CN100349596C

CN100349596C - Medicinal powder for treating asthma and cough

Info

Publication number: CN100349596C
Application number: CNB2005100891505A
Authority: CN
Inventors: 刘益斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-08-04
Filing date: 2005-08-04
Publication date: 2007-11-21
Anticipated expiration: 2025-08-04
Also published as: CN1730068A

Abstract

The present invention relates to a medicine granule for treating cough and asthma. The medicine granule is prepared by the prescriptions of ephedra, mulberry skin, toasted almond, inula flower, pinellia tuber, baical skullcap root, loquat leaf, tendrilleaf fritillary bulb, fried stiff silkorm, fried aster, white peony alba, licorice root, peach, safflower, Japanese metaplexis pericarp and clam shell and western medicine of glycyrrhizic acid, chlorpheniramine maleate, diprophylline and hydrochloric acid racanisodamine. The tendrilleaf fritillary bulb is crushed into fine powder with 100 meshes. Besides, the rest fifteen kinds of Chinese medicine are decocted for two times by adding water. For the first time, the water is added with the quantity of 10 times, the decoction is carried out for 1.5 hours, the filtration is carried out, and filtered solutions are collected. For the second time, the water is added with the quantity of 6 times, the decoction is carried out for 1 hour, the filtration is carried out, and the filtered solutions are mixed. The filtered solutions are decompressed and concentrated into paste and are sprayed and dried into fine powder, and dextrin is added and uniformly mixed with the tendrilleaf fritillary bulb fine powder, the glycyrrhizic acid, the chlorpheniramine maleate, the diprophylline and the hydrochloric acid racanisodamine. Thus, the medicine granule can be obtained through dry extrusion, granulation, split charging, package and radiation sterilization with cobalt 60.

Description

A kind of drug particles for the treatment of cough with asthma

Technical field

The present invention relates to a kind of drug particles for the treatment of cough with asthma.

Background technology

The medicament categories of treatment cough with asthma is a lot of at present, and taking medicine granule for treating is a kind of effective method of treatment chronic cough and asthma.Now, the granular preparation of many kind treatment chronic cough and asthmas is arranged on the market, but these preparations generally are applicable to the adult, and can not reach treatment and regulate diseases such as spiritlessness and weakness, coldness of the body cold extremities, chronic bronchitis; And these preparations generally all onset is slow, it is few to be suitable for disease.Utilizing ointment is a kind of method of effective treatment cough with asthma, but this series products of market is fewer, and exists onset slow, is suitable for the few deficiency of disease.

Summary of the invention

The purpose of this invention is to provide and a kind ofly can solve above-mentioned shortcoming and defect, effectively treat the drug particles of chronic cough and asthma.

The present invention is achieved through the following technical solutions: prescription relates to Herba Ephedrae, Cortex Mori, stir-baked SEMEN ARMENIACAE AMARUM, Flos Inulae, Rhizoma Pinelliae Preparata, Radix Scutellariae, Folium Eriobotryae, Bulbus Fritillariae Cirrhosae, Bombyx Batryticatus(processed), honey-fried RADIX ASTERIS, the Radix Paeoniae Alba, Radix Glycyrrhizae, Semen Persicae, Flos Carthami, sky with shell, Concha Meretricis seu Cyclinae, glycyrrhizin, chlorphenamine maleate, diprophylline, Hydrochloric acid raceanisodamine, makes drug particles of the present invention.Concrete content prescription is: be 10: 10: 8 by weight: 8: 8: 8: 6: 4: 9: 9: 6: 6: 4: 4: 10: 10 take by weighing Herba Ephedrae, Cortex Mori, stir-baked SEMEN ARMENIACAE AMARUM, Flos Inulae, Rhizoma Pinelliae Preparata, Radix Scutellariae, Folium Eriobotryae, Bulbus Fritillariae Cirrhosae, Bombyx Batryticatus(processed), honey-fried RADIX ASTERIS, the Radix Paeoniae Alba, Radix Glycyrrhizae, Semen Persicae, Flos Carthami, sky with shell, Concha Meretricis seu Cyclinae, take by weighing 10 milligrams of glycyrrhizins, 1 milligram of chlorphenamine maleate, 20 milligrams of diprophyllines, 2 milligrams of Hydrochloric acid raceanisodamines, make drug particles of the present invention.

Preparation method of the present invention is as follows: get Bulbus Fritillariae Cirrhosae by prescription, be ground into 100 order fine powders, other gets all the other 15 flavor Chinese crude drugs, decocts with water secondary, adds 10 times of amounts of water for the first time, decocts 1.5 hours, filters, and collects filtrate; For the second time add 6 times of amounts of water, decocted 1 hour, filter, merging filtrate, filtrate decompression is condensed into cream, spray drying, get fine powder, add dextrin, and with above-mentioned Bulbus Fritillariae Cirrhosae fine powder, glycyrrhizin, chlorphenamine maleate, diprophylline, Hydrochloric acid raceanisodamine mix homogeneously, do extruding and granulate, packing, packing, the co-60 radiation sterilization, promptly.

