CN100392543C - Full-automatic biochemistry instrument heated culture automatic temperature control equipment and temperature control method - Google Patents
Full-automatic biochemistry instrument heated culture automatic temperature control equipment and temperature control method Download PDFInfo
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- CN100392543C CN100392543C CNB2004101028814A CN200410102881A CN100392543C CN 100392543 C CN100392543 C CN 100392543C CN B2004101028814 A CNB2004101028814 A CN B2004101028814A CN 200410102881 A CN200410102881 A CN 200410102881A CN 100392543 C CN100392543 C CN 100392543C
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Abstract
The present invention provides an incubation temperature automatic controller and a temperature control method of a full automatic biochemical instrument. The present invention comprises: a digital temperature sensor directly connected with a single chip computer; multiple-point temperature measurement; a self-setting proportional integral controller. A control signal is outputted by a digital-to-analog circuit to control the pulse width outputted by a pulse width modulation circuit and finally control the output heating power. A temperature automatic controller comprises a digital temperature measuring circuit, a single chip computer circuit, the digital-to-analog circuit, the pulse width modulation circuit, a power amplification circuit, a Buck converter circuit and a serial port chip. The present invention realizes temperature setting and display on a supervisory computer by the communication of the supervisory computer and the single chip computer. The present invention has the advantages of accurate temperature control, high precision and high anti-interference capability. The present invention can eliminate hysteresis and environment temperature disturbance.
Description
Technical field
The invention belongs to biochemical instruments temperature control technology field, a kind of full-automatic biochemistry instrument heated culture automatic temperature control equipment and control method particularly are provided, be applicable to the incubation digital temperature control of the full automatic biochemical apparatus of big molecular immune reaction.
Technical background
When the antigen of mark carries out immune response at synantibody, need accurately control temperature of reaction, the accuracy that the variation of temperature antagonist is measured has very big influence, therefore need accurately control the mechanical carrier temperature of incubation reaction and the environment temperature of reaction.
The incubation reaction of full automatic biochemical apparatus is carried out on the machine carousel of rotating.Machine carousel is divided fixing and rotation two parts.The test tube that reactant is housed is placed on the rotating part of rotating disk.Heating arrangement is placed on the fixed part of rotating disk.Form an airtight relatively cavity between fixed part and the rotating part.Reactant places in the cavity in the bottom of test tube.Heating arrangement is regulated cavity temperature by the Heating rotary-disc fixed part.
The variation of the rotation of rotating disk and sealing, environment temperature has very big influence to the temperature in the cavity.That this controlled device has is non-linear, time lag, the time characteristics that become, adopt conventional proportional integral adjustment control can not reach excellent control effect, adopt the temperature survey of single-point can not accurately reflect the environment temperature at reactant place.
Summary of the invention
The object of the present invention is to provide a kind of full-automatic biochemistry instrument heated culture automatic temperature control equipment and control method, the cavity temperature at control reactant place overcomes dial rotation and environmental change to the cavity Temperature Influence at a certain set-point.It has the temperature control precision height, good reliability, the characteristics that antijamming capability is strong.
Full-automatic biochemistry instrument heated culture automatic temperature control equipment of the present invention is by single chip circuit, pulse-width modulation circuit, and power amplification circuit, digital temperature measurement circuit, the Buck converter circuit, the upper machine communication circuit, D/A converting circuit, scm software etc. are partly formed.
1) Automatic Temperature Control is realized by serial communication interface with the communication of host computer.
2) pulse-width modulation circuit is that core realizes with the pulse width modulating chip, and has current feedback.It is given to be voltage signal, exports direct driving power amplifying circuit, and obtains stable electric current behind the flat ripple of Buck converter circuit, is used for heating the Electric radiant Heating Film silk.
3) single chip circuit connects with D/A converting circuit by bus.D/A converting circuit output voltage signal control pulse-width modulation circuit.
4) digital temperature measurement circuit is directly to be connected with the controller general input/output port, and single-chip microcomputer reads temperature value by the sequential of appointment.
5) management of Automatic Temperature Control and control function are to be realized by the software in the single-chip microcomputer.This software comprises a kind of temperature-controlled process.
The present invention adopts full-automatic biochemistry instrument heated culture automatic temperature control equipment to carry out temperature controlled method to comprise:
1) by digital temperature sensor controlled device is carried out temperature survey, and be converted to temperature value, temperature is read by single-chip microcomputer.
2) adopt multipoint temperature measuring, measure the temperature of rotating disk fixed part, the environment temperature in the cavity and the environment temperature in the biochemical instruments respectively.
3) temperature sensor of band serial digital output is adopted in temperature survey, can directly link to each other with microprocessor, has omitted the design of analog to digital conversion circuit, has improved measuring accuracy and reliability.
4) in obtaining rotating disk fixed part temperature, cavity in temperature and the biochemical instruments after the environment temperature, by 2 temperature variation curve in the chamber, calculate the time-delay of temperature control object, and according to different environment temperatures, be adjusted in the regulator parameter under the varying environment, and feedforward compensation is carried out in adjusting.
Characteristics of the present invention and effect
The present invention adopts digital temperature sensor, utilizes single-chip microcomputer that data are handled, and result of calculation converts voltage signal to by D/A converting circuit.This voltage signal is controlled the pulse width that pulse-width modulation circuit is exported as the input of pulse-width modulation circuit, and pulse width is the time of field effect transistor conducting, thus the output power of control heating Electric radiant Heating Film silk.The method that this Automatic Temperature Control adopts multi-point temp to detect, and the proportional integral adjusting of adopting feedforward on this basis and adjusting certainly can overcome dial rotation and environmental change effectively to Temperature Influence, reach high control precision.
The invention has the advantages that: the temperature control precision height; Antijamming capability is strong; Can eliminate the influence of time lag.
Description of drawings
The coupled schematic representation of apparatus of Fig. 1 Automatic Temperature Control of the present invention.Wherein, rotating part 1, the fixed part 2 of machine carousel, mechanical rotating shaft 3, Electric radiant Heating Film silk 4, test tube 5, the digital temperature sensor 6 of the circular machine carousel of aluminum.
Fig. 2 temperature-control circuit structural drawing of the present invention.Wherein, upper machine communication circuit 7, digital temperature measurement circuit 13, electric heating mould silk 4, single chip circuit 8, D/A converting circuit 9, pulse-width modulation circuit 10, power amplification circuit 11, Buck converter circuit 12.
Fig. 3 temperature control of the present invention realization flow block diagram.
Embodiment
The accompanying drawing and the enforcement of digital temperature control system of the present invention are described in detail as follows:
The enforcement of digital temperature control system of the present invention: the coupled device of Automatic Temperature Control comprises as shown in Figure 1: the rotating part 1 of the circular machine carousel of aluminum and the mechanical rotating shaft 3 that is attached thereto, the fixed part 2 of machine carousel.Be placed with 60 identical test tubes 5 above the machine carousel rotating part 1, divide two rows to be uniformly distributed on the rotating disk rotating part 1.Reaction cartridge thing in the test tube.Electric radiant Heating Film silk 4 is positioned in the middle of the machine carousel fixed part.Digital temperature sensor 6 is installed in respectively in the fixed part, cavity of machine carousel and in the biochemical instruments.Host computer links to each other with Automatic Temperature Control by serial communication interface.Automatic Temperature Control links to each other with digital temperature sensor 6 with Electric radiant Heating Film silk 4 on the machine carousel by cable.
Automatic Temperature Control of the present invention is specifically implemented: structure comprises single chip circuit 8 and the digital temperature measurement circuit 13 that is attached thereto as shown in Figure 2.Single-chip microcomputer and digital temperature sensor are realized reading of temperature by the mode of serial communication.D/A converting circuit 9 and the pulse-width modulation circuit 10 that is attached thereto, pulse-width modulation circuit is exported direct power controlling amplifying circuit 11, and the output of power amplification circuit connects Buck converter circuit 12 and carries out flat ripple, and the electric current of output, voltage are stablized.
The present invention also comprises the communicating circuit 2 that links to each other with single-chip microcomputer.
Principle of work of the present invention: single-chip microcomputer is communicated by letter by serial mode with digital temperature sensor, sends order by single-chip microcomputer to digital temperature sensor and reads temperature.Digital temperature sensor is measured temperature automatically, and is converted to temperature value, sends single-chip microcomputer to.Single-chip microcomputer by D/A converting circuit, becomes controlled quentity controlled variable into voltage signal by data processing, the control pulse-width modulation circuit, and the width of regulating impulse, thus regulate the make-and-break time of field effect transistor in the one-period.The Buck converter circuit plays flat ripple, and output is become constant current value.For example when measured temperature is too high,, pulse width is diminished by changing the output voltage values of D/A converting circuit, thereby the electric current that is added on the pyroelectric film silk is reduced, output power is reduced,, make heating and heat radiation reach thermal equilibrium at the design temperature place by regulating repeatedly.Control algolithm adopts from the proportional integral of adjusting and regulates and feedforward compensation, by the temperature survey of multiple spot, calculates heat conducting time-delay, by the measurement of environment temperature, calculate the model of cooling procedure, thereby overcome the controlled device time lag, the time problem such as change, improved control accuracy.
