CH553792A - Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid. - Google Patents

Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid.

Info

Publication number
CH553792A
CH553792A CH832571A CH832571A CH553792A CH 553792 A CH553792 A CH 553792A CH 832571 A CH832571 A CH 832571A CH 832571 A CH832571 A CH 832571A CH 553792 A CH553792 A CH 553792A
Authority
CH
Switzerland
Prior art keywords
aminoaethyl
diaethyl
monohydrochloride
benzodiazepine
fluorophenyl
Prior art date
Application number
CH832571A
Other languages
German (de)
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES397552A priority Critical patent/ES397552A1/es
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH832571A priority patent/CH553792A/xx
Priority to FI713268A priority patent/FI51352C/fi
Priority to NO4214/71A priority patent/NO133714C/no
Priority to DK561771AA priority patent/DK127506B/da
Priority to SE7114654A priority patent/SE388856B/xx
Priority to HUHO1433A priority patent/HU170152B/hu
Priority to DE2157112A priority patent/DE2157112C3/de
Priority to AT996671A priority patent/AT313281B/de
Priority to PL1971151697A priority patent/PL81437B1/pl
Priority to GB5436871A priority patent/GB1331823A/en
Priority to ZA717880A priority patent/ZA717880B/xx
Priority to CY868A priority patent/CY868A/xx
Priority to CA128,336A priority patent/CA945989A/en
Priority to IE1489/71A priority patent/IE35846B1/xx
Priority to BG019094A priority patent/BG19173A3/xx
Priority to IL38252A priority patent/IL38252A/xx
Priority to NL7116376A priority patent/NL7116376A/xx
Priority to SU1959119A priority patent/SU475776A3/ru
Priority to SU1721027A priority patent/SU444369A1/ru
Priority to JP46096838A priority patent/JPS5230568B1/ja
Priority to RO68930A priority patent/RO59000A/ro
Priority to RO75458A priority patent/RO58965A/ro
Priority to MX131834A priority patent/MX149567A/es
Priority to BR8123/71A priority patent/BR7108123D0/pt
Priority to PH13088A priority patent/PH13530A/en
Priority to DD159994A priority patent/DD98679A5/xx
Priority to CS913171A priority patent/CS155105B2/cs
Priority to CS752472A priority patent/CS155106B2/cs
Priority to BE777897A priority patent/BE777897A/fr
Priority to FR7200802A priority patent/FR2140371B1/fr
Priority to LU65469A priority patent/LU65469A1/xx
Publication of CH553792A publication Critical patent/CH553792A/xx
Priority to MY115/74A priority patent/MY7400115A/xx
Priority to SE7513088A priority patent/SE7513088L/xx
Priority to KE2652*UA priority patent/KE2652A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH832571A 1971-06-08 1971-06-08 Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid. CH553792A (de)

Priority Applications (35)

