CN100353957C - Chinese medicinal herb composition for treating rheumatism - Google Patents
Chinese medicinal herb composition for treating rheumatism Download PDFInfo
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- CN100353957C CN100353957C CNB031304273A CN03130427A CN100353957C CN 100353957 C CN100353957 C CN 100353957C CN B031304273 A CNB031304273 A CN B031304273A CN 03130427 A CN03130427 A CN 03130427A CN 100353957 C CN100353957 C CN 100353957C
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Abstract
The present invention discloses a traditional Chinese medicine compound for treating rheumatism, which is composed of the following components: 10 to 20 wt% of codonopsis pilosula, 8 to 20 wt% of danshen root, 10 to 20 wt% of largehead atractylodes rhizome, 8 to 20 wt% of indian bread, 6 to 20 wt% of notoginseng, 10 to 30 wt% of hemlock parsley, 2 to 10 wt% of curare powder, 5 to 15 wt% of twotoothed achyranthes root and 5 to 20 wt% of liquorice. The clinical practice proves that the present invention has the functions of benefiting qi, nourishing blood, promoting blood circulation for removing obstruction in collaterals, expelling rheumatism and relieving pain. The present invention mainly treats deficiency of qi and blood, rheumatism, blood stasis, muscle and joint sour pain, arthrocele, stiffness deformation of joints or muscular atrophy, short breath, weakness, rheumatoid arthritis, lumbar muscle strain, soft tissue contusion, etc., and has the advantages of reasonable prescription, manifestation and root cause of disease treatment, good analgesic effect, less side effect, etc., and the effective rate of treatment is 91.1%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of arthromyodynia.
Background technology
At present, some arthromyodynias as: human beings'health in serious threats such as rheumatism, rheumatoid arthritis, arthralgia, arthroncus, joint deformity, ankylosis, person in middle and old age's lumbago and skelalgia, numb limbs and tense tendons, hyperosteogeny, cervical vertebra pain, scapulohumeral periarthritis, soft tissue injury and lumbar muscle strain, the lighter influences the quality of work, life, weight person hinders patient's action, even the patient be can't take care of oneself.At present, the medicine of more existing treatment arthromyodynias is being sold on the market, as: WANGBI CHONGJI, SUANTONG LING, Chinese rheumatism tablet etc.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of arthromyodynia, in order to alleviate the arthromyodynia subject discomfort.
Technical scheme of the present invention is summarized as follows:
The Chinese medicine composition of treatment arthromyodynia is made of following component by weight percentage: Radix Codonopsis 10～20%, Radix Salviae Miltiorrhizae 8～20%, the Rhizoma Atractylodis Macrocephalae 10～20%, Poria 8～20%, Radix Notoginseng 6～20%, Rhizoma Chuanxiong 10～30%, Semen Strychni modulation powder 2～10%, Radix Achyranthis Bidentatae 5～15%, Radix Glycyrrhizae 5～20%.
In said components Radix Codonopsis preferably 12～18%, Radix Salviae Miltiorrhizae preferably 10～18%, the Rhizoma Atractylodis Macrocephalae preferably 12～18%, Poria preferably 10～18%, Radix Notoginseng preferably 10～18%, Rhizoma Chuanxiong preferably 12～25%, Semen Strychni modulation powder preferably 4～8%, Radix Achyranthis Bidentatae preferably 7～13%, Radix Glycyrrhizae preferably 7～18%.
In said components, can also add Pheretima 0～10%.
In said components, can also add Radix Saposhnikoviae 0～10%.
In said components, can also add Semen Coicis 0～10%.
In said components, can also add Rhizoma Et Radix Notopterygii 0～10%.
In said components, can also add Radix Angelicae Pubescentis 0～10%.
In the mentioned component, palpitation due to deficiency of blood etc. is controlled in the invigorating the spleen and replenishing QI of Radix Codonopsis energy; Radix Salviae Miltiorrhizae has the effect of blood circulation promoting and blood stasis dispelling; The Rhizoma Atractylodis Macrocephalae dispel the wind cold-damp numbness, spleen invigorating granulation promoting are improved the muscle arteries and veins and are relaxed; The Radix Notoginseng slightly warm in nature, clots absorbing hemostasis, subduing swelling and relieving pain; The Semen Strychni blood stasis dispelling disappears bitterly, removes hemiplegia numbness etc.
