CN100448391C - Intraocular tension monitoring device - Google Patents

Intraocular tension monitoring device Download PDF

Info

Publication number
CN100448391C
CN100448391C CNB2007100036605A CN200710003660A CN100448391C CN 100448391 C CN100448391 C CN 100448391C CN B2007100036605 A CNB2007100036605 A CN B2007100036605A CN 200710003660 A CN200710003660 A CN 200710003660A CN 100448391 C CN100448391 C CN 100448391C
Authority
CN
China
Prior art keywords
coil
eyeball
magnon
vibration
monitoring device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CNB2007100036605A
Other languages
Chinese (zh)
Other versions
CN100998496A (en
Inventor
赵家良
王健发
王雪乔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TIANJIN SUOWEI ELECTRONIC TECHNOLOGY Co Ltd
Original Assignee
TIANJIN SUOWEI ELECTRONIC TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TIANJIN SUOWEI ELECTRONIC TECHNOLOGY Co Ltd filed Critical TIANJIN SUOWEI ELECTRONIC TECHNOLOGY Co Ltd
Priority to CNB2007100036605A priority Critical patent/CN100448391C/en
Publication of CN100998496A publication Critical patent/CN100998496A/en
Priority to PCT/CN2007/002278 priority patent/WO2008101374A2/en
Application granted granted Critical
Publication of CN100448391C publication Critical patent/CN100448391C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers

Abstract

An eye pressure monitor is composed of a spectacle frame with coil in it for generating an induced magnetic field, a magnetic vibrator for exciting the vibration of eye ball by external magnetic field and generating an inductive E.M.F in said coil, and a processing module for generating a signal to generate said induced magnetic field, measuring its inductive E.M.F, and sequentially obtaining the vibration information of eye ball, the resonance frequency of cornea and eye pressure.

