CN100399913C - Biological activity milk and process for preparing same - Google Patents
Biological activity milk and process for preparing same Download PDFInfo
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- CN100399913C CN100399913C CNB031112897A CN03111289A CN100399913C CN 100399913 C CN100399913 C CN 100399913C CN B031112897 A CNB031112897 A CN B031112897A CN 03111289 A CN03111289 A CN 03111289A CN 100399913 C CN100399913 C CN 100399913C
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Abstract
The present invention discloses bioactive milk. Bioactive ingredients extracted from animal viscera can be added into raw milk to prepare powdered milk or fresh milk. The preparation method of bioactive extract liquor comprises: removing impurities, such as muscle, membrane, etc. from animal viscera; adding water and homogenating for standing; freezing the liquor at a temperature of-25 DEG C for 48 hours; taking the liquor out for melting in water bath at a temperature of 37 DEG C; repeating the processes for three times; then, heating melted homogenate liquor in water bath to 85 DEG C and preserving heat for 30 minutes; cooling the homogenate liquor for 2 hours; centrifugating the homogenate liquor and fetching supernatant liquor; ultra filtering the supernatant liquor at 6000 dalton to remove macromolecules and hybrid proteins to obtain the bioactive ingredient extract liquor. In the present invention, powdered milk or fresh milk contains various bioactive ingredients needed by a human body, such as amino acid, polypeptides, immunoglobulins, various kind so phosphatide, vitamins, transfer factors, lipopolysaccharide, purines, etc.; the bioactive ingredients are favorable to the absorption by a human body and has the advantages of regulating the physiological function of a human body, enhancing immunity, delaying aging and effectively preventing and relieving diseases relevant to the liver, stomach and kidney, cardio-cerebrovascular disease, etc.; the present invention also has good health care effect.
Description
Technical field
The present invention relates to a kind of biologically active milk and preparation method thereof.
Background technology
Milk powder and fresh milk that existing market is sold are of a great variety, no matter that a kind of milk powder and fresh milk all show as composition roughly the same, although the milk powder that class is high has also just added vegetable oil, calcium hydroxide, Dicalcium Phosphate, carrotene, the nucleotides ovum, phosphatide, mineral matter etc., or various vitamins such as vitamin A, C, D, E, B1, B2 etc., though manufacturer has taked some technical measures, in making, milk powder adds synthesized element, whether can there be the problem that can be absorbed fully by human body, and the biological activity that lacks in the breast milk to be contained, so in edible, be difficult to reach health-care effect.
Summary of the invention
The object of the present invention is to provide a kind of biologically active milk, make its nutrition help absorption of human body, and have health care.
Biologically active of the present invention milk is to be primary raw material with milk or goat milk, with biologically active effective ingredient science compatibility, take modern biological high-tech extraction process, from the organs such as the animal heart, brain, thymus gland, liver, spleen, stomach, kidney, cartilage, embryo, placental blood such as qualified pig, horse, ox, sheep of quarantining, extract multiple biological activities such as amino acid, polypeptide, immunoglobulin (Ig), phosphatide, transfer factor, purine, calcium activated, be mixed with biologically active milk with health care.
The preparation method of biologically active milk of the present invention is:
1, the extraction of biological activity
The animal organ is removed impurity such as muscle, film, acceptable material, add 1 times of water homogenate and place-25 ℃ after freezing 48 hours, take out in 37 ℃ of water-baths and melt, three times so repeatedly, homogenate water-bath after will melting then is heated to 85 ℃ of insulations 30 minutes, and placed after 2 hours at cold place, with 4000 rev/mins speed centrifugal 30 minutes, temperature is got supernatant for 4 ℃, less than 6000 dalton's ultrafiltration, remove big molecule and foreign protein through molecular weight, it is standby to get the biological activity extract.Measure biological activity content such as polypeptide, amino acid, immunoglobulin (Ig), purine with instrument precisions such as spectrophotometer, liquid chromatograies.
2, the allotment of biologically active milk powder
Raw milk is checked and accepted, and clean breast adds the biological activity extract of raw milk weight 0.3～0.9%, fat corrected milk(FCM) carries out sterilization, vacuum such as concentrates at conventional method preparation cost invention biologically active milk.
Raw milk of the present invention can be formulated into full-cream or degreasing biologically active milk powder or biologically active fresh milk by the standardization allotment.
Its concocting method is: raw milk is checked and accepted, clean breast, press whole milk standardization allotment: fatty 20～24%, and protein 21～28%, lactose 30%, mineral matter 3.5%, sucrose 16～19%, moisture content 2.5% adds the biological activity extract of clean newborn weight 0.3～0.9% again, through 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, and it is former 1/4th that newborn volume is reduced to, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active whole milk powder of the present invention.
Raw milk is checked and accepted, clean breast, press the skimmed milk standardization and allocate: protein 45～50%, lactose 25～30%, mineral matter 3.5%, sucrose 16～19%, moisture content 2.5%, the biological activity extract that adds clean newborn weight 0.3～0.9% again, 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, the breast volume is reduced to former 1/4th, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active skimmed milk power of the present invention.
The fresh milk allotment is pressed in raw milk examination, clean breast, standardization, adds clean newborn weight 0.3～0.9% biological activity extract, gets fat corrected milk(FCM) and carries out 135 ℃ of ultra high temperature sterilizations, and cooling, aseptic canning, warehouse-in get biologically active fresh milk of the present invention.
Through check, contain 50 milligrams of polypeptide, 24 milligrams in amino acid, 9 milligrams of multiclass phosphatidase 11s, 5 milligrams of immunoglobulin (Ig)s, 5 milligrams in purine, 10 milligrams of transfer factor, 10 milligrams of calcium activateds in the 100 grams biologically active milk of the present invention.
Biologically active extract of the present invention is taked to freeze for three times molten, hydrolysis, and molecular weight is less than 6000 dalton's ultrafiltration, and decompression concentrates, and improves content, reduces abiotic active ingredient, reduces to produce to consume, and improves the quality of products; The raw material difference that extract is used: the used raw material of the present invention is the organs such as heart and brain, thymus gland, liver, spleen, stomach, kidney, cartilage, embryo, placental blood of comprehensive utilization animal; The present invention has added biological activity in milk powder and fresh milk, make multiple biological activities such as the amino acid that contains needed by human body in milk powder and the fresh milk, polypeptide, immunoglobulin (Ig), multiclass phosphatide, vitamin, transfer factor, lipopolysaccharides, purine and help absorption of human body.Experimental results show that through the consumer, this biologically active effective ingredient can be reconciled the physiological function of human body, strengthen immunity, delay senility, can effectively prevent and alleviate the generation of illnesss such as liver, stomach, kidney and cardiovascular and cerebrovascular again, drink the effect that 50 gram biologically active milk powder are equivalent to take five or five similar capsule health-care product of content 0.5 gram.
Biologically active effective ingredient function is:
Thymic extract: this active ingredient content of peptides can reach more than the 14mg/ml, and amino acid is formed 15 kinds, the stem cell that marrow provided can be changed into the T cell, strengthens immunity, the viral infection resisting effect is remarkable;
The liver cell extract: this active ingredient content of peptides can reach more than the 25mg/ml, and amino acid is formed 17 kinds, can promote hepatocellular DNA synthetic, and various hepatopathys are had obvious treatment and prevention effect;
Bone extract: this work generates part and contains 18 seed amino acids, contains class bone metabolic factor, and calcium activated has facilitation for calcium deficiency, rheumatism, union;
Stomach extract: this active ingredient mucoprotein content can be resisted pepsic digestion and absorption hydrochloric acid in gastric juice more than 85%, and gastric and duodenal ulcer focus face is played physiological protection and lubrication;
Spleen extract, this active ingredient content of peptides can reach more than the 4mg/ml, and 8 kinds of institute's amino acid/11s, ribose are greater than 100mg/ml, and be powerful for viral infection and autoimmune disease;
Multiclass phosphatide: PC content is used for neurasthenia, local hemostasis, atherosclerotic, softening blood vessel, enhancing memory greater than 56.5%;
Embryo, placental blood extract: more than the biological activity content of peptides 16mg/ml, immunoglobulin (Ig) all has good effect greater than 20mg/ml for slow aging, immunological regulation and various sick head;
Animal heart extract: content of peptides more than the hypoxanthine 0.25mg/ml, can improve the activity of coacetylase greater than 2mg/ml, to promoting organism metabolism, muscular atrophy, leucocyte and decrease of platelet, hepatopathy, heart disease remarkable treatment function is arranged;
Brain extract: more than this active ingredient content of peptides 10mg/ml, contain 18 seed amino acids, fine effect is arranged for cerebrovascular disease and cerebral arteriovenous malformation cerebral agenesis etc.
The specific embodiment
Example one: raw milk is checked and accepted, clean breast, press whole milk standardization allotment: fatty 24%, and protein 21%, lactose 30%, mineral matter 3.5%, sucrose 19%, moisture content 2.5% adds the biological activity extract of clean newborn weight 0.3% again, through 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, and it is former 1/4th that newborn volume is reduced to, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active whole milk powder of the present invention.
