CL2007003065A1 - Compounds derived from benzodioxane, 5ht2c agonist, pharmaceutical composition that you understand; and its use in the treatment of a psychotic disorder, anxiety, depression, bipolar disorder, premenstrual syndrome, among others - Google Patents
Compounds derived from benzodioxane, 5ht2c agonist, pharmaceutical composition that you understand; and its use in the treatment of a psychotic disorder, anxiety, depression, bipolar disorder, premenstrual syndrome, among othersInfo
- Publication number
- CL2007003065A1 CL2007003065A1 CL2007003065A CL2007003065A CL2007003065A1 CL 2007003065 A1 CL2007003065 A1 CL 2007003065A1 CL 2007003065 A CL2007003065 A CL 2007003065A CL 2007003065 A CL2007003065 A CL 2007003065A CL 2007003065 A1 CL2007003065 A1 CL 2007003065A1
- Authority
- CL
- Chile
- Prior art keywords
- benzodioxane
- anxiety
- depression
- pharmaceutical composition
- understand
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 208000020925 Bipolar disease Diseases 0.000 title abstract 2
- 206010036618 Premenstrual syndrome Diseases 0.000 title abstract 2
- 208000028017 Psychotic disease Diseases 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- LYKMMUBOEFYJQG-UHFFFAOYSA-N piperoxan Chemical compound C1OC2=CC=CC=C2OC1CN1CCCCC1 LYKMMUBOEFYJQG-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002485 serotonin 2C agonist Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Compuestos derivados de benzodioxano; composición farmacéutica que comprende a dichos compuestos; y su uso para tratar una enfermedad seleccionada entre trastornos psicóticos, tales como ansiedad, depresión, trastorno bipolar, síndrome premenstrual, entre otros.Compounds derived from benzodioxane; pharmaceutical composition comprising said compounds; and its use to treat a disease selected from psychotic disorders, such as anxiety, depression, bipolar disorder, premenstrual syndrome, among others.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85405506P | 2006-10-24 | 2006-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007003065A1 true CL2007003065A1 (en) | 2008-01-25 |
Family
ID=38941237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2007003065A CL2007003065A1 (en) | 2006-10-24 | 2007-10-24 | Compounds derived from benzodioxane, 5ht2c agonist, pharmaceutical composition that you understand; and its use in the treatment of a psychotic disorder, anxiety, depression, bipolar disorder, premenstrual syndrome, among others |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR063373A1 (en) |
| CL (1) | CL2007003065A1 (en) |
| TW (1) | TW200823187A (en) |
| WO (1) | WO2008052086A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2216023A4 (en) | 2007-11-15 | 2013-03-13 | Takeda Pharmaceutical | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF |
| US9814701B2 (en) | 2009-12-11 | 2017-11-14 | Aldeyra Therapeutics, Inc. | Compositions and methods for the treatment of macular degeneration |
| WO2011071136A1 (en) | 2009-12-11 | 2011-06-16 | アステラス製薬株式会社 | Therapeutic agent for fibromyalgia |
| WO2012030953A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
| EP2822941B1 (en) | 2012-03-06 | 2017-05-10 | Boehringer Ingelheim International GmbH | Benzodioxanes in combination with statins for inhibiting leukotriene production |
| EP2885285B1 (en) | 2012-07-17 | 2016-10-19 | Boehringer Ingelheim International GmbH | Pyrazole drivatives which inhibit leukotriene production |
| RU2676694C9 (en) | 2013-01-23 | 2019-06-25 | Альдейра Терапьютикс, Инк. | Toxic aldehyde related diseases and treatment |
| WO2015009611A1 (en) | 2013-07-15 | 2015-01-22 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
| WO2015009609A1 (en) | 2013-07-15 | 2015-01-22 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
| WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
| CN118724806A (en) | 2015-08-21 | 2024-10-01 | 奥尔德拉医疗公司 | Deuterated compounds and uses thereof |
| GB201801128D0 (en) * | 2018-01-24 | 2018-03-07 | Univ Oxford Innovation Ltd | Compounds |
| WO2020033344A1 (en) | 2018-08-06 | 2020-02-13 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CA3137301A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| WO2021231792A1 (en) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
| CA3220889A1 (en) * | 2021-07-02 | 2023-01-05 | Aldexa Therapeutics, Inc. | Heterocyclic aldehyde trapping compounds and uses thereof |
| US11957671B2 (en) | 2021-11-01 | 2024-04-16 | Alkahest, Inc. | Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2791675B1 (en) * | 1999-03-30 | 2001-05-04 | Synthelabo | DERIVATIVES OF N- [2- (4-AMINOPHENYL) ETHYL] -2,3-DIHYDRO-1,4- BENZODIOXINNE-2-METHANAMINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
| JP2003506370A (en) * | 1999-07-29 | 2003-02-18 | イーライ・リリー・アンド・カンパニー | Benzofurylpiperazine serotonin agonist |
| AU2002221670B2 (en) * | 2000-10-16 | 2006-11-02 | F. Hoffmann-La Roche Ag | Indoline derivatives and their use as 5-HT2 receptor ligands |
| SE0201544D0 (en) * | 2002-05-17 | 2002-05-17 | Biovitrum Ab | Novel compounds and thier use |
| CN101218223A (en) * | 2005-04-22 | 2008-07-09 | 惠氏公司 | Benzodioxane and benzodioxolane derivatives and uses thereof |
-
2007
- 2007-10-24 WO PCT/US2007/082450 patent/WO2008052086A1/en active Application Filing
- 2007-10-24 AR ARP070104705A patent/AR063373A1/en unknown
- 2007-10-24 CL CL2007003065A patent/CL2007003065A1/en unknown
- 2007-10-24 TW TW096139848A patent/TW200823187A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR063373A1 (en) | 2009-01-21 |
| WO2008052086A1 (en) | 2008-05-02 |
| TW200823187A (en) | 2008-06-01 |
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