CN1003489B - Radiation apparatus producing local negative pressure and laser or redioactive ray - Google Patents

Radiation apparatus producing local negative pressure and laser or redioactive ray Download PDF

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Publication number
CN1003489B
CN1003489B CN85109066.4A CN85109066A CN1003489B CN 1003489 B CN1003489 B CN 1003489B CN 85109066 A CN85109066 A CN 85109066A CN 1003489 B CN1003489 B CN 1003489B
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China
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application device
laser
negative pressure
optical fibers
radioactive source
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CN85109066.4A
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CN85109066A (en
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董国臣
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Individual
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Priority to CN85109066.4A priority Critical patent/CN1003489B/en
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Abstract

The present invention relates to a radiation apparatus producing local negative pressure and laser or radioactive rays, which is a medical apparatus aiming at carrying out laser or radioactive ray treatment by producing local negative pressure on a human body. A negative pressure applicator is made of optical glass K9 and is plated with medium anti-reflection films or total reflection films on both surfaces; tumors in a local negative pressure region are radiated and treated by lasers passing the optical glass K9, or a laser coupled with an optical fiber built in the applicator, or a radioactive source built in the applicator; the device can also be combined with looking glass to carry out negative pressure laser radioactive ray treatment. The present invention has unique functions when used for carrying out negative pressure laser treatment on various diseases, and the present invention can also be used for the experimental treatment and the diagnosis of animal-transplanted tumors.