Description

Intraocular tension monitoring device
Technical field
The present invention relates to a kind of intraocular tension monitoring device, especially a kind of by using the intraocular tension monitoring device of magnetic vibration pick off and resonance principle.
Background technology
Intraocular tension monitoring is significant for glaucomatous diagnosis and treatment at present, especially can carry out the glaucomatous especially diagnosis of device of monitoring in 24 hours and the equipment that medical research presses for to intraocular pressure.
Present known intraocular tension monitoring device mainly contains following three types: implanted, SMD and resonant.It is described as follows:
The first kind: implanted
Such intraocular tension monitoring instrument is implanted one piece of pick off in the anterior chamber, by pick off direct pick-up aqueous humor pressure.Pick off is divided into passive sensor and active sensor two classes.
Passive sensor changes the electric capacity of radio-frequency coil by aqueous humor pressure, thereby changes the radio-frequency coil resonant frequency, can obtain this resonant frequency by the external drive coil, thereby obtain intraocular pressure.Particular content is seen " method formonitoring intraocular pressure using a passive intraocular pressure sensor andpatient worn monitoring recorder " (US6579235, Joseph L.Abita etc, 2000).
Active sensor is handled and the transfer of data chip by implanting one piece of built-in signal, by radio frequency powered, gives outside receptor with the intraocular pressure transfer of data.Particular content is seen " intraocular pressure monitoring/measuringapparatus and method " (US6193656, Robert E.Jeffries etc, 1999).
Second class: SMD
Such intraocular tension monitoring instrument is by corneal contact lens or other devices, pick off is attached to anterior corneal surface, changes (US2004186366), tension force (US5251627) or hardness (US5179953, US4922913A1, US5179953) by the curvature of measuring cornea and obtain the intraocular pressure data.
The 3rd class: resonant
Such intraocular tension monitoring instrument can cause the variation of eyeball resonant frequency by the foundation changing of intraocular pressure.For a unlimited thin spherical shell, its resonant frequency is directly proportional with the square root of intraocular pressure.Such tonometer is instigated eyeball by modes such as audio frequency sound excitation or machine hammer excitations, obtains intraocular pressure by the resonant frequency of measuring cornea or optical fundus.Its main distinction is the mode of pick-up.Mainly contain optical fiber pick-up (US5375595), laser interference pick-up (US2004046937), ultrasonic doppler pick-up (US6030343), capacitor vibration pick-up (Chen Cenghan, resonant non-contact tonometer design is inquired into, Chinese medical apparatus magazine, 1989 the 13rd the 1st phases of volume, p13~16) and Mechanical Contact pick-up modes such as (US6800061, US2003187343).
Above-mentioned three class intraocular tension monitoring devices all have advantage separately, but all have certain defective, have hindered its extensive use clinically.
Wherein implanted intraocular tension monitoring instrument precision is the highest, but it must the anterior chamber of implant patient in, only being suitable for needs to implant lenticular cataract patient.
SMD pick off is subjected to radius of curvature, corneal thickness, the corneal elasticity modulus of cornea to influence bigger; and such intraocular tension monitoring instrument all needs pick off is close to anterior corneal surface by bigger pretightning force with pick off; perhaps need to customize the corneal contact lens that tightly cooperates with patient's anterior corneal surface; daily routines restriction to patient during guarding is more, and is difficult to long-time monitoring.
The pick-up mode of the existing report of resonant intraocular tension monitoring instrument is all to being subjected to the influence of distance and eyelid.As all not measuring resonance signal under the situation of catacleisis by optical fiber pick-up, laser interference pick-up, capacitor vibration pick-up and the pick-up of Mechanical Contact formula, ultrasonic doppler then is difficult to distinguish the vibration of eyelid and the signal that eyeball vibrates when catacleisis.Therefore such intraocular tension monitoring instrument is difficult to realize night guardian.
But research and develop a kind of non-implantation, insensitive to ocular movement, be the equipment of being badly in need of and failing for a long time to develop in diagnosis of glaucoma and the treatment to the intraocular tension monitoring instrument of the little monitoring in night of eyeball compressing.
Summary of the invention
The technical problem to be solved in the present invention is to overcome the deficiencies in the prior art, and a kind of novel intraocular tension monitoring device is provided, have non-implantation, insensitive to ocular movement, little to eyeball compressing, can 24 hours advantages such as on-line monitor.
For solving the problems of the technologies described above, the present invention adopts the basic design of technical scheme to be: a kind of intraocular tension monitoring device, it is characterized in that: described intraocular tension monitoring device comprises spectacle-frame, magnon and processing module, is provided with the coil that energising can produce induced field in the described spectacle-frame; Described magnon is close to eyeball and is instigated the eyeball vibration by the external magnetic field excitation, follows the eyeball vibration simultaneously, and produces induction electromotive force in the coil in spectacle-frame; Described processing module produces signal so that the spectacle-frame interior loop produces induced field, and measures induction electromotive force by magnetic induction principle, obtains the vibration information of eyeball, thereby obtains the resonant frequency of cornea, and then obtain intraocular pressure.
The present invention is in conjunction with the characteristics of SMD and resonant intraocular tension monitoring instrument, it is clipped in magnon and is attached on the cornea in the corneal contact lens, instigate the eyeball vibration by external magnetic field excitation magnon, the vibration of eyeball simultaneously drives the magnon vibration, the magnon vibration can cause the disturbance of external magnetic field again, thereby produces corresponding induction electromotive force in induction coil.Can obtain the cornea vibration information by detecting induction electromotive force, and can therefrom extract resonant frequency, thereby obtain intraocular pressure.