The invention has the advantages that: the cold expelling that induces sweat, removing heat-phlegm, relieving cough and asthma, can effectively treat chronic cough and asthma.

The specific embodiment

Embodiment 1, by prescription take by weighing Herba Ephedrae 100 gram, Cortex Mori 100 grams, stir-baked SEMEN ARMENIACAE AMARUM 80 grams, Flos Inulae 80 grams, Rhizoma Pinelliae Preparata 80 grams, Radix Scutellariae 80 grams, Folium Eriobotryae 60 grams, Bulbus Fritillariae Cirrhosae 40 grams, Bombyx Batryticatus(processed) 90 grams, honey-fried RADIX ASTERIS 90 grams, the Radix Paeoniae Alba 60 grams, Radix Glycyrrhizae 60 grams, Semen Persicae 40 grams, Flos Carthami 40 grams, day with shell 100 grams, Concha Meretricis seu Cyclinae 100 grams, get Bulbus Fritillariae Cirrhosae, be ground into 100 order fine powders, other gets all the other 15 flavor Chinese crude drugs, decoct with water secondary, add for the first time 10 times of amounts of water, decocted 1.5 hours, filter, collect filtrate; For the second time add 6 times of amounts of water, decocted 1 hour, filter, merging filtrate, filtrate decompression is condensed into cream, spray drying, get fine powder, add dextrin, and with above-mentioned Bulbus Fritillariae Cirrhosae fine powder, 10 milligrams of glycyrrhizins, 1 milligram of chlorphenamine maleate, 20 milligrams of diprophyllines, 2 milligrams of mix homogeneously of Hydrochloric acid raceanisodamine, do extruding and granulate, packing, packing, the co-60 radiation sterilization, promptly.

Embodiment 2, by prescription take by weighing Herba Ephedrae 333 gram, Cortex Mori 333 grams, stir-baked SEMEN ARMENIACAE AMARUM 266 grams, Flos Inulae 266 grams, Rhizoma Pinelliae Preparata 266 grams, Radix Scutellariae 266 grams, Folium Eriobotryae 200 grams, Bulbus Fritillariae Cirrhosae 133 grams, Bombyx Batryticatus(processed) 300 grams, honey-fried RADIX ASTERIS 300 grams, the Radix Paeoniae Alba 200 grams, Radix Glycyrrhizae 200 grams, Semen Persicae 133 grams, Flos Carthami 133 grams, day with shell 333 grams, Concha Meretricis seu Cyclinae 333 grams, get Bulbus Fritillariae Cirrhosae, be ground into 100 order fine powders, other gets all the other 15 flavor Chinese crude drugs, decoct with water secondary, add for the first time 10 times of amounts of water, decocted 1.5 hours, filter, collect filtrate; For the second time add 6 times of amounts of water, decocted 1 hour, filter, merging filtrate, filtrate decompression is condensed into cream, spray drying, get fine powder, add dextrin, and with above-mentioned Bulbus Fritillariae Cirrhosae fine powder, 10 milligrams of glycyrrhizins, 1 milligram of chlorphenamine maleate, 20 milligrams of diprophyllines, 2 milligrams of mix homogeneously of Hydrochloric acid raceanisodamine, do extruding and granulate, packing, packing, the co-60 radiation sterilization, promptly.

It below is concrete case

Case 1 Hu Zhongjian man occupation in 27 years old: company clerk, address: Gaojiayuan Residential Quarter, Chaoyang District, Beijing City.The main suit: the paroxysmal cough coughed up phlegm three days.History of present illness: the patient aversion to cold, low grade fever, throat pain, dry cough without phlegm occur after suffering from cold before three days, obeys infusion for treating coryza of wind cold type certainly after two days, still has low grade fever, pharyngalgia, paroxysmal cough, coughing up phlegm is the alternate mucus shape of white Huang, accompanies weak poor appetite.Outpatient service on August 1 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, the little Huang of white and thin fur, floating-rolling pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 3 days, therapeutic effect of syndrome reaches clinical cure.

Case 2 Yuan Gui English woman occupation in 25 years old: shop assistant, address: Chaoyang District, Beijing City Wang Si battalion.Main suit: cough pharyngalgia five days.History of present illness: beating appears in five days causes of patient flu back sneezes watery nasal discharge, limb acid backache, cough pharyngalgia, and clothes flu 3 days is invalid certainly, and the paroxysmal of still coughing is coughed up HUANGBAI(sic) and glued expectorant, and it is weak to have a headache.Outpatient service on August 24 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, white and thin fur, floating pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 4 days, therapeutic effect of syndrome reaches clinical cure.

