum |
Non-Patent Citations (2)
| Title |
|---|
| 口腔用凝胶剂. 李汉源.精细与专用化学品. 1987 |
| 口腔用凝胶剂. 李汉源.精细与专用化学品. 1987 * |
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| Publication number | Publication date |
|---|---|
| CN101019821A (en) | 2007-08-22 |
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Granted publication date: 20090304 Termination date: 20101120 |