Magnon is that a thin magnet ring is placed two corneal contact lens central authorities, forms a kind of " sandwich " structure, can should " sandwich " structure be assembled into corneal contact lens by ultrasonic bonding or bonding mode.The corneal contact lens of embedded magnet ring and common corneal contact lens using method are similar, can directly be worn on patient's cornea.In order not influence patient's twenty-twenty vision, the magnet ring intermediate demand is reserved the loophole of certain diameter, is the hole of 6mm such as diameter.
Excitation field produces by a coil, and this coil places in the rims of spectacle of a spectacle-frame.Can produce the power of different sizes, frequency and direction to magnon by the electric current of different sizes, frequency and direction.
Processing module of the present invention mainly comprises analog signal processing module, high speed logic processing unit, low-power scm and wireless transport module, use rechargeable battery powered, wherein, the analog signal processing module comprises the importation that is used to produce bias magnetic field signal and excitation field segment signal output and is used for obtaining vibration signal that magnon produces.This processing module can be located on the corner bracket of spectacle-frame.
For measuring coil, the vibration of magnon produces induction electromotive force to excitation coil in excitation coil simultaneously, and the processing by subsequent conditioning circuit can extract the induction electromotive force that is produced by the magnetic vibration vibration.
In order to guarantee the accuracy of exciting and vibration measuring, magnon needs to be close on the cornea in measuring process.The present invention produces bias magnetic field by excitation coil magnet ring is pressed on the cornea.In order accurately to catch resonant frequency and to improve signal to noise ratio, excitation field is how sinusoidal combination field, and it produces by excitation coil by sinusoidal combination voltage signal more than a group.Therefore the voltage that is added on the excitation coil is the combination of driving voltage and bias voltage, and its mathematic(al) representation is as follows:
v = v 0 + Σ k = 0 N - 1 v k cos ( ω k t + Φ k )
V wherein 0For producing the required voltage of bias magnetic field, v kBe the excitation signal amplitude of each Frequency point, ω kBe the frequency of pumping signal, Φ kBe phase place, between [0,2 π], press the normal state random distribution.
The present invention extracts the induction electromotive force that magnon produces by Wheatstone bridge in excitation coil.Wherein, L2 is excitation coil and measurement coil, and L1 is a bucking coil, and both constitute a brachium pontis, and R1 and R2 constitute another brachium pontis.Then:
V 2 = ω L 2 ω L 2 + ω L 1 × ( V o - ΔV ) + ΔV
V 1 = R 2 R 2 + R 1 × V o
Satisfy R 2 R 2 + R 1 = ω L 2 ω L 2 + ω L 1 , And R 2>>R 1,
V 2 - V 1 = ΔV - R 2 R 2 + R 1 × ΔV = R 2 R 2 + R 1 × ΔV ≈ ΔV
The present invention carries out the FFT conversion by the induction electromotive force that the magnon that collects is produced and asks for formant in excitation coil, promptly obtain amplitude frequency spectrum, obtains eyeball resonant frequency f again after single-chip microcomputer is handled, by formula P=k*f 2Obtain intraocular pressure, k wherein is a calibrating parameters.
In the process of measuring intraocular pressure, patient's heart beating also can cause the vibration of eyeball, and therefore this invention also can realize the measurement of palmic rate simultaneously,, can also obtain patient's palmic rate according to the amplitude frequency spectrum of eyeball vibration that is.
After adopting technique scheme, the present invention compared with prior art has following beneficial effect.
Intraocular tension monitoring device of the present invention at first need not to implant in the anterior chamber, and is simple in structure, is convenient to more patient; Secondly insensitive to ocular movement, little to the eyeball compressing, it is more comfortable to make that the patient uses, but monitoring in night in addition makes it realize the seriality of monitoring, better monitoring patients intraocular pressure.
Below in conjunction with accompanying drawing the specific embodiment of the present invention is described in further detail.
Description of drawings
Fig. 1 is the operation principle sketch map of intraocular tension monitoring device of the present invention;
Fig. 2 is the package assembly sketch map of magnon of the present invention;
Fig. 3 is close to the mode of the wearing sketch map of eyeball for the corneal contact lens with embedded magnet ring of the present invention:
Fig. 4 is the oscillogram of pumping signal of the present invention;
Fig. 5 is measuring bridge figure of the present invention;
Fig. 6 is a workflow diagram of the present invention;
Fig. 7 is the amplitude frequency spectrum figure of the present invention's eyeball vibration under incentive condition.
Fig. 8 is system framework figure of the present invention.
In the accompanying drawing: 1, go up corneal contact lens; 2, magnet ring; 21, loophole; 22, groove; 3, following corneal contact lens; 4, magnon; 5, eyeball; 6, spectacle-frame; 61, rims of spectacle; 62, Glasses earpiece; 7, processing module; A, excitation field; B, disturbed magnetic field; C, direction of vibration; f 0, palmic rate; f 1, the eyeball resonant frequency.
The specific embodiment
As shown in Figure 1, intraocular tension monitoring device of the present invention, comprise spectacle-frame 6, magnon 4 and processing module 7, spectacle-frame 6 places the eyes front, processing module 7 is located at the position of close rims of spectacle 61 on the Glasses earpiece 62, magnon 4 is worn on eyeball 5, is provided with the coil that energising can produce induced field in the described spectacle-frame 6; Described magnon 4 is close to eyeball 5 by the external magnetic field excitation and is instigated eyeball 5 vibrations, follows eyeball 5 vibrations simultaneously, and produces induction electromotive force in the coil in spectacle-frame 6; Described processing module 7 produces signal so that spectacle-frame 6 interior loop produce induced field, and measures induction electromotive force by magnetic induction principle, obtains the vibration information of eyeball 5, thereby obtains the resonant frequency of cornea, and then obtain intraocular pressure.
