CN100427920C - Tester for centrifugal blood integredient specific - Google Patents
Tester for centrifugal blood integredient specific Download PDFInfo
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- CN100427920C CN100427920C CNB2004100427395A CN200410042739A CN100427920C CN 100427920 C CN100427920 C CN 100427920C CN B2004100427395 A CNB2004100427395 A CN B2004100427395A CN 200410042739 A CN200410042739 A CN 200410042739A CN 100427920 C CN100427920 C CN 100427920C
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- specific volume
- centrifugal
- blood component
- photoelectric sensor
- blood
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Abstract
The present invention relates to a centrifugal type blood composition specific volume measurement device which is composed of a power supply system, a centrifugal separation system, a measurement system and a control system, wherein the power supply system comprises a transformer and a power panel; the centrifugal separation system is composed of a direct current motor, a driver, a tray and a protecting cover, the measurement system is composed of a capillary cavity body, a step motor, a screw rod, a photosensor and a circuit board of the measurement system, and the control system is composed of a circuit board of the control system and a liquid crystal display screen. When the present invention is used for measurement, a capillary pipe of trace blood after centrifugal lay separation is arranged in the capillary cavity body with a slit; a screw rod mechanism is driven by the step motor, so the photosensor scans along the slit. The length of a blood composition column and the length of an entire liquid column after separation are accurately measured, and according to the definition of specific volume, the specific volume value of the composition in the blood is calculated; the specific volume value is corrected in the device via a linear regression method, and a final result within the range of an allowable error is obtained.
Description
Technical field
The invention belongs to medical instruments field, is the device that the specific volume of various compositions in the blood is measured.
Background technology
Blood is the important component part of human body, and the various blood components in the blood all have different functions.Play the oxygen effect of taking such as red blood cell, in operation, the numerical value of packed cell volume (Hct) is that the doctor judges whether patient needs an important indicator of transfusing blood.At present, the clinical anesthesia doctor mainly carries out centrifuging by high speed tabletop centrifuge to the micro blood in the kapillary, obtains the Hct value according to Hct definition with vernier caliper measurement, calculating or by the hematocrit reading dial then.Obtaining Hct need divide two steps to realize with two kinds of different equipment at every turn.
Existing high speed tabletop centrifuge profile heaviness, volume is big, and the noise that produces when carrying out high speed centrifugation is big, usually greater than 70dB, has disturbed the staff's who comprises surgical doctor, anesthesia doctor, operating nurse in the operating room operate as normal to a great extent.Simultaneously because the noise decibel is higher, working under this kind environment for a long time has very big influence to staff healthy.
Measure the blood component specific volume with vernier caliper and hematocrit reading dial, when differentiating each adjacent composition interphase, depend on human eye identification, influenced by human factor, the measurement result consistance is bad, and error is big.
Measure the blood component specific volume with existing centrifugal method, whole process is all manual, and the stochastic error of operating process is big, and efficient is low, and the data of measuring need manual record and calculate, and are not easy to statistical study and management.
Summary of the invention
The purpose of this invention is to provide a kind of determinator that can use at the composition of the monitoring of blood at any time specific volume in places such as operating room, this device can use the blood of trace to measure automatically.
The technical solution that realizes the object of the invention is a kind of centrifugal blood component specific volume determinator: this device is made up of power-supply system, centrifugal separation system, measuring system and control system four systems.Wherein power-supply system comprises transformer and power panel; Centrifugal separation system is made up of direct current generator, driver, pallet, protective cover; Measuring system is made up of capillary cavity, stepper motor, screw mandrel, photoelectric sensor, measuring system circuit board; Control system is made up of control system circuit board, LCDs, button.
Centrifugal separation system adopts direct current generator, and micro-blood sample is carried out high speed centrifugation, and a plurality of grooves that are radial arrangement from the center are arranged on the centrifugal pallet.The kapillary shutoff that will fill blood sample to be measured when carrying out centrifugally operated is good, is positioned in the groove on the centrifugal pallet, presses steady kapillary protective cover, selects suitable rotating speed and time to carry out centrifugally operated as required.
Kapillary with the micro blood after the centrifugal layering when measuring is positioned in the capillary cavity that has slit, drives screw body with stepper motor photoelectric sensor is scanned along slit.Because the blood component transmittance difference of plug, each layering in the optoelectronic scanning process, according to the order and the amplitude variation of receiving tube received signal, is judged several medium critical surfaces.Because the stepper motor step distance is accurately design, by calculating in every kind of medium, the step number of advancing of motor just can record the length of each fluid column.By the length of the blood component post after the accurate mensuration separation and the length of whole liquid post, calculate the bulking value of this blood component in the blood according to the definition of specific volume.
