CH585709A5 - - Google Patents

Info

Publication number
CH585709A5
CH585709A5 CH1219673A CH1219673A CH585709A5 CH 585709 A5 CH585709 A5 CH 585709A5 CH 1219673 A CH1219673 A CH 1219673A CH 1219673 A CH1219673 A CH 1219673A CH 585709 A5 CH585709 A5 CH 585709A5
Authority
CH
Switzerland
Application number
CH1219673A
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1219673A priority Critical patent/CH585709A5/xx
Priority to ZA00744964A priority patent/ZA744964B/xx
Priority to US05/495,367 priority patent/US3931257A/en
Priority to AU72146/74A priority patent/AU493981B2/en
Priority to NL7411016A priority patent/NL7411016A/xx
Priority to CA207,490A priority patent/CA1030154A/en
Priority to FR7428860A priority patent/FR2241297B1/fr
Priority to JP49095601A priority patent/JPS5049243A/ja
Priority to DK451874A priority patent/DK451874A/da
Priority to DE2440606A priority patent/DE2440606A1/de
Priority to SE7410757A priority patent/SE422788B/xx
Priority to BE147837A priority patent/BE819116A/xx
Priority to GB3714174A priority patent/GB1442107A/en
Publication of CH585709A5 publication Critical patent/CH585709A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/14—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms
    • C07C403/16—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by doubly-bound oxygen atoms not being part of —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/42—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups or esterified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
CH1219673A 1973-08-24 1973-08-24 CH585709A5 (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
CH1219673A CH585709A5 (ja) 1973-08-24 1973-08-24
ZA00744964A ZA744964B (en) 1973-08-24 1974-08-02 Polyene compounds
US05/495,367 US3931257A (en) 1973-08-24 1974-08-07 Polyene compounds
AU72146/74A AU493981B2 (en) 1973-08-24 1974-08-08 Polyene compounds
NL7411016A NL7411016A (nl) 1973-08-24 1974-08-16 Polyeenverbindingen.
CA207,490A CA1030154A (en) 1973-08-24 1974-08-21 Polyene compounds
FR7428860A FR2241297B1 (ja) 1973-08-24 1974-08-22
JP49095601A JPS5049243A (ja) 1973-08-24 1974-08-22
DK451874A DK451874A (ja) 1973-08-24 1974-08-23
DE2440606A DE2440606A1 (de) 1973-08-24 1974-08-23 Polyenverbindungen
SE7410757A SE422788B (sv) 1973-08-24 1974-08-23 Forfarande for framstellning av vissa angivna 3,7-dimetyl-9-(trimetylcyklohexenyl)-nona-2,6,8-triensyralagalkylestrar
BE147837A BE819116A (fr) 1973-08-24 1974-08-23 Composes polyeniques
GB3714174A GB1442107A (ja) 1973-08-24 1974-08-23

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1219673A CH585709A5 (ja) 1973-08-24 1973-08-24
US05/495,367 US3931257A (en) 1973-08-24 1974-08-07 Polyene compounds

Publications (1)

Publication Number Publication Date
CH585709A5 true CH585709A5 (ja) 1977-03-15

Family

ID=25709815

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1219673A CH585709A5 (ja) 1973-08-24 1973-08-24

Country Status (12)