The software flow of temperature-controlled process of the present invention may further comprise the steps as shown in Figure 3:
1) carries out temperature survey by digital temperature sensor earlier, and temperature is passed to single-chip microcomputer.
2) temperature value and the set-point of Automatic Temperature Control by recording, after by the control computing, the output control signal corresponding.
3) Shu Chu control signal converts analog voltage to through D/A converting circuit, and the magnitude of voltage of output is regulated the pulse width of pulse-width modulation circuit output.
4) heating power of Electric radiant Heating Film silk is regulated in the change by pulse width.
Claims (2)
1. full-automatic biochemistry instrument heated culture automatic temperature control equipment is characterized in that: by single chip circuit, and pulse-width modulation circuit, power amplification circuit, digital temperature measurement circuit, Buck converter circuit, the upper machine communication circuit, D/A converting circuit, scm software is formed;
A, controller are realized by serial communication interface with the communication of host computer;
B, pulse-width modulation circuit are that core realizes with the pulse width modulating chip, and have current feedback, and it is given to be voltage signal, exports direct driving power amplifying circuit, and obtains stable electric current behind the flat ripple of Buck converter circuit, is used for heating the Electric radiant Heating Film silk;
C, single chip circuit connect with D/A converting circuit by bus, D/A converting circuit output voltage signal control pulse-width modulation circuit;
D, temperature measurement circuit are directly to be connected with the controller general input/output port, and single-chip microcomputer reads temperature value by the sequential of appointment; The management of controller and control function are to realize that by the software in the single-chip microcomputer this software comprises a kind of temperature-controlled process.
2. one kind is adopted the described self-actuated controller thermometric of claim 1 to carry out temperature controlled method, and it is characterized in that: this method comprises:
A, controlled device is carried out temperature survey, and be converted to temperature value, temperature is read by single-chip microcomputer by digital temperature sensor;
B, employing multipoint temperature measuring are measured the temperature of rotating disk fixed part, the environment temperature in the cavity and the environment temperature in the biochemical instruments respectively;
The temperature sensor of band serial digital output is adopted in c, temperature survey, directly links to each other with single-chip microcomputer, has omitted the design of analog to digital conversion circuit, has improved measuring accuracy and reliability;
D, in obtaining rotating disk fixed part temperature, cavity in temperature and the biochemical instruments after the environment temperature, by 2 temperature variation curve in the chamber, calculate the time-delay of temperature control object, and according to different environment temperatures, be adjusted in the regulator parameter under the varying environment, and feedforward compensation is carried out in adjusting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004101028814A CN100392543C (en) | 2004-12-29 | 2004-12-29 | Full-automatic biochemistry instrument heated culture automatic temperature control equipment and temperature control method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004101028814A CN100392543C (en) | 2004-12-29 | 2004-12-29 | Full-automatic biochemistry instrument heated culture automatic temperature control equipment and temperature control method |
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| Publication Number | Publication Date |
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| CN1621987A CN1621987A (en) | 2005-06-01 |
| CN100392543C true CN100392543C (en) | 2008-06-04 |
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| CNB2004101028814A Expired - Fee Related CN100392543C (en) | 2004-12-29 | 2004-12-29 | Full-automatic biochemistry instrument heated culture automatic temperature control equipment and temperature control method |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1986012B (en) * | 2005-12-19 | 2011-01-12 | 陈虎 | Thermostatic medical fluid heating system |
| CN102280348A (en) * | 2010-06-08 | 2011-12-14 | 江苏天瑞仪器股份有限公司 | Electron impact ion source control system |
| CN102109861B (en) * | 2010-12-15 | 2013-04-10 | 复旦大学 | High-frequency PWM (pulse width modulation) temperature control device and control method for thermal analyzer |
| AU2013202793B2 (en) * | 2012-07-31 | 2014-09-18 | Gen-Probe Incorporated | System, method and apparatus for automated incubation |
| CN116124833A (en) * | 2022-11-30 | 2023-05-16 | 国网江苏省电力有限公司南通供电分公司 | Temperature-controllable electric ignition device and flash point tester with same |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2511047Y (en) * | 2001-12-20 | 2002-09-11 | 华中科技大学 | Microcomputer temperature-compensated crystal oscillator |
| CN1492551A (en) * | 2003-09-30 | 2004-04-28 | 清华大学 | Digital intelligent temperature control method and temperature control semiconductor laser |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2511047Y (en) * | 2001-12-20 | 2002-09-11 | 华中科技大学 | Microcomputer temperature-compensated crystal oscillator |
| CN1492551A (en) * | 2003-09-30 | 2004-04-28 | 清华大学 | Digital intelligent temperature control method and temperature control semiconductor laser |
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