Magnon 4 with the corneal contact lens form among Fig. 1 is worn on eyeball 5 surfaces, be similar to and wear contact lens, the patient wears a pair of glasses frame 6 again, be embedded with excitation in the inside of spectacle-frame and measure coil, measuring coil and excitation coil is same coil, and the pumping signal that processing module 7 produces flows to the coil in the spectacle-frame 6.Coil produces excitation field a and acts on the magnet ring in the magnon 4.Magnon 4 is instigated eyeball 5 and is done vibration with one heart.The vibration of eyeball 5 drives magnon 4 vibrations conversely, and the magnetic field of the vibration meeting disturbance excitation coil of magnon 4 produces induction electromotive force in excitation coil.Processing module 7 is by the induction electromotive force in the specific method detection excitation coil, and this specific method comprises subsequent conditioning circuits processing (consulting Fig. 5 and Fig. 8) such as electric bridge, signal amplification, filtering, thereby obtains eyeball 5 vibration informations.The eyeball vibration information is carried out the amplitude frequency spectrum (consulting Fig. 7) that fft analysis obtains the eyeball vibration, from amplitude frequency spectrum, can obtain patient's palmic rate f at least 0Resonant frequency f with eyeball 1To the resonant frequency processing of tabling look-up, pass through formula P = k * f 1 2 Obtain intraocular pressure.K wherein is a calibrating parameters, can obtain patient's intraocular pressure value.
Its mathematic(al) representation of pumping signal that processing module 7 produces in above-mentioned is as follows:
v = v 0 + Σ k = 0 N - 1 v k cos ( ω k t + Φ k )
V wherein 0For producing the required voltage of bias magnetic field, v kBe the excitation signal amplitude of each Frequency point, ω kBe the frequency of pumping signal, Φ kBe phase place, [0,2 π] between by the normal state random distribution, as shown in Figure 4, be the oscillogram of pumping signal of the present invention, the voltage that produces bias magnetic field in the present embodiment is 4V, the voltage that produces pumping signal is from 1~1000Hz, interval 1Hz, the amplitude of each frequency is 0.1V, and phase place is according to the normal state random distribution.
The induction electromotive force that produces in excitation coil is as follows:
V 2 = ω L 2 ω L 2 + ω L 1 × ( V o - ΔV ) + ΔV
V 1 = R 2 R 2 + R 1 × V o
Satisfy R 2 R 2 + R 1 = ω L 2 ω L 2 + ω L 1 , And R 2>>R 1,
V 2 - V 1 = ΔV - R 2 R 2 + R 1 × ΔV = R 2 R 2 + R 1 × ΔV ≈ ΔV
Wherein, L2 is excitation coil and measurement coil, and L1 is a bucking coil, and both constitute a brachium pontis, and R1 and R2 constitute another brachium pontis, as shown in Figure 5, are the electric bridges that is used to detect induction electromotive force.The enamel-covered wire coiling of excitation and sensor coil L1 employing diameter 0.01mm, totally 100 circles, diameter 30cm.The enamel-covered wire coiling of also adopting the 0.01mm diameter of bucking coil L2, totally 10 circles, diameter 1cm places in the processing module (7).In order to reduce both phase mutual interference, L1 becomes vertical distribution with L2.In order to keep bridge balance, R1 gets 100K Ω, and R2 is a variable resistance.Under the interferential situation of no magnon (4) and external magnetic field, electric bridge is applied pumping signal, adjust R2, make bridge balance, the numerical value among the figure need be decided according to concrete circuit, is not a determined value.
Fig. 2 is the assembling mode of magnon.Magnon 4 is made up of corneal contact lens 3 under corneal contact lens on a slice 1, magnet ring 2 and a slice.The wearing mode of magnon is the same with common soft corneal contact lens usual method, fits on the eyeball and (consults Fig. 3).Two corneal contact lenss 1,3 can customize, and leave the groove 22 that holds magnet ring 2 therein.Also can directly use existing soft corneal contact lens, be assembled into the corneal contact lens of a slice " sandwich " structure by ultrasonic bonding or bonding method.In order to guarantee the rigidity that having of corneal contact lens is certain and not needing to apply bigger preload force that following corneal contact lens 3 must be thinner than corneal contact lens 1.Corneal contact lens 3 thickness are got 0.1mm under in the present embodiment, and last corneal contact lens 1 thickness is got 0.8mm.The thickness of magnet ring 2 is 0.5mm, and external diameter 8mm, internal diameter are the loophole of 6mm, adopts rubidium ferrum B permanent magnetic material.
Fig. 6 is the workflow of intraocular tension monitoring instrument of the present invention.System carries out one-shot measurement every 1 hour or shorter time, and single measurement applies about pumping signal 10s, and the pretension magnetic field described in the figure is the bias magnetic field that bias voltage produces by excitation coil, and purpose is for magnet ring is pressed on the cornea.
Fig. 7 is the eyeball vibration amplitude frequency spectrum that obtains.By electric bridge to signal extracts, amplification, analysis of spectrum can be obtained the patient at least palmic rate and eyeball resonant frequency, so the present invention also can be used to measure patient's palmic rate simultaneously.
Fig. 8 is system framework figure, part in the wherein big frame is a processing module 7, wherein comprise analog signal processing, high speed logic processing unit (using the EP1C3T144C8 of altera), low-power scm (using the MSP430F149 of Ti) and wireless transport module use rechargeable battery powered.
The analog signal processing module comprises input and output two parts.Wherein output channel is used to produce bias magnetic field signal and pumping signal.Single-chip microcomputer is given FPGA with pre-designed offset signal and offset signal data, gives DA by FPGA by high speed logic, through giving excitation coil after the power amplifier.Input channel is used for obtaining the vibration signal that magnon 4 is produced.By electric bridge shown in Figure 5 vibration signal is converted to differential voltage, amplification enters band filter through difference again.The passband of band filter is 40Hz~1KHz, keep palmic rate and eyeball resonant frequency, go because the low frequency signal that the tremor of eyeball nature causes and because the high-frequency signal that the eyelid vibration causes, subsequently FPGA by AD with filtered signals collecting to FPGA inside.
The FFT conversion is in the inner realization of FPGA fast, and through obtaining amplitude frequency spectrum as shown in Figure 7 after 1024 the FFT conversion, FPGA sends 1024 frequency spectrum data into single-chip microcomputer subsequently, gets access to eyeball resonant frequency f after single-chip microcomputer is handled 0With palmic rate f 1So, can pass through formula P = k * f 1 2 Obtain intraocular pressure, k wherein is a calibrating parameters.
In addition, module 7 is obtained after the intraocular pressure, can be stored in single-chip microcomputer inside, and can finish a monitoring cycle or in the monitoring process data are being transferred to data center by wireless module.
Intraocular tension monitoring device of the present invention at first need not to implant in the anterior chamber, and is simple in structure, is convenient to more patient; Secondly insensitive to ocular movement, little to the eyeball compressing, it is more comfortable to make that the patient uses, but monitoring in night in addition makes it realize the seriality of monitoring, better monitoring patients intraocular pressure.