Description

A kind of radiotherapy unit
Gravitation makes the hyperemia of body local organization height, even local capillary rupture, thereby produces congestion, oneself haemolysis occurs, plays a kind of optimal stimulation effect.(2) the negative pressure stimulation can have influence on central nervous system's functional status, and reflexive causes that a series of generals and locality change, and adjusts cerebral cortex excitement and process of inhibition, eliminates a disease, recovers each normal function of health thereby reach.(3) adjust microcirculation and improve metabolism, make blood capillary and lymphatic vessel diastole, promote local circulation, improve local organization nutrition.(4) the negative pressure stimulation is on the acupuncture points on the human body of body surface.The same with acupuncture, play the regulating menstruation and activating blood effect.
Laser is being removed on the clinical medicine beyond treatment such as curing, welding, gasification, finishing tool, irradiation uses, and laser cooperates fibre-optic application, for various body cavitys treatments and sight glass inspection provide more favourable means.Utilize the effect of inspiring biology of tissue by laser clinically and to the pause and transition in rhythm or melody effect of symptom, the effect that reaches antiinflammatory, pain relieving, impels tissue regeneration and bring high blood pressure down.Because laser has a series of special performance, is also occurring many new techniques aspect diagnosing tumor and the treatment, the photosensitizer hematoporphyrin derivative laser diagnosis and treatment malignant tumor of studying has obtained obvious effects both at home and abroad.
According to the oncotherapy theory, to killing and wounding of weary oxygen and insensitive tumor cell, recurrence and transfer are two ten minutes major issues that exist on the oncotherapy.Tumor tissues is under suction function, and the blood of its surrounding tissue, lymph fluid rely on negative pressure to be drawn in tumor tissues, and the liquid in the tumor tissues is in and draws a state and be pulled to negative pressuren zone, causes local congestion or hemorrhage, and does not flow outside the local decompression district.Tumor cell can not spread because of being upset and shift in therapeutic process, and clinical practice is verified, and the tumor tissues that several blood supplies are good is good to the radiation-sensitive therapeutic effect; The tumor tissues inner blood is supplied, blood oxygen pressure and total oxygen-supplying amount increase, and blood oxygen diffusivity improves, and show the effect of partial high pressure oxygen, to the tumor tissues that contains photosensitizer hematoporphyrin derivative the quantum yield that produces singlet oxygen is increased, improved fragmentation effect tumor.
But, the device that also local decompression's therapy is not used in combination with laser, lonizing radiation in the world, according to the invention thought of above introduction, the inventor is at the problems referred to above design and developed the local negative pressure and laser radiotherapy apparatus.
The objective of the invention is,, not only can improve the curative effect of photodynamics and radiation cure tumor, and can prevent in therapeutic process the tumor cell diffusion and shift local decompression's therapy and laser, radiation cure combination; Can improve the partial hyperbaric oxygen effect of negative pressure in conjunction with the oxygen suction, can replace hyperbaric oxygen that multiple diseases such as thromboangiitis obliterans, gas gangrene are carried out topical therapeutic, or carry out Synergistic treatment and diagnosis with laser irradiation.
Principle of the present invention is, pump or vacuum pump connect the negative pressure application device, and to the local negative pressure that produces of body, laser sees through by K 9The negative pressure application device that optical glass is made, or laser instrument and the optical fibers Rhizoma Nelumbinis that is built in application device close tumor or other focus irradiation treatments to negative pressuren zone, or the radioactive source that is built in application device carries out radiotherapy to the tumor of local negative pressuren zone.Except that being used for not showing tumor and the other diseases, application device importing esophagus, stomach, vagina and the internal rectum that also can combine with sight glass small-sized built-in optical fibers or radioactive source carry out irradiation treatment under the negative pressure.
The power source of local decompression's device uses the pump of the one-way cock that has vacuometer, can make local decompression greater than 380 holders continuously to local suction, and vacuum is greater than 50%, and general vacuum is exceeded with the body tolerance.The electricity consumption vacuum pump, 0.2 liter of speed of exhaust per second, end vacuum 5 * 10 -4Holder, the air-breathing mouth of pipe of vacuum pump is equipped with valve, regulates negative pressure intensity.Be connected with pressure hose between the air-breathing mouth of pipe of pump or vacuum pump and application device, tee T of middle peace, optical fibers is introduced in the application device by tee T one end.
The negative pressure application device is partly made with the optical glass that is different from pottery, glass and metal and plastics fully, and rectangle, square, garden shape, ellipse garden shape, crooked shape limit etc. are arranged.Optical glass can be K 9Optical glass is according to the application device K that varies in size 91~5 millimeter of optical glass thickness, small size 1 millimeters thick of selecting for use, large size select 5 millimeters thick for use, withstand voltage every square centimeter more than 1.5 kilograms, application device rim of a cup diameter is 18 centimetres to the maximum, minimum 0.6 centimetre, can establish 18~20 kinds of big ting models therebetween, selecting big or small rim of a cup during treatment for use is to cover focus and tumor, also should cover 0.5~0.2 centimetre of normal structure on every side.Application device top or sidewall are offered long 2~3 centimetres an of mouth of pipe, are the garden taper, bore bottom opening in application device, 0.3~2.0 centimetre of diameter, and 0.2~1.8 centimetre of cone top part internal diameter, the pipe outer wall is a spiral type, is convenient to tube socket with fixing.
