CN100438892C - Chinese traditional medicine for treating nerve deafness and its preparation process - Google Patents
Chinese traditional medicine for treating nerve deafness and its preparation process Download PDFInfo
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- CN100438892C CN100438892C CNB2006100376138A CN200610037613A CN100438892C CN 100438892 C CN100438892 C CN 100438892C CN B2006100376138 A CNB2006100376138 A CN B2006100376138A CN 200610037613 A CN200610037613 A CN 200610037613A CN 100438892 C CN100438892 C CN 100438892C
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Abstract
The present invention relates to a Chinese traditional medicine for treating nerve deafness and a preparation process. The present invention explores and researches the pathogenesis of nerve deafness from the angle of traditional Chinese medicine, and deems that the functional disorder of internal organs, disharmony between QI and blood and the blood blocking and the nutrition loss of venation are the internal causes of the nerve deafness, while the inducement of disadvantage factors is the external cause of the nerve deafness. The principal raw materials of the composite medicament of the present invention are screened carefully from red peony root, white peony root, Chinese angelica root, spicebush root, accumulated shell, astragalus root, red sage root, hemlock parsley, musk and honeysuckle, wherein the principal raw materials are proportioned reasonably according to weight share, and then are respectively rolled, ground and sieved in batches to be made into powder by mixing and sieving according to order or refined into pills by honey preparation. The medicament of the present invention is developed by referencing the theory of modern medicine on the basis of recipes handed down from ancestors, and has the advantages of peculiar recipe, favorable therapeutic efficacy, high cure rate and relatively short course of treatment after the verification of hundreds of examples. With safe and non-toxic property, the medicament of the present invention can treat both the manifestation and root causes of nerve deafness of patients.
Description
Technical field:
The present invention relates to treat deaf medicine, particularly is Chinese formulated products of raw material for treating nerve deafness and preparation method thereof with the Chinese medicinal herbs.
Background technology:
At present, generally deafness is divided into three kinds of transmission deafnesses, sensorineural deafness, mixed deafness clinically.To be sound wave enter whole acoustic process that back, desire arrive the internal ear oval window from external auditory meatus to transmission deafness is blocked and cause due to the sound wave conduction weakens; Sensorineural deafness claims nerve deafness again, is that extraneous sound wave can not import internal ear into and arrives cochlea, or cochlea can not acoustic, acoustic nerve can not phonosensitive due to.Comparatively speaking, nerve deafness is the most common, cause the reason of nerve deafness a lot: congenital aplasia of inner ear is arranged, there have acquired infection to cause to be deaf, there have drug intoxication to cause to be deaf, there is wound to cause deaf or sudden deafness, presbyacusis, undulatory property deafness, central deafness, FHL or the like.The patient has not had audition or audition very poor, then directly influences quality of life, and body and mind is very worried.The deaf main methods such as acupuncture, physical therapy, intravenous injection, oral ERLONG WAN that adopt of treatment now.The purpose of acupuncture, physical therapy is in order to stimulate ear's nervous system, and intravenous injection, oral drugs all are to reach with blood vessel dilating that to recover ear's nervous system be purpose.On the whole, the method for treatment deafness now is few, medicine is also few, and curative effect is long, curative effect is not good enough yet.
Summary of the invention:
The object of the present invention is to provide a kind of treatment deaf, particularly the Chinese formulated products of nerve deafness.
Another object of the present invention provides the preparation method of medicament in the above-mentioned treatment nerve deafness.
Technical solution of the present invention is the pathogeny of the deaf disease of therefrom medical angle exploratory development, and it is foster to think that its endogenous cause of ill is visceral dysfunction, disharmony between QI and blood, venation blood hinders mistake; Exopathogenic factor is to be subjected to due to the inducing of unfavorable factor.Thereby the palpus treating both the principal and secondary aspects of a disease, simultaneously also will be with reference to the achievement in research of modern pharmacology, filtering out multiple Chinese herbal medicine cautiously is raw material, with its rational proportion, the Chinese formulated products that is prepared into the treatment nerve deafness meticulously is applied to clinical.
The primary raw material of the medicament combination of the careful choosing of the present invention is: Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, Fructus Aurantii, the Radix Astragali, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Moschus, Flos Lonicerae.
Medicament of the present invention is made up of following weight portion proportioning:
Radix Paeoniae Rubra 15～30, the Radix Paeoniae Alba 10～30, Radix Angelicae Sinensis 10～20, the Radix Linderae 10～20, Fructus Aurantii 10～20, the Radix Astragali 15～30, Radix Salviae Miltiorrhizae 10～30, Rhizoma Chuanxiong 10～20, Moschus 5～6, Flos Lonicerae 10～30.
Pharmaceutical formulation preferred weight part ratio range of the present invention is:
Radix Paeoniae Rubra 15～25, the Radix Paeoniae Alba 12～20, Radix Angelicae Sinensis 15～20, the Radix Linderae 15～20, Fructus Aurantii 10～15, the Radix Astragali 20～30, Radix Salviae Miltiorrhizae 15～25, Rhizoma Chuanxiong 15～20, Moschus 5～5.5, Flos Lonicerae 15～30.
Medicaments preparation method of the present invention is: choose and state qualified medical material and weigh and assort, roll fine lapping in batches respectively, sieve, mix in due order in batches, sieve powder or add refined honey honey again and refine into pill, its preparation process is:
(1) requires weighing and burden by weight;
(2) in batches, pulverize separately rolls fine lapping and sieves: Fructus Aurantii, Radix Salviae Miltiorrhizae, Moschus are pulverized porphyrize one by one, cross 100～120 mesh sieves respectively; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, Rhizoma Chuanxiong rolled jointly be fine into powder, cross 80～100 mesh sieves; Flos Lonicerae rolled be fine into powder, cross 80～100 mesh sieves with standby;
(3) uniform mixing grinds and to sieve in due order: the Moschus fine powder is divided into fourth class deal, each aliquot each and Fructus Aurantii; With Radix Salviae Miltiorrhizae; With Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, Rhizoma Chuanxiong Six-element medicine; With Flos Lonicerae, to grind, each crosses 100～120 mesh sieves, and then all medicamental pulverata are evenly mixed, whole mistake 100～120 mesh sieves.
More than be prepared into the powder of Chinese patent medicine of the present invention.
(4) honey is smelt ball: get above-mentioned powder medicamental pulverata and with the ratio of its weight be that 1: 1 refined honey evenly rubs up mutually and makes moist agglomerate, be compression molded into ball.
Beneficial effect of the present invention:
(1) the sharp clearing away heat and cooling blood of the energy of the Radix Paeoniae Rubra in the drug regimen of the present invention, promoting blood circulation and detumescence; The Radix Paeoniae Alba has nourishing blood for regulating menstruation, the effect of suppressing the hyperactive liver analgesic; Radix Angelicae Sinensis have enrich blood, the effect of promoting blood circulation and stopping pain; Radix Linderae energy promoting the circulation of QI to relieve pain; The effect that Fructus Aurantii has dispersing the stagnated live-QI to relieve the stagnation of QI, removing food stagnancyization to stagnate; The Radix Astragali has QI invigorating, lets out the dense effect of poison row; Radix Salviae Miltiorrhizae energy nourishing blood to tranquillize the mind, activating blood circulation to dissipate blood stasis; Rhizoma Chuanxiong have invigorate blood circulation have a respite, the effect of wind-expelling pain-stopping; Moschus has the refreshment of having one's ideas straightened out, promoting blood circulation and detumescence analgesic effect; Flos Lonicerae energy heat-clearing and toxic substances removing has tangible antibacterial action.The reasonable compatibility that this medicine is formed can conditioning viscera, strengthening the body resistance, opening the orifice and activating blood circulation, dampness removing collateral dredging, YIN nourishing soothing liver-QI, regulate neurally, can reach the purpose for the treatment of both the principal and secondary aspects of a disease to the deafness disease patient.
(2) to be applied to clinical efficacy obvious for medicament of the present invention.So far accept 700 routine nerve deafness patients once for medical treatment from 1999 the applicant, be divided into treatment group, matched group at random.The treatment group is used this pharmaceutical treatment, the oral commercially available ERLONG WAN of matched group.Two groups of observations of carrying out clinical effectiveness equally after the treatment through 45 days three courses of treatment relatively, the cure rate of treatment group is 87.78%, total effective rate is 91.11%, the cure rate of matched group is 20%, total effective rate is 68%.Analyzing and processing by statistics, two groups have significant difference (P＜0.01).
Explanation its original curative effect more now gives an actual example:
(1) patient Hu (woman), 58 years old, household Huai Huaiyin District bureau of labour dormitory area.Because of suffering from sudden deafness, binaural listening descends, in ear continues that the cicada cried sound, when districts and cities the People's Hospital department of otorhinolaryngology expert diagnosis is a sudden deafness, doctor trained in Western medicine is done Hyperbaric oxygen chamber and oral commercially available ERLONG WAN and other Pimobendane thing treatment January, and binaural listening does not recover yet, after take two courses of treatment of this medicament, audition is recovered substantially, and tinnitus is discontinuity, recovers normal fully in 45 days.