Claims (5)

1, a kind of intraocular tension monitoring device, described intraocular tension monitoring device comprises spectacle-frame, magnon and processing module, be provided with the coil that energising can produce induced field in the described spectacle-frame, it is characterized in that: described magnon is by last, following corneal contact lens and magnet ring are formed, magnet ring places, in the groove that correspondence is provided with between the following corneal contact lens, the pressing structure that is " sandwich " formula, magnon is shaped as and can be buckled in epibulbar spherical crown curve form, described corneal contact lens thickness down is less than last corneal contact lens thickness, magnet ring ringwise, the centre is a loophole, the corresponding respectively lower surface of corneal contact lens and the upper surface of following corneal contact lens be located at of groove, described magnon is close to eyeball and is instigated the eyeball vibration by the external magnetic field excitation, follow the eyeball vibration simultaneously, and produce induction electromotive force in the coil in spectacle-frame, described processing module mainly comprises the analog signal processing module, the high speed logic processing unit, low-power scm and wireless transport module, wherein, the analog signal processing module comprises the importation that is used to produce bias magnetic field signal and excitation field segment signal output and is used for obtaining vibration signal that magnon produces, the induction electromotive force that described magnon vibration signal is produced in coil uses the mode of electric bridge to measure, induction electromotive force carries out the FFT conversion and asks for formant, promptly obtain amplitude frequency spectrum, after handling, single-chip microcomputer obtains eyeball resonant frequency f, by formula P=k*f 2Obtain intraocular pressure, k wherein is a calibrating parameters.
2, a kind of intraocular tension monitoring device according to claim 1 is characterized in that: described coil is excitation coil and measures coil, is located in the rims of spectacle of spectacle-frame excitation coil and the shared coil of measurement coil.
3, a kind of intraocular tension monitoring device according to claim 2 is characterized in that: apply DC voltage in described excitation coil and produce bias magnetic field, use this bias magnetic field that magnon is pressed on eyeball surface.
4, a kind of intraocular tension monitoring device according to claim 3, it is characterized in that: apply the how sinusoidal combination of stimulation of sinusoidal combination voltage signal generation more than group magnetic field in described excitation coil, use this excitation field to act on magnon and instigate the vibration with one heart of eyeball do.
5, a kind of intraocular tension monitoring device according to claim 1 is characterized in that: described intraocular tension monitoring device can also obtain patient's palmic rate according to the amplitude frequency spectrum of eyeball vibration.
CNB2007100036605A 2007-01-23 2007-01-23 Intraocular tension monitoring device Active CN100448391C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CNB2007100036605A CN100448391C (en) 2007-01-23 2007-01-23 Intraocular tension monitoring device
PCT/CN2007/002278 WO2008101374A2 (en) 2007-01-23 2007-07-27 Monitor device for measuring the pressure in the eye