Case 3 Zhao have cloud woman occupation in 45 years old: peasant, address: new city village, Xing Shou town, ChangPing, Beijing City district.The main suit: cough was coughed up phlegm 7 days.History of present illness: the patient before 7 days behind the field work bathing suffer from cold and occur that sneeze, rhinorrhea, headache body are stranded, pharyngalgia dry cough, flu takes a turn for the better after local hospitalize, still cough is more than, coughs up the alternate sticking expectorant of HUANGBAI(sic), amount is many.Outpatient service on July 24 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, and tongue is thick in vain, rolling pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 4 days, therapeutic effect of syndrome reaches clinical cure.

Case 4 China man occupation in 41 years old: workman, address: Beijing city flower township meat processing combine.Main suit: pharyngalgia cough 4 days.History of present illness: the patient pharyngalgia occurs after catching a cold before 4 days, and cough paroxysmal is coughed up yellow sputum, and is invalid through infusion treatment, accompanies weak poor appetite.Outpatient service on July 14 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, floating and rapid pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 3 days, therapeutic effect of syndrome reaches clinical cure.

Case 5 Zhao woman's occupation in 49 years old of holding high up for a short time: businessman, address: sub-district in Dingan County, Fengtai District, Beijing City Liu Jia cellar for storing things.Main suit: cough pharyngalgia 4 days.History of present illness: the patient caught a cold before 4 days and causes throat pain, cough paroxysmal, and companioned with headache is weak.Outpatient service on August 17 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, floating and rapid pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 4 days, therapeutic effect of syndrome reaches clinical cure.

Case 6 Liu Bin man occupation in 27 years old: company clerk, address: No. 6, backstreet, west, The Big Red Gate, Fengtai District, Beijing City.Main suit: cough pharyngalgia 2 days.History of present illness: the patient had a cold before 2 days and causes flu, aversion to cold headache, and the tired power of limb, the dry pharynx pharyngalgia, cough is coughed up phlegm, a small amount of yellow sputum, it is invalid to obey coldrex certainly.Outpatient service on August 21 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, floating-rolling pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 3 days, therapeutic effect of syndrome reaches clinical cure.

The blue woman of case 7 Liu Qing occupation in 35 years old: do not have the address: the red door in west, Fengtai District, Beijing City.Main suit: cough pharyngalgia 5 days.History of present illness: the patient met cold flu before 5 days, itching throat is then coughed, and coughs up yellow sputum, was difficult for bringing up, and companion's hyperhidrosis is weak.Outpatient service on August 3 in 2003 is had a medical check-up: two pulmonary respiration sounds are clear, red tongue, yellow and thin fur, floating pulse.Diagnosis: acute bronchitis.Treatment gives cough with asthma flat granule, every day three times, and each one bag, to take and do not have cough and cough up phlegm with examining in 3 days, therapeutic effect of syndrome reaches clinical cure.

Claims

1, a kind of drug particles for the treatment of cough with asthma is characterized in that: it is by Herba Ephedrae, Cortex Mori, stir-baked SEMEN ARMENIACAE AMARUM, Flos Inulae, Rhizoma Pinelliae Preparata, Radix Scutellariae, Folium Eriobotryae, Bulbus Fritillariae Cirrhosae, Bombyx Batryticatus(processed), honey-fried RADIX ASTERIS, the Radix Paeoniae Alba, Radix Glycyrrhizae, Semen Persicae, Flos Carthami, day is that raw material is made with shell, Concha Meretricis seu Cyclinae, glycyrrhizin, chlorphenamine maleate, diprophylline and Hydrochloric acid raceanisodamine;

Specifically filling a prescription by the above-mentioned raw materials order is 10: 10: 8 by weight: 8: 8: 8: 6: 4: 9: 9: 6: 6: 4: 4: 10: 10: 0.001: 0.0001: 0.002: 0.0002;

Preparation method is as follows: get Bulbus Fritillariae Cirrhosae by prescription, be ground into 100 order fine powders, other gets all the other 15 flavor Chinese crude drugs, decocts with water secondary, adds 10 times of amounts of water for the first time, decocts 1.5 hours, filters, and collects filtrate; For the second time add 6 times of amounts of water, decocted 1 hour, filter, merging filtrate, filtrate decompression is condensed into cream, spray drying, get fine powder, add dextrin, and with above-mentioned Bulbus Fritillariae Cirrhosae fine powder, glycyrrhizin, chlorphenamine maleate, diprophylline, Hydrochloric acid raceanisodamine mix homogeneously, do extruding and granulate, packing, packing, the co-60 radiation sterilization promptly gets product.