Application Number Priority Date Filing Date Title
ES397552A ES397552A1 (es) 1971-06-08 1971-02-01 Un procedimiento para la preparacion de monoclorhidrado de 7 - cloro - 1 - (2-dietilaminoetil) - 5 - (2 - fluorofenil) 1,3-dihidro - 2h - 1,4 - benzodiacepin - 2-ona.
CH832571A CH553792A (de) 1971-06-08 1971-06-08 Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid.
FI713268A FI51352C (fi) 1971-06-08 1971-11-15 Menetelmä terapeuttisesti käytettävän 7-kloori-1-(2-dietyyliaminoetyyl i)-5-(2-fluorifenyyli)-1,3-dihydro-2H-1,4-bentsodiatsepin-2-oni-monohy drokloridin valmistamiseksi.
NO4214/71A NO133714C (fr) 1971-06-08 1971-11-15
DK561771AA DK127506B (da) 1971-06-08 1971-11-16 Analogifremgangsmåde til fremstilling af 7-chlor-1-(2-diethylaminoethyl)-5-(2-fluorphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on-monohydrochlorid.
SE7114654A SE388856B (sv) 1971-06-08 1971-11-16 Sett att framstella 7-klor-1-(2-dietylaminoetyl)-5-(2-fluorfenyl)-1,3-dihydro-2h-1,4-bensodiazepin-2-on-monohydroklorid
DE2157112A DE2157112C3 (de) 1971-06-08 1971-11-17 Benzodiazepin-Derivat
HUHO1433A HU170152B (fr) 1971-06-08 1971-11-17
AT996671A AT313281B (de) 1971-06-08 1971-11-18 Verfahren zur Herstellung des neuen 7-Chlor-1-(2-diäthyl-amino-äthyl)-5-(2-fluorphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on-monohydrochlorids
PL1971151697A PL81437B1 (fr) 1971-06-08 1971-11-22
GB5436871A GB1331823A (en) 1971-06-08 1971-11-23 Benzodiazepine derivative
ZA717880A ZA717880B (en) 1971-06-08 1971-11-23 Benzodiazepine derivative
CY868A CY868A (en) 1971-06-08 1971-11-23 A benzodiazepine derivative
CA128,336A CA945989A (en) 1971-06-08 1971-11-23 Benzodiazepine derivative
IE1489/71A IE35846B1 (en) 1971-06-08 1971-11-24 A benzodiazepine derivative
BG019094A BG19173A3 (bg) 1971-06-08 1971-11-25 Метод за получаване на бензодиазепиново производно
NL7116376A NL7116376A (fr) 1971-06-08 1971-11-29
IL38252A IL38252A (en) 1971-06-08 1971-11-29 7-chloro-1-(diethylaminoethyl)-5-(2-fluorophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-one monohydrochloride,its preparation and pharmaceutical compositions containing it
SU1959119A SU475776A3 (ru) 1971-06-08 1971-11-29 Способ получени 7-хлор-1-(2-диэтиламиноэтил)-5-(2-фторфенил)-1,3-дигидро-2н-1,4-бензодиазепин-2-он-моногидрохлорида
SU1721027A SU444369A1 (ru) 1971-11-29 Способ получени 7-хлор-1-(2-диэтиламиноэтил)-5-(2-фторфенил)1,3-дигидро-2н-1,4-бензодиазепин2-он-моногидрохлорида
JP46096838A JPS5230568B1 (fr) 1971-06-08 1971-12-02
RO68930A RO59000A (fr) 1971-06-08 1971-12-02
RO75458A RO58965A (fr) 1971-06-08 1971-12-02
MX131834A MX149567A (es) 1971-06-08 1971-12-04 Procedimiento para la preparacion de monoclorhidrato de 7-cloro-1-(2-dietilaminoetil)-5-(2-fluorofenil)-1,3-dihidro-2h-1,4-benzodiacepin-2-ona
BR8123/71A BR7108123D0 (pt) 1971-06-08 1971-12-08 Derivados de benzodiazepina
PH13088A PH13530A (en) 1971-06-08 1971-12-09 Benzodiazepine derivative
DD159994A DD98679A5 (fr) 1971-06-08 1971-12-29
CS913171A CS155105B2 (fr) 1971-06-08 1971-12-30
CS752472A CS155106B2 (fr) 1971-06-08 1971-12-30
BE777897A BE777897A (fr) 1971-06-08 1972-01-11 Derives de benzodiazepine
FR7200802A FR2140371B1 (fr) 1971-06-08 1972-01-11
LU65469A LU65469A1 (fr) 1971-06-08 1972-06-06
MY115/74A MY7400115A (en) 1971-06-08 1974-12-30 A benzodiazepine derivative
SE7513088A SE7513088L (sv) 1971-06-08 1975-11-20 Bensodiazepiner
KE2652*UA KE2652A (en) 1971-06-08 1976-07-21 A benzodiazepine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH832571A CH553792A (de) 1971-06-08 1971-06-08 Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid.

Publications (1)

Publication Number Publication Date
CH553792A true CH553792A (de) 1974-09-13

Family

ID=4338591

Family Applications (1)

Application Number Title Priority Date Filing Date
CH832571A CH553792A (de) 1971-06-08 1971-06-08 Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid.

Country Status (31)

Country Link
JP (1) JPS5230568B1 (fr)
AT (1) AT313281B (fr)
BE (1) BE777897A (fr)
BG (1) BG19173A3 (fr)
BR (1) BR7108123D0 (fr)
CA (1) CA945989A (fr)
CH (1) CH553792A (fr)
CS (2) CS155106B2 (fr)
CY (1) CY868A (fr)
DD (1) DD98679A5 (fr)
DE (1) DE2157112C3 (fr)
DK (1) DK127506B (fr)
ES (1) ES397552A1 (fr)
FI (1) FI51352C (fr)
FR (1) FR2140371B1 (fr)
GB (1) GB1331823A (fr)
HU (1) HU170152B (fr)
IE (1) IE35846B1 (fr)
IL (1) IL38252A (fr)
KE (1) KE2652A (fr)
LU (1) LU65469A1 (fr)
MX (1) MX149567A (fr)
MY (1) MY7400115A (fr)
NL (1) NL7116376A (fr)
NO (1) NO133714C (fr)
PH (1) PH13530A (fr)
PL (1) PL81437B1 (fr)
RO (2) RO59000A (fr)
SE (2) SE388856B (fr)
SU (1) SU475776A3 (fr)
ZA (1) ZA717880B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1199304A1 (fr) * 1997-03-05 2002-04-24 Takeda Chemical Industries, Ltd. Composés bicycliques et composition pharmaceutique contenant un composé tricyclique pour le traitement ou la prévention de troubles de sommeil

