CL2015002627A1 - Compositions for use in the treatment of eye disorders using dipyridamole - Google Patents
Compositions for use in the treatment of eye disorders using dipyridamoleInfo
- Publication number
- CL2015002627A1 CL2015002627A1 CL2015002627A CL2015002627A CL2015002627A1 CL 2015002627 A1 CL2015002627 A1 CL 2015002627A1 CL 2015002627 A CL2015002627 A CL 2015002627A CL 2015002627 A CL2015002627 A CL 2015002627A CL 2015002627 A1 CL2015002627 A1 CL 2015002627A1
- Authority
- CL
- Chile
- Prior art keywords
- treatment
- compositions
- dipiridamol
- preferibly
- eye disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
LA PRESENTE INVENCIÓN DESCRIBE COMPOSICIONES PARA EL USO EN EL TRATAMIENTO DE TRASTORNOS OCULARES, LAS COMPOSICIONES QUE INCLUYEN UNA CANTIDAD EFECTIVA DE UN DIPIRIDAMOL ADMINISTRADO TÓPICAMENTE. PREFERIBLEMENTE, EL DIPIRIDAMOL ADMINISTRADO TÓPICAMENTE ES FORMULADO COMO UNA SOIUCION. PREFERIBLEMENTE, EL DIPIRIDAMOL ADMINISTRADO TÓPICAMENTE ES AL MENOS UN AGENTE SELECCIONADO DEL GRUPO QUE CONSISTENTE DE: DIPIRIDAMOL, Y SU SAL FARMACÉUTICAMENTE ACEPTABLE. PREFERIBLEMENTE, LA CANTIDAD EFECTIVA CORRESPONDE A UNA CONCENTRACIÓN DE POR LO MENOS APROXIMADARNENTE UNA MOLARIDAD DE 10-5. PREFERIBLEMENTE, LA CANTIDAD EFECTIVA SE BASA EN LA ADMINISTRACIÓN DE UN TRATAMIENTO DE AL MENOS UNA VEZ CADA DOS DIAS.THIS INVENTION DESCRIBES COMPOSITIONS FOR USE IN THE TREATMENT OF EYE DISORDERS, COMPOSITIONS THAT INCLUDE AN EFFECTIVE AMOUNT OF A TYPICALLY ADMINISTERED DIPIRIDAMOL. PREFERIBLY, DIPIRIDAMOL ADMINISTERED TYPICALLY IS FORMULATED AS A SOIUTION. PREFERIBLY, THE TYPICALLY ADMINISTERED DIPIRIDAMOL IS AT LEAST AN AGENT SELECTED FROM THE GROUP THAT CONSISTS OF: DIPIRIDAMOL, AND ITS PHARMACEUTICALLY ACCEPTABLE SALT. PREFERIBLY, THE EFFECTIVE AMOUNT CORRESPONDS TO A CONCENTRATION OF AT LEAST APPROXIMATELY A 10-5 MOLARITY. PREFERIBLY, THE EFFECTIVE AMOUNT IS BASED ON THE ADMINISTRATION OF A TREATMENT OF AT LEAST ONCE EVERY TWO DAYS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL225179A IL225179A (en) | 2013-03-12 | 2013-03-12 | Compositions for use in treating eye disorders using dipyridamole |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2015002627A1 true CL2015002627A1 (en) | 2016-03-11 |
Family
ID=48916407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2015002627A CL2015002627A1 (en) | 2013-03-12 | 2015-09-11 | Compositions for use in the treatment of eye disorders using dipyridamole |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP2968328A4 (en) |
JP (1) | JP6820658B2 (en) |
KR (2) | KR20150126021A (en) |
CN (1) | CN105188702B (en) |
AU (1) | AU2014229371B2 (en) |
BR (1) | BR112015022084A2 (en) |
CA (1) | CA2905594A1 (en) |
CL (1) | CL2015002627A1 (en) |
EA (1) | EA035966B1 (en) |
IL (1) | IL225179A (en) |
MX (1) | MX2015012716A (en) |
MY (1) | MY182591A (en) |
SG (2) | SG10201706937UA (en) |
WO (1) | WO2014141079A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107106541A (en) * | 2015-01-28 | 2017-08-29 | 瑞采生技有限公司 | Compound and its medical application for strengthening PPAR γ performances and nuclear translocation |
US20180092776A1 (en) | 2016-09-30 | 2018-04-05 | Sara Heikali | Method and device for treating and managing diseased ocular tissue |
WO2021001805A1 (en) | 2019-07-04 | 2021-01-07 | Ocular Discovery Ltd. | Stable dipyridamole formulations and their methods of preparation |
WO2021001806A1 (en) | 2019-07-04 | 2021-01-07 | Ocular Discovery Ltd. | Stable dipyridamole formulations with reduced impurities |
WO2024125322A1 (en) * | 2022-12-16 | 2024-06-20 | 智泽童康(广州)生物科技有限公司 | Dipyridamole for preventing and treating allergic and/or inflammatory diseases and preparation thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07258084A (en) * | 1994-03-17 | 1995-10-09 | Rohto Pharmaceut Co Ltd | Intracular pressure-reducing agent containing dipyridamole as essential component |
US5780450A (en) * | 1995-11-21 | 1998-07-14 | Alcon Laboratories, Inc. | Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage |
US20060104968A1 (en) * | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
AU2006311577B2 (en) * | 2005-11-09 | 2013-02-07 | Zalicus Inc. | Methods, compositions, and kits for the treatment of medical conditions |
WO2010056710A1 (en) * | 2008-11-11 | 2010-05-20 | Biovista, Inc. | Compositions and methods for treating eye diseases |
EP2363126A1 (en) * | 2010-03-04 | 2011-09-07 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation |
-
2013
- 2013-03-12 IL IL225179A patent/IL225179A/en active IP Right Grant
-
2014
- 2014-03-11 AU AU2014229371A patent/AU2014229371B2/en not_active Ceased
- 2014-03-11 MX MX2015012716A patent/MX2015012716A/en unknown
- 2014-03-11 MY MYPI2015002196A patent/MY182591A/en unknown
- 2014-03-11 CN CN201480016302.6A patent/CN105188702B/en not_active Expired - Fee Related
- 2014-03-11 WO PCT/IB2014/059645 patent/WO2014141079A1/en active Application Filing
- 2014-03-11 EA EA201591653A patent/EA035966B1/en unknown
- 2014-03-11 SG SG10201706937UA patent/SG10201706937UA/en unknown
- 2014-03-11 EP EP14764673.1A patent/EP2968328A4/en not_active Withdrawn
- 2014-03-11 BR BR112015022084A patent/BR112015022084A2/en active Search and Examination
- 2014-03-11 JP JP2015562486A patent/JP6820658B2/en active Active
- 2014-03-11 KR KR1020157027571A patent/KR20150126021A/en not_active IP Right Cessation
- 2014-03-11 KR KR1020217001495A patent/KR20210010638A/en not_active Application Discontinuation
- 2014-03-11 SG SG11201507092QA patent/SG11201507092QA/en unknown
- 2014-03-11 CA CA2905594A patent/CA2905594A1/en not_active Abandoned
-
2015
- 2015-09-11 CL CL2015002627A patent/CL2015002627A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG11201507092QA (en) | 2015-10-29 |
IL225179A (en) | 2017-01-31 |
JP2016514123A (en) | 2016-05-19 |
MX2015012716A (en) | 2016-07-06 |
SG10201706937UA (en) | 2017-09-28 |
CA2905594A1 (en) | 2014-09-18 |
BR112015022084A2 (en) | 2017-07-18 |
EA201591653A1 (en) | 2017-05-31 |
MY182591A (en) | 2021-01-26 |
JP6820658B2 (en) | 2021-01-27 |
EP2968328A4 (en) | 2016-11-23 |
KR20210010638A (en) | 2021-01-27 |
CN105188702A (en) | 2015-12-23 |
KR20150126021A (en) | 2015-11-10 |
CN105188702B (en) | 2019-03-26 |
IL225179A0 (en) | 2013-06-27 |
EA035966B1 (en) | 2020-09-07 |
AU2014229371B2 (en) | 2018-05-10 |
WO2014141079A1 (en) | 2014-09-18 |
AU2014229371A1 (en) | 2015-10-29 |
EP2968328A1 (en) | 2016-01-20 |
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