The K of application device 9Optical glass is according to the laser irradiation mode difference, and the anti-reflection deielectric-coating of two-sided plating can directly be injected for laser beam, or with rotatable completely reflecting mirror laser beam is reflexed in the application device from each different angle in 1~5 meter outside application device.The anti-reflection medium that plates selected according to using Wavelength of Laser.During the built-in optical fibers of application device, K 9Optical glass plating total reflection medium film is reflected on the photographed object laser beam of optical fibers luminous body, according to the 〈 ﹠﹠ that uses fully in application device〉total reflection medium film, it is two-sided to see through plating
A kind of radiotherapy unit relates to the technology of local decompression, laser and lonizing radiation, the invention belongs to technical field of medical instruments.
In the technology that formerly has, the earliest be Chinese (Chinese) cupping therapy.With the small cupping of an end opening, rely on the method for combustion paper heating, burn and drive away jar in a portion gas, and then opening is anchored on the therapentic part of human body, just can obtain the vacuum of 4/5 atmospheric pressure in jar, promptly be equivalent to 608 pressure that hold in the palm.Development along with society, the application of (Chinese) cupping therapy and therapeutic domain are also in constantly reform and expansion, local decompression's therapeutic equipments with the modern technologies development has appearred, the ZK5 vacuum cupping instrument that LZX-III type vacuum-therapy instrument that China Hangzhou medical apparatus and instruments factory produces and Huangyan medical apparatus and instruments factory produce, and local decompression's therapy apparatus of Japan etc.The common feature of these local decompression's therapeutic equipmentss, it is exactly the (Chinese) cupping therapy that replaces China with vacuum cupping instrument and electrovacuum massotherapy, though than (Chinese) cupping therapy safety, easy, range of application is identical with (Chinese) cupping therapy with clinical effectiveness, is mainly used in the rehabilitation of chronic disease.
In recent years, mechanism research to Chinese (Chinese) cupping therapy and electrovacuum therapeutic instrument is thought, local decompression makes the intravital flow of liquid of machine, be pulled outwardly by ambient as blood lymph fluid, tissue fluid etc., as the rope of tension, be in and draw a state, have negative pressure P=-F/A, here-and F is the suction force of vacuum pump or pump, A is the bore area of application device (cupping).Local decompression has the effect of human body: (1) mechanism produces the corresponding K that inhales anti-reflection deielectric-coating 9The laser power loss of optical glass is less than 5%.
The built-in optical fibers of application device is fed in the device by the suction nozzle of application device, adorn the tee T of a rigid plastics or metal between the pressure hose of connection application device and electrovacuum pump or pump, a mouth of pipe of tee T compresses with the soft rubber plug, plug central authorities pass through aspirating air pipe to application device optical fibers, compress the soft rubber plug and prevent gas leakage.There is four kinds on full garden column type, ball-type, extending type and pin type on fibre-optic top, the light angle of divergence is increased, the hot spot area coverage enlarges, overcome common fibre-optic shortcoming, and have multiple radiation modality, and the optical fibers core diameter of use is more than 20 microns, and skin is made the luminous body lasso trick with 2 millimeters polytetrafluoroethylene, bending radius 40 * core diameter, the vertical luminous body length of optical fibers is 0.5~3 centimetre.The optical fibers light-conductive rate is greater than 70%.
The Rhizoma Nelumbinis of laser instrument and optic fiber end face is closed, and the focal length of selecting condenser lens for use is less than optical fibers numerical aperture angle, and spot diameter is less than fibre-optic cross section.Condenser lens is embedded in the lens barrel that light metal or plastics make, long 5~6 centimetres of lens barrel, and lens barrel is connected with the laserresonator outfan, and central authorities have the axle center that optical fibers can be installed in the lens barrel, and the cutting of optic fiber end face usefulness diamond cutter can obtain smooth end face.
The present invention has reformed the content and structure of domestic and international existing vacuum cupping instrument, vacuum-therapy instrument, local decompression's therapy apparatus, overcome the shortcoming of the single effect of Chinese (Chinese) cupping therapy, vacuum cupping instrument etc., can not with the bonded defectives of new technique such as modern laser, lonizing radiation, and can not be used for the deficiency of the disease treatments such as tumor of serious harm human health, the negative pressure application device is partly with the K that is different from pottery, glass, metal or plastics fully 9Optical glass is made various difformities and big ting model, with K 9Optical glass two-sided plating medium anti-reflection film or total reflection medium film, make laser beam and laser instrument Rhizoma Nelumbinis close optical fibers local negative pressuren zone is carried out laser radiation, or application device is implanted into radioactive source and carries out radiation exposure treatment, makes local decompression's therapy and laser, radiation cure organically combine into a kind of new medical treatment device.Vacuum laser treatment and local decompression's laser point irradiation that this device also can be used for multiple disease carry out the laser acupuncture and moxibustion treatment, and disease is produced unique therapeutical effect, and do not have the effect of paying and painful, operation and easy to use.
The present invention also can be used for the diagnosis and the treatment of animal-transplanted tumor.
Description of drawings:
Fig. 1, local decompression's laser irradiation
1, vacuum pump 2, venting valve 3, admission air valve 4, one-way intake valve 5, pump 6, withstand voltage connection flexible pipe 7, U-shaped pipe vacuometer 8, body tissue 9, K 9Optical glass application device 10, completely reflecting mirror 11, laser beam 12, laser instrument
Fig. 2, local decompression laser instrument Rhizoma Nelumbinis are closed the optical fibers irradiation
1, vacuum pump 2, venting valve 3, admission air valve 4, one-way intake valve 5, pump 6, withstand voltage connection flexible pipe 7, U-shaped pipe vacuometer 8, body tissue 9, K 9Optical glass application device 10, optical fibers top luminous body 11, optical fibers 12, rubber closure fixed mount 13, lens barrel 14, condenser lens 15, laser beam 16, laser instrument
Fig. 3, local decompression's radiation exposure
1, vacuum pump 2, venting valve 3, admission air valve 4, one-way intake valve 5, pump 6, withstand voltage connection flexible pipe 7, U-shaped pipe vacuometer 8, body tissue 9, the application device 10 of liner sheet lead, radioactive source

Claims (12)

1, a kind of radiotherapy unit, has radioactive source, it is characterized in that it comprises that also a negative pressure application device partly becomes the device that can see through laser and lonizing radiation with the optics glass, with a vacuum extractor that has vacuometer, vacuum extractor is connected with the negative pressure application device with pressure hose, and the ray that radioactive source sends is incident on the interior negative pressuren zone of negative pressure application device.
2, device according to claim 1 is characterized in that radioactive source wherein is laser instrument, X-ray machine or other radiography unit.
3, device according to claim 1 is characterized in that vacuum extractor wherein is pump or vacuum pump.
4, device according to claim 1 is characterized in that wherein the optical glass of negative pressure application device can be the K of the anti-reflection deielectric-coating of two-sided plating 9Optical glass, laser and lonizing radiation are directly injected, or in 1~5 meter of application device, reflex to negative pressuren zone in the application device from all angles with rotatable completely reflecting mirror, make laser beam see through to according to the laser power loss in district less than 5%, the anti-reflection deielectric-coating of choosing plating is by the optical maser wavelength decision of using.
5, device according to claim 1, it is characterized in that wherein the shape of negative pressure application device has rectangle, square, garden cylindricality etc., rim of a cup has wealthy limit, shape limit, garden, crooked shape limit etc., is 0.6~18 centimetre according to big ting model rim of a cup diameter, and cup is high 1~10 centimetre, thick 1~5 millimeter, every square centimeter withstand voltage more than 1.5 kilograms, and application device top or sidewall suction nozzle are taper, long 1~4 centimetre, 0.3~2.0 centimetre of cone bottom diameter, 0.2~1.8 centimetre of tip diameter.
6, device according to claim 1, it is characterized in that wherein application device inwall plating total reflection medium film, make the laser of optical fibers top luminous body in application device, all reflect the tissue that impinges upon in the local decompression district, plate which kind of total reflection medium film, by the optical maser wavelength decision of using.
7, device according to claim 1, the interior wall liner of application device that it is characterized in that wherein keeping radioactive source is selected the thickness of sheet lead for use with certain thickness sheet lead according to the dosage of the radioactive source that uses.
8, device according to claim 1 is characterized in that application device rim of a cup diameter wherein is 1~2 centimetre, the built-in optical fibers of high 0.8~1.2 centimetre garden cylindricality or the small-sized application device of radioactive source, can insert intracavity under the guiding of sight glass.
9, according to claim 1,2 described radioactive source laser instrument, it is characterized in that wherein importing the optical fibers in the application device, one end is entered in the application device by an end of the tee T that is connected between application device and vacuum pump, soft rubber plug center hub is installed the optical fibers of 20~400 microns core diameters in the mouth of pipe, luminous conductor is outer makes lasso trick with four fluorine ethylenes, flexibility is 40 * core diameter, and the compress rubber plug makes ferrule prevent gas leakage, the optical fibers other end and the coupling of laserresonator outfan.
10, according to claim 1,2 described radioactive source laser instrument, it is characterized in that there are full garden cylindricality, sphere, expansion bundle shape and laser accunputure shape etc. in the optical fibers top that wherein imports in the application device, long 0.5~3 centimetre of optical fibers top luminous body, light-conductive rate is more than 70%.
11, according to claim 1,2 described radioactive source laser instrument, the focal length that it is characterized in that the condenser lens of the coupling of optical fibers and laser resonant cavity outfan wherein is less than optical fibers numerical aperture angle, spot diameter is less than fibre-optic cross section, condenser lens is embedded in the lens barrel of the light metal of 2~3 centimetres of 3~6 centimeter length, internal diameter or plastics, be connected with spiral with the laser resonant cavity outfan, center hub is installed end face and is cut smooth optical fibers with the diamond cutter in the lens barrel.
12, according to claim 1,3 described vacuum extractor pumps, it is characterized in that wherein the air-breathing mouth of pipe of pump has an one-way cock, can bleed to application device continuously, negative pressure intensity is not less than 380 holders, the speed of exhaust can reach 0.2 liter each second, and the vacuum in the local decompression district can reach more than 50%.
CN85109066.4A 1985-12-16 1985-12-16 Radiation apparatus producing local negative pressure and laser or redioactive ray Expired CN1003489B (en)

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Application Number Priority Date Filing Date Title
CN85109066.4A CN1003489B (en) 1985-12-16 1985-12-16 Radiation apparatus producing local negative pressure and laser or redioactive ray

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CN85109066.4A CN1003489B (en) 1985-12-16 1985-12-16 Radiation apparatus producing local negative pressure and laser or redioactive ray

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CN1003489B true CN1003489B (en) 1989-03-08

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100370280C (en) * 2003-06-30 2008-02-20 柯尼卡美能达精密光学株式会社 Optical element and optical pickup device

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1034106C (en) * 1994-10-01 1997-02-26 黄益富 Dynamic monitoring semiconductor laser therapeutic apparatus for irradiation in blood vessel
WO2011073882A1 (en) * 2009-12-16 2011-06-23 Koninklijke Philips Electronics N.V. Light treatment system
CN110141497A (en) * 2019-05-23 2019-08-20 刘芳 A kind of tumour electrotherapeutic therapy apparatus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100370280C (en) * 2003-06-30 2008-02-20 柯尼卡美能达精密光学株式会社 Optical element and optical pickup device

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