(2) patient tall certain (man), 26 years old, Xu Yang village, emerging town, household Yancheng City Jianhu County.16 years causes excessive binaural listening that causes of injection streptomycin that suffers from an inflammation of the lungs is become deaf, and deaf, tinnitus reaches 16 years, province institute be diagnosed as the drug intoxication induced deafness and treat do not get better January change after, obey medicament of the present invention January, audition obviously rises 45 decibels, continues again to treat January, and it is normal that audition is recovered substantially.
(3) patient Hu (man), 42 years old, virtuous official country worthy official primary school teaches in the Shuyang County, the Spring Festival is by the fried deaf ears of firecrackers sound, hearing test on average descends 100～110 decibels, all be diagnosed as the knock tendency nerve deafness through provinces and cities' various big hospital, obey commercially available ERLONG WAN certainly and other Pimobendane thing is failed to respond to any medical treatment, through taking medicine of the present invention January, audition is on average recovered 45 decibels, the bimester after audition recover normal substantially.
(3) medicine of the present invention is that (the applicant practises medicine from generation to generation on the basis of secret prescription handed down in the family from generation to generation, specially control ear, nose, larynx) develop with reference to modern medical theory, the prescription uniqueness, therapeutic effect is good, cure rate is high, the course of treatment is short relatively, and safety non-toxic, need not decoct taking convenience.
The specific embodiment:
Select good grade medical material, weigh by weight, proportioning: Radix Paeoniae Rubra 20, the Radix Paeoniae Alba 16, Radix Angelicae Sinensis 18, the Radix Linderae 18, Fructus Aurantii 12, the Radix Astragali 25, Radix Salviae Miltiorrhizae 22, Rhizoma Chuanxiong 18, Moschus 5.3, Flos Lonicerae 20, promptly take by weighing Radix Paeoniae Rubra 200 gram, the Radix Paeoniae Alba 160 grams, Radix Angelicae Sinensis 180 grams, the Radix Linderae 180 grams, Fructus Aurantii 120 grams, the Radix Astragali 250 grams, Radix Salviae Miltiorrhizae 220 grams, Rhizoma Chuanxiong 180 grams, Moschus 53 grams, Flos Lonicerae 200 grams and make raw material, in order to make powder or pill.
The preparation method of powder of the present invention is:
(1), crosses 100～120 mesh sieves respectively with Fructus Aurantii, Radix Salviae Miltiorrhizae, Moschus pulverize separately porphyrize;
(2) Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, Rhizoma Chuanxiong are rolled thin levigation jointly and cross 80～100 mesh sieves;
(3) Flos Lonicerae is rolled thin levigation, cross 80～100 mesh sieves;
(4) the Moschus fine powder is divided into fourth class deal, a copy of it and Fructus Aurantii blend and ground 100～120 mesh sieves again; Portion is with the Radix Salviae Miltiorrhizae blend and ground 100～120 mesh sieves again; Portion is with Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, the medicine blend of Rhizoma Chuanxiong Six-element and ground 100～120 mesh sieves again; Portion is with the Flos Lonicerae blend and ground 100～120 mesh sieves again;
(5) above all medicamental pulverata are fully mixed, whole mistake 100～120 mesh sieves, pack according to quantity.
Pill preparation method of the present invention is:
(1) takes by weighing refined honey 1740 grams
(2) the refined honey temperature is transferred to about 110 ℃, the medicamental pulverata temperature is heated to about 100 ℃.
(3) above-mentioned refined honey and medicamental pulverata are mixed evenly rub into the profit agglomerate, be compression molded into pill immediately.
During the clinical use of the present invention, need according to conditions of patients difference, take as one feels fit.
Claims (7)
1, a kind of Chinese formulated products for the treatment of nerve deafness is characterized in that: it is to be made by following weight parts proportion raw material medicine: Radix Paeoniae Rubra 15～30, the Radix Paeoniae Alba 10～30, Radix Angelicae Sinensis 10～20, the Radix Linderae 10～20, Fructus Aurantii 10～20, the Radix Astragali 15～30, Radix Salviae Miltiorrhizae 10～30, Rhizoma Chuanxiong 10～20, Moschus 5～6, Flos Lonicerae 10～30.