The present invention is pure Chinese medicine composition, Clinical Practice proves, it has the function of benefiting QI and nourishing blood, promoting blood circulation to remove obstruction in the collateral, wind-expelling pain-stopping, cures mainly insufficiency of vital energy and blood, the resistance of the rheumatism stasis of blood, muscle joint aches, arthroncus, stiffness and deforming or amyotrophy, shortness of breath and fatigue, rheumatism and rheumatoid arthritis, lumbar muscle strain, soft tissue contusion etc.The present invention has reasonable recipe, treating both the principal and secondary aspects of a disease, and advantage such as analgesic effect is good, and side effect is little, and raw material obtains easily, and cost is lower, its treatment effective percentage is 91.1%.
The specific embodiment
The invention will be further described below in conjunction with embodiment, pharmacological experiment, toxicological experiment, clinical observation:
1. table 1 provides 16 embodiment, and unit is gram.
Table 1:
Each embodiment is prepared by the Chinese medicine manufacturing process, adopts following operation usually:
(1) medical material pre-treatment;
(2) extract;
(3) pulverize;
(4) manufacture preparation.
The present invention can make various Chinese medicine preparation: as capsule, tablet, drop pill, powder, syrup, medicated wine, mixture, pill etc.
2. pharmacology test:
(1) anti-inflammation detumescence test
With rat hindlimb, toes subcutaneous injection 10% Ovum Gallus domesticus album causes toes swelling, and observing the present invention influences the swelling degree.
(seeing Table 2)
Table 2:
The result shows: the present invention has obvious inhibitory action (P＜0.01) to toes swelling due to the rat Ovum Gallus domesticus album
(2) analgesic test
The acetic acid twisting method
Get the mice group administration, 30min after the continuous ig7d last administration, ip in mice 0.6% acetic acid 0.2ml writes down in each Mus writhing response time of origin and the 15min and turns round the body number of times, and calculates and turn round the body incidence rate.(seeing Table 3)
Table 3:
Compare with matched group
*P＜0.001
*P＜0.01
By table 3 as seen, capsule of the present invention all can obviously prolong in the high and low dose group turns round the body time of origin, reduces the number of times that writhing response takes place.
3. toxicology test:
(1) acute toxicity test:
100 times of adult's dosage on probation do not cause any toxic reaction of experimental animal, median lethal dose(LD 50) (LD
50Be the 4053.22mg/kg body weight).
(2) long term toxicity test:
Observed three months, any toxic reaction does not all take place in the high and low dose group.
Proof: capsule dosage of the present invention is safe and reliable.
4. clinical trial is observed:
Table 4 is diagnosis of doctor trained in Western medicine pain and effect observation;
Table 5 is traditional Chinese medical science arthromyodynia typing and effect observation;
Table 6 is medicine time and effect observation.
Table 4:
Table 5:
Table 6:
In table 4, table 5, the table 6 202 routine arthromyodynia patients are carried out clinical observation, to the pain of tissues such as the joint due to the common various diseases of doctor trained in Western medicine, skin, muscles and bones.91 examples of produce effects account for 45%; Effective 93 examples account for 46.1%; 18 invalid examples account for 8.9%.All types of arthromyodynias to traditional Chinese medical science classification also have different curative effects, wherein remarkable to the clinical effectiveness of damp-heat type and blood stasis type, obvious effective rate reaches 54%, 60.7% respectively, secondly, clinical effectiveness to raw type and rheumatism type arthromyodynia is also more obvious, obvious effective rate is respectively 41.1% and 41.7%, and is also effective to the arthromyodynia of deficiency.From medicine time, taking medicine to make effective percentage reach 91% more than the Ninth Heaven, and clinical observation shows that beneficial effect of the present invention is remarkable.
Claims (7)
1. the Chinese medicine composition of treatment arthromyodynia is characterized in that being made by following bulk drugs by weight percentage: Radix Codonopsis 10～20%, Radix Salviae Miltiorrhizae 8～20%, the Rhizoma Atractylodis Macrocephalae 10～20%, Poria 8～20%, Radix Notoginseng 6～20%, Rhizoma Chuanxiong 10～30%, Semen Strychni modulation powder 2～10%, Radix Achyranthis Bidentatae 5～15%, Radix Glycyrrhizae 5～20%.
2. the Chinese medicine composition of treatment arthromyodynia according to claim 1, it is characterized in that described components contents is Radix Codonopsis 12～18%, Radix Salviae Miltiorrhizae 10～18%, the Rhizoma Atractylodis Macrocephalae 12～18%, Poria 10～18%, Radix Notoginseng 10～18%, Rhizoma Chuanxiong 12～25%, Semen Strychni modulation powder 4～8%, Radix Achyranthis Bidentatae 7～13%, Radix Glycyrrhizae 7～18%.
3. the Chinese medicine composition of treatment arthromyodynia according to claim 1 is characterized in that, adds Pheretima 0～10% in described component.
4. the Chinese medicine composition of treatment arthromyodynia according to claim 1 is characterized in that, adds Radix Saposhnikoviae 0～10% in described component.
5. the Chinese medicine composition of treatment arthromyodynia according to claim 1 is characterized in that, adds Semen Coicis 0～10% in described component.
6. the Chinese medicine composition of treatment arthromyodynia according to claim 1 is characterized in that, adds Rhizoma Et Radix Notopterygii 0～10% in described component.
7. the Chinese medicine composition of treatment arthromyodynia according to claim 1 is characterized in that, adds Radix Angelicae Pubescentis 0～10% in described component.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031304273A CN100353957C (en) | 2003-07-21 | 2003-07-21 | Chinese medicinal herb composition for treating rheumatism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031304273A CN100353957C (en) | 2003-07-21 | 2003-07-21 | Chinese medicinal herb composition for treating rheumatism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1569053A CN1569053A (en) | 2005-01-26 |
| CN100353957C true CN100353957C (en) | 2007-12-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031304273A Expired - Lifetime CN100353957C (en) | 2003-07-21 | 2003-07-21 | Chinese medicinal herb composition for treating rheumatism |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204562B (en) * | 2006-12-19 | 2010-11-10 | 吴鹏 | External drug for chronic injury, arthritis, join thydrops and pain in shoulder, neck, waist, and leg |
| CN101732413B (en) * | 2008-11-13 | 2012-08-29 | 天津达仁堂京万红药业有限公司 | Chinese medicinal composition for treating arthromyodynia and preparation method thereof |
| CN101780146B (en) * | 2009-01-19 | 2011-11-23 | 天津达仁堂京万红药业有限公司 | Quality control method of Biqi capsules |
| CN103599416B (en) * | 2013-11-19 | 2015-09-23 | 李庆丽 | A kind of pharmaceutical composition for the treatment of chronic lumbar muscle strain |
| CN104435769A (en) * | 2014-09-23 | 2015-03-25 | 李虹 | Medicinal liquor for treating rheumatoid arthritis and preparation method thereof |
| CN110974900A (en) * | 2020-01-07 | 2020-04-10 | 陈曼 | Wind-dispelling pain-relieving powder |
| CN113679818A (en) * | 2021-10-13 | 2021-11-23 | 邱衍臣 | Composition for treating gout and rheumatoid osteoarthritis and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095371A (en) * | 1992-12-17 | 1994-11-23 | 罗纳·布朗克化学公司 | Acetate that alpha-amino group replaces or their salt, and their application in makeup |
-
2003
- 2003-07-21 CN CNB031304273A patent/CN100353957C/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095371A (en) * | 1992-12-17 | 1994-11-23 | 罗纳·布朗克化学公司 | Acetate that alpha-amino group replaces or their salt, and their application in makeup |
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| CN1569053A (en) | 2005-01-26 |
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Owner name: TIANJIN DARENTANG WANHONG PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME OR ADDRESS: TIANJIN DARENTANG DAER MEDICINE CO., LTD. |
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Address after: No. 20 Daming Road, Xiqing District, Tianjin Patentee after: TIANJIN DARENTANG JINGWANHONG PHARMACEUTICAL Co.,Ltd. Address before: Tianjin Xiqing District West Cross embankment outside Jade Road Patentee before: Tianjin Darentang Daer Pharmaceutical Co.,Ltd. |
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Granted publication date: 20071212 |