Country Link
US (1) US3931257A (ja)
JP (1) JPS5049243A (ja)
BE (1) BE819116A (ja)
CA (1) CA1030154A (ja)
CH (1) CH585709A5 (ja)
DE (1) DE2440606A1 (ja)
DK (1) DK451874A (ja)
FR (1) FR2241297B1 (ja)
GB (1) GB1442107A (ja)
NL (1) NL7411016A (ja)
SE (1) SE422788B (ja)
ZA (1) ZA744964B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054589A (en) * 1974-09-26 1977-10-18 Hoffmann-La Roche Inc. Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene esters
US4107190A (en) * 1974-09-26 1978-08-15 Hoffmann-La Roche Inc. Novel compounds of 9-phenyl-3,7-dimethyl-2,4,6,8-nonatetraenamide
US4187247A (en) * 1974-09-26 1980-02-05 Hoffmann-La Roche Inc. 9-Substituted phenyl-3,7-dimethyl-nona 2,4,6,8-tetraene compounds
JPS51125234A (en) * 1974-09-26 1976-11-01 Hoffmann La Roche Preparation of polyene compounds
US4108880A (en) * 1975-11-03 1978-08-22 Johnson & Johnson Esters of retinoic acid
US4190594A (en) * 1975-11-03 1980-02-26 Johnson & Johnson Retinoic acid derivatives
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
LU77254A1 (ja) * 1977-05-04 1979-01-18
US4199587A (en) * 1977-08-10 1980-04-22 Eisai Co., Ltd. Method of treating hypertension with polyprenyl alcohol ester
US4533554A (en) * 1979-05-18 1985-08-06 Takeda Chemical Industries, Ltd. Quinone derivatives and use
JPS5640651A (en) * 1979-09-12 1981-04-16 Takeda Chem Ind Ltd Quinone compound and its preparation
US4439614A (en) * 1982-09-22 1984-03-27 Sri International 5,6-Methano-5,6-dihydroretinoids
US4642318A (en) * 1982-11-17 1987-02-10 Klaus Wolff Method for decreasing radiation load in PUVA therapy
US4722939A (en) * 1983-07-29 1988-02-02 Usv Pharmaceutical Corporation Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis
US4523042A (en) * 1983-07-29 1985-06-11 Usv Pharmaceutical Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis
US4648996A (en) * 1984-07-27 1987-03-10 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4894480A (en) * 1984-07-27 1990-01-16 Hoffmann-La Roche Inc. Phenyl substituted-2,4,6,8-nonatetraenoic acid
US4843096A (en) * 1985-06-26 1989-06-27 Stiefel Laboratories, Inc. Treatment of acne
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
US5070108A (en) * 1990-10-12 1991-12-03 Trustees Of The University Of Pennsylvania Methods of treating osteoporosis, increasing bone mineral content and preventing the occurrence of compression fractures in a mammal
US6150421A (en) * 1995-01-11 2000-11-21 Cornell Research Foundation, Inc. Treatment of estrogen-receptor positive breast cancer and estrogen-receptor negative breast cancer with retinoid with CH2 OH at the side chain terminal position
US5786391A (en) * 1995-01-11 1998-07-28 Cornell Research Foundation, Inc. Regulating gene expression using retinoids with Ch2 OH or related groups at the side chain terminal position

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2529498A (en) * 1946-04-12 1950-11-14 Hoffmann La Roche Process for the manufacture of pentaenes
DE1149353B (de) * 1960-08-03 1963-05-30 Bayer Ag Verfahren zur Herstellung von 6-[2', 6', 6'-Trimethylcyclohexen-(1')-yl]-4-methylhexadien-(3, 5)-in-(1) (íÀC-KohlenwasserstoffíÂ)
US3876673A (en) * 1970-08-05 1975-04-08 Rhone Poulenc Sa Intermediates useful in the synthesis of vitamin a
CA939369A (en) * 1970-10-13 1974-01-01 John A. Findlay Process for preparing hydrocarbon acid esters
US3781313A (en) * 1971-01-20 1973-12-25 Rhone Poulenc Sa Sulfone intermediates for the synthesis of vitamin a

Also Published As

Publication number Publication date
SE422788B (sv) 1982-03-29
AU7214674A (en) 1976-02-12
FR2241297B1 (ja) 1978-11-10
JPS5049243A (ja) 1975-05-01
ZA744964B (en) 1975-08-27
DK451874A (ja) 1975-04-28
FR2241297A1 (ja) 1975-03-21
NL7411016A (nl) 1975-02-26
DE2440606A1 (de) 1975-03-06
GB1442107A (ja) 1976-07-07
CA1030154A (en) 1978-04-25
SE7410757L (ja) 1975-02-25
BE819116A (fr) 1975-02-24
US3931257A (en) 1976-01-06

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Legal Events

Date Code Title Description
PL Patent ceased