2, a kind of Chinese formulated products for the treatment of nerve deafness according to claim 1, it is characterized in that: the weight portion proportioning of crude drug is: Radix Paeoniae Rubra 15～25, the Radix Paeoniae Alba 12～20, Radix Angelicae Sinensis 15～20, the Radix Linderae 15～20, Fructus Aurantii 10～15, the Radix Astragali 20～30, Radix Salviae Miltiorrhizae 15～25, Rhizoma Chuanxiong 15～20, Moschus 5～5.5, Flos Lonicerae 15～30.
3, a kind of Chinese formulated products for the treatment of nerve deafness according to claim 1 and 2, it is characterized in that: the weight portion proportioning of crude drug is: Radix Paeoniae Rubra 20, the Radix Paeoniae Alba 16, Radix Angelicae Sinensis 18, the Radix Linderae 18, Fructus Aurantii 12, the Radix Astragali 25, Radix Salviae Miltiorrhizae 22, Rhizoma Chuanxiong 18, Moschus 5.3, Flos Lonicerae 20.
4, a kind of Chinese formulated products for the treatment of nerve deafness according to claim 1 is characterized in that: also add the adjuvant refined honey in the preparation process.
5, according to claim 1,2 or 3 described a kind of Chinese formulated productses for the treatment of nerve deafness, it is characterized in that: described Chinese formulated products is powder or pill.
6, a kind of according to claim 1,2 or 3 described a kind of preparation methoies for the treatment of the Chinese formulated products of nerve deafness, it is characterized in that: get qualified medical material and weigh and assort, roll fine lapping in batches respectively, sieve, mix in due order in batches, sieve powder or again honey refine into pill, its preparation process is:
(1) requires weighing and burden by weight;
(2) in batches, pulverize separately rolls fine lapping and sieves: Fructus Aurantii, Radix Salviae Miltiorrhizae, Moschus are pulverized porphyrize one by one, cross 100～120 mesh sieves respectively; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, Rhizoma Chuanxiong rolled jointly be fine into powder, cross 80～100 mesh sieves; Flos Lonicerae rolled be fine into powder, cross 80～100 mesh sieves with standby;
(3) uniform mixing grinds and to sieve in due order: the Moschus fine powder is divided into fourth class deal, each aliquot each and Fructus Aurantii; With Radix Salviae Miltiorrhizae; With Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Radix Linderae, the Radix Astragali, Rhizoma Chuanxiong Six-element medicine; With Flos Lonicerae, to grind, each crosses 100～120 mesh sieves, and then all medicamental pulverata are evenly mixed, and whole mistake 100～120 mesh sieves make powder; Or (four) honey is smelt ball: get above-mentioned powder medicamental pulverata and with the ratio of its weight be that 1: 1 refined honey evenly rubs up mutually and makes moist agglomerate, be compression molded into ball.
7, a kind of preparation method for the treatment of the Chinese formulated products of nerve deafness according to claim 6, it is characterized in that: medicamental pulverata and refined honey evenly rub up the refined honey temperature mutually and transfer to about 110 ℃, and the medicamental pulverata temperature is heated to about 100 ℃.
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100376138A CN100438892C (en) | 2006-01-01 | 2006-01-01 | Chinese traditional medicine for treating nerve deafness and its preparation process |
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2006100376138A CN100438892C (en) | 2006-01-01 | 2006-01-01 | Chinese traditional medicine for treating nerve deafness and its preparation process |
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| CN100438892C true CN100438892C (en) | 2008-12-03 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102861154B (en) * | 2012-09-25 | 2013-11-20 | 康军阳 | Traditional Chinese medicine for treating nerve deafness |
| CN103919844A (en) * | 2014-04-28 | 2014-07-16 | 北京首大耳鼻喉医院 | Traditional Chinese medicine composition for treating nerve deafness as well as preparation method and application thereof |
| CN105168998A (en) * | 2015-08-14 | 2015-12-23 | 李选民 | Traditional Chinese medicine treating spleen and stomach weakness nerve deafness and preparation method therefor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1103795A (en) * | 1993-12-13 | 1995-06-21 | 西安市中心医院 | Herb medicine tablet for curing dizziness and deaf disease |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1103795A (en) * | 1993-12-13 | 1995-06-21 | 西安市中心医院 | Herb medicine tablet for curing dizziness and deaf disease |
Non-Patent Citations (2)
| Title |
|---|
| 感音神经性聋中医中药研究进展. 宣伟军等.中国中西医结合耳鼻咽喉科杂志，第11卷第5期. 2003 |
| 感音神经性聋中医中药研究进展. 宣伟军等.中国中西医结合耳鼻咽喉科杂志，第11卷第5期. 2003 * |
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