Example two: raw milk is checked and accepted, clean breast, press whole milk standardization allotment: fatty 24%, and protein 24%, lactose 30%, mineral matter 3.5%, sucrose 16%, moisture content 2.5% adds the biological activity extract of clean newborn weight 0.6% again, through 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, and it is former 1/4th that newborn volume is reduced to, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active whole milk powder of the present invention.
Example three: raw milk is checked and accepted, clean breast, press the skimmed milk standardization and allocate: protein 48%, lactose 27%, mineral matter 3.5%, sucrose 19%, moisture content 2.5%, the biological activity extract that adds clean newborn weight 0.9% again, 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, the breast volume is reduced to former 1/4th, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active skimmed milk power of the present invention.
Example four: raw milk examination, clean breast, standardization, press the fresh milk allotment, add clean newborn weight 0.9% biological activity extract, get fat corrected milk(FCM) and carry out 135 ℃ of ultra high temperature sterilizations, cooling, aseptic canning, warehouse-in get biologically active fresh milk of the present invention.
Claims (5)
1. a biologically active is suckled, and it is characterized in that: described biologically active milk is formulated by clean breast and biological activity extract, and wherein the biological activity extract accounts for the 0.3-0.9% of clean breast; Described biological activity extract is the animal organ to be removed impurity such as muscle, film, get acceptable material, add 1 times of water homogenate and place-25 ℃ after freezing 48 hours, take out in 37 ℃ of water-baths and melt three times so repeatedly, homogenate water-bath after will melting then is heated to 85 ℃ of insulations 30 minutes, cooled off 2 hours, supernatant is got in centrifugation, through 6000 dalton's ultrafiltration, remove big molecule and foreign protein, make.
2. the preparation method of biologically active milk is characterized in that:
(1) animal organ is removed impurity such as muscle, film, get acceptable material, add 1 times of water homogenate and place-25 ℃ after freezing 48 hours, take out in 37 ℃ of water-baths and melt three times so repeatedly, homogenate water-bath after will melting then is heated to 85 ℃ of insulations 30 minutes, cooled off 2 hours, supernatant is got in centrifugation, through 6000 dalton's ultrafiltration, remove big molecule and foreign protein, get the biological activity extract;
(2) raw milk is checked and accepted, clean breast adds the biological activity extract of raw milk weight 0.3-0.9%, fat corrected milk(FCM) carries out sterilization, vacuum such as concentrates at conventional method preparation cost invention biologically active milk.
3. the preparation method of biologically active milk according to claim 2, it is characterized in that: raw milk is checked and accepted, clean breast, press whole milk standardization allotment: fatty 24%, protein 21-24%, lactose 30%, mineral matter 3.5%, sucrose 16-19%, moisture content 2.5%, the biological activity extract that adds clean newborn weight 0.3-0.9% again, through 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, the breast volume is reduced to former 1/4th, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active whole milk powder of the present invention.
4. the preparation method of biologically active milk according to claim 2, it is characterized in that: raw milk is checked and accepted, clean breast, press the skimmed milk standardization and allocate: protein 48%, lactose 27%, mineral matter 3.5%, sucrose 19%, moisture content 2.5%, the biological activity extract that adds clean newborn weight 0.3-0.9% again, 86 ℃ of sterilizations, 15s, vacuum concentrates 55 ℃ of boiling points, and it is former 1/4th that newborn volume is reduced to, 60 ℃ of spray-dryings, cooling, check, packing, warehouse-in get biologically active skimmed milk power of the present invention.
5. the preparation method of biologically active milk according to claim 2, it is characterized in that: raw milk is checked and accepted, clean newborn, standardization, press the fresh milk allotment, the biological activity extract that adds clean newborn weight 0.3-0.9%, get fat corrected milk(FCM) and carry out 135 ℃ of ultra high temperature sterilizations, cooling, aseptic canning, warehouse-in get biologically active fresh milk of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031112897A CN100399913C (en) | 2003-03-25 | 2003-03-25 | Biological activity milk and process for preparing same |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031112897A CN100399913C (en) | 2003-03-25 | 2003-03-25 | Biological activity milk and process for preparing same |
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| Publication Number | Publication Date |
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| CN1839700A CN1839700A (en) | 2006-10-04 |
| CN100399913C true CN100399913C (en) | 2008-07-09 |
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| CNB031112897A Expired - Fee Related CN100399913C (en) | 2003-03-25 | 2003-03-25 | Biological activity milk and process for preparing same |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101167494B (en) * | 2007-12-03 | 2012-01-25 | 山东银香大地乳业有限公司 | Milk containing brain polypeptide extraction and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360833A (en) * | 2000-12-29 | 2002-07-31 | 中国农业大学 | Prepn for earthworm antibacterial peptide |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360833A (en) * | 2000-12-29 | 2002-07-31 | 中国农业大学 | Prepn for earthworm antibacterial peptide |
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