CH487880A - Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate - Google Patents

Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate

Info

Publication number
CH487880A
CH487880A CH878164A CH878164A CH487880A CH 487880 A CH487880 A CH 487880A CH 878164 A CH878164 A CH 878164A CH 878164 A CH878164 A CH 878164A CH 487880 A CH487880 A CH 487880A
Authority
CH
Switzerland
Prior art keywords
secosteroids
androstane
oxo
derivatives
new
Prior art date
Application number
CH878164A
Other languages
English (en)
Inventor
Georg Dr Anner
Charles Dr Meystre
Jaroslav Dr Kalvoda
Hellmut Dr Ueberwasser
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Priority to CH878164A priority Critical patent/CH487880A/de
Priority to CH1147564A priority patent/CH505809A/de
Priority to CH381465A priority patent/CH461478A/de
Priority to DE19651518658 priority patent/DE1518658A1/de
Priority to US467691A priority patent/US3431191A/en
Priority to FR22672A priority patent/FR1463849A/fr
Priority to NL6508559A priority patent/NL6508559A/xx
Priority to GB28298/65A priority patent/GB1065432A/en
Publication of CH487880A publication Critical patent/CH487880A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29—Saturated compounds containing keto groups bound to rings
    • C07C49/313—Saturated compounds containing keto groups bound to rings polycyclic
    • C07C49/323—Saturated compounds containing keto groups bound to rings polycyclic having keto groups bound to condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C07C49/643—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
CH878164A 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate CH487880A (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden
DE19651518658 DE1518658A1 (de) 1964-07-03 1965-06-26 Neue 5,10-Seco-steroide
US467691A US3431191A (en) 1964-07-03 1965-06-28 Process for producing 5,10-seco-steroids
FR22672A FR1463849A (fr) 1964-07-03 1965-06-29 Nouveaux 5, 10-séco-stéroïdes et procédé pour leur préparation
NL6508559A NL6508559A (de) 1964-07-03 1965-07-02
GB28298/65A GB1065432A (en) 1964-07-03 1965-07-05 New 5,10-seco-steroids and process for their manufacture

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden
CH705165 1965-05-20

Publications (1)

Publication Number Publication Date
CH487880A true CH487880A (de) 1970-03-31

Family

ID=27428676

Family Applications (3)

Application Number Title Priority Date Filing Date
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden

Country Status (5)

Country Link
US (1) US3431191A (de)
CH (3) CH487880A (de)
DE (1) DE1518658A1 (de)
GB (1) GB1065432A (de)
NL (1) NL6508559A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979458A (en) * 1967-12-04 1976-09-07 Syntex Corporation Production of unsaturated carbocyclic ketones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662854A (en) * 1950-10-12 1953-12-15 Ciba Pharm Prod Inc Photochemical preparation of 17, 20-hydroxy-ketones of the pregnane series
NL122642C (de) * 1963-02-27

Also Published As

Publication number Publication date
NL6508559A (de) 1966-01-04
CH505809A (de) 1971-04-15
DE1518658A1 (de) 1969-08-14
US3431191A (en) 1969-03-04
CH461478A (de) 1968-08-31
GB1065432A (en) 1967-04-12

Similar Documents

Publication Publication Date Title
AT265539B (de) Verfahren zur Herstellung neuer Steroid- [17α,16α-d]-oxazoline
AT292929B (de) Verfahren zur Herstellung von 17α-Monoestern von 11β,17α,21-Trihydroxysteroiden
CH428429A (de) Diazotypisches Lichtpausmaterial und Verfahren zu dessen Herstellung
CH403753A (de) Verfahren zur Herstellung von 6-Fluor- 4-steroiden der Androstan- oder Pregnanreihe bzw. von entsprechenden 19-Norverbindungen
CH368797A (de) Verfahren zur Herstellung von Androstanderivaten
CH487880A (de) Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH439281A (de) Verfahren zur Herstellung von 17a-Alkoxy-steroiden der Pregnanreihe
AT261816B (de) Verfahren zur Herstellung von neuen Guanylhydrazonen der Androstan- oder Pregnanreihe
AT256867B (de) Verfahren zur Herstellung neuer Benzolsulfonylharnstoffe und deren Salzen
AT310956B (de) Verfahren zur Herstellung von 9α-Fluor-16-methylen-4-pregnen-11β,17α-diol-3,20-dion und dessen 1(2)-Dehydroderivat
CH485689A (de) Verfahren zur mikrobiologischen Herstellung von 17-Oxosteroiden der Androstanreihe
AT280499B (de) Verfahren zur Herstellung neuer 4,6-Dichlor-Δ<4,6>-steroide der Pregnan- und Androstanreihe
AT253136B (de) Verfahren zur Herstellung von 3-Keto-Δ<4,6>-steroiden der Androstan- und Pregnanreihe
CH479566A (de) Verfahren zur Herstellung neuer 21-Ester von 1,4-16-Methylsteroiden
CH454136A (de) Verfahren zur Herstellung von substituierten Pregnenen und Pregnadienen
CH495967A (de) Verfahren zur Herstellung von Steroiden der Androstanreihe
CH518919A (de) Verfahren zur Herstellung von 9(11)-Dehydrosteroiden der Androstan- und Pregnanreihe
CH443284A (de) Verfahren zur Herstellung von Derivaten des Androstan
AT266344B (de) Verfahren zur Herstellung neuer Diaminosteroide
CH413835A (de) Verfahren zur Herstellung von 21-phosphorylierten Steroiden der Pregnanreihe
AT272540B (de) Verfahren zur mikrobiologischen Herstellung von Steroiden mit 1,4-Dien-3,17-dion-Struktur
AT257066B (de) Verfahren zur Herstellung von neuen Steroidverbindungen der Androstan- und Östranreihe
AT279065B (de) Verfahren zur Herstellung von neuem 4-Chlor-1,2α-methylen-Δ<4,6>-pregnadien-17α-ol-3,20-dion und dessen neuen 17-Estern
AT307637B (de) Verfahren zur Herstellung des 17 α-Hydroxypregna-4,9(11)-dien-3,20-dions
CH470372A (de) Verfahren zur Herstellung von 1,3,5(10)-19-nor-Steroiden der Androstan-, Pregnan- oder Spirostanreihe

Legal Events

Date Code Title Description
PL Patent ceased