CL2020002858A1 - Nuevos péptidos (seq id no: 203) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096). - Google Patents

Nuevos péptidos (seq id no: 203) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096).

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Publication number
CL2020002858A1
CL2020002858A1 CL2020002858A CL2020002858A CL2020002858A1 CL 2020002858 A1 CL2020002858 A1 CL 2020002858A1 CL 2020002858 A CL2020002858 A CL 2020002858A CL 2020002858 A CL2020002858 A CL 2020002858A CL 2020002858 A1 CL2020002858 A1 CL 2020002858A1
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Chile
Prior art keywords
peptides
new
seq
nhl
hodgkin
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CL2020002858A
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English (en)
Inventor
Toni Weinschenk
Jens Fritsche
Andrea Mahr
Anita Wiebe
Oliver Schoor
Harpreet Singh
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Immatics Biotechnologies Gmbh
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Priority claimed from GBGB1602918.3A external-priority patent/GB201602918D0/en
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of CL2020002858A1 publication Critical patent/CL2020002858A1/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/0011Cancer antigens
    • A61K39/001193Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
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    • A61K39/4644Cancer antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/70539MHC-molecules, e.g. HLA-molecules
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
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    • G01MEASURING; TESTING
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    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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Abstract

La presente invención se refiere a péptidos (SEQ ID NO: 203), proteínas, ácidos nucleicos y células destinados a la utilización en métodos inmunoterapéuticos. En particular, la presente invención se refiere a la inmunoterapia contra el cáncer. La presente invención se refiere asimismo a epítopos peptídicos para linfocitos T asociados a tumores, solos o en combinación con otros péptidos asociados a tumores que, por ejemplo, pueden servir como principios activos farmacéuticos en composiciones vacunales destinadas a estimular respuestas inmunitarias antitumorales, o a estimular ex vivo linfocitos T que después serán <br /> transferidos a los pacientes. Los péptidos unidos a moléculas del complejo mayor de histocompatibilidad (MHC), o los péptidos como tales, también pueden ser dianas de anticuerpos, de receptores de linfocitos T solubles, y de otras moléculas de unión.
CL2020002858A 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 203) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096). CL2020002858A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662297495P 2016-02-19 2016-02-19
GBGB1602918.3A GB201602918D0 (en) 2016-02-19 2016-02-19 Novel peptides and combination of peptides for use in immunotherapy against NHL and other cancers

Publications (1)

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CL2020002858A1 true CL2020002858A1 (es) 2021-04-09

Family

ID=58057145

Family Applications (4)

Application Number Title Priority Date Filing Date
CL2018002096A CL2018002096A1 (es) 2016-02-19 2018-08-03 Nuevos péptidos y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer
CL2020002858A CL2020002858A1 (es) 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 203) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096).
CL2020002857A CL2020002857A1 (es) 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 146) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096)
CL2020002856A CL2020002856A1 (es) 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 120) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096)

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CL2018002096A CL2018002096A1 (es) 2016-02-19 2018-08-03 Nuevos péptidos y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer

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CL2020002857A CL2020002857A1 (es) 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 146) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096)
CL2020002856A CL2020002856A1 (es) 2016-02-19 2020-11-04 Nuevos péptidos (seq id no: 120) y nuevas combinaciones de péptidos para el uso en la inmunoterapia contra el linfoma no hodgkiniano (lnh) y otros tipos de cáncer (divisional de la solicitud no. 201802096)

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US (5) US10702592B2 (es)
JP (4) JP2021040628A (es)
CN (1) CN114028549A (es)
CL (4) CL2018002096A1 (es)
CO (1) CO2018008239A2 (es)
MA (1) MA55153A (es)
PH (1) PH12018501639A1 (es)
ZA (1) ZA201805512B (es)

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JP2021040627A (ja) 2021-03-18
US10933125B2 (en) 2021-03-02
ZA201805512B (en) 2019-06-26
US20190314474A1 (en) 2019-10-17
US20210023190A1 (en) 2021-01-28
CL2020002857A1 (es) 2021-04-09
PH12018501639A1 (en) 2019-06-03
US10813986B2 (en) 2020-10-27
US10702593B2 (en) 2020-07-07
US20190336590A1 (en) 2019-11-07
CL2018002096A1 (es) 2018-09-14
US20200297831A1 (en) 2020-09-24
MA55153A (fr) 2021-09-29
JP2021040628A (ja) 2021-03-18
CN114028549A (zh) 2022-02-11
CO2018008239A2 (es) 2018-08-21
JP2021045124A (ja) 2021-03-25
JP2021035361A (ja) 2021-03-04
US20210154284A1 (en) 2021-05-27
CL2020002856A1 (es) 2021-04-09
US10702592B2 (en) 2020-07-07

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