Adopt single-chip microcomputer that centrifugal rotational speed, centrifugation time, measuring speed are accurately controlled, measurement result is calculated, writes down, edits, put in order, and blood samples of patients composition specific volume variation tendency in the intuitive manner statement surgical procedure such as available figure.
The centrifugal speed that traditional blood component specific volume assay method adopts is 12000 rev/mins, and centrifugation time is 5 minutes, measures the goldstandard of Hct as micromethod.The present invention selects for use direct current generator to carry out centrifuging, centrifugal rotational speed and centrifugation time are adjustable, measurement result and traditional measurement method measurement result have good linear relationship, adopt linear regression statistical analysis method that measurement data is carried out fitting correction, make the final measurement data that shows and traditional measurement result error less than 3%.
Compared with prior art, the present invention has following significant superior function:
1. adopt up-to-date dc motor technology, overcome common in the past alternating current generator noise, and the complete machine height is reduced, centrifugal radius reduces, and finally makes complete machine small and exquisite, and rotating speed reduces simultaneously, makes operate as normal noise＜60dB;
2. measure the specific volume that calculates each blood component automatically by the mode of optoelectronic scanning, time is short, good reproducibility, the result can divide into groups to carry out long-term storage, editor, put in order, thumbs, and the specific volume that available visual picture shows each blood component of patient in the surgical procedure is trend over time;
3. by the linear regression analysis method complete machine is proofreaied and correct, proofreaied and correct back overall measurement error＜3%.
The present invention has integrated the blood component centrifuging and each blood component specific volume is measured two functions automatically, has improved the practical value of product.Adopt the mode of optoelectronic scanning to measure each blood component specific volume of calculating automatically, by linear regression analysis complete machine is proofreaied and correct, and come the management data result, improved work efficiency greatly, alleviated anesthesia doctor's work load by computing machine.
Description of drawings
Kapillary after the layering of Fig. 1 centrifugal blood;
The centrifugal pallet sectional view of Fig. 2;
Fig. 3 capillary cavity figure;
Fig. 4 measuring system structural representation;
Fig. 5 screw mandrel drives slide block and sensor movement synoptic diagram;
Fig. 6 gear and cog belt driving block and sensor movement synoptic diagram;
Fig. 7 tooth bar driving block and sensor movement synoptic diagram.
Among the figure:
The 1-plug;
The 2-red blood cell;
3-blood plasma;
The 4-air;
The 5-groove;
The centrifugal pallet of 6-;
7-kapillary cavity;
The 8-slit;
The 9-kapillary;
The 10-support;
The 11-photoelectric sensor;
12-capillary cavity;
The 13-position transducer;
The 14-screw mandrel;
The 15-guidepost;
The 16-slide block;
The 17-spring coupling;
The 18-vibroshock;
The 19-stepper motor.
Embodiment
Below in conjunction with Figure of description explanation embodiments of the invention.
Embodiment 1:
The centrifugal motor of centrifugal separation system is selected dc brushless motor for use, also can select the drag cup motor for use.
Embodiment 2:
In the measuring system structure as shown in Figure 4, with axle concentric be connected of constant pitch screw mandrel 14 with stepper motor 19, photoelectric sensor 11 is installed on the removable slide block 16 that is connected with screw mandrel, the rotation of stepper motor 19 is converted to the rectilinear motion of slide block 16 and photoelectric sensor 11 by screw mandrel 14, makes photoelectric sensor 11 along capillary cavity 12 scannings with narrow gap; Two limit of sports record points up and down at photoelectric sensor 11 are installed two position transducers 13, find out extreme position, conjunction measuring work.
Embodiment 3:
Photoelectric sensor can be selected integrated optocoupler for use, also can select separation emission, receiving trap separately for use.
Embodiment 4:
The drive mechanism of photoelectric sensor can be selected for use: silk pole as shown in Figure 5 drives slide block and sensor movement mode; Gear as shown in Figure 6 and cog belt driving block and sensor movement mode; Multiple structures such as tooth bar driving block as shown in Figure 7 and sensor movement mode.
Determinator of the present invention can be of wide application, the embodiment and the application that are not limited in this instructions to be mentioned.For the professional in present technique field, any improvement that the embodiment of the invention is made or change can not exceed the protection domain of spirit of the present invention and claims.
Claims (6)
1. centrifugal blood component specific volume determinator, it is characterized in that: this device is made up of power-supply system, centrifugal separation system, measuring system and control system four systems, and described power-supply system comprises transformer and power panel; Described centrifugation systems is made up of dc brushless motor, driver, pallet, protective cover, operating noise＜60dB; Described measuring system is made up of capillary cavity, stepper motor, screw mandrel, photoelectric sensor, measuring system circuit board, adopt single-chip microcomputer that measurement result is calculated, write down or edits, adopt linear regression statistical analysis method that measurement data is carried out fitting correction, described capillary cavity has slit; Described control system is made up of control system circuit board, LCDs, button.