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2007100036605A CN100448391C (en) 2007-01-23 2007-01-23 Intraocular tension monitoring device

Publications (2)

Publication Number Publication Date
CN100998496A CN100998496A (en) 2007-07-18
CN100448391C true CN100448391C (en) 2009-01-07

Family

ID=38257374

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2007100036605A Active CN100448391C (en) 2007-01-23 2007-01-23 Intraocular tension monitoring device

Country Status (2)

Country Link
CN (1) CN100448391C (en)
WO (1) WO2008101374A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7845235B2 (en) 2007-11-06 2010-12-07 Costin Sandu Non-invasive system and method for measuring vacuum pressure in a fluid
EP2319252A2 (en) * 2008-08-29 2011-05-11 Phonak AG Hearing instrument and method for providing hearing assistance to a user
SG181956A1 (en) * 2010-01-05 2012-08-30 Sensimed Sa Intraocular pressure monitoring device
CN101822528B (en) * 2010-05-13 2011-06-29 华中科技大学 Intraocular tension testing device
GB201017637D0 (en) * 2010-10-20 2010-12-01 Univ Dundee Device for monitoring intraocular pressure
US11406415B2 (en) 2012-06-11 2022-08-09 Tenex Health, Inc. Systems and methods for tissue treatment
CN103181750B (en) * 2012-12-21 2015-08-26 苏州苜蓿园电子有限公司 The method of Wearable tonometer and mensuration intraocular pressure thereof
US9962181B2 (en) 2014-09-02 2018-05-08 Tenex Health, Inc. Subcutaneous wound debridement
CN104473615B (en) * 2014-11-11 2015-12-09 华中科技大学 A kind of 24 hours intraocular pressure monitoring sensors based on fiber grating
CN106821305A (en) * 2017-03-23 2017-06-13 清华大学 A kind of intraocular pressure monitoring device
CN112603258B (en) * 2020-12-08 2022-03-25 南京大学 Intelligent contact lens for monitoring intraocular pressure
CN113331785A (en) * 2021-05-12 2021-09-03 清华大学 Wireless flattening type intraocular pressure monitoring system
CN113712539B (en) * 2021-08-31 2023-11-14 刘宏图 Intelligent healthy glasses for children
CN113867006B (en) * 2021-09-28 2023-04-28 电子科技大学 Gamma-Fe-based 2 O 3 Flexible multifunctional cornea contact lens of@NiO magnetic oxide nanosheets
CN113974553B (en) * 2021-12-28 2022-04-01 广东麦特维逊医学研究发展有限公司 Eye pressure measuring device and working method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840041A (en) * 1994-09-16 1998-11-24 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Device for measuring the mechanical properties of biological tissue
CN1511009A (en) * 2001-03-30 2004-07-07 ѧУ�����絾���ѧ Method and device for measuring intraocular tension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209021A (en) * 1977-12-22 1980-06-24 J. D. Moller Optische Werke Gmbh Apparatus for generating and measurement of defined forces for medical appliances
CN2296693Y (en) * 1997-07-14 1998-11-11 河南省眼科研究所 Light electronic intraocular pressure tracer
US6093147A (en) * 1999-02-22 2000-07-25 Kontiola; Antti Apparatus for measuring intraocular pressure
SE9903099L (en) * 1999-08-31 2000-11-13 Anders Eklund Method and apparatus for determining intraocular pressure, using the change in frequency characteristic

