CH609065A5 - Process for the preparation of 21-adamantoyloxysteroids - Google Patents

Process for the preparation of 21-adamantoyloxysteroids

Info

Publication number
CH609065A5
CH609065A5 CH1003472A CH1003472A CH609065A5 CH 609065 A5 CH609065 A5 CH 609065A5 CH 1003472 A CH1003472 A CH 1003472A CH 1003472 A CH1003472 A CH 1003472A CH 609065 A5 CH609065 A5 CH 609065A5
Authority
CH
Switzerland
Prior art keywords
adamantoyloxysteroids
preparation
Prior art date
Application number
CH1003472A
Other languages
English (en)
Inventor
Gordon Hanley Philipps
Alan Frederick English
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CH609065A5 publication Critical patent/CH609065A5/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1003472A 1971-07-05 1972-07-04 Process for the preparation of 21-adamantoyloxysteroids CH609065A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3134971A GB1391443A (en) 1971-07-05 1971-07-05 Ester of betamethasone and its 9alpha-chloro analogue

Publications (1)

Publication Number Publication Date
CH609065A5 true CH609065A5 (en) 1979-02-15

Family

ID=10321802

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1003472A CH609065A5 (en) 1971-07-05 1972-07-04 Process for the preparation of 21-adamantoyloxysteroids

Country Status (17)

Country Link
JP (1) JPS5644079B1 (da)
AR (2) AR194120A1 (da)
AU (1) AU464251B2 (da)
BE (1) BE785812A (da)
CA (1) CA983919A (da)
CH (1) CH609065A5 (da)
DE (1) DE2232827A1 (da)
DK (1) DK131474B (da)
FR (1) FR2144761B1 (da)
GB (1) GB1391443A (da)
IE (1) IE36529B1 (da)
IL (1) IL39821A (da)
NL (1) NL169882C (da)
NO (1) NO137754C (da)
PH (1) PH13195A (da)
SE (1) SE385904B (da)
ZA (1) ZA724598B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5024427A (da) * 1973-01-03 1975-03-15
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
JPS6163976U (da) * 1984-10-01 1986-05-01
KR101591482B1 (ko) 2008-05-28 2016-02-03 레베라겐 바이오파마 인코포레이티드 질환의 치료를 위한 NF-κB 의 비호르몬성 스테로이드 조절제
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
IL39821A (en) 1976-02-29
IE36529B1 (en) 1976-11-24
FR2144761B1 (da) 1976-03-05
FR2144761A1 (da) 1973-02-16
SE385904B (sv) 1976-07-26
BE785812A (fr) 1973-01-04
NL169882B (nl) 1982-04-01
AU4420572A (en) 1974-01-10
DE2232827A1 (de) 1973-01-18
AR194120A1 (es) 1973-06-22
DK131474B (da) 1975-07-21
NL7209345A (da) 1973-01-09
JPS5644079B1 (da) 1981-10-16
ZA724598B (en) 1973-03-28
AR194553A1 (es) 1973-07-23
IL39821A0 (en) 1972-09-28
NO137754B (no) 1978-01-09
DK131474C (da) 1975-12-08
IE36529L (en) 1973-01-05
GB1391443A (en) 1975-04-23
CA983919A (en) 1976-02-17
NL169882C (nl) 1982-09-01
PH13195A (en) 1980-01-18
NO137754C (no) 1978-04-19
AU464251B2 (en) 1975-08-21

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: GLAXO OPERATIONS UK LIMITED

PL Patent ceased