2. centrifugal blood component specific volume determinator according to claim 1, it is characterized in that: photoelectric sensor is selected integrated optocoupler for use.
3. centrifugal blood component specific volume determinator according to claim 1 is characterized in that: photoelectric sensor is selected separation emission, receiving trap separately for use.
4. centrifugal blood component specific volume determinator according to claim 1 is characterized in that: the drive mechanism of photoelectric sensor selects for use screw mandrel to drive the mode of motion of slide block and sensor.
5. centrifugal blood component specific volume determinator according to claim 1, it is characterized in that: the drive mechanism of photoelectric sensor is selected the mode of motion of gear and gear driven driving block and sensor for use.
6. centrifugal blood component specific volume determinator according to claim 1, it is characterized in that: the drive mechanism of photoelectric sensor is selected the mode of motion of tooth bar driving block and sensor for use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100427395A CN100427920C (en) | 2004-05-25 | 2004-05-25 | Tester for centrifugal blood integredient specific |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100427395A CN100427920C (en) | 2004-05-25 | 2004-05-25 | Tester for centrifugal blood integredient specific |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1584546A CN1584546A (en) | 2005-02-23 |
| CN100427920C true CN100427920C (en) | 2008-10-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100427395A Expired - Fee Related CN100427920C (en) | 2004-05-25 | 2004-05-25 | Tester for centrifugal blood integredient specific |
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| Country | Link |
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| CN (1) | CN100427920C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109932284A (en) * | 2019-03-15 | 2019-06-25 | 上海市嘉定区中心医院 | A kind of hemorheology batch detector methods of optimization |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009040525B4 (en) * | 2009-09-08 | 2015-02-05 | Andreas Hettich Gmbh & Co. Kg | Centrifuge for separating whole blood into blood components, and fluidically communicating containers for insertion into the centrifuge, and methods for obtaining a highly enriched platelet concentrate from whole blood |
| CN103558152B (en) * | 2013-11-14 | 2015-11-18 | 江苏英诺华医疗技术有限公司 | A kind of rapid whole blood platelet aggregation pick-up unit and method |
| CN110780062A (en) * | 2019-11-12 | 2020-02-11 | 翟庆 | Centrifugal blood component specific volume measuring device for anesthesia department |
| CN111504207A (en) * | 2020-06-09 | 2020-08-07 | 四川九八村信息科技有限公司 | Blood cell centrifugal layering detection system and method |
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| DE3342428A1 (en) * | 1983-11-24 | 1985-06-05 | Heraeus-Christ Gmbh, 3360 Osterode | Read-off device for determining the packed cell volume of blood |
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| US5279150A (en) * | 1992-03-13 | 1994-01-18 | Katzer Albert E | Automated miniature centrifuge |
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2004
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Patent Citations (9)
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|---|---|---|---|---|
| DE3342428A1 (en) * | 1983-11-24 | 1985-06-05 | Heraeus-Christ Gmbh, 3360 Osterode | Read-off device for determining the packed cell volume of blood |
| CN2035481U (en) * | 1988-09-24 | 1989-04-05 | 北京医疗器械研究所 | Testin device for red cell specific volume |
| JPH0643158A (en) * | 1991-04-26 | 1994-02-18 | Mochida Pharmaceut Co Ltd | Blood component measuring device |
| US5279150A (en) * | 1992-03-13 | 1994-01-18 | Katzer Albert E | Automated miniature centrifuge |
| CN1128066A (en) * | 1993-07-02 | 1996-07-31 | 美国3M公司 | Integrated optical coupler |
| CN2437071Y (en) * | 2000-06-14 | 2001-06-27 | 徐仁荣 | Brushless dc motor |
| JP2002323479A (en) * | 2001-04-24 | 2002-11-08 | Teruaki Ito | Blood serum and blood clot separation-face deciding apparatus |
| CN1393986A (en) * | 2001-06-29 | 2003-01-29 | 黄艳 | Combined power supply |
| CN2699285Y (en) * | 2004-05-25 | 2005-05-11 | 刘进 | Centrifugal type blood composition specific volume measurement equipment |
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| Title |
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| WS/T 123-1999 红细胞比积的测定. 丛玉隆，邓新立,1-3,中华人民共和国卫生部. 1999 现代医学实验方法. 汪谦，1167-1172，人民卫生出版社. 1997 |
| WS/T 123-1999 红细胞比积的测定. 丛玉隆，邓新立,1-3,中华人民共和国卫生部. 1999 * |
| 现代医学实验方法. 汪谦，1167-1172，人民卫生出版社. 1997 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109932284A (en) * | 2019-03-15 | 2019-06-25 | 上海市嘉定区中心医院 | A kind of hemorheology batch detector methods of optimization |
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|---|---|
| CN1584546A (en) | 2005-02-23 |
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