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840041A (en) * 1994-09-16 1998-11-24 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Device for measuring the mechanical properties of biological tissue
CN1511009A (en) * 2001-03-30 2004-07-07 ѧУ�����絾���ѧ Method and device for measuring intraocular tension

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
A Magnetic Sensors Feasibility Investigation for ContinousIntraocular Pressure Monitoring. Bertoncini F et al.Sensors for Industry Conference. 2002
A Magnetic Sensors Feasibility Investigation for ContinousIntraocular Pressure Monitoring. Bertoncini F et al.Sensors for Industry Conference. 2002 *
Intraocular pressure sensors: analysis of a passivedeviceapproach. Giannetti R et al.IEEE Instrumentation and Measurement Technology Conference,Vol.2 . 2003
Intraocular pressure sensors: analysis of a passivedeviceapproach. Giannetti R et al.IEEE Instrumentation and Measurement Technology Conference,Vol.2 . 2003 *

Also Published As

Publication number Publication date
WO2008101374A2 (en) 2008-08-28
CN100998496A (en) 2007-07-18
WO2008101374A3 (en) 2009-08-27

Similar Documents

Publication Publication Date Title
CN100448391C (en) Intraocular tension monitoring device
Katuri et al. Intraocular pressure monitoring sensors
EP2629658B1 (en) Device for monitoring intraocular pressure
US20090076367A1 (en) Monitoring Intraocular Pressure
CA2264193C (en) A tonometer system for measuring intraocular pressure by applanation and/or indentation
US6890300B2 (en) Implantable microscale pressure sensor system for pressure monitoring and management
EP1126781B1 (en) Method and apparatus for signal transmission and detection using a contact device
US20180368682A1 (en) Ophthalmic lens with intraocular pressure monitoring system
CN103576336A (en) Neuromuscular sensing for variable-optic electronic ophthalmic lens
EP1311187A1 (en) System for measuring intraocular pressure of an eye and a mem sensor for use therewith
WO2009100439A2 (en) Pressure monitor
Piso et al. Modern monitoring intraocular pressure sensing devices based on application specific integrated circuits
CN101268929B (en) Method and device for determining the intraocular pressure, by measuring the changing of the frequency characteristics
WO2014018294A1 (en) Pressure monitor
CN112603258B (en) Intelligent contact lens for monitoring intraocular pressure
CN219229843U (en) Intraocular pressure monitoring system
CN113331785A (en) Wireless flattening type intraocular pressure monitoring system
AU758525B2 (en) A tonometer system for measuring intraocular pressure by applanation and/or indentation
Katuri Design and Optimization of Passive Wireless Intraocular Pressure Sensor
CN116999020A (en) Continuous intraocular pressure detection device and measurement method thereof
CN117017206A (en) Intraocular pressure measuring device
Blue et al. MEMS-based wireless intraocular pressure sensors
MXPA99002157A (en) A tonometer system for measuring intraocular pressure by applanation and/or indentation

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant