CH525224A - Verfahren zur Herstellung von Indolverbindungen und deren Verwendung - Google Patents

Verfahren zur Herstellung von Indolverbindungen und deren Verwendung

Info

Publication number
CH525224A
CH525224A CH647268A CH647268A CH525224A CH 525224 A CH525224 A CH 525224A CH 647268 A CH647268 A CH 647268A CH 647268 A CH647268 A CH 647268A CH 525224 A CH525224 A CH 525224A
Authority
CH
Switzerland
Prior art keywords
preparation
indole compounds
indole
compounds
Prior art date
Application number
CH647268A
Other languages
English (en)
Inventor
Archer Sydney
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of CH525224A publication Critical patent/CH525224A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
CH647268A 1967-05-01 1968-04-30 Verfahren zur Herstellung von Indolverbindungen und deren Verwendung CH525224A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63489967A 1967-05-01 1967-05-01
CA17589 1968-04-16
US85850069A 1969-09-16 1969-09-16

Publications (1)

Publication Number Publication Date
CH525224A true CH525224A (de) 1972-07-15

Family

ID=27160266

Family Applications (1)

Application Number Title Priority Date Filing Date
CH647268A CH525224A (de) 1967-05-01 1968-04-30 Verfahren zur Herstellung von Indolverbindungen und deren Verwendung

Country Status (5)

Country Link
US (2) US3639414A (de)
CH (1) CH525224A (de)
DE (1) DE1770305A1 (de)
FR (1) FR8340M (de)
GB (1) GB1189064A (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
US3888861A (en) * 1974-01-07 1975-06-10 Colgate Palmolive Co 3-(2-(4-substituted-piperazin-1-yl)ethyl)indoles
US3936464A (en) * 1974-10-25 1976-02-03 American Cyanamid Company 1-Acyl-3-[2-(4-phenyl-1-piperidinyl)ethyl]indolines
US4046900A (en) * 1975-08-08 1977-09-06 American Hoechst Corporation Benzoylpiperidylalkylindoles
DE2708913A1 (de) * 1976-03-04 1977-09-08 Hoechst Ag Benzoylpiperidyalkyl-indole und verwandte verbindungen
US4145422A (en) * 1977-09-06 1979-03-20 Abbott Laboratories Aminomethylene oxindoles
EP0007399B1 (de) * 1978-06-24 1982-01-20 MERCK PATENT GmbH Indolalkylamine, diese enthaltende pharmazeutische Zubereitungen und Verfahren zu ihrer Herstellung
US4328345A (en) * 1978-10-02 1982-05-04 Schering Corporation Pyridyl substituted indoles
DE3236243A1 (de) * 1982-09-30 1984-04-05 Merck Patent Gmbh, 6100 Darmstadt Schwefelhaltige indolderivate
DE3308668A1 (de) * 1983-03-11 1984-09-13 Merck Patent Gmbh, 6100 Darmstadt Indolderivate
DE3342632A1 (de) * 1983-11-25 1985-06-05 Merck Patent Gmbh, 6100 Darmstadt Indolderivate
US5256673A (en) * 1983-11-25 1993-10-26 Merck Patent Gesellschaft Mit Beschrankter Haftung Indole-3-yl-A-tetrahydropyridyl or piperidyl compounds
DE3421641A1 (de) * 1984-06-09 1985-12-12 Merck Patent Gmbh, 6100 Darmstadt Indolderivate
EP0187122A3 (de) * 1985-01-03 1987-12-16 Ciba-Geigy Ag 1,3,4-Trisubstituierte Azacycloalkane bzw. Azacycloalkene
EP0187619A3 (de) * 1985-01-03 1987-08-26 Ciba-Geigy Ag 1,3-disubstituierte Tetrahydropyridine
US5382661A (en) * 1985-09-12 1995-01-17 The Upjohn Company Pyrazinylpiperazinyl steroids
GB8531612D0 (en) * 1985-12-23 1986-02-05 Beecham Wuelfing Gmbh & Co Kg Compounds
US5120843A (en) * 1987-04-27 1992-06-09 Upjohn Pharmaceutically active amines
US5142052A (en) * 1988-04-22 1992-08-25 Laboratoires Syntex Cationic effect-driven carbinol/amine reaction
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
US5563142A (en) * 1989-12-28 1996-10-08 The Upjohn Company Diaromatic substituted compounds as anti-HIV-1 agents
FR2672052B1 (fr) * 1991-01-28 1995-05-24 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
CA2043709C (en) * 1990-06-29 2002-01-22 David W. Smith Antimigraine alkoxypyrimidine derivatives
US5077293A (en) * 1990-06-29 1991-12-31 Bristol-Myers Squibb Co. 1-indolyalkyl-4-(alkoxypyrimidinyl)piperazines
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
US5599930A (en) * 1991-07-03 1997-02-04 The Upjohn Company Substituted indoles as anti-AIDS pharmaceuticals
CA2084531A1 (en) 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
ES2079323B1 (es) * 1994-06-21 1996-10-16 Vita Invest Sa Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
US9714232B2 (en) 2013-12-20 2017-07-25 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use thereof
CN106243088B (zh) 2015-06-03 2019-01-04 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途

Also Published As

Publication number Publication date
US3562278A (en) 1971-02-09
DE1770305A1 (de) 1971-10-21
FR8340M (de) 1970-12-21
GB1189064A (en) 1970-04-22
US3639414A (en) 1972-02-01

Similar Documents

Publication Publication Date Title
CH525224A (de) Verfahren zur Herstellung von Indolverbindungen und deren Verwendung
CH516519A (de) Verfahren zur Herstellung von Asparaginsäurederivaten und deren Verwendung
AT284816B (de) Verfahren zur Herstellung von neuen Amino-monohalogenphenyläthanolaminen und von deren Salzen
CH492685A (de) Verfahren zur Herstellung von Olefinsulfonaten und deren Verwendung
AT286992B (de) Verfahren zur Herstellung von Pyrimidinderivaten und von deren Salzen
CH507945A (de) Verfahren zur Herstellung von 1,2,3,4-Tetrahydrocarbazolderivaten und deren Verwendung
CH534175A (de) Verfahren zur Herstellung von heterocyclischen Hydroxyalkylaminoxyden und deren Verwendung
CH530396A (de) Verfahren zur Herstellung von N-Phenylindolinderivaten und deren Verwendung
CH539009A (de) Verfahren zur Herstellung von Hydroxyverbindungen und deren Verwendung
CH554896A (de) Verfahren zur herstellung von p-nitrobenzyl-desacetoxycephalosporinestern und deren verwendung.
CH456580A (de) Verfahren zur Herstellung von Nitroalkyladamantanen und deren Verwendung
CH513947A (de) Verfahren zur Herstellung von Farbstoffen und Verwendung derselben
CH513920A (de) Verfahren zur Herstellung von 7-Aminocephalosporansäure und deren Derivate
CH521943A (de) Verfahren zur Herstellung von Aminophenolen und deren Verwendung
CH524623A (de) Verfahren zur Herstellung von Triazaadamantan-Derivaten und deren Verwendung
CH532559A (de) Verfahren zur Herstellung von Sulfamylbenzoesäure-Derivaten und deren Verwendung
AT286305B (de) Verfahren zur herstellung von neuen hydrindensulfonylaminoverbindungen und von deren salzen
CH510710A (de) Verfahren zur Herstellung von Polyoxamiden und deren Verwendung
AT289123B (de) Verfahren zur Herstellung von Pyrazinamidderivaten und von deren Salzen
CH541608A (de) Verfahren zur Herstellung von Nitrodiphenylaminen und deren Verwendung
CH485666A (de) Verfahren zur Herstellung von Niederalkyl-a-carboalkoxy-B-(3-niederalkyl-4-niederalkoxy-anilino)--acrylaten und deren Verwendung zur Herstellung von entsprechenden Chinolaten
CH460001A (de) Verfahren zur Herstellung von Sulfoxid-Zinnkomplexverbindungen und deren Verwendung
CH484149A (de) Verfahren zur Herstellung von Imidazolidonen und deren Verwendung
CH522578A (de) Verfahren zur Herstellung von Ketonen und deren Verwendung
CH481881A (de) Verfahren zur Herstellung von Fluoracetyla minotrichlormethylmethan-Derivaten und deren Verwendung

Legal Events

Date Code Title Description
PL Patent ceased