CN100340454C - Method for pouring liquid and solid in anti-adhersive multi-chamber perfusion bag made of non-PCV film - Google Patents
Method for pouring liquid and solid in anti-adhersive multi-chamber perfusion bag made of non-PCV film Download PDFInfo
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- CN100340454C CN100340454C CNB2005100315411A CN200510031541A CN100340454C CN 100340454 C CN100340454 C CN 100340454C CN B2005100315411 A CNB2005100315411 A CN B2005100315411A CN 200510031541 A CN200510031541 A CN 200510031541A CN 100340454 C CN100340454 C CN 100340454C
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- Prior art keywords
- solid
- coyote hole
- dress
- liquid
- medicine
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- 239000007787 solid Substances 0.000 title claims abstract description 42
- 239000007788 liquid Substances 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims abstract description 14
- 230000010412 perfusion Effects 0.000 title claims description 10
- 229940126589 solid medicine Drugs 0.000 claims abstract description 17
- 230000001954 sterilising effect Effects 0.000 claims abstract description 15
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 14
- 239000003814 drug Substances 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims abstract description 10
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000001307 helium Substances 0.000 claims abstract description 3
- 229910052734 helium Inorganic materials 0.000 claims abstract description 3
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 claims abstract description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 3
- 241000282470 Canis latrans Species 0.000 claims description 38
- 239000012528 membrane Substances 0.000 claims description 15
- 239000007789 gas Substances 0.000 claims description 5
- 239000003978 infusion fluid Substances 0.000 abstract description 2
- 239000011261 inert gas Substances 0.000 abstract 2
- 230000000181 anti-adherent effect Effects 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 238000000275 quality assurance Methods 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005429 filling process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The present invention relates to an anti-adhesive method for filling a liquid-solid type non-PVC film multi-chamber bad for infusion solutions. The method comprises the processing steps: making a bag, filling and sealing liquid medicine, sterilizing the liquid medicine, cutting a solid medicine chamber, and filling and sealing solid medicine. A solid medicine is filled with clean air or inert gas with no pollution before sterilization. The inert gas is nitrogen or helium. The present invention can cause two films of the solid medicine chamber not to stick with each other and has the characteristics of product quality assurance, the reduction of reject rate and defective rate, economic benefit increase, etc.
Description
Technical field
The invention belongs to the medical packaging field, be specifically related to the improvement of big transfusion multi-chamber bag perfusion method.
Background technology
Existing liquid and solid non-PVC membrane big transfusion multi-chamber bag (is example with two chambers bag) as shown in Figure 1, mainly by dress liquid coyote hole 3, dress solid coyote hole 5, weak welding line 4 and take over 1, high strength weld seam 2 etc. forms.Because the liquid medicine must be sterilized by high temperature (110-121 degree) behind filling and sealing in the infusion solutions, and solid medicine (mainly referring to aseptic powder) can not be in down sterilization of high temperature (110-121 degree), so the can production technology of liquid and solid big transfusion multi-chamber bag is: and bag → liquid medicine can → dress liquid coyote hole seals → sterilizes → and solid coyote hole incision → solid medicine can → dress solid coyote hole seals.As shown in Figure 2, at first behind the bag with can of liquid medicine and good seal, wherein adorning the solid coyote hole also must seal, this mainly is to guarantee that dress solid coyote hole can be not contaminated when sterilization, also guaranteed dress solid medicine indoor aseptic anhydrous (this is the requirement of solid medicine packing container) after waiting the bacterium of having gone out simultaneously, the sterilization of half-blank as shown in Figure 2 back (ten thousand grades of workshops, bottle placer place are hundred grades) in the environment of cleaning is cut sack along line of cut 7 places, solid medicine is poured into and sack is sealed as shown in Figure 1.Because existing non-PVC membrane big transfusion bag if empty bag (dress solid coyote hole as shown in Figure 2) through high temperature (110-121 degree) sterilization after, the two membranes of bag can tightly stick together, thus can't be in bag the can medicine, waste product, substandard products appear.
Summary of the invention
Technical matters to be solved by this invention is to overcome the deficiencies in the prior art, provides a kind of and guarantees that the two membranes of sack can coherent anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion method after sterilization.
For solving the problems of the technologies described above, the technical solution used in the present invention is: anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion method of the present invention, comprise bag, the can of liquid coyote hole, seal, sterilization, the incision of solid coyote hole, can, sealing process step is characterized in that before sterilization at dress indoor filling pure air of solid medicine or clean unreactable gas.
The concrete processing step of the present invention is as follows: bag, the inflation of dress solid coyote hole, the sealing of dress solid coyote hole, the can of liquid medicine, dress liquid coyote hole seal, sterilize, adorn the incision of solid coyote hole, the can of dress solid medicine is sealed to adorning the solid coyote hole.Also can cut for bag, the can of liquid medicine, dress liquid coyote hole seal, adorn the inflation of solid coyote hole, the sealing of dress solid coyote hole, sterilization, dress solid coyote hole, the can of dress solid medicine seals to adorning the solid coyote hole.Described unreactable gas can be nitrogen, helium etc.
The present invention takes above-mentioned filling technological method effectively to guarantee, after the sterilization step, the two membranes of dress solid coyote hole can not stick together, thereby improves the quality of products, and reduces waste product, fraction defect, increases economic benefit.
Description of drawings
Fig. 1 is the finished product structural representation of liquid and solid non-PVC membrane big transfusion multi-chamber bag;
Fig. 2 is a half-blank structural representation in the liquid and solid non-PVC membrane big transfusion multi-chamber bag filling process of prior art;
Half-blank structural representation when Fig. 3 finishes for bag processing step among the present invention;
Fig. 4 is among the present invention, the half-blank structural representation when the dress indoor filling pure air of solid medicine or pollution-free unreactable gas processing step are finished.
Each label is represented among the figure:
1, adapter 2, high strength weld seam 3, dress liquid coyote hole
4, weak soldered 5, dress solid coyote hole 6, reservation perfusion mouth
7, line of cut
The specific embodiment
Embodiment 1: at first produce bag as shown in Figure 3, and will adorn the liquid coyote hole and adorn good seal behind the medicine, and then will adorn the indoor filling pure air of solid medicine the two membranes of dress solid coyote hole is not contacted, and will adorn the sealing of solid coyote hole as shown in Figure 4, bag after the sterilization is cut sack from diagram line of cut 7, powder is packed in the solid coyote hole, again sack is sealed as shown in Figure 1.
Claims (4)
1, a kind of anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion method, comprise bag, the can of liquid medicine, seal, sterilization, the incision of dress solid coyote hole, can, sealing process step is characterized in that before sterilization at dress indoor filling pure air of solid medicine or pollution-free unreactable gas.
2, anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion method according to claim 1 is characterized in that its concrete steps are followed successively by: bag, the inflation of dress solid coyote hole, the sealing of dress solid coyote hole, the can of liquid medicine, dress liquid coyote hole seal, sterilize, adorn the solid coyote hole and cut, adorn the solid medicine can and seal to adorning the solid coyote hole.
3, anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion method according to claim 1 is characterized in that its concrete steps are followed successively by: bag, the can of liquid medicine, dress liquid coyote hole seal, adorn that the inflation of solid coyote hole, the sealing of dress solid coyote hole, sterilization, dress solid coyote hole are cut, the can of dress solid medicine is sealed to adorning the solid coyote hole.
4, according to claim 1 or 2 or 3 described anti-bonding liquid and solid non-PVC membrane big transfusion multi-chamber bag perfusion methods, it is characterized in that described unreactable gas is: nitrogen or helium.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100315411A CN100340454C (en) | 2005-05-13 | 2005-05-13 | Method for pouring liquid and solid in anti-adhersive multi-chamber perfusion bag made of non-PCV film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100315411A CN100340454C (en) | 2005-05-13 | 2005-05-13 | Method for pouring liquid and solid in anti-adhersive multi-chamber perfusion bag made of non-PCV film |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1693140A CN1693140A (en) | 2005-11-09 |
| CN100340454C true CN100340454C (en) | 2007-10-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100315411A Expired - Fee Related CN100340454C (en) | 2005-05-13 | 2005-05-13 | Method for pouring liquid and solid in anti-adhersive multi-chamber perfusion bag made of non-PCV film |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100340454C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100443372C (en) * | 2006-04-26 | 2008-12-17 | 长沙楚天科技有限公司 | Automatic medicine-filling machine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05112307A (en) * | 1991-10-18 | 1993-05-07 | Ishizuka Glass Co Ltd | Method and device for producing bag for transfusion |
| JP2001314484A (en) * | 2000-05-08 | 2001-11-13 | Hideki Munekuni | Medical plural chamber container and manufacturing method thereof |
| JP2004337318A (en) * | 2003-05-14 | 2004-12-02 | Otsuka Pharmaceut Factory Inc | Medical double-chamber container and manufacturing method therefor |
-
2005
- 2005-05-13 CN CNB2005100315411A patent/CN100340454C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05112307A (en) * | 1991-10-18 | 1993-05-07 | Ishizuka Glass Co Ltd | Method and device for producing bag for transfusion |
| JP2001314484A (en) * | 2000-05-08 | 2001-11-13 | Hideki Munekuni | Medical plural chamber container and manufacturing method thereof |
| JP2004337318A (en) * | 2003-05-14 | 2004-12-02 | Otsuka Pharmaceut Factory Inc | Medical double-chamber container and manufacturing method therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1693140A (en) | 2005-11-09 |
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