CH520684A - Process for the preparation of benzimidazole carbamates - Google Patents
Process for the preparation of benzimidazole carbamatesInfo
- Publication number
- CH520684A CH520684A CH809370A CH809370A CH520684A CH 520684 A CH520684 A CH 520684A CH 809370 A CH809370 A CH 809370A CH 809370 A CH809370 A CH 809370A CH 520684 A CH520684 A CH 520684A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- benzimidazole carbamates
- carbamates
- benzimidazole
- Prior art date
Links
- BHFLSZOGGDDWQM-UHFFFAOYSA-N 1h-benzimidazole;carbamic acid Chemical class NC(O)=O.C1=CC=C2NC=NC2=C1 BHFLSZOGGDDWQM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83524669A | 1969-06-20 | 1969-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH520684A true CH520684A (en) | 1972-03-31 |
Family
ID=25269027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH809370A CH520684A (en) | 1969-06-20 | 1970-05-29 | Process for the preparation of benzimidazole carbamates |
Country Status (20)
Country | Link |
---|---|
US (1) | US3657267A (en) |
JP (1) | JPS501272B1 (en) |
AT (2) | AT307798B (en) |
BE (1) | BE752089A (en) |
CH (1) | CH520684A (en) |
CS (1) | CS201522B2 (en) |
DK (2) | DK134602B (en) |
ES (1) | ES380579A1 (en) |
FI (1) | FI52719C (en) |
FR (1) | FR2052988B1 (en) |
GB (1) | GB1307306A (en) |
HK (1) | HK77976A (en) |
IL (1) | IL34746A (en) |
IT (1) | IT1035027B (en) |
MY (1) | MY7300477A (en) |
NL (1) | NL147139B (en) |
PL (1) | PL72724B1 (en) |
SE (1) | SE366045B (en) |
YU (1) | YU34195B (en) |
ZA (1) | ZA704191B (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2201208A1 (en) * | 1972-01-12 | 1973-08-02 | Basf Ag | PROCESS FOR MANUFACTURING AROMATIC KETONES |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
US4258198A (en) * | 1973-05-29 | 1981-03-24 | Smithkline Corporation | 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles |
US3969526A (en) * | 1973-05-29 | 1976-07-13 | Smithkline Corporation | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles |
DE2443297A1 (en) * | 1974-09-10 | 1976-03-18 | Hoechst Ag | ANTHELMINTHICALLY ACTIVE BASIC SUBSTITUTED 2-CARBALKOXY-AMINO-BENZIMIDAZOLYL-5 (6) -PHENYL ETHERS AND KETONES AND THE PROCESS FOR THEIR PRODUCTION |
US4026936A (en) * | 1975-08-07 | 1977-05-31 | Hoffmann-La Roche Inc. | Anthelmintic pyridine and thiazole substituted benzimidazole carbamates |
US4031234A (en) * | 1975-08-18 | 1977-06-21 | Syntex (U.S.A.) Inc. | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4032536A (en) * | 1976-07-22 | 1977-06-28 | Janssen Pharmaceutica N.V. | (1h-benzimidazol-2-yl)carbamates |
IT1076022B (en) * | 1977-04-20 | 1985-04-22 | Montedison Spa | ANTIELMINTIC BENZIMIDAZOLCARBAMMATES |
JPS5535611A (en) * | 1978-08-31 | 1980-03-12 | Matsushita Electric Works Ltd | Instrument with mouth washing instrument |
US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
US4435418A (en) | 1982-12-13 | 1984-03-06 | Smithkline Beckman Corporation | 5-Phenylethenylbenzimidazoles |
US4438135A (en) | 1983-01-07 | 1984-03-20 | Smithkline Beckman Corporation | 1-(3,4-Bis-(3-(lower alkoxycarbonyl)-2-thioureido)-phenyl-1-phenylthylenes |
NZ232785A (en) * | 1989-03-15 | 1991-03-26 | Janssen Pharmaceutica Nv | 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions |
US5256681A (en) * | 1989-03-15 | 1993-10-26 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates |
WO1990010630A1 (en) * | 1989-03-15 | 1990-09-20 | Janssen Pharmaceutica N.V. | [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates |
US5278181A (en) * | 1992-05-12 | 1994-01-11 | Board Of Regents Acting On Behalf Of The University Of Michigan | Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics |
TW200740838A (en) * | 2005-07-28 | 2007-11-01 | Intervet Int Bv | Novel benzimidazole (thio)carbamates with antiparasitic activity and the synthesis thereof |
WO2007144362A1 (en) | 2006-06-14 | 2007-12-21 | Intervet International B.V. | A suspension comprising benzimidazole carbamate and a polysorbate |
US20130197527A1 (en) * | 2006-06-12 | 2013-08-01 | Smith & Nephew, Inc. | Systems, methods and devices for tibial resection |
MX340846B (en) | 2012-01-27 | 2016-07-28 | Rhein Siegfried Sa De Cv | Improved nitazoxanide composition and preparation method thereof. |
BR112015006861B1 (en) | 2012-09-27 | 2021-10-13 | Siegfried Rhein S.A. De C.V. | SYNERGIC PHARMACEUTICAL COMPOSITION AND PROCESS TO PREPARE SUCH COMPOSITION |
CN108884054B (en) * | 2015-11-30 | 2022-08-02 | 儿童医学中心公司 | Compounds for the treatment of proliferative diseases |
ES2962526T3 (en) | 2017-06-22 | 2024-03-19 | Cipla Ltd | PAR-4 secretagogues for cancer treatment |
CN109467512B (en) * | 2018-12-18 | 2021-06-08 | 苏州开元民生科技股份有限公司 | Synthetic method of 3, 4-diamino-benzophenone |
CN113979949A (en) * | 2021-12-17 | 2022-01-28 | 山东国邦药业有限公司 | Preparation method of fluorobenzene imidazole |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1111957A (en) * | 1966-05-20 | 1968-05-01 | Smith Kline French Lab | Improvements in or relating to anthelmintic compositions |
-
1969
- 1969-06-20 US US835246A patent/US3657267A/en not_active Expired - Lifetime
-
1970
- 1970-05-29 GB GB2604470A patent/GB1307306A/en not_active Expired
- 1970-05-29 CH CH809370A patent/CH520684A/en not_active IP Right Cessation
- 1970-06-08 FR FR707021022A patent/FR2052988B1/fr not_active Expired
- 1970-06-09 ES ES380579A patent/ES380579A1/en not_active Expired
- 1970-06-16 PL PL1970141321A patent/PL72724B1/pl unknown
- 1970-06-17 SE SE08385/70A patent/SE366045B/xx unknown
- 1970-06-17 BE BE752089D patent/BE752089A/en not_active IP Right Cessation
- 1970-06-18 FI FI701720A patent/FI52719C/en active
- 1970-06-18 IL IL34746A patent/IL34746A/en unknown
- 1970-06-18 AT AT549770A patent/AT307798B/en not_active IP Right Cessation
- 1970-06-18 AT AT825571A patent/AT302358B/en not_active IP Right Cessation
- 1970-06-18 YU YU1544/70A patent/YU34195B/en unknown
- 1970-06-18 IT IT51551/70A patent/IT1035027B/en active
- 1970-06-19 ZA ZA704191A patent/ZA704191B/en unknown
- 1970-06-19 NL NL707009024A patent/NL147139B/en not_active IP Right Cessation
- 1970-06-19 CS CS704330A patent/CS201522B2/en unknown
- 1970-06-19 JP JP45053435A patent/JPS501272B1/ja active Pending
- 1970-06-22 DK DK321770AA patent/DK134602B/en not_active IP Right Cessation
-
1973
- 1973-12-30 MY MY477/73A patent/MY7300477A/en unknown
-
1975
- 1975-12-19 DK DK580275A patent/DK580275A/en unknown
-
1976
- 1976-12-09 HK HK779/76*UA patent/HK77976A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB1307306A (en) | 1973-02-21 |
NL147139B (en) | 1975-09-15 |
FR2052988B1 (en) | 1973-08-10 |
CS201522B2 (en) | 1980-11-28 |
YU154470A (en) | 1978-09-18 |
MY7300477A (en) | 1973-12-31 |
HK77976A (en) | 1976-12-17 |
AT307798B (en) | 1973-06-12 |
YU34195B (en) | 1979-02-28 |
ES380579A1 (en) | 1973-04-01 |
FR2052988A1 (en) | 1971-04-16 |
IT1035027B (en) | 1979-10-20 |
ZA704191B (en) | 1972-02-23 |
FI52719C (en) | 1977-11-10 |
JPS501272B1 (en) | 1975-01-16 |
AT302358B (en) | 1972-10-10 |
US3657267A (en) | 1972-04-18 |
IL34746A0 (en) | 1970-08-19 |
DK580275A (en) | 1975-12-19 |
IL34746A (en) | 1973-01-30 |
NL7009024A (en) | 1970-12-22 |
SE366045B (en) | 1974-04-08 |
DE2029637A1 (en) | 1971-02-18 |
PL72724B1 (en) | 1974-08-30 |
DK134602B (en) | 1976-12-06 |
DK134602C (en) | 1977-06-27 |
DE2029637B2 (en) | 1976-09-23 |
FI52719B (en) | 1977-08-01 |
BE752089A (en) | 1970-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |