CL2009001150A1 - Compuestos derivados de n-(2-amino-fenil)-acrilamidas, inhibidor de la histona-desacetilasa (hdac); procedimiento de preparacion; composicion faramceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer. - Google Patents
Compuestos derivados de n-(2-amino-fenil)-acrilamidas, inhibidor de la histona-desacetilasa (hdac); procedimiento de preparacion; composicion faramceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer.Info
- Publication number
- CL2009001150A1 CL2009001150A1 CL2009001150A CL2009001150A CL2009001150A1 CL 2009001150 A1 CL2009001150 A1 CL 2009001150A1 CL 2009001150 A CL2009001150 A CL 2009001150A CL 2009001150 A CL2009001150 A CL 2009001150A CL 2009001150 A1 CL2009001150 A1 CL 2009001150A1
- Authority
- CL
- Chile
- Prior art keywords
- compound
- acrylamides
- cancer
- phenyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compuestos derivados de n-(2-amino-fenil)-acrilamidas; procedimiento de preparación; composición farmacéutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cáncer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08156365 | 2008-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2009001150A1 true CL2009001150A1 (es) | 2010-06-11 |
Family
ID=40756614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2009001150A CL2009001150A1 (es) | 2008-05-16 | 2009-05-12 | Compuestos derivados de n-(2-amino-fenil)-acrilamidas, inhibidor de la histona-desacetilasa (hdac); procedimiento de preparacion; composicion faramceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer. |
Country Status (15)
Country | Link |
---|---|
US (1) | US7999000B2 (es) |
EP (1) | EP2280940A1 (es) |
JP (1) | JP2011519966A (es) |
KR (1) | KR20100132553A (es) |
CN (1) | CN102026969A (es) |
AR (1) | AR071790A1 (es) |
AU (1) | AU2009248231A1 (es) |
BR (1) | BRPI0912399A2 (es) |
CA (1) | CA2724003A1 (es) |
CL (1) | CL2009001150A1 (es) |
IL (1) | IL208873A0 (es) |
MX (1) | MX2010012297A (es) |
PE (1) | PE20100139A1 (es) |
TW (1) | TW200951110A (es) |
WO (1) | WO2009138338A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8202866B2 (en) * | 2008-09-17 | 2012-06-19 | Hoffmann-La Roche Inc. | Ortho-aminoanilides for the treatment of cancer |
MX2011008899A (es) * | 2009-02-23 | 2011-09-15 | Hoffmann La Roche | Nuevas orto-aminoamidas para el tratamiento del cancer. |
US9212132B2 (en) | 2011-12-05 | 2015-12-15 | Ricoh Company Ltd. | (Meth)acrylic acid ester, activation energy ray curing composition, and inkjet recording ink |
WO2014142255A1 (ja) | 2013-03-14 | 2014-09-18 | 武田薬品工業株式会社 | 複素環化合物 |
WO2015002230A1 (ja) | 2013-07-03 | 2015-01-08 | 武田薬品工業株式会社 | アミド化合物 |
WO2015002231A1 (ja) | 2013-07-03 | 2015-01-08 | 武田薬品工業株式会社 | 複素環化合物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1033046B (it) | 1970-10-31 | 1979-07-10 | Finotto Martino | Procedimento di fabbricazione di benzimidazoli sostituiti |
DE2201062A1 (de) | 1972-01-11 | 1973-07-26 | Bayer Ag | N-alkoxycarbonyl- bzw. n-alkylthiocarbonyl-2-(2'-thienyl)-benzimidazole, ein verfahren zu ihrer herstellung und ihre verwendung als fungizide |
WO2001038322A1 (en) * | 1999-11-23 | 2001-05-31 | Methylgene, Inc. | Inhibitors of histone deacetylase |
CN101851173A (zh) * | 2001-09-14 | 2010-10-06 | 梅特希尔基因公司 | 组蛋白脱乙酰化酶抑制剂 |
US7253204B2 (en) * | 2004-03-26 | 2007-08-07 | Methylgene Inc. | Inhibitors of histone deacetylase |
WO2006115845A1 (en) * | 2005-04-20 | 2006-11-02 | Merck & Co., Inc. | Benzothiophene derivatives |
AU2007208495A1 (en) | 2006-01-12 | 2007-08-02 | Merck Sharp & Dohme Corp. | Hydroxyalkylarylamide derivatives |
AU2007221207A1 (en) * | 2006-02-28 | 2007-09-07 | Merck Sharp & Dohme Corp. | Inhibitors of histone deacetylase |
EP2238103A1 (en) * | 2008-01-29 | 2010-10-13 | F. Hoffmann-La Roche AG | Novel n-(2-amino-phenyl)-amide derivatives |
-
2009
- 2009-05-06 MX MX2010012297A patent/MX2010012297A/es active IP Right Grant
- 2009-05-06 AU AU2009248231A patent/AU2009248231A1/en not_active Abandoned
- 2009-05-06 CN CN2009801175566A patent/CN102026969A/zh active Pending
- 2009-05-06 WO PCT/EP2009/055441 patent/WO2009138338A1/en active Application Filing
- 2009-05-06 BR BRPI0912399A patent/BRPI0912399A2/pt not_active IP Right Cessation
- 2009-05-06 KR KR1020107025623A patent/KR20100132553A/ko active IP Right Grant
- 2009-05-06 EP EP09745671A patent/EP2280940A1/en not_active Withdrawn
- 2009-05-06 CA CA2724003A patent/CA2724003A1/en not_active Abandoned
- 2009-05-06 JP JP2011508865A patent/JP2011519966A/ja active Pending
- 2009-05-11 US US12/463,452 patent/US7999000B2/en not_active Expired - Fee Related
- 2009-05-12 PE PE2009000647A patent/PE20100139A1/es not_active Application Discontinuation
- 2009-05-12 CL CL2009001150A patent/CL2009001150A1/es unknown
- 2009-05-14 TW TW098116054A patent/TW200951110A/zh unknown
- 2009-05-14 AR ARP090101736A patent/AR071790A1/es unknown
-
2010
- 2010-10-21 IL IL208873A patent/IL208873A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
TW200951110A (en) | 2009-12-16 |
BRPI0912399A2 (pt) | 2016-01-12 |
MX2010012297A (es) | 2010-12-06 |
CN102026969A (zh) | 2011-04-20 |
JP2011519966A (ja) | 2011-07-14 |
US20090286848A1 (en) | 2009-11-19 |
PE20100139A1 (es) | 2010-03-05 |
IL208873A0 (en) | 2011-01-31 |
EP2280940A1 (en) | 2011-02-09 |
US7999000B2 (en) | 2011-08-16 |
KR20100132553A (ko) | 2010-12-17 |
WO2009138338A1 (en) | 2009-11-19 |
AR071790A1 (es) | 2010-07-14 |
AU2009248231A1 (en) | 2009-11-19 |
CA2724003A1 (en) | 2009-11-19 |
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