CH478128A - Verfahren zur Herstellung von Pyrazinen - Google Patents

Verfahren zur Herstellung von Pyrazinen

Info

Publication number
CH478128A
CH478128A CH1397566A CH1397566A CH478128A CH 478128 A CH478128 A CH 478128A CH 1397566 A CH1397566 A CH 1397566A CH 1397566 A CH1397566 A CH 1397566A CH 478128 A CH478128 A CH 478128A
Authority
CH
Switzerland
Prior art keywords
pyrazines
preparation
Prior art date
Application number
CH1397566A
Other languages
English (en)
Inventor
Jethro Jr Cragoe Edward
Holden Jones James
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH478128A publication Critical patent/CH478128A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1397566A 1965-10-04 1966-09-28 Verfahren zur Herstellung von Pyrazinen CH478128A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US492862A US3341540A (en) 1965-10-04 1965-10-04 3-amino-6-halopyrazinonitriles and their syntheses

Publications (1)

Publication Number Publication Date
CH478128A true CH478128A (de) 1969-09-15

Family

ID=23957913

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1397566A CH478128A (de) 1965-10-04 1966-09-28 Verfahren zur Herstellung von Pyrazinen

Country Status (6)

Country Link
US (1) US3341540A (de)
BR (1) BR6683284D0 (de)
CH (1) CH478128A (de)
DE (1) DE1620035A1 (de)
GB (1) GB1149639A (de)
NL (1) NL6613934A (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4402959A (en) * 1980-06-02 1983-09-06 Merck & Co., Inc. Antimicrobial compositions
US4518599A (en) * 1982-09-30 1985-05-21 Merck & Co., Inc. 2-Amino-3-cyano-5-halo-6-(substituted)pyrazine
US4517186A (en) * 1982-09-30 1985-05-14 Merck & Co., Inc. 2-Amino-3,5-dicyano-6-(substituted)pyrazine antimicrobial compounds
US4442096A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 2-(Substituted)amino-3-cyano-5-halo-6-(substituted)-pyrazine antimicrobial compounds, compositions and use
US4442097A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use
US4481202A (en) * 1982-12-27 1984-11-06 Merek & Co., Inc. 2-Amino-3-carboxylate-5-halo-6-(substituted)pyrazine antimicrobial compounds
US4442095A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. N-[(5-Halo-2,6-(substituted)pyrazinyl)methylene]amine antimicrobial compounds, compositions and use
US4507299A (en) * 1982-12-27 1985-03-26 Merck & Co., Inc. N-[2-amino-5-halo-6-(substituted)-3-pyrazinyl)-methylene]amine antimicrobial compounds
US4512991A (en) * 1982-12-27 1985-04-23 Merck & Co., Inc. 3-Acyl-2-amino-5-halo-6-(substituted)pyrazine antimicrobial compounds
DE3372437D1 (en) * 1983-07-28 1987-08-20 Merck & Co Inc Antimicrobial compositions
US4479953A (en) * 1983-08-25 1984-10-30 Merck & Co., Inc. Pyrazine aldimine compounds as antimicrobial agents
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
US9593084B2 (en) 2012-12-17 2017-03-14 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity
WO2014099673A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
NL6613934A (de) 1967-04-05
BR6683284D0 (pt) 1973-12-26
GB1149639A (en) 1969-04-23
DE1620035A1 (de) 1970-02-12
US3341540A (en) 1967-09-12

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Legal Events

Date Code Title Description
PL Patent ceased