Also Published As

Publication number Publication date
CA945989A (en) 1974-04-23
DK127506B (da) 1973-11-19
ZA717880B (en) 1973-01-31
IL38252A (en) 1974-11-29
BG19173A3 (bg) 1975-04-30
SU475776A3 (ru) 1975-06-30
SE7513088L (sv) 1975-11-20
FR2140371B1 (fr) 1975-06-13
SU444369A3 (ru) 1974-09-25
IE35846B1 (en) 1976-06-09
ES397552A1 (es) 1975-03-16
MY7400115A (en) 1974-12-31
CY868A (en) 1976-12-17
DE2157112B2 (de) 1980-10-09
NO133714B (fr) 1976-03-08
LU65469A1 (fr) 1973-12-14
RO59000A (fr) 1975-12-15
HU170152B (fr) 1977-04-28
IL38252A0 (en) 1972-01-27
JPS5230568B1 (fr) 1977-08-09
AT313281B (de) 1974-02-11
DE2157112A1 (de) 1972-12-28
SE388856B (sv) 1976-10-18
MX149567A (es) 1983-11-25
NL7116376A (fr) 1972-12-12
NO133714C (fr) 1976-06-16
BE777897A (fr) 1972-07-11
FR2140371A1 (fr) 1973-01-19
DE2157112C3 (de) 1981-09-03
RO58965A (fr) 1975-09-15
FI51352C (fi) 1976-12-10
IE35846L (en) 1972-12-08
CS155106B2 (fr) 1974-05-30
DD98679A5 (fr) 1973-07-05
CS155105B2 (fr) 1974-05-30
PH13530A (en) 1980-06-19
GB1331823A (en) 1973-09-26
KE2652A (en) 1976-08-13
FI51352B (fr) 1976-08-31
PL81437B1 (fr) 1975-08-30
BR7108123D0 (pt) 1973-07-03

Similar Documents

Publication Publication Date Title
CH550185A (de) Verfahren zur herstellung von benzodiazepin-derivaten.
AT296312B (de) Verfahren zur Herstellung von 2,3-Dihydro-1H-1,4-benzodiazepinen bzw. von Salzen hievon
CH553792A (de) Verfahren zur herstellung von 7-chlor-1-(2-diaethyl-aminoaethyl)-5-(2-fluorphenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-on-monohydrochlorid.
CH549034A (de) Verfahren zur herstellung von neuen benzodiazepin-derivaten.
CH554361A (de) Verfahren zur herstellung von benzodiazepin-derivaten.
CH534169A (de) Verfahren zur Herstellung von neuen Dihydro-1,4-Benzodiazepinen
CH549035A (de) Verfahren zur herstellung von neuen benzodiazepin-derivaten.
CH557357A (de) Verfahren zur herstellung von benzodiazepinderivaten.
CH523266A (de) Verfahren zur Herstellung von 1-Alkyl-5-phenyl-1,2,4,5-tetrahydro-3H-1,4-benzodiazepinen
CH554349A (de) Verfahren zur herstellung von optisch aktiven 1,3-dihydro-2h-1,4-benzodiazepin-2-onen.
CH549030A (de) Verfahren zur herstellung von 1,2-dihydro-3h-1,4-benzodiazepinen.
CH546730A (de) Verfahren zur herstellung von n,n'-bis-trifluormethyl-tetrafluoraethylendiamin.
AT316558B (de) Verfahren zur Herstellung von 7-Chlor-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-on
CH556852A (de) Verfahren zur herstellung von neuen 1,4-benzodiazepinen.
CH548405A (de) Verfahren zur herstellung von benzodiazepinderivaten.
CH474528A (de) Verfahren zur Herstellung von 1-Methyl-7-halogen-2, 3-dihydro-5-phenyl-1,4-benzodiazepinen
AT324343B (de) Verfahren zur herstellung von 7-chlor-1,2-dihydro-5-phenyl-1,4-benzodiazepin-2-onen
CH555348A (de) Verfahren zur herstellung von benzodiazepinderivaten.
CH510034A (de) Verfahren zur Herstellung von 1,4-Benzodiazepinen
ATA905775A (de) Verfahren zur herstellung von 7-chlor-1-(2- diaethylamino-aethyl)-5-(o-fluorpenyl)-1,3- dihydro-2h-1,4-benzodiazepin-2-on
AT312621B (de) Verfahren zur Herstellung von neuen 2-Alkylmercapto-5-phenyl-4H-3,5-dihydro-1,5-benzodiazepin-4-onen
AT311356B (de) Verfahren zur Herstellung von 1,3,4,5-Tetrahydro-2H-1,4-benzodiazepin-2-on-Derivaten
AT306023B (de) Verfahren zur Herstellung von 2,3-Dihydro-1H-1,4-benzodiazepinen bzw. von Salzen hievon
AT305285B (de) Verfahren zur Herstellung von 1,4-Benzodiazepinen
CH557359A (de) Verfahren zur herstellung von derivaten des 5-phenyl3h-1,4-benzodiazepins.

Legal Events

Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased